Abstract:
:A new triterpenoid glucoside, leuctriterpencoside (1), along with two known compounds (2-3) were isolated from Leucas zeylanica. The structure of the new compound was elucidated using comprehensive spectroscopic methods. Compound 1 showed significant inhibitory activity against α-glucosidase (IC50 value of 0.85 ± 0.12 μM).
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Chen GY,Zhang B,Zhao T,Nidhal N,Jia-Li W,Zhou XM,Chun-Yan Ddoi
10.1080/14786419.2019.1566820subject
Has Abstractpub_date
2020-07-01 00:00:00pages
1874-1878issue
13eissn
1478-6419issn
1478-6427journal_volume
34pub_type
杂志文章abstract::The ethanol extract of the Ficus carica L. leaves was tested to show strong nematicidal activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/mL. From the ethyl acetate soluble fraction of the F. carica L. leaves extract, the main nematicidal co...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1094804
更新日期:2016-09-01 00:00:00
abstract::From the ethanolic extract of Lentinus edodes (Shiitake) eight known sterols were isolated and identified: ergosterol, ergosterol peroxide, (22E)-ergosta-5,7,9(11), 22-tetraen-3beta-ol, (22E)-ergosta-7,9(11),22-trien-3beta-ol, (22E)-ergosta-6,8,22-trien-3beta-ol, (22E)-norergosta-5,7,9,22-tetraen-3beta-ol, 3beta,5alph...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802038671
更新日期:2009-01-01 00:00:00
abstract::Chemical investigation of the root bark of Morus alba led to the isolation of a new flavone, dioxycudraflavone A (1) and a new 2-arylbenzofuran, 5-hydroxyethyl moracin M (2), together with seven known compounds namely sanggenon V (3), morusin (4), morusignin L (5), licoflavone C (6), moracin C (7), alfafuran (8) and m...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1327862
更新日期:2018-01-01 00:00:00
abstract::Two new 19-hydroxy bufadienolides, named bufohydrolide A (1) and bufohydrolide B (2), and four known analogs (3-6) were isolated from the aqueous extracts of the skins of Bufo melanosticus. Their structures were established by spectral data analyses, such as UV, IR, 1 D/2D NMR and mass spectra. Compounds 1-6 were eval...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1741582
更新日期:2020-03-23 00:00:00
abstract::Alzheimer's disease (AD) is a multifactorial health problem widespread over the world. Regarding the historical importance of the alkaloids in the central nervous system pharmacology they remain as promising drug candidates against AD. Seven alkaloids from Amaryllidaceae and Fabaceae were evaluated in vivo, in vitro a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1727471
更新日期:2020-02-18 00:00:00
abstract::Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1350673
更新日期:2018-06-01 00:00:00
abstract::Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.495070
更新日期:2011-07-01 00:00:00
abstract::Alphitobius diaperinus is an important pathogen with worldwide distribution that causes severe economic loss of efficiency in broilers. This study evaluates the potential of organic extracts of two strains entomopathogenic fungus Beauveria bassiana (CG71 and UNI40) as a biocontrol agent on A. diaperinus and promotes t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1514396
更新日期:2019-10-01 00:00:00
abstract::A series of unexpected triterpenic C17-[5-methyl-1,3]-oxazoles along with targeted N-propargylamides was synthesized by an interaction of acid chlorides with propargylamine hydrochloride. We proposed that the formation of methyl oxazole passes through an alternative pathway by the participation of the terminal alkyne ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1744139
更新日期:2020-03-28 00:00:00
abstract::The chemical composition of the essential oils isolated from the aerial parts of Anthemis arvensis L. subsp. arvensis, Anthemis cretica subsp. messanensis (Brullo) Giardina & Raimondo and from flowers and leaves of Anthemis cretica subsp. columnae (Ten.) Frezén were determinated by GC-FID and GC-MS analyses. Torreyol ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1297444
更新日期:2017-12-01 00:00:00
abstract::Three new methylated flavonol glucosides: 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) quercetin (1), 3,4'-dimethoxy-7-O-β-(6″-galloyl-glucopyranoside) quercetin (2) and 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) kaempferol (3), in addition to six known flavonols, were isolated from the ethyl acetate extract of Fuma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.778848
更新日期:2013-01-01 00:00:00
abstract::Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1297442
更新日期:2017-10-01 00:00:00
abstract::The microbial transformation of androst-4-ene-3,17-dione (4-AD; I) by three fungal species, involved Fusarium solani BH1031, Aspergillus awamori MH18 and Mucor circinelloides W12, has been studied. The latter two fungi were studied for the first time on biotransformation of 4-AD. The main product obtained by Fusarium ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1636238
更新日期:2021-02-01 00:00:00
abstract::Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1737052
更新日期:2020-03-11 00:00:00
abstract::The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1647427
更新日期:2019-08-12 00:00:00
