Flavonostilbenes from Sophora alopecuroides L. as multidrug resistance associated protein 1 (MRP1) inhibitors.

abstract：:One new briarane-type diterpenoid, dichotellide V (1), along with four known analogues, gemmacolide N (2), dichotellide J (3), junceelin A (4) and junceellolide A (5), was isolated from the South China Sea gorgonian Dichotella gemmacea. All of the isolated compounds (1-5) were established by comprehensive analysis of ...

journal_title：Natural product research

authors： Sun JF,Yang B,Zhou XF,Yang XW,Wang L,Liu Y

更新日期：2015-01-01 00:00:00

abstract：:The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...

journal_title：Natural product research

authors： Mengoni T,Peregrina DV,Censi R,Cortese M,Ricciutelli M,Maggi F,Di Martino P

更新日期：2016-01-01 00:00:00

abstract：:A new indole diterpene, named penicindopene A (1), together with seven known compounds (2 - 8), was isolated from the deep-sea fungus Penicillium sp. YPCMAC1. The structure of penicindopene A was elucidated by extensive spectroscopic analyses (1 D and 2 D NMR, and HRESIMS data), in addition to the ECD calculations for...

journal_title：Natural product research

authors： Liu L,Xu W,Li S,Chen M,Cheng Y,Yuan W,Cheng Z,Li Q

更新日期：2019-10-01 00:00:00

abstract：:Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D a...

journal_title：Natural product research

authors： Saputri RD,Tjahjandarie TS,Tanjung M

更新日期：2019-07-22 00:00:00

abstract：:An activity-guided isolation and purification process was used to identify the l,l-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging components of the food plant (Terminalia arjuna) of Antheraea mylitta. Dry leaves of T. arjuna were extracted with different solvents and tested for their antioxidant activity aga...

journal_title：Natural product research

authors： Singh PP,Chauhan SM

更新日期：2014-01-01 00:00:00

abstract：:A new cyclopeptide alkaloid, sativanine-M (1), together with known alkaloid nummularine-P have been isolated from the stem bark of Zizyphus sativa and identified by spectral analysis. ...

journal_title：Natural product research

authors： Pandey MB,Singh AK,Singh VP,Pandey VB

更新日期：2008-02-15 00:00:00

abstract：:Mangrove plants are endowed with various biologically active compounds which have potent antibacterial and antioxidant properties. In present study, a bioactivity-guided fractionation for antibacterial and antioxidant active metabolites from the twigs of Avicennia officinalis collected from Kuala Selangor Nature Park,...

journal_title：Natural product research

authors： Assaw S,Mohd Amir MIH,Khaw TT,Bakar K,Mohd Radzi SA,Mazlan NW

更新日期：2020-08-01 00:00:00

abstract：:The chemical composition and antioxidant activities of the essential oil from Nandina domestica fruits were studied for the first time. Twenty-two compounds, representing 82.79% of the oil, were identified from the oil. The major compounds were 3-hexen-1-ol (12.9%), linalool (12.3%), 2-methoxy-4-vinylphenol (9.9%), ol...

journal_title：Natural product research

authors： Bi SF,Zhu GQ,Wu J,Li ZK,Lv YZ,Fang L

更新日期：2016-01-01 00:00:00

abstract：:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...

journal_title：Natural product research

authors： Benkendorff K,Pillai R,Bremner JB

更新日期：2004-10-01 00:00:00

abstract：:Leishmaniasis is caused by parasites of the genus Leishmania. Recent reports about leishmaniasis show a few number of drugs available, indicating the necessity of new drugs. In this study, the ethanol extract and fractions of Pityrogramma calomelanos (L.) link. (Pteridaceae) were assayed to verify the cytotoxicity and...

journal_title：Natural product research

authors： Souza TM,Morais-Braga MF,Saraiva AÁ,Rolón M,Vega C,de Arias AR,Costa JG,Menezes IR,Coutinho HD

更新日期：2013-01-01 00:00:00

abstract：:Further studies on Plectranthus sp. (Lamiaceae) led to the isolation of terpenes and phenol esters from Plectranthus strigosus Benth. ent-16-Kauren-19-ol (1), ent-16-kauren-19-oic acid (2), xylopic acid (3), xylopinic acid (4), hinokiol (5), 4 beta,6 beta-dihydroxy-1 alpha,5 beta(H)-guai-9-ene (6) 4 beta,6 beta-dihydr...

