A new β-tetralonyl glucoside from the Santalum album derived endophytic fungus Colletotrichum sp. GDMU-1.

Abstract:

:A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2-6) were isolated from a fungus Colletotrichum sp . GDMU-1 derived from the leaves of Santalum album. Their structures were determined by detailed analysis of spectroscopic data. All compounds were tested for the inhibitory effects on the nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW264.7 cells. Among them, compounds 4 and 5 showed moderate anti-inflammatory activity with IC50 value of 30.4 and 8.9 μM, respectively.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Liu W,Chen S,Li J,Yang X,Yan C,Liu H

doi

10.1080/14786419.2018.1452003

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

354-359

issue

3

eissn

1478-6419

issn

1478-6427

journal_volume

33

pub_type

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