Abstract:
:A sesquiterpenoid quinone, epi-ilimaquinone (1), and two sesquiterpene amino quinones, smenospongine (2) and glycinylilimaquinone (3), were isolated from the Fijian marine sponge Hippospongia sp. The structures of these compounds were determined by spectroscopic analysis. Compounds 1 and 3 were reported for the first time in this study from the sponge of the genus Hippospongia. Compound 1 displayed potent cytotoxic activity and showed antibacterial activity against methicillin-resistant Staphylococcus aureus, wild type S. aureus and vancomycin-resistant Enterococcus faecium and displayed antifungal activity against amphotericin-resistant Candida albicans while compounds 2 and 3 showed moderate cytotoxic activity. However, compound 1 did not show appreciable antifungal activity against wild type C. albicans, Cryptococcus neoformans, Aspergillus niger, Penicillium sp., Rhizopus sporangia or Sordaria sp.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Kumar R,Subramani R,Aalbersberg Wdoi
10.1080/14786419.2012.722086subject
Has Abstractpub_date
2013-01-01 00:00:00pages
1488-91issue
16eissn
1478-6419issn
1478-6427journal_volume
27pub_type
杂志文章abstract::Nine resorcinol derivatives including two new ones, 5-[(8Z,11Z,14Z)-nonadeca-8,11,14-trienyl] resorcinol (1) and 5-[(8Z,11Z,14E)-heptadeca-8,11,14-trienyl] resorcinol (2), were isolated from the leaves of Syzygium samarangense. The new structures were elucidated by means of extensive spectroscopic techniques including...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1805606
更新日期:2020-08-13 00:00:00
abstract::This study was aimed at characterising the secondary metabolites responsible for antibacterial and antioxidant activities of Acalypha wilkesiana. Purification of the defatted methanol leaves extract was guided by the DPPH free radical scavenging assay as well as by evaluation of the antibacterial activity against four...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983105
更新日期:2015-01-01 00:00:00
abstract::Both enantiomers of the polyketide-derived lactone citreofuran (4) have been prepared. The enantiopure building blocks were obtained on a chemoenzymatic route ((S)-6) and by a chiral pool synthesis ((R)-6). The crucial step in the synthesis, a macrolactonization, was accomplished under Mitsunobu conditions. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1478641031000137004
更新日期:2003-08-01 00:00:00
abstract::A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compoun...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1765339
更新日期:2020-05-13 00:00:00
abstract::A new benzophenone huanglongmycin (HLM) D (1) and two new monomeric xanthones huanglongmycin E (2) and F (3), together with four known aromatic polyketides aloesaponarin II (4) and the previously isolated huanglongmycin A-C (5-7) were obtained from cave-derived Streptomyces sp. CB09001. The structures of 1-3 were esta...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1813134
更新日期:2020-09-01 00:00:00
abstract::The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983918
更新日期:2015-01-01 00:00:00
abstract::Eight phenolic compounds, including two mixtures of two compounds, were isolated from the ethyl acetate extract of leaves and stems of Homalium brachybotrys. They were identified on the basis of spectroscopic data as quercetin-3-O-beta-glucopyranoside, luteolin-7-O-beta-glucopyranoside, 5,6-dihydro-6-beta-glucopyranos...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601130679
更新日期:2007-11-01 00:00:00
abstract::The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1226828
更新日期:2017-01-01 00:00:00
abstract::Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.971790
更新日期:2015-02-01 00:00:00
abstract::One new neolignan glycoside, dolomiside A (1), together with 11 known phenylpropanoid glycosides were isolated from Dolomiaea souliei (Franch.) Shih. The structures of these isolates were determined by UV, CD, HR-ESI-TOFMS, 1D and 2D NMR analysis. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1552695
更新日期:2020-04-01 00:00:00
abstract::A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( - )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.988620
更新日期:2015-01-01 00:00:00
abstract::A new 24-membered macrolide, 5'-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insectici...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1405401
更新日期:2019-03-01 00:00:00
abstract::Two novel benzoquinones, uvarmicranones A (1) and B (2), along with 15 known compounds (3 - 17) were isolated from the stems of Uvaria micrantha (Annonaceae). Their structures were elucidated by analyses of NMR and high-resolution mass data. A plausible biosynthetic pathway of uvarmicranone A (1) via Diels-Alder cyclo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1824221
更新日期:2020-09-22 00:00:00
abstract::A new xanthone named cratoxylumxanthone A (1), together with five known compounds: dulcisxanthone B (2), alpha-mangostin (3), beta-mangostin (4), 2-geranyl-1,3,7-trihydroxy-4-(3-methylbut-2-enyl)xanthone (5) and tectochrystin (6), was isolated from Cratoxylum cochinchinense stems. The structure of new compound was cha...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601102033
更新日期:2006-12-01 00:00:00