journal_title：Natural product research

authors： Gaspar-Marques C,Simões MF,Valdeira ML,Rodríguez B

更新日期：2008-01-20 00:00:00

abstract：:This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal...

journal_title：Natural product research

authors： Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

更新日期：2008-02-15 00:00:00

abstract：:The present study was undertaken to investigate the antiproliferative action of isolated M1 (6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) from Mucuna pruriens seeds using human hepatic carcinoma cell line (Huh-7 cells). Initially, docking studies was performed to find out the binding affinities of M...

journal_title：Natural product research

authors： Kumar P,Rawat A,Keshari AK,Singh AK,Maity S,De A,Samanta A,Saha S

更新日期：2016-01-01 00:00:00

abstract：:Two new triterpene saponins, albidosides H (1) and I (2), along with the three known saponins were isolated from the barks of Acacia albida. Their structures were elucidated on the basis of extensive 1D- and 2D-NMR studies and mass spectrometry. Albidosides H (1) and I (2) were assayed for their cytotoxicity against H...

journal_title：Natural product research

authors： Tchoukoua A,Kuiate Tabopda T,Konga Simo I,Uesugi S,Ohno M,Kimura KI,Kwon E,Momma H,Shiono Y,Ngadjui BT

更新日期：2018-04-01 00:00:00

abstract：:Crambe orientalis L. (Brassicaceae), a perennial herb, is indigenous to Iran. The essential oils of flowering tops and leaves of the plant were evaluated by GC-MS. Our results showed that while 2-methyl-5-hexenitrile (19.5%) and benzyl cyanide (16.9%) were the major components of flowering tops oil, the oil of the lea...

journal_title：Natural product research

authors： Razavi SM,Nejad-Ebrahimi S

更新日期：2009-01-01 00:00:00

abstract：:In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...

journal_title：Natural product research

authors： Rauf A,Uddin G,Khan H,Raza M,Zafar M,Tokuda H

更新日期：2016-01-01 00:00:00

abstract：:Lappaconitine is an important alkaloid of the aconite family and its biological activity is closely related to its structure. Through an X-ray structure analysis of hydrated lappaconitine hydrobromide, which was synthesised by us through a new method, the absolute configuration of lappaconitine was determined: monocli...

journal_title：Natural product research

authors： Sun W,Wang Y,Zhang J,Yu K

更新日期：2009-01-01 00:00:00

abstract：:The methanolic extract of the Tanacetum gracile afforded the isolation of new sesquiterpene lactone, named gracilone (1) along with four known compounds as 14α-taraxeran-3-one (2), 14α-taraxeran-3-ol (3), apigenin (4) and β-sitosterol (5). The structure of compound 1 was elucidated on the basis of 1D, 2D NMR and MS sp...

journal_title：Natural product research

authors： Bhat G,Masood A,Ganai BA,Hamza B,Ganie S,Shafi T,Idris A,Shawl AS,Tantry MA

更新日期：2016-10-01 00:00:00

abstract：:Two new flavonoids, 3, 3', 4' -Trihydroxy- 6, 7, 8 -trimethoxy flavone (1) and 3-Hydroxy-6, 7, 8, 3', 4'-pentamethoxy flavone (2) have been isolated from the methanol extract of Blumea eriantha DC. The structures of these compounds were determined on the basis of spectroscopic techniques such as IR, MS, 1 D, and 2 D N...

journal_title：Natural product research

authors： Tambewagh UU,Javir GR,Joshi KS,Rojatkar SR

更新日期：2019-10-03 00:00:00

abstract：:Six sesquiterpenoids and four lignans (1-10) were isolated from the n-BuOH extract of the rhizomes of Atractylodes lancea. Among them, the new sesquiterpenoid glycoside named (4 R, 5S, 7R)-hinesolone-11-O-β-ᴅ-glucopyranoside (1), along with three known compounds (2-4) were first obtained from this genus. All the isola...

