The midbrain periaqueductal gray and fear extinction: opioid receptor subtype and roles of cyclic AMP, protein kinase A, and mitogen-activated protein kinase.

abstract：:Although mnemonic interpretations of hippocampal function in people have been readily accepted for many years, similar interpretations of hippocampal function in animals have received a number of challenges. This article reviews two of these challenges, shows how they were resolved in favor of some kind of mnemonic in...

journal_title：Behavioral neuroscience

authors： Olton DS,Wible CG,Shapiro ML

更新日期：1986-12-01 00:00:00

abstract：:The role of the hippocampus in associative learning was investigated in 3 experiments with rats as subjects. Hippocampal rats were impaired in the acquisition of conditioned responding both when food was signaled by the insertion of a lever (Experiment 1) and when the presentation of auditory or visual events served a...

journal_title：Behavioral neuroscience

authors： Good M,Honey RC

更新日期：1991-08-01 00:00:00

abstract：:Activation of memory retrieval after weak learning (WL), during either the short- or intermediate-term stages of memory in day-old chickens, resulted in the strengthening of the memory to levels normally associated with strong learning. Administration of the calcium channel antagonist lanthanum chloride, the glutamate...

journal_title：Behavioral neuroscience

authors： Summers MJ,Crowe SF,Ng KT

更新日期：2000-08-01 00:00:00

abstract：:A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...

journal_title：Behavioral neuroscience

authors： Hotsenpiller G,Horak BT,Wolf ME

更新日期：2002-08-01 00:00:00

abstract：:The acquisition and performance of a self-paced test of spatial divided attention linked with frontal cortex function were assessed in postpubertal (> 60 days) normal or gonadectomized male and female rats. Males were more accurate at detecting relatively brief visual stimuli than females, but this difference was elim...

journal_title：Behavioral neuroscience

authors： Jentsch JD,Taylor JR

更新日期：2003-02-01 00:00:00

abstract：:The hippocampal formation (comprising the hippocampus proper, the dentate gyrus, and the subiculum) has been repeatedly implicated in information storage models of the mammalian brain. The precise nature of the hippocampal role in the storage of information has, however, remained elusive. Here it is proposed that the ...

journal_title：Behavioral neuroscience

authors： Teyler TJ,DiScenna P

更新日期：1986-04-01 00:00:00

abstract：:The authors demonstrated the efficacy of enriched housing conditions in promoting the behavioral recovery and neuronal survival following subicular lesion in rats. Chemical lesioning of the ventral subiculum impaired the spatial learning performances in rats. The lesion also induced a significant degree of neurodegene...

journal_title：Behavioral neuroscience

authors： Dhanushkodi A,Bindu B,Raju TR,Kutty BM

更新日期：2007-06-01 00:00:00

abstract：:The nature of anticipatory responding in rats with unilateral subthalamic nucleus lesions was examined. Rats were trained to respond toward visual targets that were preceded by 1 of 4 different cues. For normal rats, a cue invokes an involuntary attentional orienting that enhances processing of the target at the locat...

journal_title：Behavioral neuroscience

authors： Phillips JM,Brown VJ

更新日期：2000-02-01 00:00:00

abstract：:Supplemental choline during early stages of development can result in long-lasting improvements to memory function. In addition, pre- or postnatal choline has been shown to be protective against some of the adverse effects of early alcohol exposure. The present experiment examined whether supplemental choline given to...

journal_title：Behavioral neuroscience

authors： Hunt PS

更新日期：2012-08-01 00:00:00

abstract：:Animals with sham operations, hippocampal formation, or small and large parietal cortex lesions were trained in a task that required memory for short or long lists of items (spatial locations). More specifically, on any one trial, a rat is presented with 2, 4, 6, 8, or 10 items (spatial locations) on a 12-arm radial m...

journal_title：Behavioral neuroscience

authors： Kametani H,Kesner RP

更新日期：1989-02-01 00:00:00

abstract：:The possibility that female-paced coital behavior induces a reward state of sufficient intensity and duration to induce conditioning was evaluated by the conditioned-place-preference paradigm. Ovariectomized female rats, treated with estradiol benzoate and progesterone, regulated (paced) their coital interactions with...

