Mediterranean shrubs as potential antioxidant sources.

abstract：:Two new polyketides, purpurofuranone (1) and purpuropyranone (2), were isolated along with the known polyketides, cillifuranone (3) and taiwapyrone (4), from a mutant BD-3n-1 derived from the diethyl sulfate (DES) mutagenesis of a marine-derived Penicillium purpurogenum G59. The structures of 1 and 2 were elucidated b...

journal_title：Natural product research

authors： Wu CJ,Qiao H,Cui CB,Yang Y,Xu R,Sun CX,Li DH,Li CW

更新日期：2019-10-01 00:00:00

abstract：:New sesquiterpene glycoside, cyclodipeptide and piperidine derivative were isolated from Streptomyces sp. YIM 63342. On the basis of spectral data, their structures were determined as 3R, 5R, 6S, 7E, 9R-megastigman-7-en-3,5,6,9-tetrol-9-O-β-D-apiofuranosyl-(1→ 2)-β-D-glucopyranoside (1), cyclo (L-Pro-L-OMet) (2) and (...

journal_title：Natural product research

authors： Yang XQ,Yang YB,Zhou H,He GW,Zhao LX,Xu LH,Ding ZT

更新日期：2013-01-01 00:00:00

abstract：:Three Ballota species, Ballota undulata, Ballota saxatilis and Ballota nigra ssp. foetida, were investigated for their cytotoxicity against two human cancer cells, hepatoma HepG2 cell line and breast cancer MCF-7 cell line, and for their antioxidant activity. The chemical composition of essential oils was studied by G...

journal_title：Natural product research

authors： Rigano D,Marrelli M,Formisano C,Menichini F,Senatore F,Bruno M,Conforti F

更新日期：2017-02-01 00:00:00

abstract：:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...

journal_title：Natural product research

authors： Balas L,Hellal M,Rossi JC,Durand T

更新日期：2005-06-01 00:00:00

abstract：:Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...

journal_title：Natural product research

authors： Orsi RO,Fernandes A Jr,Bankova V,Sforcin JM

更新日期：2012-01-01 00:00:00

abstract：:Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their ...

journal_title：Natural product research

authors： Li W,Tang GH,Chen L,Tang YQ,Xu YK,Liu B,Yin S

更新日期：2018-07-01 00:00:00

abstract：:The hexane fraction from the roots of Echinops ellenbeckii O. Hoffm. from Ethiopia yielded seven acetylenic thiophenes of which five compounds (1, 3, 4, 6, 7) are reported for the first time in this species: the monothiophenes 5-(penta-1,3-diynyl)-2-(but-3-en-1-ynyl)-thiophene (1), 5-(penta-1,3-diynyl)-2-(4-acetoxy-bu...

journal_title：Natural product research

authors： Hymete A,Rohloff J,Kjøsen H,Iversen TH

更新日期：2005-12-01 00:00:00

abstract：:Essential oils derived from six different phenophases, namely early vegetative stage, late vegetative stage, early flowering stage, full flowering stage (FFS), late flowering stage and seed shattering stage of Origanum vulgare L. grown in Kumaon region of Uttarakhand, India were investigated by GC and GC-MS. A total o...

journal_title：Natural product research

authors： Verma RS,Padalia RC,Chauhan A

更新日期：2012-01-01 00:00:00

abstract：:The phytochemical study of the aerial parts of Viburnum chinshanense Graebn., a species growing in Western and Central China, led to the isolation of six iridoid glucosides: the novel 10,2'-diacetylpatrinoside, 1, and the known 2'-acetyldihydropenstemide, 2'-trans- p-coumaroyl-dihydropenstemide, 2'-acetylpatrinoside, ...

journal_title：Natural product research

authors： Tomassini L,Gao J,Foddai S,Serafini M,Ventrone A,Nicoletti M

更新日期：2006-07-10 00:00:00

abstract：:The leaves of Alchornea floribunda and Alchornea cordifolia are used traditionally as topical anti-inflammatory agents. In this study, two highly lipophilic fractions AFLF and ACLF isolated from A. floribunda and A. cordifolia leaves respectively were investigated for topical anti-inflammatory effects using xylene-ind...

journal_title：Natural product research

authors： Okoye FB,Osadebe PO,Nworu CS,Okoye NN,Omeje EO,Esimone CO

更新日期：2011-12-01 00:00:00

abstract：:This study is designed to examine the chemical composition of the essential oil obtained from Buddleja thyrsoides Lam leaves from south Brazil. Gas chromatography/mass spectrometry analysis resulted in the detection of 12 components, representing 91.4% of the total oil composition. Germacrene D (27.16%), 1,10-di-epi-C...

