The comparison of DPPH-scavenging capacity and anti-inflammatory effects of phenolic compounds isolated from the stems of Stewartia koreana Nakai.

Abstract:

:The Stewartia koreana Nakai (SK) had been used in oriental traditional medicine as a remedy for acute gastroenteritis, liver diseases, quadriplegia and pain. The antioxidant activity guided isolation 80% methyl extract from stems of SK yielded eight phenolic compounds. We evaluated the anti-oxidative and anti-inflammatory effects of these compounds via assays of 1,1-diphenyl-2-picrylhydazyl (DPPH) radicals and inhibition of nitric oxide (NO) production in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. The results demonstrated that syringaresinol (6) exhibited significant DPPH radical-scavenging activity and inhibitory effects on NO production compared with its positive controls, ascorbic acid and L-NMMA, respectively.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Kim MH,Jang JH,Oh MH,Heo JH,Lee MW

doi

10.1080/14786419.2014.905560

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

1409-12

issue

17

eissn

1478-6419

issn

1478-6427

journal_volume

28

pub_type

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