Phenanthrene and dihydrophenanthrene derivatives from Dioscorea communis with anticholinesterase, and antioxidant activities.

abstract：:A new sesquiterpenoid glycoside, consisting of one vetispirane-type, dmetelisproside A (1), together with two known megastigmane sesquiterpenoids, citroside A (2) and staphylionoside D (3) were isolated from the leaves of Datura metel L. The structures were determined by analysis of their MS and NMR data as well as by...

journal_title：Natural product research

authors： Guo R,Liu Y,Pan J,Guan W,Yang BY,Kuang HX

更新日期：2019-03-28 00:00:00

abstract：:Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-g...

journal_title：Natural product research

authors： Phan HV,Devi AP,Le HD,Nguyen TT,Nguyen HH,Le TT,Nguyen TH,Sichaem J,Duong TH

更新日期：2020-01-27 00:00:00

abstract：:Two new flavans, named (2S)-2',4'-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2'-hydroxy-4',7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2...

journal_title：Natural product research

authors： Tang BQ,Huang SS,Liang YE,Sun JB,Ma Y,Zeng B,Lee SM,Lu JL

更新日期：2017-07-01 00:00:00

abstract：:Coumarin (2H-1-benzopyran-2-one) is a phenolic compound derived from the shikimate pathway and synthesized by various medicinal and aromatic plants as parent molecule of a large group of secondary metabolites, namely coumarins. Its main utilization is as fixative in perfumes and flavour enhancer. Given its role as phy...

journal_title：Natural product research

authors： Pavela R,Maggi F,Benelli G

更新日期：2019-09-11 00:00:00

abstract：:Mangrove plants are endowed with various biologically active compounds which have potent antibacterial and antioxidant properties. In present study, a bioactivity-guided fractionation for antibacterial and antioxidant active metabolites from the twigs of Avicennia officinalis collected from Kuala Selangor Nature Park,...

journal_title：Natural product research

authors： Assaw S,Mohd Amir MIH,Khaw TT,Bakar K,Mohd Radzi SA,Mazlan NW

更新日期：2020-08-01 00:00:00

abstract：:The ethanol extract of Stellera chamaejasme roots exhibited significant bioactivity against Peries rapae. In the course of a search for the active compounds, S-(+)-1,5-diphenyl-3-hydroxy-1-pentanone (1) was isolated and this compound has never been found before in S. chamaejasme as far as we known. The structure was e...

journal_title：Natural product research

authors： Liu Q,Jia H,Xiao B,Chen L,Zhou B,Hou TP

更新日期：2008-03-10 00:00:00

abstract：:In an attempt to establish the components responsible for the use of Enantia chlorantha against cutaneous leishmaniasis in local traditional medicine, a well-known palmatine has been isolated in substantial amounts from a methanolic bark extract of this plant species. Palmatine therein obtained exhibited a significant...

journal_title：Natural product research

authors： Nkwengoua ET,Ngantchou I,Nyasse B,Denier C,Blonski C,Schneider B

更新日期：2009-01-01 00:00:00

abstract：:In the present investigation, the anti-inflammatory activity of a polyphenolic enriched extract of Schima wallichii bark was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs) and in vivo by carrageenan-induced paw oedema assay (acute study) and cotton pallet granuloma assay (chronic study). The...

journal_title：Natural product research

authors： Dewanjee S,Mandal V,Sahu R,Dua TK,Manna A,Mandal SC

更新日期：2011-04-01 00:00:00

abstract：:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6'-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures w...

journal_title：Natural product research

authors： Pang X,Wang LM,Zhang YC,Kang LP,Yu HS,Fan GW,Han LF

更新日期：2019-12-01 00:00:00

abstract：:Eight known abietane diterpenes (1-8) were isolated for the first time from Abies numidica cones (Pinaceae). The structures of all compounds were established by means of 1D and 2D NMR, and UV spectral analyses. The hydromethanolic extract of A. numidica cones was tested for its antimicrobial activity against 17 gram-p...

journal_title：Natural product research

authors： Belhadj Mostefa M,Abedini A,Voutquenne-Nazabadioko L,Gangloff SC,Kabouche A,Kabouche Z

