Therapeutic effects of soy isoflavones on α-amylase activity, insulin deficiency, liver-kidney function and metabolic disorders in diabetic rats.

abstract：:Citrinin dimeric derivatives are bioactive polyketides previously reported from Penicillium, Aspergillus and Monascus fungi species. Due to the large distance between the stereogenic centers of the two monomer units, it was difficult to determine the absolute configuration of the whole molecule (1). In previous work, ...

journal_title：Natural product research

authors： Cao F,Sun TT,Yang JK,Zhao GZ,Liu QA,Hu LD,Ma ZY,Zhu HJ

更新日期：2019-08-01 00:00:00

abstract：:A new pentacyclic triterpenoid fatty acid ester, lupan-20-ol-3(β)-yl hexadecanoate (1), together with lupan-20-ol-3(β)-yl acetate (2), olean-18-en-3(β)-yl hexadecanoate (3), dotriacontanoic acid (4), stigmasterol (5), rubiadin (6), nonadecanoic acid (7), palmitic acid (8) and camptothecin (9) were isolated from the he...

journal_title：Natural product research

authors： Rajan R,Venkataraman R,Baby S

更新日期：2016-10-01 00:00:00

abstract：:This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...

journal_title：Natural product research

authors： Xiong YJ,Chen DP,Peng JY,Wang JY,Lv BC,Liu FF,Lin Y

更新日期：2015-01-01 00:00:00

abstract：:Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

journal_title：Natural product research

authors： Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

更新日期：2019-09-30 00:00:00

abstract：:One new flavonoid, 5,7,8,4'-tetrahydroxy-3-methoxyflavone-8-O-β-d-xylopyranoside (2), along with other four known flavones (1, 3-5) were isolated from the aerial parts of Solanum rostratum. 8-hydroxyflavonoid was isolated from series Androceras for the first time. The structure of the new compound 2 was determined on ...

journal_title：Natural product research

authors： Huang HJ,Ling TJ,Wang HM,Cao AC,Zhang CX,Wei SH

更新日期：2017-08-01 00:00:00

abstract：:Investigations were performed on the determination of the main components in Berchemia lineata (L.) DC. (BL) and its metabolism with human liver microsomes (HLM). A total of 35 compounds were detected in BL extracts and 25 of them including 6 naphthopyrones, 10 flavonoids, 2 phenolic acids, 2 phenols, 4 fatty acids an...

journal_title：Natural product research

authors： Jiang X,Chen S,Guo Z,Gu D,Liang X

更新日期：2021-02-01 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00

abstract：:This study reports for the first time in the chemical composition of acetone, ether, ethyl acetate and dichloromethane extracts of Hypogymnia tubulosa determined by HPLC-UV, GC-FID and GC-MS as well as effect of H. tubulosa acetone extract on micronucleus distribution on human lymphocytes and on cholinesterase activit...

journal_title：Natural product research

authors： Stojanović G,Zlatanović I,Zrnzević I,Stanković M,Stankov Jovanović V,Zlatković B

更新日期：2018-11-01 00:00:00

abstract：:The antiplasmodial active extract of Xanthium cavanillesii contains 3,4-dicaffeoyl quinic acid (3,4-DCQA), 3,5-dicaffeoyl quinic acid (3,5-DCQA) and 1,3,5-tricaffeoyl quinic acid (1,3,5-TCQA). These results inspired us to investigate the interaction of these molecules with a promising validated target of Plasmodium, P...

journal_title：Natural product research

authors： Taranto AG,Costa SC,Leite FH,de Sá MS,Soares MB,Mussi MM,Branco A

更新日期：2017-03-01 00:00:00

abstract：:The structure of pregnane oligoglycosides, namely rocinine (1) and marsdinine (11), which have been isolated from the chloroform soluble extract of the dried stem of Marsdenia roylei, were elucidated using MS, (1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC and TOCSY experiments as well as chemical degradation and derivatis...

journal_title：Natural product research

authors： Gupta V,Kumar A,Khare A,Khare NK

更新日期：2009-01-01 00:00:00

abstract：:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...

