Antifungal sesquiterpenes with post-harvest anthracnose control effect on bananas from the fungus Fusarium lateritium.

Abstract:

:To search for antifungal leads, the metabolites of an insect-derived fungus Fusarium lateritium ZMT01 were investigated, providing five sesquiterpenes (1-5), including new molecules microsphaeropsisins D and E (1 and 2). The evaluated antifungal activities in vitro which are higher than the positive control triadimefon include: 1 and 2 towards Fusarium oxysporum (MICs 50, 25 mg L-1; triadimefon 100 mg L-1); 1, 2, 4 and 5 towards Penicillium italicum (MICs 25, 12.5, 25, 25; triadimefon 50 mg L-1), 1, 2 and 4 towards Colletotrichum musae (MICs 25, 12.5, 25; triadimefon 80 mg L-1), 2 and 4 towards Fusarium graminearum (MICs 100, 100; triadimefon 150 mg L-1). The bioassay in vivo displayed that the banana anthracnose control effect of 2 (100 mg L-1) was also higher than that of triadimefon (Inhibition ratios 27.5 ± 2.5%, 55.3 ± 1.4%, 52.1 ± 1.3% for 2, 22.5 ± 2.1%, 47.2 ± 2.0%, 36.6 ± 2.2% for triadimefon at 4 d, 8 d and 12 d, respectively).

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Zhu J,Xiong P,Li Z,Li J,Lin L,Fu X,Huang Y,Xiong Y,Li C

doi

10.1080/14786419.2021.1872569

subject

Has Abstract

pub_date

2021-01-15 00:00:00

pages

1-8

eissn

1478-6419

issn

1478-6427

pub_type

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