Abstract:
:Cochliomycin G (1), a new 14-membered resorcylic acid lactone, together with six known analogues (2-7), was isolated from the culture broth of a marine-derived fungus Cochliobolus lunatus. The planar structure of 1 was established by extensive NMR spectroscopy, and the absolute configuration was elucidated by the combination of empirical rules, CD data, and 13C chemical shift calculations. Compound 1 exhibited potent antifouling activity against Chlorella vulgaris, Chaetoceros socialis, and Navicula exigua, with EC50 values of 1.09, 0.92, and 0.61 μg/mL, respectively.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Xu WF,Xue XJ,Qi YX,Wu NN,Wang CY,Shao CLdoi
10.1080/14786419.2019.1633646subject
Has Abstractpub_date
2021-02-01 00:00:00pages
490-493issue
3eissn
1478-6419issn
1478-6427journal_volume
35pub_type
杂志文章abstract::A phytochemical investigation of Ajuga forrestii Diels led to the isolation of 14 compounds, including eight neo-clerodane diterpenes (1-8), two phytoecdysteroids (9, 11), one stigmastane sterol (10) and three iridoid glycosides (12-14). The structures of these compounds were identified by spectroscopic methods and a ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1371161
更新日期:2018-04-01 00:00:00
abstract::A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Amon...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.902946
更新日期:2014-01-01 00:00:00
abstract::Chemical investigation of Dendrobium plicatile Lindl resulted in the isolation and identification of one new bibenzyl, 2-chloro-3, 4'-dihydroxy-3',5-dimethoxybibenzyl (1), as well as 15 known stilbenoids. The structures of this new compound was elucidated by extensive spectroscopic analysis, including HRESIMS, 1H and ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1530996
更新日期:2020-02-01 00:00:00
abstract::Two new flavonoids, 8-hydroxyisoscoparin (1) and luteolin 7-O-glucoside 4''-sulfate (2), along with eight known flavonoids, including luteolin 7-O-glucoside 2''-sulfate, were isolated and identified from Washingtonia filifera. All compounds were characterized by (1)H-NMR, (13)C-NMR, CI-MS, FABMS and UV. The antioxidan...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1478641500059276
更新日期:2006-01-01 00:00:00
abstract::Three new flavonol glycosides (1-3), hippophins K-M, were isolated from the seed residue of Hippophae rhamnoides subsp. sinensis. The chemical structures of these three new compounds were identified by 1D, 2D NMR, mass spectroscopy and high resolution electrospray ionization mass spectrometry spectroscopic data and by...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.830216
更新日期:2014-01-01 00:00:00
abstract::Bioactivity guided fractionation of Echiochilon fruticosum Desf. (Boraginaceae) butanolic extract biautography assay against fungi led to the isolation of a new bioactive alkaloid, named saoussanabiloïde (1). Its structure was established on the basis of spectroscopic measurements, IR, MS and 2D NMR using COSY, HMQC a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267619
更新日期:2009-01-01 00:00:00
abstract::Two new flavanone glycosides have been isolated from the water soluble part of Veratrum nigrum L., belonging to the family Lilica. The structures of 3',4'-dimethoxyl-quercitrin and 4'-methoxyl-glucotricin have been established with the aid of extensive NMR spectroscopic studies. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410801887664
更新日期:2009-01-01 00:00:00
abstract::In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored. Compound 1 showed a marked concentration-dependent inhibition against 12-O-tetradecanoylphorbol-13-acetate (20 ng/32 pmol)-induced...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046381
更新日期:2016-01-01 00:00:00
abstract::Two new C-15 enolic acyl phragmalin-type limonoid orthoesters, chukvelutilide G (1) and chukrasine F (2), were isolated from the stem barks of Chukrasia tabularis var. velutina. Their structures were elucidated by their extensive high resolution-electrospray ionization mass spectrometry (HR-ESI-MS), one- and two-dimen...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.682995
更新日期:2013-04-01 00:00:00
abstract::This study investigated the pharmacokinetics of hesperidin (HP), ferulic acid (FA) and p-coumaric acid (CA) in rat plasma after oral administration of Portulaca oleracea L. extract (POE). The plasma concentrations were determined by HPLC with vitexin-2″-O-rhamnoside (VR) as internal standard. The calibration curves we...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.648193
更新日期:2012-01-01 00:00:00
abstract::Four new and seven known diterpenes have been isolated from the dichloromethane extract of the aerial parts of Calceolaria polifolia. The structures of the new compounds were established by spectroscopic evidence. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500202033
更新日期:2007-02-01 00:00:00
abstract::Pseudomonas syringae pv. actinidiae (PSA) is the causal agent of bacterial canker of kiwifruit. It is very difficult to treat pandemic disease. The prolonged treatment with antibiotics, has resulted in failure and resistance and alternatives to conventional antimicrobial therapy are needed. The aim of our study was to...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1022543
更新日期:2016-01-01 00:00:00
abstract::A new isoflavone, 4'-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2'-dimethoxy-3',4...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1462179
更新日期:2019-09-01 00:00:00
