A new squalene derivative from Physalis angulata L. (Solanaceae).

Abstract:

:Physalis angulata is an annual herb which has tremendous medicinal uses. The antioxidant activity of the whole plant extract of Physalis angulata was investigated using DPPH radical scavenging activity. Purified compounds were isolated using column chromatography method. Their structures were determined using various spectroscopic techniques. A new compound named as Squalen-1-ol, Phytol, squalene and α-tocopherol were isolated. These compounds were isolated for the first time from Physalis angulata. The extract of Physalis angulata gave a significant IC50 value of 0.77 mg/mL as compared with the standard ascorbic acid with IC50 value of 0.24 mg/mL. It can be correlated that the antioxidant activity of Physalis angulata could be attributed to the presence of α - tocopherol which is a known antioxidant. The presence of these compounds gives a further added pharmacological value to the plant.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Odusina BO,Onocha PA

doi

10.1080/14786419.2020.1844691

subject

Has Abstract

pub_date

2020-11-23 00:00:00

pages

1-4

eissn

1478-6419

issn

1478-6427

pub_type

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