Oleanane-type triterpene saponins from Aralia armata leaves and their cytotoxic activity.

abstract：:This study is designed to examine the chemical composition of the essential oil obtained from Buddleja thyrsoides Lam leaves from south Brazil. Gas chromatography/mass spectrometry analysis resulted in the detection of 12 components, representing 91.4% of the total oil composition. Germacrene D (27.16%), 1,10-di-epi-C...

journal_title：Natural product research

authors： Mahlke JD,Boligon AA,Machado MM,Athayde ML

更新日期：2013-01-01 00:00:00

abstract：:The subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant...

journal_title：Natural product research

authors： Surveswaran S,Cai YZ,Xing J,Corke H,Sun M

更新日期：2010-02-01 00:00:00

abstract：:Natural estrogens have demonstrated a wide variety of biological activities, which makes them a good candidate for the treatment of diabetes. In vitro, this study evidenced that isoflavones enhanced insulin secretion and inhibited α-amylase activity. In vivo, the findings indicated that soy isoflavones stimulated insu...

journal_title：Natural product research

authors： Hamden K,Jaouadi B,Carreau S,Aouidet A,Elfeki A

更新日期：2011-02-01 00:00:00

abstract：:This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...

journal_title：Natural product research

authors： Dias ALB,Batista HRF,Sousa WC,Bailão EFLC,Rocha JD,Sperandio EM,Fernandes CC,Souchie EL,Miranda MLD

更新日期：2020-11-09 00:00:00

abstract：:Chemical investigation of the Red Sea sponge Dragmacidon coccinea led to the isolation of a new nucleoside, dragmacidoside (1), along with eight known compounds: adenosine (2), inosine (3), deoxycytidine (4), methyl-α-d-glucopyranoside (5), clionasterol (6), stigmasterol (7), campesterol (8) and brassicasterol (9). Th...

journal_title：Natural product research

authors： Abou-Hussein DR,Badr JM,Youssef DT

更新日期：2014-01-01 00:00:00

abstract：:Okra, Abelmoschus esculentus L. (Moench), also known as Lady's Fingers, gombo, or bamje, is an annual plant belonging to the Malvaceae family. Traditional olistic medicine since centuries directly associates this plant and its parts to a beneficial health hypoglycemic effect. Since the abscisic acid (ABA) has been ass...

journal_title：Natural product research

authors： Daliu P,Annunziata G,Tenore GC,Santini A

更新日期：2020-01-01 00:00:00

abstract：:One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginos...

journal_title：Natural product research

authors： Xia X,Luo JG,Liu RH,Yang MH,Kong LY

更新日期：2016-10-01 00:00:00

abstract：:The aim of the study was comparing the chemical composition of the essential oils from five varieties of lavender (Lavandula angustifolia L.), and its biological activity against two pathogenic bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. In the comparison we included the following varieties: 'Munstead'...

journal_title：Natural product research

authors： Adaszyńska M,Swarcewicz M,Dzięcioł M,Dobrowolska A

更新日期：2013-01-01 00:00:00

abstract：:A facile, atom-economic synthesis of isoxazilidino withaferin, a novel hybrid of withaferin A, has been accomplished via two-step reaction of nitrone synthesis followed by nitrone 1,3-dipolar cycloaddition. The reaction is highly chemoselective (preferential reaction only on one of the two double bonds present on with...

journal_title：Natural product research

authors： Mandal R,Singh M,Krishnan AAV,Dahat YH,Bharitkar YP,Ravichandiran V,Hazra A

更新日期：2020-08-01 00:00:00

abstract：:The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was characterized as (3E, 6E, 10E)-8a-butoxy-17(15→14), 20(12→11)-bis-abeo-ce...

journal_title：Natural product research

authors： Chakraborty K,Salas S,Joy M

更新日期：2020-06-01 00:00:00

abstract：:This study showed for the first time the antioxidant and hypoglycaemic properties of the methanol, n-hexane and ethyl acetate extracts from Senecio stabianus Lacaita, a plant that belongs to the Asteraceae family. The antioxidant activities were carried out using two different in vitro assays, namely 2,2-diphenyl-1-pi...

journal_title：Natural product research

authors： Tundis R,Menichini F,Loizzo MR,Bonesi M,Solimene U,Menichini F

更新日期：2012-01-01 00:00:00

abstract：:A new protopine alkaloid, protomexicine and a new isoflavonoid, mexitin, together with 8-methoxydihydrosanguinarine, 13-oxoprotopine, rutin and quercetrin have been isolated from the aerial part of the methanolic extract of Argemone mexicana. The structures of these compounds have been established by various spectral ...

journal_title：Natural product research

authors： Singh S,Pandey VB,Singh TD

更新日期：2012-01-01 00:00:00

abstract：:A new β-hydroxydihydrochalcone glycoside named ziganin (1) and a new acylated flavonol glycoside named isorhamnetin-3-O-α-L-(2″,3″-di-O-trans-coumaroyl)-rhamnopyranoside) (2), along with two known flavonoid glycosides, a β-hydroxydihydrochalcone glycoside, a hydroxybenzoic acid derivative, a trinorguaiane type sesquit...

journal_title：Natural product research

authors： Özbek H,Güvenalp Z,Kuruüzüm-Uz AE,Kazaz C,Demirezer LÖ

更新日期：2016-01-01 00:00:00

abstract：:Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was s...

journal_title：Natural product research

authors： Miyazawa M,Kohno G,Okuno Y,Oda Y

更新日期：2006-06-01 00:00:00

abstract：:Antibacterial activities of prenylated xanthones from Garcinia mangostana and their synthetic analogues were investigated, and their structure-activity relationships have been studied. γ-Mangostin has shown antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphyl...