abstract::Pigeon Pea is a well-received traditional nutritious and medicinal plant in India since ancient times. The plant is identified for its impressive pharmacological activities like antimicrobial, anti-inflammatory, antitubercular, antioxidant, neuroprotective, antihypertensive, antihyperglycemic and anticancer properties...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1849197
更新日期:2020-11-23 00:00:00
abstract::Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1737052
更新日期:2020-03-11 00:00:00
abstract::Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp. In addition, another new benzoic acid 10 with an unusual 1,2-dicarbonyl side chain was indirectly identified from its...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001620637
更新日期:2004-06-01 00:00:00
abstract::N-methylasimilobine (1), a new-found strong acetylcholinesterase (AChE) inhibitor, along with two weakly active aporphine alkaloids, nuciferine (2) and nornuciferine (3) were separated from Nelumbo nucifera. N-methylasimilobine (1) inhibited 50% of AChE activity at the concentrations of 1.5 ± 0.2 µg mL(-1) when the st...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.487188
更新日期:2012-01-01 00:00:00
abstract::The present work describes the metabolites produced by a strain identified as Streptomyces youssoufiensis, whose secondary metabolites profile has not been studied so far. The crude ethyl acetate extract was analyzed by high performance liquid chromatography-electrospray ionization mass spectrometry, leading to the de...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1446014
更新日期:2019-01-01 00:00:00
abstract::Tannic acid, a rich of natural and process-derived phenolic compound, has been shown to be an effective antagonist against viruses and bacteria. In this study, we determined the antimicrobial activity and mechanisms of tannic acid against Staphylococcus aureus with emphasis on inhibiting effect on biofilm formation. B...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1366485
更新日期:2018-09-01 00:00:00
abstract::The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.983918
更新日期:2015-01-01 00:00:00
abstract::Twenty-one phenolic compounds (1-21) including dihydrocinnamic acid, isoflavonoids, flavonoids, coumestans, pterocarpans, chalcones, isoflavan and isoflaven, were isolated from the roots of Glycyrrhiza pallidiflora Maxim. Phloretinic acid (1), chrysin (6), 9-methoxycoumestan (8), isoglycyrol (9), 6″-O-acetylanonin (19...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1188094
更新日期:2017-02-01 00:00:00
abstract::A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), β-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the et...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1359172
更新日期:2018-04-01 00:00:00
abstract::A new triterpene saponin (1) was isolated from a methanol extract of Swartzia apetala Raddi var. glabra, together with the flavonoids mauritianin (2), kaempferol (3) and the triterpene saponin β-D-glucopyranosyl 3β-hydroxy-olean-12-en-28-oate (4). These compounds were characterised on the basis of their spectral data,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.782493
更新日期:2013-10-01 00:00:00
abstract::A new diterpenoid, 15-epi-(4E)-jatrogrossidentadione acetate, along with several known constituents has been isolated from the stem of Jatropha multifida. The structure of the new compound was settled by a detailed analysis of its 1D- and 2D-NMR spectra. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003792207
更新日期:2010-10-01 00:00:00
abstract::A simple and efficient method was developed for simultaneous analysis of five illegal residual β2-agonists in cattle hair. β2-Agonists were quantified by ultra high performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry operating in positive multiple-reaction monitoring mode. T...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1190718
更新日期:2017-02-01 00:00:00
abstract::The aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizomes of C. zedoaria were immersed in four kinetin concentrations (0, 50, 100, 150 mg ml-1, n = 12 by each concentration) for 30 min....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1729152
更新日期:2020-02-21 00:00:00
abstract::This study investigated the in vitro anticancer potential of phytochemical constituents isolated from the methanolic extract of Eriocephalus africanus. One flavanone (hesperidin) and two flavones (luteolin and apigenin) were isolated for the first time from the plant using column chromatography. Standard MTT assay was...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1744138
更新日期:2020-03-25 00:00:00
abstract::The methanol extract of the root cortex of Paeonia suffruticosa afforded two new monoterpene glycosides, paeoniside A (1) and paeoniside B (2), and three known monoterpene glycosides, paeoniflorin (3), benzoylpaeoniflorin (4) and 4-O-methyl-paeoniflorin (5). Their structures were elucidated on the basis of spectroscop...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.858340
更新日期:2014-01-01 00:00:00
abstract::The chemical investigation of whole plants Piper terminaliflorum Tseng led to the isolation of one new furofuran lignan, 7-methoxyasarinin (1), along with three known amide alkaloids (2-4) as N-3,5-dimethoxy-4-hydroxycinnamoylpyrrole (2), dihydropipercide (3) and 1-[(2E,4E,9E)-10-(3,4-Methylenedioxyphenyl)-2,4,9-undec...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1350671
更新日期:2018-02-01 00:00:00
abstract::The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1644505
更新日期:2019-07-25 00:00:00