Evaluation of the antioxidant and anti-inflammatory activities of solvent extracts of Tricholepis chaetolepis (Boiss) Rech. f. whole plant.

Abstract:

:The whole plant, Tricholepis chaetolepis, powder was investigated using proximate and fluorescence analysis along with determining the extractive values. Total phenolics, flavonoids and total protein contents of n-hexane, chloroform and methanolic extracts of the whole plant were also determined. The anti-diabetic activity of all the three extracts of the plant was determined by in vitro alpha-amylase inhibition assay. The anti-oxidant potential was evaluated using Phosophomolybdenum and DPPH methods. The anti-inflammatory potential of all extracts were determined by carrageenan-induced rat paw oedema model. The evaluation of the plant extracts exhibited the anti-diabetic, anti-oxidant, and anti-inflammatory activities in dose dependent fashion. The research concludes that Tricholepis chaetolepis extracts contain phenol, flavonoids, and tannins that show observable anti-oxidant and anti-diabetic potential. It is also concluded that the methanol extract of the plant showed the maximum effect against inflammation induced by carrageenan in rat paw oedema as compared with n-hexane and chloroform extracts.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Abbas A,Hassan SS,Sharif A,Ahmed S

doi

10.1080/14786419.2018.1490905

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

575-579

issue

4

eissn

1478-6419

issn

1478-6427

journal_volume

34

pub_type

杂志文章
  • Phenanthrene and dihydrophenanthrene derivatives from Dioscorea communis with anticholinesterase, and antioxidant activities.

    abstract::Five phenanthrene and two dihydrophenanthrene derivatives were isolated from the diethyl ether extract of fresh rhizomes of Dioscorea communis (L.), among them a phenanthrentriol 1 reported for the first time from Dioscoreaceae family and two dihydrophenanthrene derivatives 6 and 7 reported also for the first time fro...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1468328

    authors: Boudjada A,Touil A,Bensouici C,Bendif H,Rhouati S

    更新日期:2019-11-01 00:00:00

  • Effect of Agave americana L. on the human, and Aspergillus oryzae S2 α-amylase inhibitions.

    abstract::Among phenolic compounds, Agave americana L. extract contained puerarin (38.4%) and p-coumaric acid (12.29%) (pCa). From the Lineweaver-Burk plots, pCa and puerarin demonstrated a competitive and a non competitive inhibitions towards human α-amylase activity, respectively. PCa exhibited a higher human inhibitory activ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1408094

    authors: Sahnoun M,Bejar S,Daoud L,Ayadi L,Brini F,Saibi W

    更新日期:2019-03-01 00:00:00

  • Turmerin, the antioxidant protein from turmeric (Curcuma longa) exhibits antihyperglycaemic effects.

    abstract::A wide range of proteinaceous inhibitors are present in plants to protect themselves from hydrolytic enzymes. In this study, turmerin, a water-soluble peptide in turmeric rhizomes, was evaluated for its inhibitory potential against glucosidase and its antioxidant (AO) capacity. Turmerin inhibited α-amylase and α-gluco...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.589386

    authors: Lekshmi PC,Arimboor R,Raghu KG,Menon AN

    更新日期:2012-01-01 00:00:00

  • LC-ESI-MS/MS profiling of alkaloids and antiproliferative activity of Pachypoduim lamerei drake leaves.

    abstract::In the present study, evaluation of the antiproliferative activity of Pachypodium lamerei Drake leaves (family Apocyaceae) against human breast cancer cell lines MDA-MB-231 was done for the total methanolic extract, crude alkaloidal mixture and ursolic acid using the MTT colorimetric assay. The methanolic extract show...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1556264

    authors: Mina SA,Mohamed SA,Melek FR,Abd El-Khalik SM

    更新日期:2020-05-01 00:00:00

  • Alkaloids from the fungus Lactarius subplinthogalus.