abstract::In the present study, the chemical composition of the essential oil from the aerial parts of Anthemis secundiramea Biv. subsp. secundiramea L. collected in Sicily was evaluated by GC and gas chromatography-mass spectrometry. The main components of A. secundiramea were (Z)-lyratyl acetate (14.6%), (Z)-chrysanthenyl ace...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1166497
更新日期:2019-04-01 00:00:00
abstract::Leishmaniasis is caused by parasites of the genus Leishmania. Recent reports about leishmaniasis show a few number of drugs available, indicating the necessity of new drugs. In this study, the ethanol extract and fractions of Pityrogramma calomelanos (L.) link. (Pteridaceae) were assayed to verify the cytotoxicity and...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.686911
更新日期:2013-01-01 00:00:00
abstract::Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1465423
更新日期:2019-04-01 00:00:00
abstract::The stem-derived essential oil of Aglaia odorata Lour. was obtained by hydrodistillation using a Clevenger-type system. Gas chromatography-mass spectrometry analysis of the oil revealed the identification of 39 compounds, representing 76.4% of the oil; germacrene D (20.3%), α-humulene (17.1%), α-himachalene (12.7%) an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.924934
更新日期:2014-01-01 00:00:00
abstract::As part of our continuing efforts to explore bioactive compounds from natural resources, a new iridoid glycoside, adoxosidic acid-6'-oleuroperic ester (1), together with one known phenylethanoid glycoside (2) and two known flavonoid glycosides (3-4) were isolated from the fruit of Forsythia suspensa. The structure of ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1560288
更新日期:2020-05-01 00:00:00
abstract::A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, C (n) H(2) (n) (+1,) whe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.502896
更新日期:2012-01-01 00:00:00
abstract::A new dihydroisocoumarin (1) and a new coumarin (2), along with eight known metabolites (3-10), were isolated from the solid substrate fermentation cultures of the fungus Penicillium purpurogenum MHZ 111. Their structures were elucidated by extensive spectroscopic analysis and comparison of their spectroscopic and phy...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1207075
更新日期:2017-03-01 00:00:00
abstract::Two new briarane-type diterpenoids, dollfusilin A (1) and dollfusilin B (2), along with five known briarane-type diterpenoids (3-7), were isolated from the gorgonian Ellisella dollfusi collected from the South China Sea. The structures of the two new compounds (1 and 2) were elucidated through a comprehensive analysis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.827191
更新日期:2014-01-01 00:00:00
abstract::A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1679130
更新日期:2019-10-29 00:00:00
abstract::Cinobufagin was one of the important cardenolidal steroids and a major component of Chan'Su, a famous traditional Chinese medicine. The urinary metabolites of cinobufagin after single oral doses of 25 mg kg⁻¹ in rats were investigated. Eleven metabolites were isolated and purified by liquid-liquid extraction, open-col...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.510798
更新日期:2012-01-01 00:00:00
abstract::Penicillium polonicum MCCC3A00951 is a fungus with influenza neuraminidase (NA) inhibition activity derived from a sediment of the mangrove forest of Zhangjiangkou in Fujian province, China. Chemical investigation on an ethyl acetate extract of its fermentation led to the isolation of a new compound, 7-hydroxy-3,10-de...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1817015
更新日期:2020-09-14 00:00:00
abstract::Polyphenol concentrations were quantified by rapid resolution liquid chromatography/mass spectrometry in white table grape. The experimental vineyard was subjected to different kinds of water supply and supply rates. Samples from the same vineyards were also analysed after 6 weeks of storage in a refrigerator and afte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.606623
更新日期:2012-01-01 00:00:00
abstract::Eight known abietane diterpenes (1-8) were isolated for the first time from Abies numidica cones (Pinaceae). The structures of all compounds were established by means of 1D and 2D NMR, and UV spectral analyses. The hydromethanolic extract of A. numidica cones was tested for its antimicrobial activity against 17 gram-p...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1190723
更新日期:2017-03-01 00:00:00
abstract::A new prenylated xanthone, mangostanaxanthone VIII (7) and six known metabolites: gartanin (1), 1,3,8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl)-xanthone (2), rubraxanthone (3), 1,3,6,7-tetrahydroxy-8-prenylxanthone (4), garcinone C (5), and xanthone I (9-hydroxycalabaxanthone) (6) were separated...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446012
更新日期:2019-01-01 00:00:00
abstract::α-Mangostin is the major prenylated xanthone from Garcinia mangostana and it has been used also in recent times as starting material for the semisynthetic preparation of various biologically active derivatives. Its structure is characterised by the presence of few functional groups amenable to chemical manipulations, ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.986729
更新日期:2015-01-01 00:00:00