Purification and characterization of two grandiuvarones from Desmos chinensis leaves and their antimicrobial activities.

abstract：:The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against...

journal_title：Natural product research

authors： Ushimaru PI,Barbosa LN,Fernandes AA,Di Stasi LC,Fernandes A Jr

更新日期：2012-01-01 00:00:00

abstract：:Chemical investigation of the root bark of Morus alba led to the isolation of a new flavone, dioxycudraflavone A (1) and a new 2-arylbenzofuran, 5-hydroxyethyl moracin M (2), together with seven known compounds namely sanggenon V (3), morusin (4), morusignin L (5), licoflavone C (6), moracin C (7), alfafuran (8) and m...

journal_title：Natural product research

authors： Li M,Wu X,Wang X,Shen T,Ren D

更新日期：2018-01-01 00:00:00

abstract：:Fourteen wild strains of Staphylococcus aureus positive for gene sea were tested for enterotoxins production and the minimum inhibitory concentration of Leptospermum scoparium, Origanum majorana, Origanum vulgare, Satureja montana and Thymus vulgaris essential oils (EOs) were determined. After this trial, bacteria str...

journal_title：Natural product research

authors： Turchi B,Mancini S,Pistelli L,Najar B,Cerri D,Fratini F

更新日期：2018-03-01 00:00:00

abstract：:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6'-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures w...

journal_title：Natural product research

authors： Pang X,Wang LM,Zhang YC,Kang LP,Yu HS,Fan GW,Han LF

更新日期：2019-12-01 00:00:00

abstract：:Oleiferoside B is a triterpenoid monomer compound, mainly isolated from roots of Camellia oleifera Abel, the underlying mechanism of its antitumour is not clear. In the present study, oleiferoside B potently inhibited SMMC-7721 and MCF-7 cells proliferation and cause cells apoptosis. In addition, it activated an autop...

journal_title：Natural product research

authors： Feng S,Zha Z,Wang Z,Yang P,Wu J,Li X,Xu Q,Liu Y

更新日期：2020-03-18 00:00:00

abstract：:The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl co...

journal_title：Natural product research

authors： Tan BX,Yang L,Huang YY,Chen YY,Peng GT,Yu S,Wu YN,Luo HB,He XX

更新日期：2017-12-01 00:00:00

abstract：:A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of th...

journal_title：Natural product research

authors： Rahmani M,Leng KW,Ismail HB,Hin TY,Sukari MA,Ali AM,Kulip J

更新日期：2004-02-01 00:00:00

abstract：:Phytochemical investigation of the methanolic extract of Vangueria agrestis aerial parts led to the isolation and characterization of four monoterpene rhamnosides, two ursane saponins, and six flavonoid glycosides. Of these constituents, are three undescribed monoterpene glycosides, vangagrestosides A-C. The reported ...

journal_title：Natural product research

authors： Osman AG,Fantoukh O,Ali Z,Raman V,Ibrahim MA,Khan IA

更新日期：2020-02-24 00:00:00

abstract：:Chronic neuroinflammation is a key component of many neurodegenerative disorders. Chronic activation of this process produces pro-inflammatory cytokines, prostaglandins and reactive oxygen species that induce brain injury and neuronal dysfunction. Agave species contain saponins, compounds with anti-inflammatory activi...

journal_title：Natural product research

authors： Herrera-Ruiz M,Jiménez-Ferrer E,Tortoriello J,Zamilpa A,Alegría-Herrera E,Jiménez-Aparicio AR,Arenas-Ocampo ML,Martínez-Duncker I,Monterrosas-Brisson N

更新日期：2019-05-14 00:00:00

abstract：:An HPLC/DAD/ESI-MSn method was established to characterise flavonoids in the seeds of Sophora alopecuroides L. All the flavonoids exhibited abundant [M-H]- ions, which triggered data-dependent multistage mass spectrometry fragmentations. Characteristic UV spectra were used to confirm flavonoid subtypes. In total, 22 f...

journal_title：Natural product research

authors： Yang WZ,Ye G,Meng AH,Sabir G,Qiao X,Guo DA,Ye M

更新日期：2013-03-01 00:00:00

abstract：:A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

journal_title：Natural product research

authors： Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

更新日期：2005-10-01 00:00:00

abstract：:A new alkynol, platycodynol (1), identified as 2, 3, 9, 13, 14-pentahydroxy-4, 6-tetradecadiyne, along with six known compounds (2-7) were obtained from Platycodins folium for the first time. Their structures were elucidated with infrared (IR), ultraviolet (UV), 1D and 2D nuclear magnetic resonance (NMR) spectroscopic...