journal_title：Natural product research

authors： Mahlke JD,Boligon AA,Machado MM,Athayde ML

更新日期：2013-01-01 00:00:00

abstract：:Alkylglycerols (AKGs) are bioactive natural compounds that vary by alkyl chain length and degree of unsaturation, and their absolute configuration is 2S. Three AKGs (5l-5n) were synthesised in enantiomerically pure form, and were characterised for the first time together with 12 other known and naturally occurring AKG...

journal_title：Natural product research

authors： Fernández Montoya DJ,Contreras Jordan LA,Moreno-Murillo B,Silva-Gómez E,Mayorga-Wandurraga H

更新日期：2019-11-04 00:00:00

abstract：:In this study the antioxidant and cytotoxicity activity of the Adonidia merrillii fruits were investigated using different solvent polarities (methanol, ethyl acetate and water). The results showed that the total phenolic and flavonoid contents of the methanolic extract was higher compare with other extract with respe...

journal_title：Natural product research

authors： Vafaei A,Bin Mohamad J,Karimi E

更新日期：2019-09-01 00:00:00

abstract：:In our continuous search for cytotoxic compounds from the genus Zanthoxylum, chromatographic separation of the MeOH/CH2Cl2 (1:1) extract of Z. chalybeum yielded one new alkamide; 4-(isoprenyloxy)-3-methoxy-3,4-deoxymethylenedioxyfagaramide (1) and a known one; fagaramide (2). Similarly, from the MeOH/CH2Cl2 (1:1) extr...

journal_title：Natural product research

authors： Omosa LK,Mbogo GM,Korir E,Omole R,Seo EJ,Yenesew A,Heydenreich M,Midiwo JO,Efferth T

更新日期：2019-03-21 00:00:00

abstract：:Two new eremophilanolides, sibiriolides A (1) and B (2), were isolated from the aerial parts of Xanthium sibiricum. The structures of the new compounds were identified as 4S,5R,7R,8R, 11R-2-oxo-1(10)-eremophilen-12,8-olide (1) and 4S,5R,7R,8R,11S-2-oxo-1(10)-eremophilen-12,8-olide (2) by HREIMS and NMR spectroscopic t...

journal_title：Natural product research

authors： Zhang XQ,Ye WC,Jiang RW,Yin ZQ,Zhao SX,Mak TC,Yao XS

更新日期：2006-11-01 00:00:00

abstract：:Chronic administration of myricetin (100 and 300 mg kg⁻¹, p.o., for 4 weeks) isolated from Vitis vinifera (Vitaceae) ameliorated hypertension and oxidative stress induced by deoxycorticosterone acetate (DOCA)-salt in rats. Myricetin treatment reduced systolic blood pressure, vascular reactivity changes and reversed th...

journal_title：Natural product research

authors： Borde P,Mohan M,Kasture S

更新日期：2011-09-01 00:00:00

abstract：:Fourteen N,N'-diaryl unsymmetrically substituted thioureas were synthesised and their cytotoxic (in vitro), phytotoxic (in vitro), acetylcholinesterase and butrylcholinesterase activities were determined. Thiourea 16 exhibited high, and 1 and 3 showed significant phytotoxic activity. Thioureas 1, 3, 4, 6 and 10 showed...

journal_title：Natural product research

authors： Begum S,Choudhary MI,Khan KM

更新日期：2009-01-01 00:00:00

abstract：:A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), β-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the et...

journal_title：Natural product research

authors： Quang DN,So TC,Thanh NTP,Hoa LTP,Dien PH,Luong TM,Tung NQ,Long LD,Dai TD,Tien NQ

更新日期：2018-04-01 00:00:00

abstract：:A new phenolic glycoside, methylpicraquassioside B (6), together with nine known glycosides, cnidioside A (1), cnidioside B (2), picraquassioside A (3), methylpicraquassioside A (4), picraquassioside B (5), xanthotoxol-8-β-glucoside (7), 5-methoxy-xanthotoxol-8-β-glucoside (8), 8-methoxy-xanthotoxol-5-β-glucoside (9) ...

journal_title：Natural product research

authors： Kim SB,Chang BY,Han SB,Hwang BY,Kim SY,Lee MK

更新日期：2013-01-01 00:00:00

abstract：:Chromatographic purification of the DCM sub-extract of Uvaria grandiflora led to the isolation and characterization of a new polyoxygenated cyclohexane derivative, grandifloranol (1), together with five known compounds. Among the compounds isolated, zeylenone (3) showed moderate antitubercular activity against Mycobac...

journal_title：Natural product research

authors： Macabeo APG,Flores AIG,Fernandez RAT,Budde S,Faderl C,Dahse HM,Franzblau SG

