A bioanalytical approach of chemical composition, bioactivity and cytotoxicity of Berteroa incana L. herb.

abstract：:Plants endue a key role against illnesses caused by oxidative stress. These attributes are frequently associated with polyphenolic compounds. However, presence and concentration of secondary metabolites are affected by abiotic factors. The in vitro culture techniques can solve these drawbacks. Peppers can be a suitabl...

journal_title：Natural product research

authors： Fidemann T,de Araujo Pereira GA,Bossard Nascimento L,Moraes MC,Bertão MR,da Silva RMG,Fernández Núñez EG

更新日期：2018-05-01 00:00:00

abstract：:Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group...

journal_title：Natural product research

authors： Tang P,Lin HX,Yuan TH,Cui YM

更新日期：2019-12-01 00:00:00

abstract：:Chemical diversity is vital to antitubercular drug discovery as it ensures a novel bioactivity profile. Marine sponges have so far provided more than 1000 new bioactive molecules. Ethyl acetate extract of the marine sponge Dendrilla nigra on bioactivity-guided screening yielded three new compounds denigrins A-C, with ...

journal_title：Natural product research

authors： Murali Krishna Kumar M,Devilal Naik J,Satyavathi K,Ramana H,Raghuveer Varma P,Purna Nagasree K,Smitha D,Venkata Rao D

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to investigate mercury accumulation in some species, caught in Mediterranean Sea, in the period between May and December 2015, and to compare it to the presence of Anisakis parasites. The samples were examined by direct mercury analyzer (DMA-80) for their Hg levels. The metal concentration wa...

journal_title：Natural product research

authors： Graci S,Collura R,Cammilleri G,Buscemi MD,Giangrosso G,Principato D,Gervasi T,Cicero N,Ferrantelli V

更新日期：2017-05-01 00:00:00

abstract：:In this study, phytochemical composition, antioxidant, enzyme inhibition and cytotoxic activities of methanol and dichloromethane (DCM) extracts of Bougainvillea glabra (B. glabra) flowers were investigated. Methanol extract was found to have higher total bioactive contents and UHPLC-MS analysis of methanol extract re...

journal_title：Natural product research

authors： Saleem H,Htar TT,Naidu R,Zengin G,Ahmad I,Ahemad N

更新日期：2020-09-01 00:00:00

abstract：:In the context of our previous communication on phytochemical studies of the ethanolic extract of flowers of Alstonia scholaris of Pakistan origin, these have resulted in the isolation of two new triterpenoids. One is of the oleanane type, alstoprenyol, 3-β-hydroxy-28-β-acetoxy-5-olea triterpene (1), the other is of u...

journal_title：Natural product research

authors： Sultana N,Saify ZS,Saleem M,Kamal M

更新日期：2013-01-01 00:00:00

abstract：:To search for anti-diabetic and insulin-sensitising natural products, the effect on adipocyte differentiation was investigated by assessing fat accumulation in 3T3-L1 preadipocytes using Oil Red O staining. Fractionation and separation of n-hexane and CHCl₃ fractions of Morinda officinalis (Rubiaceae) using several ch...

journal_title：Natural product research

authors： Liu Q,Kim SB,Ahn JH,Hwang BY,Kim SY,Lee MK

更新日期：2012-01-01 00:00:00

abstract：:Four xanthones were isolated from Gentianopsis paludosa Ma and were identified by modern spectroscopic methods. Cytotoxicity of the four xanthones was tested on HepG2 cells and HL-60 cells by sulphorhodamine B (SRB) assay. Clonogenic survival assay, trypan blue exclusion method, AO/EB staining and DNA fragmentation as...

journal_title：Natural product research

authors： Ding L,Liu B,Zhang SD,Hou Q,Qi LL,Zhou QY

更新日期：2011-04-01 00:00:00

abstract：:A new isoflavone, 4'-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2'-dimethoxy-3',4...

journal_title：Natural product research

authors： Adem FA,Kuete V,Mbaveng AT,Heydenreich M,Koch A,Ndakala A,Irungu B,Yenesew A,Efferth T