journal_title：Natural product research

authors： Dharmaratne HR,Sakagami Y,Piyasena KG,Thevanesam V

更新日期：2013-01-01 00:00:00

abstract：:Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were ev...

journal_title：Natural product research

authors： Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SH

更新日期：2019-04-10 00:00:00

abstract：:Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...

journal_title：Natural product research

authors： Spinelli R,Aimaretti FM,López JA,Siano AS

更新日期：2019-03-31 00:00:00

abstract：:The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...

journal_title：Natural product research

authors： Arain RA,Ahmad F,Khatri Z,Peerzada MH

更新日期：2021-01-01 00:00:00

abstract：:This work is an attempt to explore the anti-spermatogenic activity of Pistia stratiotes and to investigate it as a male contraceptive. The prepared extracts were screened for the presence of alkaloids, glycosides, steroids, flavonoids, saponin and phenolic compounds. To assess the anti-spermatogenic activity, mice wer...

journal_title：Natural product research

authors： Singh K,Dubey BK,Tripathi AC,Singh AP,Saraf SK

更新日期：2014-01-01 00:00:00

abstract：:One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2-5), together with eight alkaloids (6-13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds...

journal_title：Natural product research

authors： Diao HZ,Chen WH,Cao J,Shao TM,Song XP,Han CR

更新日期：2019-05-01 00:00:00

abstract：:Chronic administration of myricetin (100 and 300 mg kg⁻¹, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension and oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes and reversed th...

journal_title：Natural product research

authors： Borde P,Mohan M,Kasture S

更新日期：2011-09-01 00:00:00

abstract：:Three new diterpenoids, liquidambolide A (1) and liquiditerpenoic acids A (2) and B (3), together with 10 known diterpenes were isolated from the resin of Liquidambar formosana Hance, whose structures were elucidated by detailed analysis on the NMR and HR-ESI-MS spectra. ...

journal_title：Natural product research

authors： Shang HJ,Li DY,Wang WJ,Li ZL,Hua HM

更新日期：2014-01-01 00:00:00

abstract：:There has been growing interest in the research of flavonoids due to their potential antiviral activities. Recently, some natural flavonoids have shown potential inhibitory activity against zika virus NS3-NS2B protease. In order to accelerate the drug discovery efforts using flavonoids, a Monte Carlo simulation-based ...

journal_title：Natural product research

authors： Bhargava S,Patel T,Gaikwad R,Patil UK,Gayen S

更新日期：2019-03-01 00:00:00

abstract：:Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...

journal_title：Natural product research

authors： Guan F,Shan Y,Zhao X,Zhang D,Wang M,Peng F,Xia B,Feng X

更新日期：2011-02-01 00:00:00

abstract：:A megastigmane sulphoglycoside together with three phenolic compounds were isolated from the water-soluble fraction of the pericarps of Garcinia mangostana. The structure of the new compound was determined as 4-O-sulpho-β-d-glucopyranosyl abscisate (1) by spectroscopic data. Proanthocyanidin A2 (2) showed potent α-glu...

journal_title：Natural product research

authors： Tran TH,Le Huyen T,Tran TM,Nguyen TA,Pham TB,Nguyen Tien D

更新日期：2016-07-01 00:00:00

abstract：:In a previous study, we evaluated the maternal and fetal safety of antimalarial herb Artemisia annua with artemisinin yield of 1.09%. Here, we attempted to ascertain the contraceptive claim of A. annua. Sexually matured female Wistar rats (180-220 g) were allotted into four study groups of six rats each. The control g...

journal_title：Natural product research

authors： Abolaji AO,Eteng MU,Ebong PE,Dar A,Farombi EO,Choudhary MI

更新日期：2014-01-01 00:00:00

abstract：:The present study was aimed to isolate active constituents from Blumea axillaris (Lam.) DC (Asteraceae) against phytopathogenic fungi. Bioactivity guided fractionation of the successive n-hexane, chloroform and methanol extract led to the isolation of the monoterpene ester (4 R,5S)-4-hydroxy-7-tigloyloxycarvotanaceton...

journal_title：Natural product research

authors： Sivanandhan S,Pathalam G,Antony S,Michael GP,Balakrishna K,Boovaragamurthy A,Shirota O,Alwahibi MS,El-Shikh MS,Ignacimuthu S

更新日期：2020-10-16 00:00:00

abstract：:Lycopus europaeus L. leaves water extract (LEL) was subjected to phytochemical analysis, and evaluated for its antibacterial and antioxidant effects. Antibacterial activity testing was performed on Staphylococcus aureus clinical strains from catheter-related and skin infections by broth microdilution test. LEL showed ...

journal_title：Natural product research

authors： Fialová S,Slobodníková L,Veizerová L,Grančai D

更新日期：2015-01-01 00:00:00

abstract：:A new 24-membered macrolide, 5'-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insectici...

journal_title：Natural product research

authors： Cao H,Liu W,Chang Y,Chen H,Zhang Y,Xu W,Tao L

更新日期：2019-03-01 00:00:00

abstract：:Mangrove plants are endowed with various biologically active compounds which have potent antibacterial and antioxidant properties. In present study, a bioactivity-guided fractionation for antibacterial and antioxidant active metabolites from the twigs of Avicennia officinalis collected from Kuala Selangor Nature Park,...

journal_title：Natural product research

authors： Assaw S,Mohd Amir MIH,Khaw TT,Bakar K,Mohd Radzi SA,Mazlan NW

更新日期：2020-08-01 00:00:00