更新日期：2020-03-23 00:00:00

abstract：:Two new ent-atisanes ent-1β,3β,16β,17-tetrahydroxyatisane (1), ent-1β,3α,16β,17-tetrahydroxyatisane (2) together with 11 known diterpenes were isolated from the anti-tumour activity fraction of Euphorbia fischeriana Steud. The compounds were identified by detailed spectroscopic analysis, including extensive 2D-NMR exp...

journal_title：Natural product research

authors： Wang M,Wang Q,Wei Q,Li J,Guo C,Yang B,Kuang H

更新日期：2016-01-01 00:00:00

abstract：:Two new sesquiterpenoid glycosides as dihydrophaseic acid 4'-O-[6″-O-(4″'-hydroxy-3″', 5″'-dimethoxy) benzoyl)]-β-D-glucopyranoside (1) and dihydrophaseic acid 4'-O-[6″-O-(3″'-methoxy- 4″'-hydroxy) benzoyl)]-β-D-glucopyranoside (2), were isolated from the stems of Zanthoxylum armatum in the study. The compound 1 and 2...

journal_title：Natural product research

authors： Liu YL,Gao LL,Song TT,Guo T,Chang J

更新日期：2020-11-01 00:00:00

abstract：:The chemical composition and antioxidant activities of the essential oil from Nandina domestica fruits were studied for the first time. Twenty-two compounds, representing 82.79% of the oil, were identified from the oil. The major compounds were 3-hexen-1-ol (12.9%), linalool (12.3%), 2-methoxy-4-vinylphenol (9.9%), ol...

journal_title：Natural product research

authors： Bi SF,Zhu GQ,Wu J,Li ZK,Lv YZ,Fang L

更新日期：2016-01-01 00:00:00

abstract：:One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2-5), together with eight alkaloids (6-13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds...

journal_title：Natural product research

authors： Diao HZ,Chen WH,Cao J,Shao TM,Song XP,Han CR

更新日期：2019-05-01 00:00:00

abstract：:A new diterpenoid glycoside, 14,15-dinor-labdan-13-one-8-O-alpha-L-arabinopyranoside (1), was isolated from Conyza blinii. The structure of this new arabinoside was elucidated on the basis of extensive NMR and HRMS spectroscopy. In addition, the presence of 3R-hydroxyoctadecanoic acid in C. blinii was reported for the...

journal_title：Natural product research

authors： Su Y,Chen L,Wang D,Chai X,Guo D

更新日期：2008-04-15 00:00:00

abstract：:Extracts from three Calophyllum species endemic to Sri Lanka were tested for antifungal and antioxidant activities. Of them, only the root methanol extract of Calophyllum thwaitesii showed activity, and the active extract on activity guided fractionation yielded four antifungal active and three inactive xanthones. Ant...

journal_title：Natural product research

authors： Dharmaratne HR,Napagoda MT,Tennakoon SB

更新日期：2009-01-01 00:00:00

abstract：:Phebaclavin I, a novel 3-prenylated coumarin, was isolated from the aerial parts of Phebalium aff. tuberculosum (Rutaceae) together with five known related compounds, Phebaclavin A, B, D, G, H. The structure of phebaclavin I was established by spectroscopic methods. Several other known coumarins were obtained, includi...

journal_title：Natural product research

authors： Roux D,Muyard F,Girard C,Colombain M,Tillequin F,Waterman PG,Bévalot F

更新日期：2006-03-01 00:00:00

abstract：:The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-...

journal_title：Natural product research

authors： Wangensteen H,Phan TT,Rise F,Halvorsen TG,Malterud KE

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study is to estimate the nutritive values, metabolites of Hass and Reed Avocado cultivars and evaluate their antimicrobial and anticancer activities. Hass was rich in water soluble vitamins, iron and calcium while, Reed contains more fat soluble vitamins. Benzaldehyde and butyl phenol derivatives were ...

journal_title：Natural product research

authors： Younis IY,Hifnawy MS,El-Hawary SS,El Bishbishy MH,Elateek SY

更新日期：2020-09-11 00:00:00

abstract：:Toxicity of the pesticide carbofuran (CF) can be alleviated by curcumin, if not for its poor bioavailability. Hence, we investigated the effect of a bioavailable curcumin-galactomannan complex (CGM) on CF-induced neurotoxicity in rats in comparison to that of unformulated standard curcumin (CS). The CF (5 mg/kg b.wt/d...

journal_title：Natural product research

authors： E R S,P P B,Nair SS,Maliakel B,Kuttan R,I M K

更新日期：2020-05-01 00:00:00