journal_title：Behavioral neuroscience

authors： Paredes RG,Alonso A

更新日期：1997-02-01 00:00:00

abstract：:The hippocampus has been implicated in anxiety, novelty detection, spatial- contextual processing, and hyperactivity. Accordingly, the authors contrasted the role of the dorsal hippocampus (DH) and the basolateral amygdala complex (BLA) in an open field task that presents the onset and termination of a bright light gr...

journal_title：Behavioral neuroscience

authors： Godsil BP,Stefanacci L,Fanselow MS

更新日期：2005-10-01 00:00:00

abstract：:The present study was designed to evaluate the impact of neonatal injury on adult spinal plasticity in rats. Subjects were randomly assigned to 1 of 4 experimental conditions: (a) hind-paw injury at Postnatal Day (PD) 2, (b) hind-paw injury at PD 5, (c) anesthesia exposure only on PD 2, or (d) anesthesia exposure only...

journal_title：Behavioral neuroscience

authors： Young EE,Baumbauer KM,Elliot A,Joynes RL

更新日期：2007-10-01 00:00:00

abstract：:The ability of men to identify popular word associations had earlier been shown to be affected by left-sided thalamic surgery for movement disorders; now, over a year later, the impairment has been observed with operations on both sides. In addition, upon testing at approximately the same time interval, men who had un...

journal_title：Behavioral neuroscience

authors： Lansdell H

更新日期：1989-08-01 00:00:00

abstract：:Technological advances over the last decade are changing the face of behavioral neuroscience research. Here we review recent work on the use of one such transformative tool in behavioral neuroscience research, chemogenetics (or Designer Receptors Exclusively Activated by Designer Drugs, DREADDS). As transformative tec...

journal_title：Behavioral neuroscience

authors： Smith KS,Bucci DJ,Luikart BW,Mahler SV

更新日期：2016-04-01 00:00:00

abstract：:Previous findings are discordant regarding the effects of perinatal lesions of Cortical Areas 17 and 18 on visual discrimination learning in cats. Three potential determinants of such sparing were investigated: age at lesion (4 or 181 days), age at testing (3 or 9 months), and stimulus complexity. Age at testing was n...

journal_title：Behavioral neuroscience

authors： Cornwell P,Herbein S,Corso C,Eskew R,Warren JM,Payne B

更新日期：1989-12-01 00:00:00

abstract：:Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway...

journal_title：Behavioral neuroscience

authors： Reeves TM,Smith DC

更新日期：1987-04-01 00:00:00

abstract：:Covert shifts of visual attention in space have been quantified by measuring the effects of visual cues on the detection of visual targets in humans and monkeys maintaining visual fixation. These observations of "covert orienting" have provided important information regarding the neurobiology of visual attention in pr...

journal_title：Behavioral neuroscience

authors： Bushnell PJ

更新日期：1995-12-01 00:00:00

abstract：:Recent work from our laboratory demonstrates that both young and adult rats show a preference for directional responding over place navigation in the Morris water task. Based on these findings, previous studies on the postnatal development of spatial learning have most likely assessed the ontogeny of directional respo...

journal_title：Behavioral neuroscience

authors： Akers KG,Candelaria-Cook FT,Rice JP,Johnson TE,Hamilton DA

更新日期：2009-04-01 00:00:00

abstract：:A differentiation was made between dispositional memory and representational memory. A delayed-nonmatching-to-sample task in a T-maze operationalized this distinction. Experimental brain lesions in posterior septum and in prelimbic cortex resulted in amnesia for representational memories. The amnesia ameliorated as a ...

journal_title：Behavioral neuroscience

authors： Thomas GJ,Spafford PS

更新日期：1984-06-01 00:00:00

abstract：:Amnesic patients (n = 8), who have severely impaired declarative memory, learned a probabilistic classification task at the same rate as normal subjects (n = 16) but subsequently were impaired on transfer tests that required flexible use of their task knowledge. A second group of controls (n = 20) rated the questions ...