journal_title：Natural product research

authors： Wang C,Dong Q,Wu F,Li Z,Li P,Liu J,Wang F

更新日期：2020-01-17 00:00:00

abstract：:A phytochemical reinvestigation of the whole plant of Euphorbia segetalis yielded five tetracyclic triterpenes: 3beta-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3beta,24-diol (2), cycloart-23-ene-3beta,25-diol (3), lanosta-7,9(11),24-trien-3beta-ol (4) and lanosta-7,9(11),24(31)-trien-3beta-ol (5). beta-acetox...

journal_title：Natural product research

authors： Madureira AM,Ascenso JR,Valdeira L,Duarte A,Frade JP,Freitas G,Ferreira MJ

更新日期：2003-10-01 00:00:00

abstract：:Five flavonol glycosides characterised as kaempferide 3-O-(2'',3''-diacetylglucoside), kaempferide 3-O-(2''-O-galloylrhamnoside), kaempferide 3-O-(2''-O-galloylrutinoside)-7-O-alpha-rhamnoside, kaempferol 3-O-[beta-glucosyl-(1 --> 2)]-[alpha-rhamnosyl-(1 --> 6)]-beta-glucoside-7-O-alpha-rhamnoside and kaempferol 3-O-[...

journal_title：Natural product research

authors： Manguro LO,Lemmen P

更新日期：2007-01-01 00:00:00

abstract：:Synsepalum dulcifificum is an evergreen shrub native of tropical West Africa. It is very effective against a variety of diseases. However, the phytochemical investigation on this plant is limited till now. In our current study, seventeen compounds were isolated and identified from the ethyl acetate extract of the leav...

journal_title：Natural product research

authors： Wang J,Shao S,Huang R,Wu S

更新日期：2020-10-09 00:00:00

abstract：:The ability of the endophytic fungus Umbelopsis dimorpha SWUKD3.1410 to transform the triterpene nigranoic acid (3, 4-secocycloarta-4(28), 24-(Z)-diene-3, 26-dioic acid; 1) was investigated. Co-culture of nigranoic acid with U. dimorpha SWUKD3.1410 yielded six major products, including a new triterpene (2) and 5 known...

journal_title：Natural product research

authors： Wang L,Qin D,Zhang K,Huang Q,Liu S,Han MJ,Dong JY

更新日期：2017-06-01 00:00:00

abstract：:The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison...

journal_title：Natural product research

authors： Fotso W G,Na-Iya J,Mbaveng T A,Ango Yves P,Demirtas I,Kuete V,Samuel Y,Ngameni B,Efferth T,Ngadjui T B

更新日期：2019-12-01 00:00:00

abstract：:Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin which is used extensively by Ayurvedic physicians to treat various ailments. However, most of the studies on C. wightii have been limited to its gum resin. Comprehensive metabolic profiling of leaves, stem and gum resin sam...

journal_title：Natural product research

authors： Bhatia A,Tripathi T,Singh S,Bisht H,Behl HM,Roy R,Sidhu OP

更新日期：2019-01-01 00:00:00

abstract：:The optimisation of nutritional requirements for dopamine (DA) synthesis by calcium alginate-entrapped mutant variant of Aspergillus oryzae EMS-6 using submerged fermentation technique was investigated. A total of 13 strains were isolated from soil. Isolate I-2 was selected as a better producer of DA and improved by e...

journal_title：Natural product research

authors： Ali S,Nawaz W

更新日期：2017-02-01 00:00:00

abstract：:Globe artichoke has been long considered a nutraceutical food for its valuable content of bioactive compounds. However, beside a well-known polyphenol profile, poor information is available about its metabolite and mineral composition. The aim of this study was to investigate edible parts of Sicilian artichokes, 'Spin...

journal_title：Natural product research

authors： Albergamo A,Rotondo A,Salvo A,Pellizzeri V,Bua DG,Maggio A,Cicero N,Dugo G

更新日期：2017-05-01 00:00:00

abstract：:A screening of Chinese medicinal herbs and wild plants for agrochemicals was carried out; the essential oil of Glycosmis lucida leaves was found to possess significant repellent activity against Tribolium castaneum and Liposcelis bostrychophila. It was found that the main components included elixene (19.81%), spathule...

