Antitumour activity of Prosopis cineraria (L.) Druce against Ehrlich ascites carcinoma-induced mice.

Abstract:

:The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation, antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, solid tumour mass and in vitro cytotoxicity. PCL and PCB were found to be potent and possessed significant cytotoxicity towards EAC tumour cells.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Robertson S,Narayanan N,Raj Kapoor B

doi

10.1080/14786419.2010.536159

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

857-62

issue

8

eissn

1478-6419

issn

1478-6427

pii

935885957

journal_volume

25

pub_type

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