Screening of medicinal plants traditionally used in Peruvian Amazon for in vitro antioxidant and anticancer potential.

abstract：:A new resin glycoside, named calysolin XVIII (1), was isolated from the leaves, stems and roots of Calystegia soldanella Roem. et Schult. (Convolvulaceae). The structure of 1 was defined as 11S-jalapinolic acid 11-O-β-d-glucopyranosyl-(1 → 3)-O-(2-O-2S-methylbutyryl,4-O-3-hydroxy-2-methylenebutyryl)-α-l-rhamnopyranosy...

journal_title：Natural product research

authors： Ono M,Kanemaru Y,Yasuda S,Okawa M,Kinjo J,Miyashita H,Yokomizo K,Yoshimitsu H,Nohara T

更新日期：2017-11-01 00:00:00

abstract：:The emphasis of the present study is to evaluate a natural product and the potential microbicide activity using a dual chamber infection method. Malva sylvestris extracts and fractions were screened for anti-HIV activity by measuring the virus-antibody neutralization. Plant extracts with strong antiviral activity work...

journal_title：Natural product research

authors： Benso B,Rosalen PL,Pasetto S,Marquezin MCS,Freitas-Blanco V,Murata RM

更新日期：2019-08-20 00:00:00

abstract：:A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representin...

journal_title：Natural product research

authors： Rajkapoor B,Murugesh N,Rama Krishna D

更新日期：2009-01-01 00:00:00

abstract：:The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...

journal_title：Natural product research

authors： da Silva Landim EMBM,Ruiz ALTG,de Carvalho JE,Pomini AM,Pastorini LH,Oliveira Santin SM

更新日期：2019-08-12 00:00:00

abstract：:Three new (1-3) and 17 known (4-20) iridoid and secoiridoid glycosides were isolated from a methanol extract of the rhizomes and roots of Gentiana scabra. Their chemical structures were elucidated from 1D and 2D NMR, IR absorption, and HR-ESI-MS spectra, as well as comparisons of these data with reported values. The e...

journal_title：Natural product research

authors： Li W,Zhou W,Kim S,Koo JE,Kim Y,Koh YS,Shim SH,Ma JY,Kim YH

更新日期：2015-01-01 00:00:00

abstract：:Resinous exudate obtained from the aerial parts of Adesmia boronioides Hook.f. were evaluated to determine anti-phytopathogenic effects. Briefly, resinous exudate was obtained by dipping fresh plant material in dichloromethane; chemical composition was determined by GC-MS; and minimum inhibitory concentration (MIC) an...

journal_title：Natural product research

authors： Montenegro I,Valenzuela M,Zamorano N,Santander R,Baez C,Madrid A

更新日期：2019-08-06 00:00:00

abstract：:Ten compounds (1-10) were purified from the extract of lichens C. faveomaculata, and among these one new triterpenoid, cryptothecin A (1) was characterized through mass spectrometric and 2D NMR spectroscopic analyses. Some of the isolated compounds were assessed for their antimicrobial (1, 6, and 8) and cytotoxic acti...

journal_title：Natural product research

authors： Ngoc Tuan N,Kuo PC,Trung Hieu T,Tuong Vi LN,Tong Hung Q,Dunge LT,Duy Trinh N,Quang Trung N,Cuu Khoa N,Viet Hai H,Thang TD

更新日期：2019-08-02 00:00:00

abstract：:The essential oil of the 'resurrection plant' Myrothamnus moschatus (Baillon) Niedenzu endemic to Madagascar, where it is used in traditional medicine, was investigated for the first time for some biological activities. GC-FID and GC-MS analyses revealed trans-pinocarveol (35.6%), pinocarvone (20.0%), β-selinene (8.5%...

journal_title：Natural product research

authors： Nicoletti M,Maggi F,Papa F,Vittori S,Quassinti L,Bramucci M,Lupidi G,Petrelli D,Vitali LA,Ralaibia E,Rasoanaivo P

更新日期：2012-01-01 00:00:00

abstract：:This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...

journal_title：Natural product research

authors： Sadeghi Z,Alizadeh Z,Khorrami F,Norouzi S,Moridi Farimani M

更新日期：2020-08-26 00:00:00

abstract：:This work is an attempt to explore the anti-spermatogenic activity of Pistia stratiotes and to investigate it as a male contraceptive. The prepared extracts were screened for the presence of alkaloids, glycosides, steroids, flavonoids, saponin and phenolic compounds. To assess the anti-spermatogenic activity, mice wer...