更新日期：2017-03-01 00:00:00

abstract：:A new cycloartane triterpene bisdesmoside, soulieoside T (1), and one known compound, oleanolic acid (2), were isolated from the ethanolic extract of the rhizomes of Actaea vaginata. Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compound 1 was evaluat...

journal_title：Natural product research

authors： Zhang M,Yang Q,Zhang X,Wu H

更新日期：2019-12-10 00:00:00

abstract：:A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...

journal_title：Natural product research

authors： Li HM,Liu D,Dai WF,Chen XQ,Li RT

更新日期：2019-11-01 00:00:00

abstract：:A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...

journal_title：Natural product research

authors： Yu J,Yin TP,Wang JP,Mei RF,Cai L,Ding ZT

更新日期：2017-01-01 00:00:00

abstract：:Fructose feeding induces a rise in blood pressure in normal rats that is associated with insulin resistance, hyperinsulinemia, hyperglycaemia, hypercholesterolaemia and hypertriglyceridaemia. We have examined the effect of chronic administration of A-HRS (100 and 300 mg kg⁻¹; p.o.) isolated from Hibiscus rosa sinensis...

journal_title：Natural product research

authors： Mohan M,Khade B,Shinde A

更新日期：2012-01-01 00:00:00

abstract：:Chronic neuroinflammation is a key component of many neurodegenerative disorders. Chronic activation of this process produces pro-inflammatory cytokines, prostaglandins and reactive oxygen species that induce brain injury and neuronal dysfunction. Agave species contain saponins, compounds with anti-inflammatory activi...

journal_title：Natural product research

authors： Herrera-Ruiz M,Jiménez-Ferrer E,Tortoriello J,Zamilpa A,Alegría-Herrera E,Jiménez-Aparicio AR,Arenas-Ocampo ML,Martínez-Duncker I,Monterrosas-Brisson N

更新日期：2019-05-14 00:00:00

abstract：:In the present study, profiles of fatty acid, sn-2 fatty acid, triglyceride, phytochemical (including tocopherol/tocotrienol, phytosterol, flavonoid, carotenoid and polyphenol) and antioxidant capacity of extracts from the whole berry, pulp and seed of Hippophae¨ rhamnoides ssp. yunnanensis were investigated and compa...

journal_title：Natural product research

authors： Shi L,Zheng L,Zhao C,Jin Q,Wang X

更新日期：2019-12-01 00:00:00

abstract：:Two new glycerol esters, (S)-2-hydroxy-3-(octanoyloxy)propyl tetracosanoate (1) and (S)-3-(((S)-11-acetoxy octadecanoyl)oxy)propane-1,2-diyl diacetate (2), and eight known compounds, docosanedioic acid (3), 2,5-dimethylnonadecane (4), lupeol (5), stigmasterol (6), β-sitosterol (7), heptadecanoic acid (8), hexanedioic ...

journal_title：Natural product research

authors： Forestrania RC,Anaya-Eugenio GD,Acuña UM,Ren Y,Elya B,de Blanco EC

更新日期：2020-06-12 00:00:00

abstract：:This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...

journal_title：Natural product research

authors： Dias ALB,Batista HRF,Sousa WC,Bailão EFLC,Rocha JD,Sperandio EM,Fernandes CC,Souchie EL,Miranda MLD

更新日期：2020-11-09 00:00:00

abstract：:Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...

journal_title：Natural product research

authors： Pandya U,Dhuldhaj U,Sahay NS

更新日期：2019-09-01 00:00:00

abstract：:Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...

journal_title：Natural product research

authors： Spinelli R,Aimaretti FM,López JA,Siano AS

更新日期：2019-03-31 00:00:00

abstract：:Timosaponin AIII (TAIII) exhibits extensive pharmacological activities and has been reported as a potent antitumour agent for various human cancers. In the present study, a potential industrial process for producing TAIII that involves biotransformation directly in the crude extract liquid of rhizoma anemarrhenae (RA)...

journal_title：Natural product research

authors： Lu L,Liu Y,Ding Y,Hou J,Zhang Y,Xue H,Zhang T

更新日期：2016-10-01 00:00:00

abstract：:Chemical investigation of Dendrobium plicatile Lindl resulted in the isolation and identification of one new bibenzyl, 2-chloro-3, 4'-dihydroxy-3',5-dimethoxybibenzyl (1), as well as 15 known stilbenoids. The structures of this new compound was elucidated by extensive spectroscopic analysis, including HRESIMS, 1H and ...

