Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.

abstract：:Adult rats have been phenotyped as high (HRs) or low (LRs) responders to novelty, the former associated with high-risk behaviors. Data indicating that adolescent rodents exhibit increased novelty-seeking relative to adults are equivocal, and phenotypic variations in adolescent novel stimulus reactivity are unknown. To...

journal_title：Behavioral neuroscience

authors： Philpot RM,Wecker L

更新日期：2008-08-01 00:00:00

abstract：:Previous electrophysiological studies and computational modeling suggest the hypothesis that cholinergic neuromodulation may reduce olfactory associative interference during learning (M. E. Hasselmo, B. P. Anderson, & J. M. Bower, 1992; M. E. Hasselmo & J. M. Bower, 1993). These results provide behavioral evidence sup...

journal_title：Behavioral neuroscience

authors： De Rosa E,Hasselmo ME

更新日期：2000-02-01 00:00:00

abstract：:The context preexposure facilitation effect (CPFE) is a variant of contextual fear conditioning in which context learning, context-shock association, and expression of context conditioning occur in 3 separate phases-preexposure, training, and testing. During the preexposure phase, the CPFE is disrupted by hippocampal ...

journal_title：Behavioral neuroscience

authors： Robinson-Drummer PA,Dokovna LB,Heroux NA,Stanton ME

更新日期：2016-04-01 00:00:00

abstract：:Classical conditioning of the rabbit eyeblink response was used to study the effects of cerebellar lesions on performance in animals trained with low-intensity unconditioned stimuli (US). Animals were trained with 1 of 2 low-intensity corneal-airpuff USs paired with a tone-conditioned stimulus. This study confirms ear...

journal_title：Behavioral neuroscience

authors： Ivkovich D,Lockard JM,Thompson RF

更新日期：1993-06-01 00:00:00

abstract：:Previous findings are discordant regarding the effects of perinatal lesions of Cortical Areas 17 and 18 on visual discrimination learning in cats. Three potential determinants of such sparing were investigated: age at lesion (4 or 181 days), age at testing (3 or 9 months), and stimulus complexity. Age at testing was n...

journal_title：Behavioral neuroscience

authors： Cornwell P,Herbein S,Corso C,Eskew R,Warren JM,Payne B

更新日期：1989-12-01 00:00:00

abstract：:In 2 experiments, the development of adjuvant arthritis (an experimental autoimmune disease) was inhibited by exposing rats to a flavored solution that had previously been paired with injections of cyclosporine (an immunodepressive drug) compared with rats with the same history but exposed to a flavored solution that ...

journal_title：Behavioral neuroscience

authors： Klosterhalfen S,Klosterhalfen W

更新日期：1990-10-01 00:00:00

abstract：:The present study examined the effects of lesions of the central nucleus of the amygdala (CeA) on the acquisition of a new response with conditioned reinforcement (CR) and its potentiation by intra-accumbens infusions of d-amphetamine (1, 3, 10, and 20 microg/microl). Rats were trained to associate a light-plus-noise ...

journal_title：Behavioral neuroscience

authors： Robledo P,Robbins TW,Everitt BJ

更新日期：1996-10-01 00:00:00

abstract：:It is widely believed that male mammals have better spatial ability than females. A large number of evolutionary hypotheses have been proposed to explain these differences, but few species have been tested. The authors critically review the proposed evolutionary explanations for sex differences in spatial cognition an...

journal_title：Behavioral neuroscience

authors： Jones CM,Braithwaite VA,Healy SD

更新日期：2003-06-01 00:00:00

abstract：:A learning event can be dissociated into 3 components: acquisition, storage, and recall. When the laboratory wild-type strain of Caenorhabditis elegans (N2 strain) is exposed to benzaldehyde in the absence of food, the worms display a reduction of their attractive response to this volatile odorant. This results from t...

journal_title：Behavioral neuroscience

authors： Atkinson-Leadbeater K,Nuttley WM,van der Kooy D

更新日期：2004-12-01 00:00:00

abstract：:This study was performed with male rats categorized as sexually naive (SN), sexually active (SA), or sexually inactive (SI). In a first experiment the effects of dopamine (DA) D2 agonist SND 919 (0.05, 1, and 10 mg/kg) on the copulatory behavior of SN, SA and SI rats were assessed. In a second experiment the DA D2 ago...