journal_title：Natural product research

authors： Singh K,Dubey BK,Tripathi AC,Singh AP,Saraf SK

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to explore the extract/fractions and compounds of Diospyros lotus against various Gram-positive and Gram-negative bacteria strain. The results showed marked susceptibility of extract and its fractions against test pathogens. Among them, chloroform fraction was most dominant and effective agai...

journal_title：Natural product research

authors： Rauf A,Uddin G,Khan H,Arfan M,Siddiqui BS

更新日期：2016-01-01 00:00:00

abstract：:Two new flavans, named (2S)-2',4'-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2'-hydroxy-4',7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2...

journal_title：Natural product research

authors： Tang BQ,Huang SS,Liang YE,Sun JB,Ma Y,Zeng B,Lee SM,Lu JL

更新日期：2017-07-01 00:00:00

abstract：:This work reports on the composition and bionutritional value of organic virgin olive oil from the Nocellara del Belice variety, one cultivated in the olive areas of the Sicily region, Italy. Destoned oils obtained by processing olives with a destoning-based procedure were compared with conventional oils. This innovat...

journal_title：Natural product research

authors： Ranalli F,Ranalli A,Contento S,Casanovas M,Antonucci M,Simone GD

更新日期：2013-01-01 00:00:00

abstract：:Illicium lanceolatum is a popular aromatic and medicinal plant in China. Essential oil from the roots of I. lanceolatum, obtained by hydrodistillation, was analysed by GC-MS. The essential oil was dominated by phenylpropenes. The major components were myristicin (17.63%), α-asarone (17.23%), methyl isoeugenol (11.19%)...

journal_title：Natural product research

authors： Liang J,Huang B,Wang G

更新日期：2012-01-01 00:00:00

abstract：:New analogues of a long-chain secondary alcohol (1) and laserine (2) were isolated from the flowers of Tamarix hampeana L. The isolated compounds were identified using 1D and 2D NMR, LCMS/APCI, and chemical methods. Laserine was isolated for the first time from T. hampeana L. ...

journal_title：Natural product research

authors： Aykac A,Akgül Y

更新日期：2010-01-01 00:00:00

abstract：:Development of natural nano-based plant-protection formulations represents an emerging phenomenon that has been widely improved for crops protection and for enhancing the efficiency and safety of pesticides. In the present study we isolated the essential oil from the fruits of Citrus trifoliata L. and investigated it ...

journal_title：Natural product research

authors： Abdel-Kawy MA,Michel CG,Kirollos FN,Hussien RAA,Al-Mahallawi AM,Sedeek MS

更新日期：2019-10-09 00:00:00

abstract：:A new sesquiterpeniod, 6alpha, 7alpha, 10alpha-trihydroxyisoducane (1), together with two known sesquiterpenoids, oplodiol (2) and oplopanone (3), were isolated from the chloroform extract of the rhizomes of Homalomena occulta. Their structures were elucidated by 1D and 2D NMR spectral interpretation. ...

journal_title：Natural product research

authors： Hu YM,Yang ZL,Wang H,Ye WC

更新日期：2009-01-01 00:00:00

abstract：:A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/...

journal_title：Natural product research

authors： Michael BR,Gedara SR,Amer MM,Stevenson L,Ahmed AF

更新日期：2013-01-01 00:00:00

abstract：:This study discusses the similarities and differences between the antioxidant activities of some essential oils: thyme (Thymus vulgaris), basil (Ocimum basilicum), peppermint (Mentha piperita), clove (Caryophyllus aromaticus), summer savory (Satureja hortensis), sage (Salvia hispanica) and lemon (Citrus limon (L.) Bur...

journal_title：Natural product research

authors： Dawidowicz AL,Olszowy M

更新日期：2014-01-01 00:00:00

abstract：:An unexpected synthesis of symmetrical hydroxybiphenylmethanes involving the reaction of 2-hydroxyphenyl benzyl ketones with ethoxymethyl chloride has been observed. Some new interesting observations of Labat test on colorimetric detection of bichalconyloxy, bichalconyl and biflavonylmethanes having oxygenated ortho p...