journal_title：Natural product research

authors： Long L,Wang L,Qi S,Yang Y,Gao H

更新日期：2020-04-01 00:00:00

abstract：:A new propanamide analogue (1), along with one known alkaloid (2) and four known diketopiperazines (3-6), was isolated from a cultured broth of the actinomycete Streptomyces sp. Q24 that was obtained from a sample of mangrove soil. The structures of these isolates were characterised as 3-acetylamino-N-2-thienyl-propan...

journal_title：Natural product research

authors： Ye X,Chai W,Lian XY,Zhang Z

更新日期：2017-06-01 00:00:00

abstract：:A phytochemical investigation on Lagotis brevituba led to the isolation and characterisation of 11 phenolic compounds: p-hydroxy-benzoic acid 1, methyl 3,4-dihydroxybenzoate 2, vanillic acid 3, protocatechuic acid 4, caffeic acid 5, glucose ester of (E)-ferulic acid 6, p-coumaric acid 7, vanillin 8, diosmetin-7-O-β-d-...

journal_title：Natural product research

authors： Yuan X,Wen H,Cui Y,Fan M,Liu Z,Mei L,Shao Y,Wang Y,Tao Y

更新日期：2017-02-01 00:00:00

abstract：:Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their ...

journal_title：Natural product research

authors： Li W,Tang GH,Chen L,Tang YQ,Xu YK,Liu B,Yin S

更新日期：2018-07-01 00:00:00

abstract：:Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were ev...

journal_title：Natural product research

authors： Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SH

更新日期：2019-04-10 00:00:00

abstract：:Two new chromones, spororrminone A (1, (S)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2-epi-spororrminone A (2, (R)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sp...

journal_title：Natural product research

authors： Huang MJ,Li YJ,Tang J,Chen GD,Hu D,Xu W,Guo LD,Yao XS,Gao H

更新日期：2020-11-01 00:00:00

abstract：:Fusarium graminearum Schw. is associated with diseases in seeds and seedlings, mainly in maize, and causes damage to crops and food production. We determined the chemical compositions of essential oils from Pogostemon cablin (Blanco) Benth and Baccharis dracunculifolia DC., and evaluated their antioxidant and antifung...

journal_title：Natural product research

authors： Luchesi LA,Paulus D,Busso C,Frata MT,Oliveira JB

更新日期：2020-08-06 00:00:00

abstract：:A new sesquiterpeniod, 6alpha, 7alpha, 10alpha-trihydroxyisoducane (1), together with two known sesquiterpenoids, oplodiol (2) and oplopanone (3), were isolated from the chloroform extract of the rhizomes of Homalomena occulta. Their structures were elucidated by 1D and 2D NMR spectral interpretation. ...

journal_title：Natural product research

authors： Hu YM,Yang ZL,Wang H,Ye WC

更新日期：2009-01-01 00:00:00

abstract：:This study investigated the pharmacokinetics of hesperidin (HP), ferulic acid (FA) and p-coumaric acid (CA) in rat plasma after oral administration of Portulaca oleracea L. extract (POE). The plasma concentrations were determined by HPLC with vitexin-2″-O-rhamnoside (VR) as internal standard. The calibration curves we...

journal_title：Natural product research

authors： Cheng Z,Wang D,Zhang W,Du Y,Wang Y,Zhai Y,Ying X,Kang T

更新日期：2012-01-01 00:00:00

abstract：:Two new C13-norsesquiterpenes claulanterpene A (1) and B (2), together with two known sesquiterpenes (3-4), were isolated from methanol extract of the stem and leaf of Clausena lansium collected from Qingyuan county, Guangdong Province, China. Their structures were elucidated on the base of extensive spectroscopic ana...

journal_title：Natural product research

authors： Liu XY,Fu XX,Li YY,Xiong ZH,Li BT,Peng WW

更新日期：2020-03-25 00:00:00

abstract：:Six compounds, benzyl 3-O-β-D-glucopyranosyl-7-hydroxybenzoate (1), spathulenol (2), 1,7,8-trihydroxy-2-naphtaldehyde (3), quercetin (4), astragalin (5) and 2-methoxy-4-(2-propenyl)phenyl β-D-glucoside (6), were isolated from the leaves of Melia azedarach L. The structure elucidation of compound 1 was discussed in det...

journal_title：Natural product research

authors： Zeng J,Ma RJ,Wang L,Zhang SN,Song HZ,Yang Y,Tan QG

更新日期：2019-10-01 00:00:00