journal_title：Natural product research

authors： Benkendorff K,Pillai R,Bremner JB

更新日期：2004-10-01 00:00:00

abstract：:Due to the increasing emergence of resistance of bacterial pathogens to current antibiotics, we have examined the marine fungi present in sea sediments obtained 200 m offshore to discover new antibacterial compounds active against multidrug-resistant bacteria. One strain, identified as Emericellopsis minima, was isola...

journal_title：Natural product research

authors： Inostroza A,Lara L,Paz C,Perez A,Galleguillos F,Hernandez V,Becerra J,González-Rocha G,Silva M

更新日期：2018-06-01 00:00:00

abstract：:The objective of this study was to determine whether endophytic fungi, isolated from Kadsura angustifolia produce nigranoic acid and its highly oxygenated derivatives. From the 426 endophytic fungi screened, Trichoderma harzianum SWUKD3.1610 was detected to have a component with the same TLC R ...

journal_title：Natural product research

authors： Han M,Qin D,Ye T,Yan X,Wang J,Duan X,Dong J

更新日期：2019-07-01 00:00:00

abstract：:One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...

journal_title：Natural product research

authors： Zhuang PY,Chen MH,Wang YN,Wang XX,Feng YJ,Zhang DY

更新日期：2018-10-01 00:00:00

abstract：:Waste deriving from food and agro-industries is a growing problem in our modern society. In order to reduce food waste and its associated impacts over the environment and public health, innovative strategies for the conversion of food wastes in added value products are studied. Whey is one of the prominent waste deriv...

journal_title：Natural product research

authors： Gervasi T,Pellizzeri V,Benameur Q,Gervasi C,Santini A,Cicero N,Dugo G

更新日期：2018-07-01 00:00:00

abstract：:Methanolic extracts of 18 Thai plants from Doi Tung, the north of Thailand, were examined for brine shrimp lethality and antioxidative activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. In brine shrimp lethality, the highly toxic plant extracts were Mitrephora wangii (LC(50) 14.8 µg mL(-1)) and Hydrocotyle jav...

journal_title：Natural product research

authors： Tanamatayarat P,Sotanaphun U,Poobrasert O

更新日期：2012-01-01 00:00:00

abstract：:Two new myrsinol-type diterpene polyesters 3,5,13,17-tetra-O-acetyl-7-O-benzoyl-15-hydroxymyrsinol (1) and 3,5,13,17-tetra-O-acetyl-7-O-butanoyl-13-hydroxymyrsinol (2), with a tricyclic carbon skeleton have been isolated from Euphorbia decipiens Boiss. & Buhse. The structure elucidation of the isolated compounds was b...

journal_title：Natural product research

authors： Ahmad VU,Hussain J,Hussain H,Farooq U,Farmanullah,Lodhi MA,Choudhary MI

更新日期：2005-04-01 00:00:00

abstract：:In this study, essential oil compositions of two Hypericum L. taxa (Hypericum triquetrifolium Turra. and Hypericum aviculariifolium Jaub. et Spach subsp. depilatum var. depilatum (Freyn et Bornm.) Robson) naturally grown in Turkey were determined using gas chromatography and gas chromatography-mass spectrometry system...

journal_title：Natural product research

authors： Yuce E,Bagci E

更新日期：2012-11-01 00:00:00

abstract：:Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in...

journal_title：Natural product research

authors： Yalcin G,Sogut O

更新日期：2014-01-01 00:00:00

abstract：:Illicium lanceolatum is a popular aromatic and medicinal plant in China. Essential oil from the roots of I. lanceolatum, obtained by hydrodistillation, was analysed by GC-MS. The essential oil was dominated by phenylpropenes. The major components were myristicin (17.63%), α-asarone (17.23%), methyl isoeugenol (11.19%)...

journal_title：Natural product research

authors： Liang J,Huang B,Wang G

更新日期：2012-01-01 00:00:00

abstract：:A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, C (n) H(2) (n) (+1,) whe...

