Octyl substituted butenolides from marine-derived Streptomyces koyangensis.

abstract：:From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2-4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor ...

journal_title：Natural product research

authors： Lin YK,Xie CL,Xing CP,Wang BQ,Tian XX,Xia JM,Jia LY,Pan YN,Yang XW

更新日期：2019-06-24 00:00:00

abstract：:The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7). A GC analysis was carri...

journal_title：Natural product research

authors： Benedetto C,D'Auria M,Mecca M,Prasad P,Singh P,Singh S,Sinisgalli C,Milella L

更新日期：2019-08-01 00:00:00

abstract：:Three new aconitine-type C19-diterpenoid alkaloids, taipeinines A-C (1-3), were isolated from the roots of Aconitum taipaicum. The chemical structures of these three compounds were established as (1α,6α,8α,14α,16α)-20-ethyl-8,14-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane (1), (1α,6α,8α,14α,16β)-20-ethyl-8...

journal_title：Natural product research

authors： Guo ZJ,Xu Y,Zhang H,Li MY,Xi K

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to investigate the influence of both facility location and typology of fish farm on some ecotoxicological, qualitative and reproductive variables in European sea bass Dicentrarchus labrax L. Several variables were investigated: gonado-somatic index (GSI), liver-somatic index (LSI); 7-ethoxyre...

journal_title：Natural product research

authors： Cangialosi MV,Corsi I,Bonacci S,Sensini C,Cicero N,Focardi S,Mazzola A

更新日期：2013-04-01 00:00:00

abstract：:Phytochemical investigation of the stem and root barks of Friesodielsia obovata Benth (Annonaceae) afforded new 3',5'-diformyl-2',4',6'-trihydroxychalcone and N-formyl-7-hydroxyglaucine together with five known compounds, 3',5'-dimethyl-2',4',6'-trihydroxychalcone, (-)-crotepoxide, demethoxymatteucinol, lawinal, and b...

journal_title：Natural product research

authors： Joseph CC,Magadula JJ,Nkunya MH

更新日期：2007-09-01 00:00:00

abstract：:Juniperus chinensis cv. Kaizuca has extensive pharmacological activities. The cone oils exhibited protein tyrosine phosphatase 1B inhibitory activity in vitro. The IC50 value was 4.49 ± 0.04 μg/mL. A total of 17 compounds were characterised from the cone oils by GC-MS. In order to explain the activity against protein ...

journal_title：Natural product research

authors： Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

更新日期：2018-11-01 00:00:00

abstract：:The essential oils obtained by hydrodistillation from the leaves of Tabernaemontana catharinensis had their composition analysed by GC-MS. A total of 18 substances were identified, consisting of a complex mixture of sesquiterpenes (83.52%), monoterpenes (5.46%) and triterpenes (4.56%). The main components in the oil w...

journal_title：Natural product research

authors： Boligon AA,Schwanz TG,Piana M,Bandeira RV,Frohlich JK,de Brum TF,Zadra M,Athayde ML

更新日期：2013-01-01 00:00:00

abstract：:The optimisation of nutritional requirements for dopamine (DA) synthesis by calcium alginate-entrapped mutant variant of Aspergillus oryzae EMS-6 using submerged fermentation technique was investigated. A total of 13 strains were isolated from soil. Isolate I-2 was selected as a better producer of DA and improved by e...

journal_title：Natural product research

authors： Ali S,Nawaz W

更新日期：2017-02-01 00:00:00

abstract：:To search for possible cancer chemopreventive agents from natural sources, we performed primary screening of metabolites of Alternaria porri by examining their possible inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. The et...

journal_title：Natural product research

authors： Horiuchi M,Tokuda H,Ohnishi K,Yamashita M,Nishino H,Maoka T

更新日期：2006-02-01 00:00:00

abstract：:Cathepsin B (catB) is a cysteine protease involved in tumour progression and represents a potential therapeutic target in cancer. Among the 15 evaluated extracts from cerrado biome, Myrcia lingua Berg. (Myrtaceae) extract demonstrated to be a source of compounds with potential to inhibit catB. Using bioactivity-guided...