journal_title：Natural product research

authors： Chen DN,Wang YY,Liu WJ,Chen YJ,Wu YP,Wang JX,He F,Jiang L

更新日期：2020-02-01 00:00:00

abstract：:The crystal structure and unambiguous absolute configuration of meleagrin (1) isolated from fungus Emericella dentata Nq45 is reported herein to first time on the bases of single crystal X-ray diffraction. Together with 1, haenamindole (2), isorugulosuvine (3), secalonic acid D (4), ergosterol (5) and cerebroside A (6...

journal_title：Natural product research

authors： Hamed A,Abdel-Razek AS,Araby M,Abu-Elghait M,El-Hosari DG,Frese M,Soliman HSM,Stammler HG,Sewald N,Shaaban M

更新日期：2020-03-19 00:00:00

abstract：:The aims of the present study were to determine the antibacterial activity of bark extract of Cryptomeria japonica D. Don and to isolate potential antibacterial constituents. The results showed that the ethanolic extract of C. japonica bark possessed a good antibacterial activity. Nine compounds including seven diterp...

journal_title：Natural product research

authors： Li WH,Chang ST,Chang SC,Chang HT

更新日期：2008-01-01 00:00:00

abstract：:The Nigerian and South African varieties of Siphonochilus aethiopicus were examined for their phytochemical constituents. The ethyl acetate extract of the rhizomes of the South African variety yielded a novel diarylheptanoid, 2,3-diacetoxy-7-(3'',4''-dihydroxy-5''-methoxyphenyl)-1-(4'-hydroxy-3'-methoxyphenyl)-5-hepte...

journal_title：Natural product research

authors： Igoli NP,Al-Tannak NF,Ezenyi IC,Gray AI,Igoli JO

更新日期：2020-07-27 00:00:00

abstract：:A new dehydrodigallic acid derivative (1), along with 19 known compounds, including 6 phenolic derivatives, 2 steroids and 11 triterpenoids were isolated from the ethanol extract of the root of Geum urbanum. Herein, there is the first report of steroid and triterpene in Geum urbanum. The purified metabolites were char...

journal_title：Natural product research

authors： Ton That Q,Nguyen Thien TV,Dang HP,Le Hoan N,Vo LKT,Nguyen MHD,Ngu NT,Nguyen TS,Hansen PE

更新日期：2018-11-01 00:00:00

abstract：:The stems of Cinnamomum reticulatum Hay (Lauraceae) were extracted with hexane and chloroform successively. A series of new esters, including a mixture of 4-hydroxy-3-methoxyphenethyl derivatives, along with two butanolides, isoobtusilactone A and obtusilactone A, two amides, N-trans-feruloylmethoxytyramine and N-cis-...

journal_title：Natural product research

authors： Lin IJ,Lo WL,Chia YC,Huang LY,Cham TM,Tseng WS,Yeh YT,Yeh HC,Wang YD,Chen CY

更新日期：2010-05-01 00:00:00

abstract：:Benign prostatic hypertrophy (BPH) is a common condition in elderly men that impairs quality of life and leads to a number of medical complications. The use of phytotherapeutic compounds in patients with relatively moderate BPH symptoms has been growing steadily. In the present study, acute toxicity of lyophilised aqu...

journal_title：Natural product research

authors： Vitali F,Pennisi G,Attaguile G,Savoca F,Tita B

更新日期：2011-02-01 00:00:00

abstract：:Two novel benzoquinones, uvarmicranones A (1) and B (2), along with 15 known compounds (3 - 17) were isolated from the stems of Uvaria micrantha (Annonaceae). Their structures were elucidated by analyses of NMR and high-resolution mass data. A plausible biosynthetic pathway of uvarmicranone A (1) via Diels-Alder cyclo...

journal_title：Natural product research

authors： Boonsombat J,Thongnest S,Kheawchaum S,Mahidol C,Ruchirawat S,Prawat H

更新日期：2020-09-22 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00