    abstract::A new alkaloid, namely laccarin A (1), along with four known alkaloids, laccarin (2), adenosine (3), indole-3-carboxaldehyde (4) and nicotinamide (5), was isolated from the fungus Lactarius subplinthogalus. The structure of laccarin A (1) was established mainly by spectroscopic methods. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410310001608073

    authors: Wang Y,Yang SP,Wu Y,Yue JM

    更新日期:2004-04-01 00:00:00

  • Betula pendula Roth leaves: gastroprotective effects of an HPLC-fingerprinted methanolic extract.

    abstract::In this study, a methanolic extract of Betula pendula leaves (BLE) was investigated for its gastroprotective effects against 90% ethanol-induced ulcer in rats. Oral pretreatment of rats with BLE (100, 200 and 400 mg kg(- 1)) significantly reduced the incidence of gastric lesions induced by ethanol administration as co...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.740036

    authors: Germanò MP,Cacciola F,Donato P,Dugo P,Certo G,D'Angelo V,Mondello L,Rapisarda A

    更新日期:2013-01-01 00:00:00

  • Polyacanthoside A, a new oleanane-type triterpenoid saponin with cytotoxic effects from the leaves of Acacia polyacantha (Fabaceae).

    abstract::The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1486312

    authors: Fotso W G,Na-Iya J,Mbaveng T A,Ango Yves P,Demirtas I,Kuete V,Samuel Y,Ngameni B,Efferth T,Ngadjui T B

    更新日期:2019-12-01 00:00:00

  • Two new homoisoflavones from Portulaca oleracea L. and their activities.

    abstract::Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated from Portulaca oleracea L., and the structures of them were determined by spectroscopy, including one-dimensional and two-d...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1815742

    authors: Duan Y,Ying Z,Zhang M,Ying X,Yang G

    更新日期:2020-09-03 00:00:00

  • One new flavonoid from Solanum rostratum.

    abstract::One new flavonoid, 5,7,8,4'-tetrahydroxy-3-methoxyflavone-8-O-β-d-xylopyranoside (2), along with other four known flavones (1, 3-5) were isolated from the aerial parts of Solanum rostratum. 8-hydroxyflavonoid was isolated from series Androceras for the first time. The structure of the new compound 2 was determined on ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1290621

    authors: Huang HJ,Ling TJ,Wang HM,Cao AC,Zhang CX,Wei SH

    更新日期:2017-08-01 00:00:00

  • Flavonostilbenes from Sophora alopecuroides L. as multidrug resistance associated protein 1 (MRP1) inhibitors.

    abstract::Flavonoids have always attracted much attention due to their reversal activity on multidrug resistance (MDR). Eight flavonoids isolated from traditional Chinese medicine Sophora alopecuroides L. were applied to test their effect on MDR associated protein 1 (MRP1) through the established predicting assay. Three flavono...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.930856

    authors: Ni K,Yang L,Wan C,Xia Y,Kong L

    更新日期:2014-01-01 00:00:00

  • Anthraquinones from Morinda officinalis roots enhance adipocyte differentiation in 3T3-L1 cells.

    abstract::To search for anti-diabetic and insulin-sensitising natural products, the effect on adipocyte differentiation was investigated by assessing fat accumulation in 3T3-L1 preadipocytes using Oil Red O staining. Fractionation and separation of n-hexane and CHCl₃ fractions of Morinda officinalis (Rubiaceae) using several ch...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.608676

    authors: Liu Q,Kim SB,Ahn JH,Hwang BY,Kim SY,Lee MK

    更新日期:2012-01-01 00:00:00

  • Determination of chemopreventive role of Foeniculum vulgare and Salvia officinalis infusion on trichloroacetic acid-induced increased serum marker enzymes lipid peroxidation and antioxidative defense systems in rats.

    abstract::Today's world is increasingly seeking ways to replace the synthetic drugs with the therapeutic power of natural products. This study was designed to investigate the protective effects of Foeniculum vulgare (FV) and Salvia officinalis (SO) waters infusions against carcinogen chemical trichloroacetic acid (TCA)-exposure...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701590426

    authors: Celik I,Isik I

    更新日期:2008-01-10 00:00:00

  • A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae).

