Abstract:
:Six compounds, benzyl 3-O-β-D-glucopyranosyl-7-hydroxybenzoate (1), spathulenol (2), 1,7,8-trihydroxy-2-naphtaldehyde (3), quercetin (4), astragalin (5) and 2-methoxy-4-(2-propenyl)phenyl β-D-glucoside (6), were isolated from the leaves of Melia azedarach L. The structure elucidation of compound 1 was discussed in detail based on its 2D-NMR data. Compound 1 showed weak cytotoxicity against the cell lines of T-24, NCI-H460, HepG2, SMMC-7721, CNE, MDA-MB-231 and B16F10 with the inhibition rates from 10.01% to 34.05% at the concentration of 80 μM.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Zeng J,Ma RJ,Wang L,Zhang SN,Song HZ,Yang Y,Tan QGdoi
10.1080/14786419.2018.1501690subject
Has Abstractpub_date
2019-10-01 00:00:00pages
2860-2863issue
19eissn
1478-6419issn
1478-6427journal_volume
33pub_type
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