Antibacterial and antioxidant constituents of Acalypha wilkesiana.

Abstract:

:This study was aimed at characterising the secondary metabolites responsible for antibacterial and antioxidant activities of Acalypha wilkesiana. Purification of the defatted methanol leaves extract was guided by the DPPH free radical scavenging assay as well as by evaluation of the antibacterial activity against four bacterial strains. As a result, geraniin, corilagin, quadrangularic acid M and shikimic acid were purified and isolated. Shikimic acid, reported for the first time from this plant, proved to be the major metabolite of the extract. All the four isolated compounds showed bactericidal activity against extended spectrum beta-lactamase-producing Klebsiella pneumoniae (700603), while corilagin was the single compound to exhibit antioxidant activity (IC50 53 μg/mL).

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Anokwuru CP,Sinisi A,Samie A,Taglialatela-Scafati O

doi

10.1080/14786419.2014.983105

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

1180-3

issue

12

eissn

1478-6419

issn

1478-6427

journal_volume

29

pub_type

杂志文章
  • A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex Du Roi.

    abstract::From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2-7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.1003929

    authors: Mai DT,Le TD,Nguyen TP,Phan NM,Nguyen HA,Nguyen TT,Tran le Q

    更新日期:2015-01-01 00:00:00

  • Optimisation of the recovery of carotenoids from tomato processing wastes: application on textile dyeing and assessment of its antioxidant activity.

    abstract::The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1226828

    authors: Baaka N,El Ksibi I,Mhenni MF

    更新日期:2017-01-01 00:00:00

  • Characteristics of evodiamine-exerted stimulatory effects on rat jejunal contractility.

    abstract::This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.947485

    authors: Xiong YJ,Chen DP,Peng JY,Wang JY,Lv BC,Liu FF,Lin Y

    更新日期:2015-01-01 00:00:00

  • Hexane fraction from Brazilian Morus nigra leaves improved oral carbohydrate tolerance and inhibits α-amylase and α-glucosidase activities in diabetic mice.

    abstract::Morus nigra, popularly known as mulberry, has been traditionally used as anti-diabetic herbal medication. This study focused on hexane fraction from Brazilian M. nigra leaves (Hex-Mn) effects on digestion and absorption of carbohydrate in diabetic mice. The high-performance liquid chromatography (HPLC) analysis was pe...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1723087

    authors: Silva DHAD,Barbosa HM,Beltrão RLA,Silva CFO,Moura CA,Castro RN,Almeida JRGDS,Gomes DA,Lira EC

    更新日期:2020-02-24 00:00:00

  • Protective effects of baicalin and quercetin on an iron-overloaded mouse: comparison of liver, kidney and heart tissues.

    abstract::Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.495070

    authors: Zhang Y,Gao Z,Liu J,Xu Z

    更新日期:2011-07-01 00:00:00

  • A new monoterpene glycoside from Siparuna thecaphora.

    abstract::Phytochemical investigation of the extracts of the leaves of Siparuna thecaphora (Poepp. et Endl.) A. DC. (Siparunaceae) allowed the isolation of one monoterpene glycoside, named trans-thujane-1α,7-diol 1-O-β-D-glucopyranoside (1) along with rutin, quercetin 3-O-β-D-glucopyranoside and 3,4-dihydroxybenzaldehyde. Their...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.843179

    authors: Vera Saltos MB,Naranjo Puente BF,Malafronte N,Braca A

    更新日期:2014-01-01 00:00:00

  • Semi-preparative HPLC purification of δ-tocotrienol (δ-T3) from Elaeis guineensis Jacq. and Bixa orellana L. and evaluation of its in vitro anticancer activity in human A375 melanoma cells.

    abstract::In this work, we report a rapid and convenient HPLC-UV-DAD method for the isolation of δ-T3 on semi-preparative scale from two different vitamin E rich processed, commercially available products obtained from the fruits of Elaeis guineensis Jacq. (oil palm) and from the seeds of Bixa orellana L. (achiote tree). Chroma...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1320793

    authors: Beretta G,Gelmini F,Fontana F,Moretti RM,Montagnani Marelli M,Limonta P

    更新日期:2018-05-01 00:00:00

  • Bioactive oligostilbenoids from Shorea maxwelliana King and their chemotaxonomic significance.

    abstract::Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic ac...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.730047

    authors: Zawawi NK,Ahmat N,Mazatulikhma MZ,Shafiq RM,Wahid NH,Sufian AS

    更新日期:2013-01-01 00:00:00

  • Malva sylvestris derivatives as inhibitors of HIV-1 BaL infection.

    abstract::The emphasis of the present study is to evaluate a natural product and the potential microbicide activity using a dual chamber infection method. Malva sylvestris extracts and fractions were screened for anti-HIV activity by measuring the virus-antibody neutralization. Plant extracts with strong antiviral activity work...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1619720

    authors: Benso B,Rosalen PL,Pasetto S,Marquezin MCS,Freitas-Blanco V,Murata RM

    更新日期:2019-08-20 00:00:00

  • Excelsanone, a new isoflavonoid from Erythrina excelsa (Fabaceae), with in vitro antioxidant and in vitro cytotoxic effects on prostate cancer cells lines.