更新日期：2019-09-01 00:00:00

abstract：:First total synthesis of carpatamide-A 7a, cytotoxic arylamine derivative isolated from marine derived Streptomyces sp., was achieved in twelve steps with overall yield of 24% with seven longest linear steps. In the penultimate step, dienoic acid 13 and an amino-phenylpropionic acid methyl ester core 21 were coupled t...

journal_title：Natural product research

authors： Burman RP,Gupta S,Bhatti J,Verma K,Rajak D,Gill MS

更新日期：2019-04-01 00:00:00

abstract：:The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...

journal_title：Natural product research

authors： Mengoni T,Peregrina DV,Censi R,Cortese M,Ricciutelli M,Maggi F,Di Martino P

更新日期：2016-01-01 00:00:00

abstract：:Investigation of the roots of Lotus polyphyllos Clarke resulted in the isolation of two new isoflavone derivatives; 4'-O-methylerythrinin C (3) and 4'-O-methyl-2''-hydroxydihydroalpinumisoflavone (4). In addition, the three known isoflavone derivatives 4'-O-methylalpinumisoflavone (1) lupinalbin F (5), 4',7-dimethoxy-...

journal_title：Natural product research

authors： Abdel-Kader MS,Amer ME,Tang S,Kingston DG

更新日期：2006-08-01 00:00:00

abstract：:Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

journal_title：Natural product research

authors： Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

更新日期：2019-09-30 00:00:00

abstract：:Oxygen radical absorbance capacity (ORAC) is a widely used hydrogen atom transfer-based method which measures the antioxidant capacity of natural products. ORAC values of oleaster (Elaeagnus angustifolia L.), which was extracted with ethanol/acetone (7:3, v/v), ethanol/water (1:1, v/v) and methanol/water (1:1, v/v) in...

journal_title：Natural product research

authors： Yalcin G,Sogut O

更新日期：2014-01-01 00:00:00

abstract：:Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...

journal_title：Natural product research

authors： Komala I,Rahmani M,Sukari MA,Mohd Ismail HB,Cheng Lian GE,Rahmat A

更新日期：2006-04-01 00:00:00

abstract：:Okra, Abelmoschus esculentus L. (Moench), also known as Lady's Fingers, gombo, or bamje, is an annual plant belonging to the Malvaceae family. Traditional olistic medicine since centuries directly associates this plant and its parts to a beneficial health hypoglycemic effect. Since the abscisic acid (ABA) has been ass...

journal_title：Natural product research

authors： Daliu P,Annunziata G,Tenore GC,Santini A

更新日期：2020-01-01 00:00:00

abstract：:Excessive accumulation of iron in the body can lead to organ injury. Some flavonoids which possess high affinity to iron can be used as iron chelators for curing iron overload diseases such as haemochromatosis. In this article, the effects of baicalin and quercetin on different mouse tissues (liver, kidney and heart) ...

journal_title：Natural product research

authors： Zhang Y,Gao Z,Liu J,Xu Z

更新日期：2011-07-01 00:00:00

abstract：:From the fruiting body of ectomycorrhizal fungi Cortinarius xiphidipus, sterols were identified from the crude extract and the cytotoxic effect of ergosta-4, 6, 8(14), 22-tetraen-3-one (ergone) was evaluated. Ten sterols including ergosta-3,5,7,9(11),22-pentaene, (22E)-ergosta-5,7,9(11),22-tetraen-3b-ol, (3β,22E)-ergo...

journal_title：Natural product research

authors： Torres S,Cajas D,Palfner G,Astuya A,Aballay A,Pérez C,Hernández V,Becerra J

更新日期：2017-02-01 00:00:00

abstract：:Three compounds, toosendanin (1), kulactone (2) and scopoletin (3), were isolated from either the root bark and/or the stem bark of Melia volkensii. Their structures were determined on the basis of spectroscopic data generated and by comparison with data from the literature. 1 and 2, isolated for the first time from M...

