Abstract:
:A new benzophenone huanglongmycin (HLM) D (1) and two new monomeric xanthones huanglongmycin E (2) and F (3), together with four known aromatic polyketides aloesaponarin II (4) and the previously isolated huanglongmycin A-C (5-7) were obtained from cave-derived Streptomyces sp. CB09001. The structures of 1-3 were established based on 1D, 2D NMR and HRMS data. Compounds 1-7 may be biosynthesized by a type II huanglongmycin polyketide synthase based on gene inactivation of hlmG encoding KSɑ in hlm gene cluster and their plausible biosynthetic mechanism was proposed.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Jiang L,Xiang J,Zhu S,Tang D,Gong B,Pu H,Duan Y,Huang Ydoi
10.1080/14786419.2020.1813134subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1-9eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::Fourteen wild strains of Staphylococcus aureus positive for gene sea were tested for enterotoxins production and the minimum inhibitory concentration of Leptospermum scoparium, Origanum majorana, Origanum vulgare, Satureja montana and Thymus vulgaris essential oils (EOs) were determined. After this trial, bacteria str...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1338284
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abstract::Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemic...
journal_title:Natural product research
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journal_title:Natural product research
pub_type: 杂志文章
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doi:10.1080/14786419.2010.551755
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journal_title:Natural product research
pub_type: 杂志文章
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abstract::The essential oil of Cyclospermum leptophyllum (Pers.) Sprague ex Britton and P. Wilson syn. Apium leptophyllum (Pers.) F. Muell. Ex Benth., family Apiaceae (Umbellifereae), was analysed by GC and GC-MS. The essential oil showed the presence of thymohydroquinone dimethyl ether (50.7%), thymol methyl ether (11.2%), γ-t...
journal_title:Natural product research
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journal_title:Natural product research
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abstract::Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...
journal_title:Natural product research
pub_type: 杂志文章
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journal_title:Natural product research
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doi:10.1080/1478641031000104136
更新日期:2003-06-01 00:00:00
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journal_title:Natural product research
pub_type: 杂志文章
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journal_title:Natural product research
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doi:10.1080/14786419.2017.1303699
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journal_title:Natural product research
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doi:10.1080/14786419.2017.1350673
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journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.599806
更新日期:2012-01-01 00:00:00
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journal_title:Natural product research
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journal_title:Natural product research
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journal_title:Natural product research
pub_type: 历史文章,杂志文章
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abstract::The Nigerian and South African varieties of Siphonochilus aethiopicus were examined for their phytochemical constituents. The ethyl acetate extract of the rhizomes of the South African variety yielded a novel diarylheptanoid, 2,3-diacetoxy-7-(3'',4''-dihydroxy-5''-methoxyphenyl)-1-(4'-hydroxy-3'-methoxyphenyl)-5-hepte...
journal_title:Natural product research
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journal_title:Natural product research
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更新日期:2015-02-01 00:00:00
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journal_title:Natural product research
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journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1311892
更新日期:2018-04-01 00:00:00
abstract::A new oleanane triterpenoid (2) was isolated from the roots of Rubia philippinensis. The structure of 2 was determined by analysis of HRMS and NMR data and identified as a rubiprasin analogue, 16β-hydroxyrubiprasin B. Four related known compounds were also encountered which include rubiprasin B (1), maslinic acid (3),...
journal_title:Natural product research
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更新日期:2019-07-25 00:00:00
abstract::Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1591396
更新日期:2019-03-31 00:00:00
abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...
journal_title:Natural product research
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doi:10.1080/14786410903108951
更新日期:2010-08-01 00:00:00