New labdane diterpenes from Solidago canadensis.

Abstract:

:The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6a) and 13-epi-15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6b). The known labdane diterpenes deoxysolidagenone (1), solidagenone (2) and 15,16-epoxy-labdane-7,13-diene-6,15-dione (4) were also isolated. Chemical structures were determined using 1D and 2D NMR techniques and MS analysis.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Wangensteen H,Phan TT,Rise F,Halvorsen TG,Malterud KE

doi

10.1080/14786419.2011.565005

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

1348-54

issue

14

eissn

1478-6419

issn

1478-6427

journal_volume

26

pub_type

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