journal_title：Natural product research

authors： Kukreja G,Campiani G,Khurana JM,Joshi BP,Grover SK

更新日期：2006-10-01 00:00:00

abstract：:Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...

journal_title：Natural product research

authors： Oliveira ICF,Mora AD,Neto JB,de Oliveira ÁL,Harder C,Hanai-Yoshida VM,Cogo JC,Floriano RS,Bonventi Junior W,Oliveira SJ,Oshima-Franco Y

更新日期：2019-08-01 00:00:00

abstract：:The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...

journal_title：Natural product research

authors： Chen MH,Lian YY,Fang DS,Chen L,Jia J,Zhang WL,Lin R,Xie Y,Bi HK,Jiang H

更新日期：2019-11-15 00:00:00

abstract：:The importance of the present study is to find out the phytochemical profile of essential oil (EO) of Artemisia tournefortiana Reichb. and its biological evaluation. Nineteen volatile constituents were identified from EO representing 93.47% of total oil composition. Oxygenated monoterpenes (54.46%) were found to be do...

journal_title：Natural product research

authors： Qadir M,Maurya AK,Agnihotri VK,Shah WA

更新日期：2021-01-01 00:00:00

abstract：:Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...

journal_title：Natural product research

authors： Dalmagro AP,Camargo A,Zimath PL,Bonomini TJ,Zeni ALB,Malheiros A,de Souza MM

更新日期：2020-03-11 00:00:00

abstract：:Besides the chemotaxonomic value, nowadays determination of biodiversity and chemical variability has a commercial impact. The exact identity of raw material and constituents of botanical products, such as food supplements or herbal remedies, is a very important argument, being the real prerequisite for quality contro...

journal_title：Natural product research

authors： Toniolo C,Nicoletti M,Maggi F,Venditti A

更新日期：2014-01-01 00:00:00

abstract：:The microbial transformation studies of 7-O-prenylquercetin (1), 4'-O-prenylquercetin (2) and quercetin (3) were investigated with 20 different microbial strains to discover new metabolites. It was revealed that the fungus Mucor hiemalis was the most appropriate micro-organism which was capable of transforming these f...

journal_title：Natural product research

authors： Xiao Y,Lee IS

更新日期：2018-04-01 00:00:00

abstract：:Stichopus hermanni and Stichopus vastus are sea cucumber species from the Stichopodidae family within the coastal waters of Malaysia. The integument of these invertebrates is hypothesised to contain abundant glycosaminoglycans (GAGs). GAGs are divided into non-sulphated and sulphated GAGs. Sulphated GAGs have various ...

journal_title：Natural product research

authors： Masre SF,Yip GW,Sirajudeen KN,Ghazali FC

更新日期：2012-01-01 00:00:00

abstract：:A series of isoquinoline alkaloids including tetrahydroprotoberberines, N-methyl tetrahydroprotoberberines and protoberberines were facile synthesised with protopines as the starting material. All compounds were evaluated for their antibacterial activities against four pathogenic bacteria Escherichia coli, Staphylocco...

journal_title：Natural product research

authors： Cheng P,Wang B,Liu X,Liu W,Kang W,Zhou J,Zeng J

更新日期：2014-01-01 00:00:00

abstract：:The Aedes aegypti mosquito is one of the major vectors of arboviruses. These diseases have re-emerged and the insecticides used nowadays are toxic to mammals and environment and have only been effective in the short-term. In this context, natural products are an alternative. The genus Piper has many active compounds a...

journal_title：Natural product research

authors： Macedo AL,Duprat RC,Moreira DL,Kaplan MAC,Vasconcelos TRA,Pinto LC,Montenegro RC,Ratcliffe NA,Mello CB,Valverde AL

更新日期：2018-11-01 00:00:00

abstract：:A new prenylated indole alkaloid, named paraherquamide J (1), together with four known compounds (2-5), were isolated from the mangrove rhizosphere soil-derived fungus Penicillium janthinellum HK1-6. The planar structure and relative configuration of 1 were determined by detailed analysis of the spectroscopic data esp...

journal_title：Natural product research

authors： Zheng YY,Shen NX,Liang ZY,Shen L,Chen M,Wang CY

更新日期：2020-02-01 00:00:00