abstract::A new benzophenone glycoside, mitraphenone A (1), together with three known compounds (2-4) were isolated from the leaves of the traditionally used medicinal plant Mitracarpus villosus (Rubiaceae) collected in Nigeria. A combination of one- and two-dimensional NMR spectroscopic and mass spectrometric measurements were...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1306701
更新日期:2017-10-01 00:00:00
abstract::N-methylasimilobine (1), a new-found strong acetylcholinesterase (AChE) inhibitor, along with two weakly active aporphine alkaloids, nuciferine (2) and nornuciferine (3) were separated from Nelumbo nucifera. N-methylasimilobine (1) inhibited 50% of AChE activity at the concentrations of 1.5 ± 0.2 µg mL(-1) when the st...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.487188
更新日期:2012-01-01 00:00:00
abstract::In an attempt to establish the components responsible for the use of Enantia chlorantha against cutaneous leishmaniasis in local traditional medicine, a well-known palmatine has been isolated in substantial amounts from a methanolic bark extract of this plant species. Palmatine therein obtained exhibited a significant...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902726241
更新日期:2009-01-01 00:00:00
abstract::A series of novel hydrocarbylidene nitrohydrazinecarboximidamides were designed and synthesized using an insecticidal natural product Galegine as a lead compound. The bioassay results show that the target compounds exhibited moderate to good insecticidal activities against Hyalopterus pruni Geoffroy at a concentration...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1655409
更新日期:2019-08-20 00:00:00
abstract::A new diterpenoid, 15-epi-(4E)-jatrogrossidentadione acetate, along with several known constituents has been isolated from the stem of Jatropha multifida. The structure of the new compound was settled by a detailed analysis of its 1D- and 2D-NMR spectra. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003792207
更新日期:2010-10-01 00:00:00
abstract::Chemical investigation of Dendrobium plicatile Lindl resulted in the isolation and identification of one new bibenzyl, 2-chloro-3, 4'-dihydroxy-3',5-dimethoxybibenzyl (1), as well as 15 known stilbenoids. The structures of this new compound was elucidated by extensive spectroscopic analysis, including HRESIMS, 1H and ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1530996
更新日期:2020-02-01 00:00:00
abstract::In this computational study, geometric factors are calculated by applying semi-empirical methods (PM3) that support experimental evidence from this lab where bryostatins can bind trivalent iron with six Fe-O bonds forming an octahedral geometry. The geometric factors are calculated for all 20 structures (Fe3+ bound to...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701590087
更新日期:2008-03-20 00:00:00
abstract::An eremophilane-type sesquiterpenoid (EPS), 3-oxo-eremophila-1,7(11)-dien-12,8β-olide, has been isolated from anti-inflammatory folk herbs, Ligularia pleurocaulis. The aim of present study is to explore protective effects of EPS on lipopolysaccharide (LPS)-induced inflammatory responses in acute lung injury (ALI). EPS...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1736068
更新日期:2020-03-31 00:00:00
abstract::Lavandin (Lavandula × intermedia Emeric ex Loiseleur) essential oils (EOs), from Abrial, Super and Grosso cultivars, cultivated and extracted in the South East of Spain, were analysed by using GC/MS to determine their composition, in both relative (peak area) and absolute (using standard curves) concentrations. Linalo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1043632
更新日期:2016-01-01 00:00:00
abstract::The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410412331280032
更新日期:2005-06-01 00:00:00
abstract::Essential oils hydrodistilled from the leaves and stem barks of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. growing in Vietnam were analysed by gas chromatography (GC) and GC-coupled with mass spectrometry. α-Pinene (1.7-50.0%), β-pinene (tr-6.8%),...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.814051
更新日期:2013-01-01 00:00:00
abstract::One new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the g...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1299731
更新日期:2017-10-01 00:00:00
abstract::A new dolabellane diterpenoid (1R*,3E,7E,9S*,11S*,12Z)-9-hydroxydolabella-3,7,12-triene (1), along with seven known compounds (2-8), has been isolated from the Hainan soft coral Spongodes sp. Their structures were elucidated on the basis of spectroscopic analysis and compared with those previously reported in literatu...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601130034
更新日期:2007-08-01 00:00:00
abstract::A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1410814
更新日期:2018-10-01 00:00:00
abstract::Moringa oleifera Lam. family Moringaceae is well known for a wide range of biological activities and a complex phytochemical composition. The current study investigates tissue culture protocols for Moringa oleifera leaves and seeds. For static culture initiation, Murashige and skooge (MS) as a basal medium with hormon...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1744137
更新日期:2020-03-25 00:00:00
abstract::The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1619721
更新日期:2021-01-01 00:00:00