    abstract::A phytochemical investigation of the MeOH extract of twigs and leaves of Tephrosia preussi was carried out to give a new kaempferol triglycoside, named tephrokaempferoside (1), together with five known compounds: tephrosin (2), betulinic acid (3), lupeol (4), β-sitosterol (5) and 3-O-β-d-glucopyranoside of β-sitostero...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1315720

    authors: Mba Nguekeu YM,Awouafack MD,Tane P,Nguedia Lando MR,Kodama T,Morita H

    更新日期:2017-11-01 00:00:00

  • Relevant principal component analysis applied to the characterisation of Portuguese heather honey.

    abstract::The main purpose of this study was the characterisation of 'Serra da Lousã' heather honey by using novel statistical methodology, relevant principal component analysis, in order to assess the correlations between production year, locality and composition. Herein, we also report its chemical composition in terms of sug...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701825004

    authors: Martins RC,Lopes VV,Valentão P,Carvalho JC,Isabel P,Amaral MT,Batista MT,Andrade PB,Silva BM

    更新日期:2008-01-01 00:00:00

  • SPME-GC-MS analysis of commercial henna samples (Lawsonia inermis L.).

    abstract::The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1055491

    authors: Mengoni T,Peregrina DV,Censi R,Cortese M,Ricciutelli M,Maggi F,Di Martino P

    更新日期:2016-01-01 00:00:00

  • Two new anthraquinone malonylglucosides from Polygonum cuspidatum.

    abstract::Two new anthraquinone malonylglucosides polygonins A and B were isolated from Polygonum cuspidatum along with seven known compounds. The structures of 1 and 2 were elucidated based on their spectroscopic data. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.578072

    authors: Zhang H,Zhang QW,Wang L,Zhang XQ,Ye WC,Wang YT

    更新日期:2012-01-01 00:00:00

  • Modulation of the 5-HT3A receptor current by desacylbaldrinal.

    abstract::The serotonin (5-hydroxytryptamine) type 3 receptor is an important target in the control of digestive dysfunction such as anorexia and bulimia, and 5-HT3 receptor antagonists are effective against eating disorder and the early-phase chemotherapy and radiotherapy evoked vomiting. Our previous research of Valeriana jat...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1662009

    authors: Wang LX,Chen HL,Yan HL,Tang F,Zhang H,Li HX,Ye Q,Peng C,Tan YZ

    更新日期:2019-09-10 00:00:00

  • Anti-inflammatory monoterpene esters from the stems of Illigera aromatica.

    abstract::Two new monoterpene esters illigerates F and G (1 and 2) together with 5 know compounds illigerate A (3), illigerate C (4), actinodaphnine (5), N-methylactinodaphnine(6) and N-methyllaurotetanine(7) were isolated from Illigera aromatica S. Z. Huang et S. L. Mo. Their structures were identified by extensive NMR data an...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1614574

    authors: Pu XY,Tian K,Sun JX,Wang W,Liu HC,Yang J,Jiang MY,Huang XZ

    更新日期:2019-05-28 00:00:00

  • Chemical composition and antimicrobial activities of Perovskia artemisioides Boiss. essential oil.

    abstract::The Perovskia artemisioides Boiss. essential oil obtained by hydrodistillation method of flowers growing wild in the north of Iran. The study led to the identification of 29 compositions by a combination of HP-5 GC-FID and GC-MS analytical techniques. The constituents were identified in P. artemisioides essential oil ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1101694

    authors: Hafez Ghoran S,Azadi B,Hussain H

    更新日期:2016-09-01 00:00:00

  • Seed oils from non-conventional sources in north-east India: potential feedstock for production of biodiesel.

    abstract::A total of nine oilseeds with more than 15 wt% oil have been investigated for evaluating them as feedstock for biodiesel industries. Fatty acid profiles of all the nine oil samples have been determined by GC-MS analysis. The saponification numbers, gross heats of combustion of the oils and those of corresponding fatty...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.881361

    authors: Barua P,Dutta K,Basumatary S,Deka DC,Deka DC

    更新日期:2014-01-01 00:00:00

  • Six new metabolites produced by Colletotrichum aotearoa 09F0161, an endophytic fungus isolated from Bredia oldhamii.