journal_title：Natural product research

authors： Ramalho SD,de Sousa LR,Burger MC,Lima MI,da Silva MF,Fernandes JB,Vieira PC

更新日期：2015-01-01 00:00:00

abstract：:Alkylglycerols (AKGs) are bioactive natural compounds that vary by alkyl chain length and degree of unsaturation, and their absolute configuration is 2S. Three AKGs (5l-5n) were synthesised in enantiomerically pure form, and were characterised for the first time together with 12 other known and naturally occurring AKG...

journal_title：Natural product research

authors： Fernández Montoya DJ,Contreras Jordan LA,Moreno-Murillo B,Silva-Gómez E,Mayorga-Wandurraga H

更新日期：2019-11-04 00:00:00

abstract：:Three new diterpenoids, liquidambolide A (1) and liquiditerpenoic acids A (2) and B (3), together with 10 known diterpenes were isolated from the resin of Liquidambar formosana Hance, whose structures were elucidated by detailed analysis on the NMR and HR-ESI-MS spectra. ...

journal_title：Natural product research

authors： Shang HJ,Li DY,Wang WJ,Li ZL,Hua HM

更新日期：2014-01-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:The chemical composition of the essential oil of Kurzamra pulchella (Lamiaceae) was determined. Twelve compounds were identified, with isomenthone (60.6%) and pulegone (37.1%) predominating. Chemotaxonomical considerations were discussed. ...

journal_title：Natural product research

authors： Echeverría J,Niemeyer HM

更新日期：2017-01-01 00:00:00

abstract：:A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives we...

journal_title：Natural product research

authors： Fei P,Chuan-Xi W,Yang X,Hong-Lei J,Lu-Jie C,Uribe P,Bull AT,Goodfellow M,Hong J,Yun-Yang L

更新日期：2013-08-01 00:00:00

abstract：:Marsdenia tinctoria is an indigo producing plant commonly found in Borneo, Malaysia. In this present study, one new flavone kapitone (1) and three known compounds, that is 3,2'-dihydroxyflavone (2), 1-methylcyclobutene (3) and dimethyl isatoate (4) were isolated from the Malaysia Borneo M. tinctoria R. Br. (Apocynacea...

journal_title：Natural product research

authors： Mohd Nasuha NA,Choo YM

更新日期：2016-07-01 00:00:00

abstract：:Mahuang Fuzi Xixin (MFX), a classic recipe in traditional Chinese medicine, belongs to an exterior-relieving formula. For quality control of the MFX products, qualitative analysis using ultra-high performance liquid chromatography with diode-array detector-tandem mass spectrometry (UPLC-PDA-MS/MS) was undertaken. Six ...

journal_title：Natural product research

authors： Zhang L,Wang C,Miao D,Yuan D,Bi K,Yang J,Zhan L

更新日期：2015-01-01 00:00:00

abstract：:Two new norsesquiterpenes were isolated from the extracts of the roots and rhizomes of Ligularia lapathifolia (Franch.) Hand.-Mazz. Their structures were identified as 2-acetyl-3a-methyl-5-(2-methyl-but-2-enoyloxy)-3a,4,5,6,7,7a-hexahydro-H-indene-4-carboxylic acid (1) and 2-acetyl-8a-methyl-2-(2-methyl-but-2-enoyloxy...

journal_title：Natural product research

authors： Li YS,Wang ZT,Zhang M,Chen JJ,Luo SD

更新日期：2004-04-01 00:00:00

abstract：:Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...

journal_title：Natural product research

authors： Pandya U,Dhuldhaj U,Sahay NS

更新日期：2019-09-01 00:00:00

abstract：:Two new flavonoids, 3, 3', 4' -Trihydroxy- 6, 7, 8 -trimethoxy flavone (1) and 3-Hydroxy-6, 7, 8, 3', 4'-pentamethoxy flavone (2) have been isolated from the methanol extract of Blumea eriantha DC. The structures of these compounds were determined on the basis of spectroscopic techniques such as IR, MS, 1 D, and 2 D N...

journal_title：Natural product research

authors： Tambewagh UU,Javir GR,Joshi KS,Rojatkar SR

更新日期：2019-10-03 00:00:00

abstract：:The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against...