    abstract::A new isoflavonoid, excelsanone (2), was isolated from the ethyl acetate extract of Erythrina excelsa stem bark, together with three known compounds namely 6,8-diprenylgenistein (3), β-sitosterol (1) and sitosteryl-β-D-glucopyranoside (4). Their structures were elucidated using spectroscopic methods (HR-ESI-MS, NMR an...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1495639

    authors: Gbaweng AJY,Daïrou H,Zingué S,Emmanuel T,Tchinda AT,Frédérich M,Mbafor JT

    更新日期:2020-03-01 00:00:00

  • Potential beneficial and/or adverse effects of Capsicum annuum L. (cv. Fiesta) at two stage of ripening in CD-1 mice.

    abstract::Aim of the present study was to evaluate the potential beneficial and/or adverse effects of Capsicum annuum L. (cv. Fiesta) extracts at two stage of ripening (immature and mature), and at two dosages (low and high) by evaluation of biochemical profile and oxidative status in CD-1 mice. The extracts were daily administ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1525371

    authors: Morittu VM,Pero ME,Musco N,Mastellone V,Tudisco R,Provenzano E,Britti D,Menichini F,Infascelli F,Lombardi P

    更新日期:2020-06-01 00:00:00

  • Metabolite and mineral profiling of "Violetto di Niscemi" and "Spinoso di Menfi" globe artichokes by 1H-NMR and ICP-MS.

    abstract::Globe artichoke has been long considered a nutraceutical food for its valuable content of bioactive compounds. However, beside a well-known polyphenol profile, poor information is available about its metabolite and mineral composition. The aim of this study was to investigate edible parts of Sicilian artichokes, 'Spin...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1258563

    authors: Albergamo A,Rotondo A,Salvo A,Pellizzeri V,Bua DG,Maggio A,Cicero N,Dugo G

    更新日期:2017-05-01 00:00:00

  • Incorporation of Baccharis dracunculifolia DC (Asteraceae) leaf extract into phosphatidylcholine-cholesterol liposomes improves its anti-inflammatory effect in vivo.

    abstract::The aerial parts of Baccharis dracunculifolia (BdE) is used in the Brazilian folk medicine to treat inflammatory conditions. Here we examined the ability of free and liposomal BdE to modulate reactive oxygen species generation in human neutrophils in vitro and zymosan-induced acute joint inflammation in Wistar rats. W...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1448809

    authors: de Figueiredo-Rinhel ASG,de Andrade MF,Landi-Librandi AP,Azzolini AECS,Kabeya LM,Bastos JK,Lucisano-Valim YM

    更新日期:2019-09-01 00:00:00

  • Briarenol A, a new diterpenoid from a gorgonian '\Briareum sp. (Briareidae).

    abstract::A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410512331330611

    authors: Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

    更新日期:2005-10-01 00:00:00

  • Comparison of cytotoxicity and DNA damage potential induced by ent-kaurene diterpenoids from Isodon plant.

    abstract::The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802267734

    authors: Ding L,Zhou Q,Wang L,Wang W,Zhang S,Liu B

    更新日期:2011-09-01 00:00:00

  • Insecticidal activity of the essential oil of Perovskia artemisioides Boiss.

    abstract::This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1803311

    authors: Sadeghi Z,Alizadeh Z,Khorrami F,Norouzi S,Moridi Farimani M

    更新日期:2020-08-26 00:00:00

  • Sesquiterpene-neolignans from Manglietia hookeri.

    abstract::The comet assay-guided fractionation of the twigs of Manglietia hookeri resulted in the isolation of three sesquiterpene-neolignans, including a new one 5-allyl-2-(4-allyl-phenoxy)-3-[7-(1-hydroxy-1-methyl-ethyl)-1, 4a-dimethyl-decahydro-naphthalen-1-yloxy]-phenol (1), and eudesobovatol A (2) and eudesobovatol B (3), ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1110703

    authors: Hu X,Sui X,Wang Y,Wang W,Wu H,Zhang F,Tan Y,Zhang F

    更新日期:2016-07-01 00:00:00

  • Two new naphthylisoquinoline alkaloids from stems and leaves of Ancistrocladus tectorius.

    abstract::Two new alkaloids, 4'-O-demethylhamatine (1) and ancistrotectoriline C (2), were isolated from the stems and leaves of Ancistrocladus tectorius. These two compounds represent one 5,1'-coupled and one 7,6'-coupled naphthylisoquinoline alkaloid, respectively. Their structures were elucidated by 1D- and 2D-NMR spectra an...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410902836727

    authors: Tang CP,Xin ZQ,Li XQ,Ye Y

    更新日期:2010-07-01 00:00:00

  • Two new monoterpene glucosides from Xanthium strumarium subsp. sibiricum with their anti-inflammatory activity.

    abstract::Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1479701

    authors: Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

    更新日期:2019-12-01 00:00:00

  • A new triterpenoid glucoside from Leucas zeylanica.