journal_title：Natural product research

authors： Guo SS,Zhang WJ,Yang K,Liang JY,You CX,Wang CF,Li YP,Geng ZF,Deng ZW,Du SS

更新日期：2017-05-01 00:00:00

abstract：:Here is reported the anti Leishmania infantum activity of 48 hexane, CH2Cl2 and MeOH extracts from 16 macroalgae collected on the Iberian Coast. Seven hexane and CH2Cl2Cystoseira baccata, Cystoseira barbata, Cystoseira tamariscifolia, Cystoseira usneoides, Dictyota spiralis and Plocamium cartilagineum extracts were ac...

journal_title：Natural product research

authors： Bruno de Sousa C,Lago JHG,Macridachis J,Oliveira M,Brito L,Vizetto-Duarte C,Florindo C,Hendrickx S,Maes L,Morais T,Uemi M,Neto L,Dionísio L,Cortes S,Barreira L,Custódio L,Alberício F,Campino L,Varela J

更新日期：2019-06-01 00:00:00

abstract：:This study showed for the first time the antioxidant and hypoglycaemic properties of the methanol, n-hexane and ethyl acetate extracts from Senecio stabianus Lacaita, a plant that belongs to the Asteraceae family. The antioxidant activities were carried out using two different in vitro assays, namely 2,2-diphenyl-1-pi...

journal_title：Natural product research

authors： Tundis R,Menichini F,Loizzo MR,Bonesi M,Solimene U,Menichini F

更新日期：2012-01-01 00:00:00

abstract：:Antimicrobial potential of medicinal plants have been explored extensively these days. This study was carried out to evaluate the antibacterial potential from aerial parts of plant, called 'Annona senegalensis' and its constituents. Bioassay guided fractionation led to the isolation of four metabolites, (+)-catechin (...

journal_title：Natural product research

authors： Lall N,Kishore N,Bodiba D,More G,Tshikalange E,Kikuchi H,Oshima Y

更新日期：2017-08-01 00:00:00

abstract：:In this study the antioxidant and cytotoxicity activity of the Adonidia merrillii fruits were investigated using different solvent polarities (methanol, ethyl acetate and water). The results showed that the total phenolic and flavonoid contents of the methanolic extract was higher compare with other extract with respe...

journal_title：Natural product research

authors： Vafaei A,Bin Mohamad J,Karimi E

更新日期：2019-09-01 00:00:00

abstract：:A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...

journal_title：Natural product research

authors： Xianjin S,Sha S,Qi M,Zhang Z,Yang Y,Wu H,Li L,Wang W,Huang A

更新日期：2018-07-01 00:00:00

abstract：:One new havanensin-type limonoid (1) named trisinlin A with two known compounds (4E,8E)-2-[2'-hydroxyhexadecanoyl amino]-4,8-octadecadiene-1,3-diol (2), 9-octadecenoic acid-2',3'-dihydroxypropyl ester (3) were isolated from the roots of Trichilia sinensis. The structure of the new compound was unambiguously determined...

journal_title：Natural product research

authors： Liu SB,Chen HQ,Feng G,Guo ZK,Cai CH,Wang J,Mei WL,Dai HF

更新日期：2018-12-01 00:00:00

abstract：:This study describes the seasonal composition and the antibacterial, antioxidant and anticholinesterase activity of the essential oil from Eugenia brasiliensis leaves. Analysis by using GC allowed the identification of 40 compounds. It was observed that the monoterpenes varied more (42%) than the sesquiterpenes (14%),...

journal_title：Natural product research

authors： Siebert DA,Tenfen A,Yamanaka CN,de Cordova CM,Scharf DR,Simionatto EL,Alberton MD

更新日期：2015-02-01 00:00:00

abstract：:This study reports for the first time in the chemical composition of acetone, ether, ethyl acetate and dichloromethane extracts of Hypogymnia tubulosa determined by HPLC-UV, GC-FID and GC-MS as well as effect of H. tubulosa acetone extract on micronucleus distribution on human lymphocytes and on cholinesterase activit...

journal_title：Natural product research

authors： Stojanović G,Zlatanović I,Zrnzević I,Stanković M,Stankov Jovanović V,Zlatković B

更新日期：2018-11-01 00:00:00

abstract：:Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...

journal_title：Natural product research

authors： Turner DN,Just J,Dasari R,Smith JA,Bissember AC,Kornienko A,Rogelj S

更新日期：2019-04-28 00:00:00