journal_title：Natural product research

authors： Ngaini Z,Fadzillah SM,Hussain H

更新日期：2012-01-01 00:00:00

abstract：:The antiradical activity of the freshwater bryozoan Hyalinella punctata water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (√OH), superoxide anion (√O2(- )), methoxy (√CH2OH), carbon-dioxide anion (√CO2(- )), nitric-oxide (√NO) and 2,2...

journal_title：Natural product research

authors： Pejin B,Savic AG,Hegedis A,Karaman I,Horvatovic M,Mojovic M

更新日期：2014-01-01 00:00:00

abstract：:A short total synthesis of natural isocarbostyril ruprechstyril (3-n-pentyl-6-methoxy-8-hydroxy-1(2H)-isoquinolinone) isolated from Ruprechtia tangarana is reported. 6,8-Dimethoxy-3-pentylisocoumarin obtained by condensation of 3,5-dimethoxyhomophthalic anhydride with hexanoyl chloride was smoothly converted to O-meth...

journal_title：Natural product research

authors： Saeed A

更新日期：2013-01-01 00:00:00

abstract：:Two flavonoid glycosides containing acetylated allose, and two iridoid glucosides were obtained from a EtOH extract of Stachys corsica, an endemic plant of Sardinia and Corsica. All the compounds have previously been isolated from other species of Stachys. ...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M

更新日期：2005-09-01 00:00:00

abstract：:The chemical investigation of the extract of the dried leaves of Rauvolfia caffra (Sond) (synonym Rauvolfia macrophylla) (Apocynaceae) led to isolation of a new glycoside derivative, rauvolfianine (1) as well as six known compounds: oleanolic acid (2), sitosterol-3-O-β-D-glucopyranoside (3), betulinic acid (4), vellos...

journal_title：Natural product research

authors： Ebeh Messanga R,Dominique Serge NB,Abouem A Zintchem A,Norbert MNI,Esther Del Florence MN,Patrick Hervé BD,Maximilienne Ascension N,Alex De Théodore A,Dieudonné Emmanuel P,Christian G B,Koert U

更新日期：2018-08-01 00:00:00

abstract：:Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...

journal_title：Natural product research

authors： Silinsin M,Bursal E

更新日期：2018-06-01 00:00:00

abstract：:A phytochemical investigation on Lagotis brevituba led to the isolation and characterisation of 11 phenolic compounds: p-hydroxy-benzoic acid 1, methyl 3,4-dihydroxybenzoate 2, vanillic acid 3, protocatechuic acid 4, caffeic acid 5, glucose ester of (E)-ferulic acid 6, p-coumaric acid 7, vanillin 8, diosmetin-7-O-β-d-...

journal_title：Natural product research

authors： Yuan X,Wen H,Cui Y,Fan M,Liu Z,Mei L,Shao Y,Wang Y,Tao Y

更新日期：2017-02-01 00:00:00

abstract：:Pectins were isolated from bark, wood and pith of kenaf (Hibiscus cannabinus L.) variety Cuba108. Imidazole was used as extractant. The isolated pectins were studied by 13C nuclear magnetic resonance (13C-NMR) spectroscopy and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS). From the spectroscopic...

journal_title：Natural product research

authors： Pappas CS,Tarantilis PA,Polissiou MG

更新日期：2003-06-01 00:00:00

abstract：:Two new ent-atisanes ent-1β,3β,16β,17-tetrahydroxyatisane (1), ent-1β,3α,16β,17-tetrahydroxyatisane (2) together with 11 known diterpenes were isolated from the anti-tumour activity fraction of Euphorbia fischeriana Steud. The compounds were identified by detailed spectroscopic analysis, including extensive 2D-NMR exp...

journal_title：Natural product research

authors： Wang M,Wang Q,Wei Q,Li J,Guo C,Yang B,Kuang H

更新日期：2016-01-01 00:00:00

abstract：:Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group...

journal_title：Natural product research

authors： Tang P,Lin HX,Yuan TH,Cui YM

更新日期：2019-12-01 00:00:00