    abstract::A new triterpenoid glucoside, leuctriterpencoside (1), along with two known compounds (2-3) were isolated from Leucas zeylanica. The structure of the new compound was elucidated using comprehensive spectroscopic methods. Compound 1 showed significant inhibitory activity against α-glucosidase (IC50 value of 0.85 ± 0.12...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1566820

    authors: Chen GY,Zhang B,Zhao T,Nidhal N,Jia-Li W,Zhou XM,Chun-Yan D

    更新日期:2020-07-01 00:00:00

  • Antibacterial activity and composition of the essential oil of Nepeta hormozganica Jamzad from Iran.

    abstract::The composition and antibacterial activity of the essential oil of the aerial flowering parts of Nepeta hormozganica Jamzad have been studied. Analysis of the oil was conducted by GC-FID and GC-MS. Thirty-two components were characterized accounting for 99.4% of the total oil. Oxygenated monoterpenes (87.5%) were foun...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1295237

    authors: Sonboli A,Saadat MH,Arman M,Kanani MR

    更新日期:2017-12-01 00:00:00

  • Plants of the Russian Federation pharmacopeia: an unexhausted natural products research opportunity?

    abstract::32 medicinal plants that are unique to the Russian Pharmacopeia have 693 isolated natural products associated with them (an average of 21.66 compounds per plant). This is in contrast to the US Pharmacopeia plants that have delivered 2366 known natural products (an average of 42.25 compounds per plant). ...

    journal_title:Natural product research

    pub_type: 信件

    doi:10.1080/14786419.2020.1727474

    authors: Chupakhin E,Babich O,Prosekov A,Asyakina L,Gureev M,Krasavin M

    更新日期:2020-02-21 00:00:00

  • Chemical constituents and antibacterial activity of Melastoma malabathricum L.

    abstract::The aqueous methanolic extracts of Melastoma malabathricum L. exhibited antibacterial activity when assayed against seven microorganisms by the agar diffusion method. Solvent fractionation afforded active chloroform and ethyl acetate fractions from the leaves and the flowers, respectively. A phytochemical study result...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.538395

    authors: Wong KC,Hag Ali DM,Boey PL

    更新日期:2012-01-01 00:00:00

  • Xylaolide A, a new lactone from the fungus Xylariaceae sp. DPZ-SY43.

    abstract::Chemical investigation of the fungus Xylariaceae sp. DPZ-SY43 has led to the isolation of a new compound, xylaolide A (1) together with three known compounds (2-4). The structures were established by analysing the spectroscopic data. Compound 1 was evaluated for its cytotoxicity. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.901318

    authors: Yang B,Dong J,Lin X,Tao H,Zhou X,Liu Y

    更新日期:2014-01-01 00:00:00

  • A modified oligostilbenoid, diptoindonesin C, from Shorea pinanga Scheff.

    abstract::A new oligostilbenoid, diptoindonesin C, has been isolated from the tree bark of Shorea pinanga Scheff., along with the two known oligostilbenoids gnetin H and hopeaphenol, and a known coumarin scopoletin. The new oligostilbenoid was moderately active against brine shrimps Artemia salina. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410600761235

    authors: Syah YM,Hakim EH,Ghisalberti EL,Jayuska A,Mujahidin D,Achmad SA

    更新日期:2009-01-01 00:00:00

  • Polyphenolics from Gymnocarpos decandrus Forssk roots and their biological activities.

    abstract::Phytochemical investigation of Gymnocarpos decandrus roots lead to the isolation, characterization and evaluation of four compounds: the bis-coumarin daphnoretin, two biflavonoids: wikstrol A and wikstol B in addition to β-sitosterol glucoside. Their structures were established via spectroscopic data. The crude root e...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1607336

    authors: Fathy H

    更新日期:2019-05-13 00:00:00

  • Endemic species of sardo-corso-balearic area: molecular composition and biological assay of Teucrium.

    abstract::Teucrium marum and T. subspinosum have been extracted with different polarity solvents, each crude extract was analysed with (1)H-NMR to compare the overall metabolic component. The polar extracts showed antioxidant activity in vitro. Verbascoside and arabinosyl-verbascoside were isolated and identified. Their concent...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701571384

    authors: Poli F,Serrilli AM,Scartezzini P,Muzzoli M,Maxia A,Ballero M,Serafini M,Bianco A

    更新日期:2007-10-01 00:00:00

  • Biological studies of azadirachtin and its derivatives against polyphagous pest, Spodoptera litura.

    abstract::Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410512331330558

    authors: Deota PT,Upadhyay PR

    更新日期:2005-07-01 00:00:00

  • New anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3.

    abstract::A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6'-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures w...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1480621

    authors: Pang X,Wang LM,Zhang YC,Kang LP,Yu HS,Fan GW,Han LF

    更新日期:2019-12-01 00:00:00

  • Nortirucallane A, a new tirucallane-type nortriterpenoid isolated from Lonicerae japonicae flos.

    abstract::One new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the g...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1299731

    authors: Wang X,Zhang J,Li YQ,Du BX,Sun QH,Cao YJ,Jiang HQ,Liu YH,Zhou HL,Rong R

    更新日期:2017-10-01 00:00:00