journal_title：Natural product research

authors： Ushimaru PI,Barbosa LN,Fernandes AA,Di Stasi LC,Fernandes A Jr

更新日期：2012-01-01 00:00:00

abstract：:Two new ent-atisanes ent-1β,3β,16β,17-tetrahydroxyatisane (1), ent-1β,3α,16β,17-tetrahydroxyatisane (2) together with 11 known diterpenes were isolated from the anti-tumour activity fraction of Euphorbia fischeriana Steud. The compounds were identified by detailed spectroscopic analysis, including extensive 2D-NMR exp...

journal_title：Natural product research

authors： Wang M,Wang Q,Wei Q,Li J,Guo C,Yang B,Kuang H

更新日期：2016-01-01 00:00:00

abstract：:Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketid...

journal_title：Natural product research

authors： Ebada SS,Fischer T,Hamacher A,Du FY,Roth YO,Kassack MU,Wang BG,Roth EH

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study is to estimate the nutritive values, metabolites of Hass and Reed Avocado cultivars and evaluate their antimicrobial and anticancer activities. Hass was rich in water soluble vitamins, iron and calcium while, Reed contains more fat soluble vitamins. Benzaldehyde and butyl phenol derivatives were ...

journal_title：Natural product research

authors： Younis IY,Hifnawy MS,El-Hawary SS,El Bishbishy MH,Elateek SY

更新日期：2020-09-11 00:00:00

abstract：:From a biologically active fraction of extract from the fungus Fomitopsis pinicola, a new lanostane triterpene was isolated, 3alpha-acetyloxylanosta-8,24-diene-21-ol (1), along with two known triterpenic acids, (2) and (3). The structures of the compounds were elucidated based on their spectral properties. [structure:...

journal_title：Natural product research

authors： Petrova A,Popov S,Gjosheva M,Bankova V

更新日期：2007-05-01 00:00:00

abstract：:A series of unexpected triterpenic C17-[5-methyl-1,3]-oxazoles along with targeted N-propargylamides was synthesized by an interaction of acid chlorides with propargylamine hydrochloride. We proposed that the formation of methyl oxazole passes through an alternative pathway by the participation of the terminal alkyne ...

journal_title：Natural product research

authors： Khusnutdinova EF,Petrova AV,Lobov AN,Kukovinets OS,Baev DS,Kazakova OB

更新日期：2020-03-28 00:00:00

abstract：:Five new α-pyrones, xylariaopyrones E-I (1-5), along with three known analogues (6-8) were isolated from the cultivation broth of the endophytic fungus Xylariales sp. (HM-1). The structures of the new compounds including their absolute configurations were elucidated by comprehensive spectroscopic methods and quantum E...

journal_title：Natural product research

authors： Yang WW,Lu LW,Zhang XQ,Bao SS,Cao F,Guo ZY,Deng ZS,Proksch P

更新日期：2020-09-30 00:00:00

abstract：:Aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. Here, we biosynthesised mosquitocidal silver nanoparticles (AgNP) using the aqueous leaf extract of Crotalaria verrucosa. The green synthesis of AgNP was studied by UV-vis spectroscopy, SEM, EDX and ...

journal_title：Natural product research

authors： Murugan K,Sanoopa CP,Madhiyazhagan P,Dinesh D,Subramaniam J,Panneerselvam C,Roni M,Suresh U,Nicoletti M,Alarfaj AA,Munusamy MA,Higuchi A,Kumar S,Perumalsamy H,Ahn YJ,Benelli G

更新日期：2016-01-01 00:00:00

abstract：:A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using 1H NMR, 13C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidat...

journal_title：Natural product research

authors： Yuan T,Zhang C,Qiu C,Xia G,Wang F,Lin B,Li H,Chen L

更新日期：2018-08-01 00:00:00

abstract：:Tectona grandis Linn (Teak), is locally known as Sagwan, belongs to Lamiaceae family. It is one of the most valuable timber in the world, due to its beautiful surface and its resistance to termite and fungal damage. The main active ingredient compounds that are responsible for these action are tectoquinone, lapachol a...

journal_title：Natural product research

authors： Vyas P,Yadav DK,Khandelwal P

更新日期：2019-08-01 00:00:00