Oleanane triterpenoids from Rubia philippinensis and their inhibitory effect on 20-HETE synthesis.

Abstract:

:A new oleanane triterpenoid (2) was isolated from the roots of Rubia philippinensis. The structure of 2 was determined by analysis of HRMS and NMR data and identified as a rubiprasin analogue, 16β-hydroxyrubiprasin B. Four related known compounds were also encountered which include rubiprasin B (1), maslinic acid (3), 4-epi-hederagenin (4) and oleanolic acid (5). The compounds 3-5 displayed moderate inhibitory activity against the synthesis of the eicosanoid 20-HETE.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Quan KT,Min BG,Hwang IH,Choi YJ,Kim SK,Na M

doi

10.1080/14786419.2019.1645656

subject

Has Abstract

pub_date

2019-07-25 00:00:00

pages

1-7

eissn

1478-6419

issn

1478-6427

pub_type

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