Abstract:
:The effects of dl-cathinone on milk intake and motor activity were investigated in bottle- and cannula-fed rats. Acute injections of cathinone produced dose-dependent increases in activity in both groups but only produced decreased intake in bottle-fed rats. With chronic injections, tolerance to the suppression of intake developed in the bottle-fed group, accompanied by decreased activity. After the tolerance phase, switching from bottle to cannula feeding produced further increases in intake, whereas switching from cannula to bottle feeding produced decreased intakes. These results suggest that (a) cathinone suppresses intake by inducing locomotion and stereotypy, which interfere with the appetitive phase of feeding, and (b) tolerance to drug-induced hypophagia involves learning to suppress such movements, as proposed by the instrumental learning model.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Wolgin DL,Munoz JRdoi
10.1037/0735-7044.120.2.362subject
Has Abstractpub_date
2006-04-01 00:00:00pages
362-70issue
2eissn
0735-7044issn
1939-0084pii
2006-05348-014journal_volume
120pub_type
杂志文章abstract::Involvement of hippocampus in short-delay eye blink conditioning was reexamined during conditioned response (CR) consolidation. Rabbits received bilateral hippocampectomy, removal of overlying neocortex, or sham lesions and were trained with tone/puff pairings to early acquisition (consolidation) or well trained (over...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.5.935
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
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doi:
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
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