journal_title：Behavioral neuroscience

authors： Giuliani D,Ferrari F

更新日期：1996-08-01 00:00:00

abstract：:Modification of acoustic startle amplitude by a 10-ms tone prepulse (S1) was evaluated as a function of the interstimulus interval (ISI) between the onset of S1 and the onset of the startle-evoking stimulus (S2). Subjects were normal-hearing 1-month-old C57BL/6J (C57) mice and CBA/CaJ mice and 5-month-old C57 mice wit...

journal_title：Behavioral neuroscience

authors： Willott JF,Carlson S

更新日期：1995-06-01 00:00:00

abstract：:The effects of dl-cathinone on milk intake and motor activity were investigated in bottle- and cannula-fed rats. Acute injections of cathinone produced dose-dependent increases in activity in both groups but only produced decreased intake in bottle-fed rats. With chronic injections, tolerance to the suppression of int...

journal_title：Behavioral neuroscience

authors： Wolgin DL,Munoz JR

更新日期：2006-04-01 00:00:00

abstract：:The aim of this study was to investigate the effects of postnatal choline supplementation on neurochemical and behavioral parameters in preweanling BALB/cByJ mice. Mouse pups were injected daily subcutaneously with choline chloride (0.85 mM/g body weight) from Postnatal Day (PND) 1 to PND 16. Pups performed a passive ...

journal_title：Behavioral neuroscience

authors： Ricceri L,Berger-Sweeney J

更新日期：1998-12-01 00:00:00

abstract：:To examine whether the hippocampus is required for memory for unique experiences independent of their spatial or temporal context, the authors devised a novel task that requires rats to remember odor-reward associations formed within a single training trial. Unlike previous tests of 1-trial memory, in this task new as...

journal_title：Behavioral neuroscience

authors： Wood ER,Agster KM,Eichenbaum H

更新日期：2004-06-01 00:00:00

abstract：:Neural correlates of associative memory and "forgetting" were observed 1, 6, and 14 days after acquisition of a conditioned response (CR) in the marine snail Hermissenda. Behavioral expression of a light-rotation association, as indexed by contraction of the animal's foot in response to light, dissipated throughout th...

journal_title：Behavioral neuroscience

authors： Matzel LD,Collin C,Alkon DL

更新日期：1992-12-01 00:00:00

abstract：:The medial division of the medial geniculate body (MGm) projects to the lateral amygdala and the upper layer of auditory cortex and develops physiological plasticity rapidly during classical conditioning. The effects of learning on frequency receptive fields (RFs) in the MGm of the guinea pig have been determined. Cla...

journal_title：Behavioral neuroscience

authors： Edeline JM,Weinberger NM

更新日期：1992-02-01 00:00:00

abstract：:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexp...

journal_title：Behavioral neuroscience

authors： Holland PC,Gallagher M

更新日期：1993-04-01 00:00:00

abstract：:The common assumption that perceptual sensitivities are related to neural representations of sensory stimuli has seldom been directly demonstrated. The authors analyzed the similarity of spike trains evoked by complex sounds in the rat auditory cortex and related cortical responses to performance in an auditory task. ...

journal_title：Behavioral neuroscience

authors： Orduña I,Mercado E 3rd,Gluck MA,Merzenich MM

更新日期：2005-02-01 00:00:00

abstract：:Four experiments studied the opioid receptor subtype and signal transduction mechanisms mediating fear extinction in the ventrolateral quadrant of the midbrain periaqueductal gray (vlPAG). Microinjection of a mu- but not a delta- or kappa-opioid receptor antagonist into the vlPAG retarded extinction. Extinction was al...

journal_title：Behavioral neuroscience

authors： McNally GP,Lee BW,Chiem JY,Choi EA

更新日期：2005-08-01 00:00:00

abstract：:Rats with perirhinal cortex lesions were sequentially trained in a rectangular water tank on a series of 3 visual discriminations, each between mirror-imaged stimuli. When these same discriminations were tested concurrently, the rats were forced to use a configural strategy to solve the problems effectively. There was...

