Abstract:
:The chloroplast signal recognition particle (cpSRP) consists of a conserved 54 kDa subunit (cpSRP54) and a unique 43 kDa subunit (cpSRP43) but lacks SRP-RNA, an essential and universally conserved component of cytosolic SRPs. High sequence similarity exists between cpSRP54 and bacterial SRP54 except for a plant-specific C-terminal extension containing the cpSRP43-binding motif. We found that cpSRP54 of higher plants lacks the ability to bind SRP-RNA because of two amino acid substitutions within a region corresponding to the RNA binding domain of cytosolic SRP54, whereas the C-terminal extension does not affect RNA binding. Phylogenetic analysis revealed that these mutations occur in the cpSRP54 homologues of higher plants but not in most algae.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Richter CV,Träger C,Schünemann Ddoi
10.1016/j.febslet.2008.08.014subject
Has Abstractpub_date
2008-09-22 00:00:00pages
3223-9issue
21-22eissn
0014-5793issn
1873-3468pii
S0014-5793(08)00696-0journal_volume
582pub_type
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