    abstract::Six new compounds, colletobredins A-D (1-4) and colletomelleins A and B (5 and 6), along with 12 previously identified compounds, were isolated from the culture broth of Colletotrichum aotearoa BCRC 09F0161, a fungal endophyte residing in the leaves of an endemic Formosan plant Bredia oldhamii Hook. f. (Melastomatacea...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1054285

    authors: Hsiao Y,Cheng MJ,Chang HS,Wu MD,Hsieh SY,Liu TW,Lin CH,Yuan GF,Chen IS

    更新日期:2016-01-01 00:00:00

  • Volatile composition, antibacterial and antioxidant activities of artemisia tournefortiana Reichb. from Kashmir, India.

    abstract::The importance of the present study is to find out the phytochemical profile of essential oil (EO) of Artemisia tournefortiana Reichb. and its biological evaluation. Nineteen volatile constituents were identified from EO representing 93.47% of total oil composition. Oxygenated monoterpenes (54.46%) were found to be do...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1613990

    authors: Qadir M,Maurya AK,Agnihotri VK,Shah WA

    更新日期:2021-01-01 00:00:00

  • Phytochemical analysis and evaluation of antioxidant and antimycobacterial activity of Colletia paradoxa from Brazil.

    abstract::Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1598987

    authors: Bastos Záchia NR,Piana M,Dos Santos Siqueira F,da Silva Jesus R,Athayde ML,Essi L,de Campos MMA

    更新日期:2019-04-16 00:00:00

  • An unreported bis-abeo cembrane-type diterpenoid with antioxidative and anti-lipoxygenase activities from the muricid gastropod mollusc Chicoreus ramosus.

    abstract::The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was characterized as (3E, 6E, 10E)-8a-butoxy-17(15→14), 20(12→11)-bis-abeo-ce...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1527833

    authors: Chakraborty K,Salas S,Joy M

    更新日期:2020-06-01 00:00:00

  • A new androstanoid metabolite from a soil fungus Curvularia borreriae strain HS-FG-237.

    abstract::A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cel...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1272115

    authors: Liu LF,Zhang H,Qi H,Wang XM,Wang JD,Tan GS

    更新日期:2017-05-01 00:00:00

  • Identification and structural characterisation of triterpene saponins from the root of Ardisia mamillata Hance by HPLC-ESI-QTOF-MS/MS.

    abstract::Triterpene saponins in medicinal plants attract scientific attentions for their structural diversity and significant bioactivities. In this work, a high-performance liquid chromatography coupled to electrospray ionisation and quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS/MS) method is used to rapidly s...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1367787

    authors: Zhang EF,Ling Y,Yin Z,Zhang Q

    更新日期:2018-04-01 00:00:00

  • Antibacterial effects of Brazilian and Bulgarian propolis and synergistic effects with antibiotics acting on the bacterial DNA and folic acid.

    abstract::Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786411003754355

    authors: Orsi RO,Fernandes A Jr,Bankova V,Sforcin JM

    更新日期:2012-01-01 00:00:00

  • UHPLC-MS/MS phenolic profiling and in vitro antioxidant activities of Inula graveolens (L.) Desf.

    abstract::Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1350673

    authors: Silinsin M,Bursal E

    更新日期:2018-06-01 00:00:00

  • Plumieride exerts anxiolytic-like effect mediated by GABAergic and monoaminergic systems.

    abstract::Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1737052

    authors: Dalmagro AP,Camargo A,Zimath PL,Bonomini TJ,Zeni ALB,Malheiros A,de Souza MM

    更新日期:2020-03-11 00:00:00

  • Effect of myricetin on deoxycorticosterone acetate (DOCA)-salt-hypertensive rats.

    abstract::Chronic administration of myricetin (100 and 300 mg kg⁻¹, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension and oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes and reversed th...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903335190

    authors: Borde P,Mohan M,Kasture S

    更新日期:2011-09-01 00:00:00