journal_title：Behavioral neuroscience

authors： Aggleton JP,Albasser MM,Aggleton DJ,Poirier GL,Pearce JM

更新日期：2010-02-01 00:00:00

abstract：:The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...

journal_title：Behavioral neuroscience

authors： Epstein LH,Temple JL,Neaderhiser BJ,Salis RJ,Erbe RW,Leddy JJ

更新日期：2007-10-01 00:00:00

abstract：:Appetitive behaviors of rats were monitored in a runway situation following central infusions of neuroactive substances into brain areas implicated in electrical self-stimulation. Microinjections of the dopamine antagonist cis-flupentixol or the cholinergic antagonist atropine into the nucleus accumbens (Acb) severely...

journal_title：Behavioral neuroscience

authors： Ikemoto S,Panksepp J

更新日期：1996-04-01 00:00:00

abstract：:Mapping studies were conducted to delineate the site(s) of action for the arousal-enhancing actions of norepinephrine (NE) within the basal forebrain region encompassing the medial preoptic area (MPOA) and the substantia innominata (SI). Varying doses of NE, the beta-agonist, isoproterenol, or the alpha1-agonist, phen...

journal_title：Behavioral neuroscience

authors： Berridge CW,O'Neill J

更新日期：2001-02-01 00:00:00

abstract：:The rat's willingness to ingest glucose after an initial intraoral intake test was probed by beginning a 2nd intraoral intake test at variable durations (1-120 min). In Experiment 1, after an initial meal of 12.5% glucose solution averaging 26.9 +/- 1.7 ml (SEM, n = 10), the size of the 2nd (probe) meal of the same st...

journal_title：Behavioral neuroscience

authors： Kaplan JM,Seeley RJ,Grill HJ

更新日期：1994-04-01 00:00:00

abstract：:Norway rat pups were either handled (H) or undisturbed (nonhandled, NH) in the period between birth and weaning on Day 21. Following weaning, half of the animals in each group were housed socially (Soc), and half were housed in isolation (Isol). At 120-150 days of age, all animals were sacrificed, and the following re...

journal_title：Behavioral neuroscience

authors： Meaney MJ,Aitken DH,Bodnoff SR,Iny LJ,Tatarewicz JE,Sapolsky RM

更新日期：1985-08-01 00:00:00

abstract：:The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent m...

journal_title：Behavioral neuroscience

authors： Kilpatrick L,Cahill L

更新日期：2003-02-01 00:00:00

abstract：:Four rhesus monkeys (Macaca mulatta) were trained to learn novel sets of visuomotor associations in 50 trials or less, within single test sessions. After bilateral ablation of the orbital and ventral prefrontal cortex, the monkeys lost the ability to learn these associations within a session, although they could learn...

journal_title：Behavioral neuroscience

authors： Bussey TJ,Wise SP,Murray EA

更新日期：2001-10-01 00:00:00

abstract：:A microstructural analysis of the licking behavior of the rat was used to investigate the effects of total abdominal vagotomy on ingestive behavior. Vagotomy decreased the meal size of milk and 3 concentrations of sucrose. The decrease was due to an increase in the decline in the rate of licking during the meal, sugge...

journal_title：Behavioral neuroscience

authors： Davis JD,Smith GP,Kung TM

更新日期：1994-08-01 00:00:00

abstract：:Studies have shown that ovarian hormones protect against some of the cognitive deficits associated with aging. Although much of the literature in rodents has focused on hippocampal dependent tasks, studies suggest that tasks dependent on the prefrontal cortex are also influenced by ovarian hormones. The present study ...

journal_title：Behavioral neuroscience

authors： Chisholm NC,Juraska JM

更新日期：2012-02-01 00:00:00

abstract：:Social interaction may elicit aggression, establish social rank, and be influenced by changes in central dopaminergic activity. In the lizard Anolis carolinensis, a sign stimulus (darkening of postorbital skin or eyespots) inhibits aggressive response from opponents, in part because it forms more rapidly in dominant m...

journal_title：Behavioral neuroscience

authors： Korzan WJ,Forster GL,Watt MJ,Summers CH

更新日期：2006-02-01 00:00:00