journal_title：Natural product research

authors： Kamau RW,Juma BF,Baraza LD

更新日期：2016-09-01 00:00:00

abstract：:The chemical composition of the volatile concentrate prepared by supercritical CO(2) extraction of the needles of Pinus nigra Arnold ssp. laricio Poiret from Corsica was investigated using GC (RI), GC-MS and (13)C NMR spectroscopy. The major component was by far manoyl oxide (63%), a compound of potential interest for...

journal_title：Natural product research

authors： Duquesnoy E,Marongiu B,Castola V,Piras A,Porcedda S,Casanova J

更新日期：2007-07-20 00:00:00

abstract：:Flavonoids have always attracted much attention due to their reversal activity on multidrug resistance (MDR). Eight flavonoids isolated from traditional Chinese medicine Sophora alopecuroides L. were applied to test their effect on MDR associated protein 1 (MRP1) through the established predicting assay. Three flavono...

journal_title：Natural product research

authors： Ni K,Yang L,Wan C,Xia Y,Kong L

更新日期：2014-01-01 00:00:00

abstract：:Aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. Here, we biosynthesised mosquitocidal silver nanoparticles (AgNP) using the aqueous leaf extract of Crotalaria verrucosa. The green synthesis of AgNP was studied by UV-vis spectroscopy, SEM, EDX and ...

journal_title：Natural product research

authors： Murugan K,Sanoopa CP,Madhiyazhagan P,Dinesh D,Subramaniam J,Panneerselvam C,Roni M,Suresh U,Nicoletti M,Alarfaj AA,Munusamy MA,Higuchi A,Kumar S,Perumalsamy H,Ahn YJ,Benelli G

更新日期：2016-01-01 00:00:00

abstract：:Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

journal_title：Natural product research

authors： Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

更新日期：2017-05-01 00:00:00

abstract：:Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...

journal_title：Natural product research

authors： Hou SQ,Li YH,Huang XZ,Li R,Lu H,Tian K,Ruan RS,Li YK

更新日期：2017-11-01 00:00:00

abstract：:The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fisc...

journal_title：Natural product research

authors： Bruno M,Fiori M,Mattei D,Melchiorre S,Messineo V,Volpi F,Bogialli S,Nazzari M

更新日期：2006-07-20 00:00:00

abstract：:Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their...

journal_title：Natural product research

authors： Xu J,Hu Q,Ding W,Wang P,Di Y

更新日期：2018-04-01 00:00:00

abstract：:The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...

journal_title：Natural product research

authors： Lee CL,Liao KC,Chen CC,Lin YA,Wu TY,Jhan YL,Chen CJ,Yang JC,Wu YC

更新日期：2019-07-30 00:00:00

abstract：:Ocimum is a genus of aromatic herbs, undershurbs or shrubs distributed in the tropical and warm temperate regions of the world. Larvicidal activity of essential oils and different extracts of O. sanctum, O. basilicum and O. gratissimum were compared on laboratory reared and field collected larvae of Culex quinquefasci...

journal_title：Natural product research

authors： Rajamma AJ,Dubey S,Sateesha SB,Tiwari SN,Ghosh SK

更新日期：2011-12-01 00:00:00

abstract：:Two new C13-norsesquiterpenes claulanterpene A (1) and B (2), together with two known sesquiterpenes (3-4), were isolated from methanol extract of the stem and leaf of Clausena lansium collected from Qingyuan county, Guangdong Province, China. Their structures were elucidated on the base of extensive spectroscopic ana...

journal_title：Natural product research

authors： Liu XY,Fu XX,Li YY,Xiong ZH,Li BT,Peng WW

更新日期：2020-03-25 00:00:00

abstract：:A new HPLC-DAD method was developed and validated for simultaneous determination of six main phenylethanoid glycosides (calceolarioside D, neocalceolarioside D, verbascoside, isoverbascoside, leucoseptoside A and martynoside) in the aerial parts of four Scutellaria L. taxa from flora of Turkey. All standard compounds ...

journal_title：Natural product research

authors： Bardakci H,Türköz Acar E,Kırmızıbekmez H

更新日期：2019-07-01 00:00:00