journal_title：Behavioral neuroscience

authors： Reber PJ,Knowlton BJ,Squire LR

更新日期：1996-10-01 00:00:00

abstract：:Auditory streaming describes a percept in which a sequential series of sounds either is segregated into different streams or is integrated into one stream based on differences in their spectral or temporal characteristics. This phenomenon has been analyzed in human subjects (psychophysics) and European starlings (neur...

journal_title：Behavioral neuroscience

authors： Dolležal LV,Itatani N,Günther S,Klump GM

更新日期：2012-12-01 00:00:00

abstract：:Two experiments explored the role of the opioid system in a situation involving a surprising reduction in reward magnitude: consummatory successive negative contrast. Rats received access to 32% sucrose solution (preshift Trials 1-10) followed by 4% solution (postshift Trials 11-15). Independent groups received an inj...

journal_title：Behavioral neuroscience

authors： Wood M,Daniel AM,Papini MR

更新日期：2005-04-01 00:00:00

abstract：:This series of experiments investigated the role of a prefrontal cortical-dorsal striatal circuit in attention, using a continuous performance task of sustained and spatially divided visual attention. A unilateral excitotoxic lesion of the medial prefrontal cortex and a contralateral lesion of the medial caudate-putam...

journal_title：Behavioral neuroscience

authors： Christakou A,Robbins TW,Everitt BJ

更新日期：2001-08-01 00:00:00

abstract：:The behavior of fetal rats was examined on Day 19 of gestation with procedures that enabled chemical stimulation and direct observation of fetuses. Rat fetuses are sensitive to both tactile stroking and intraoral infusion of chemical solutions, but the pattern and amount of activity depend upon the modality of stimula...

journal_title：Behavioral neuroscience

authors： Smotherman WP,Robinson SR

更新日期：1988-02-01 00:00:00

abstract：:In order to measure tinnitus induced by sodium salicylate injections, 84 pigmented rats, distributed among 14 groups in five experiments, were used in a conditioned suppression paradigm. In Experiment 1, all groups were trained with a conditioned stimulus (CS) consisting of the offset of a continuous background noise....

journal_title：Behavioral neuroscience

authors： Jastreboff PJ,Brennan JF,Coleman JK,Sasaki CT

更新日期：1988-12-01 00:00:00

abstract：:In the cognitive mapping theory of hippocampal function, currently active place cells represent a rat's spatial location (J. O'Keefe & L. Nadel, 1978). A systematic shift of firing field locations should therefore produce a similar shift in a rat's judgment of its location. A. A. Fenton, G. Csizmadia, and R. U. Muller...

journal_title：Behavioral neuroscience

authors： Kubie JL,Fenton A,Novikov N,Touretzky D,Muller RU

更新日期：2007-08-01 00:00:00

abstract：:Previous research conducted in monkeys and rats has established that the perirhinal cortex is critically involved in object- or stimulus-recognition memory, whereas other research suggests this region may contribute to memory for object discriminations. These findings do not rule out the possibility that the perirhina...

journal_title：Behavioral neuroscience

authors： Wiig KA,Burwell RD

更新日期：1998-08-01 00:00:00

abstract：:To determine whether dopamine signaling in the dorsal striatum is sufficient for performance of goal-directed behaviors, local dopamine production was restored in the dorsal striatum of dopamine-deficient (DD) mice through viral-mediated gene therapy. Virally rescued DD (vrDD) mice were tested for learning of an appet...

journal_title：Behavioral neuroscience

authors： Robinson S,Sotak BN,During MJ,Palmiter RD

更新日期：2006-02-01 00:00:00

abstract：:The role of cholecystokinin (CCK) in food intake was investigated in rats by using BIM-18216, a novel CCK receptor antagonist. In rats fed 6 hr/day, BIM-18216 antagonized the reduction of food intake induced by exogenous CCK octapeptide (CCK-8; 4 micrograms/kg) in a dose-dependent manner and had a maximum effect at 1 ...

journal_title：Behavioral neuroscience

authors： Laferrere B,Nguyen M,Bonhomme G,Legall A,Basdevant A,Guy-Grand B

更新日期：1991-10-01 00:00:00