Local dopamine production in the dorsal striatum restores goal-directed behavior in dopamine-deficient mice.

abstract：:To assess the relative permanence of dendritic alterations induced by postweaning housing conditions, dendritic field parameters in the occipital cortex were compared among rats that had spent 30 days, beginning at 23-25 days of age, in a "superenriched" environment, rats that had the same treatment followed by 30 day...

journal_title：Behavioral neuroscience

authors： Camel JE,Withers GS,Greenough WT

更新日期：1986-12-01 00:00:00

abstract：:The amygdala is an integrator of affective processing, and a key component of a network regulating social behavior. While decades of lesion studies in nonhuman primates have shown alterations in social interactions after amygdala damage, acute manipulations of the amygdala in primates have been underexplored. We recen...

journal_title：Behavioral neuroscience

authors： Forcelli PA,Wellman LL,Malkova L

更新日期：2017-04-01 00:00:00

abstract：:The role of thyroid hormones in vertebrate development has been well documented for several decades. As hypothyroidism during critical periods of development can cause defects to the development of every major organ system, including brain, eye, and general morphology, we hypothesized that hypothyroidism would affect ...

journal_title：Behavioral neuroscience

authors： Reider M,Connaughton VP

更新日期：2015-10-01 00:00:00

abstract：:Parametric manipulations of the task demand were used to examine the role of the hippocampus and amygdala in nonspatial and spatial working memory in rats. Hippocampal lesions produced an immediate and long-lasting impairment of nonspatial working memory in an operant task. The memory deficits increased as the delay i...

journal_title：Behavioral neuroscience

authors： Wan RQ,Pang K,Olton DS

更新日期：1994-10-01 00:00:00

abstract：:Rats with perirhinal cortex lesions were sequentially trained in a rectangular water tank on a series of 3 visual discriminations, each between mirror-imaged stimuli. When these same discriminations were tested concurrently, the rats were forced to use a configural strategy to solve the problems effectively. There was...

journal_title：Behavioral neuroscience

authors： Aggleton JP,Albasser MM,Aggleton DJ,Poirier GL,Pearce JM

更新日期：2010-02-01 00:00:00

abstract：:The hippocampus has been implicated in anxiety, novelty detection, spatial- contextual processing, and hyperactivity. Accordingly, the authors contrasted the role of the dorsal hippocampus (DH) and the basolateral amygdala complex (BLA) in an open field task that presents the onset and termination of a bright light gr...

journal_title：Behavioral neuroscience

authors： Godsil BP,Stefanacci L,Fanselow MS

更新日期：2005-10-01 00:00:00

abstract：:Neuromuscular impairment by ethanol likely involves complex effects on balance, gait, muscle strength, and other features of motor coordination. The present experiments showed that relative sensitivity to ethanol-induced motor impairment in serotonin 1B (5-HT(1B)) null mutant and control mice was task dependent. We fo...

journal_title：Behavioral neuroscience

authors： Boehm SL 2nd,Schafer GL,Phillips TJ,Browman KE,Crabbe JC

更新日期：2000-04-01 00:00:00

abstract：:The influence of 4-hydroxyamphetamine (4-OHAM) on food and water intake and in vivo brown adipose thermogenesis was examined in two experiments. In Experiment 1, female rats were treated with 0.00, 0.25, 0.50, 1.00, or 2.00 mg/kg 4-OHAM (ip) prior to assessment of interscapular brown adipose tissue (IBAT) thermogenesi...

journal_title：Behavioral neuroscience

authors： Wellman PJ,Watkins-Freeman PA

更新日期：1984-12-01 00:00:00

abstract：:Fear conditioning shows associations formed between contextual or auditory stimuli with an unconditioned stimulus. Inbred mouse strains differ in their ability to demonstrate fear conditioning, suggesting at least a partial genetic influence. The present study identified the possible chromosomal loci regulating fear c...

journal_title：Behavioral neuroscience

authors： Owen EH,Christensen SC,Paylor R,Wehner JM

更新日期：1997-04-01 00:00:00

abstract：:The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...

journal_title：Behavioral neuroscience

authors： Epstein LH,Temple JL,Neaderhiser BJ,Salis RJ,Erbe RW,Leddy JJ

更新日期：2007-10-01 00:00:00

abstract：:Single unit activity was recorded from the rat hippocampal CA1 and CA3 subfields, dentate gyrus (DG), entorhinal cortex (EC), subicular complex (SB), motor cortex (MC), prefrontal cortex (PFC), and dorsomedial thalamus (DMT) during performance of a continuous non-matching-to-sample task. The rats made go and no-go res...

journal_title：Behavioral neuroscience

authors： Sakurai Y

更新日期：1990-04-01 00:00:00

abstract：:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexp...

journal_title：Behavioral neuroscience

authors： Holland PC,Gallagher M

更新日期：1993-04-01 00:00:00

abstract：:The rewarding properties of centrally administered ethanol (EtOH) were examined using a conditioned place preference (CPP) test. Male rats subjected to bilateral intracerebroventricular (icv) infusions of EtOH (0-240 nmol) produced a dose-dependent preference for the drug-paired environment that was potentiated by con...

journal_title：Behavioral neuroscience

authors： Walker BM,Ettenberg A

更新日期：2007-04-01 00:00:00

abstract：:The addition of extra light-alone or rotation-alone presentations to sequences of light-rotation pairings reduced the associative suppression of phototaxic behavior for the nudibranch Hermissenda. Training-induced changes in Type B photoreceptor light responses were found to parallel the training-induced behavioral ch...

journal_title：Behavioral neuroscience

authors： Farley J

更新日期：1987-02-01 00:00:00

abstract：:Morphological changes in the anterior cingulate cortex are found in subjects with schizophrenia, attention deficit hyperactivity disorder, and obsessive-compulsive disorder. These changes are hypothesized to underlie the impairments these individuals show on tasks that require cognitive control. The anterior cingulate...

journal_title：Behavioral neuroscience

authors： Newman LA,McGaughy J

更新日期：2011-06-01 00:00:00

abstract：:The behavior of fetal rats was examined on Day 19 of gestation with procedures that enabled chemical stimulation and direct observation of fetuses. Rat fetuses are sensitive to both tactile stroking and intraoral infusion of chemical solutions, but the pattern and amount of activity depend upon the modality of stimula...

journal_title：Behavioral neuroscience

authors： Smotherman WP,Robinson SR

更新日期：1988-02-01 00:00:00

abstract：:While under deep barbiturate anesthesia, rats received a series of 10 classical conditioning trials in which white noise was paired with intramuscular shock. The anesthetized animals received either saline or epinephrine injections prior to the training trials. Independent sets of animals were tested for retention per...

journal_title：Behavioral neuroscience

authors： Gold PE,Weinberger NM,Sternberg DB

更新日期：1985-10-01 00:00:00

abstract：:Similar to elderly humans, aged Long-Evans rats exhibit individual differences in performance on tasks that critically depend on the medial temporal lobe memory system. Although reduced memory performance is common, close to half of aged rats in this outbred rodent population perform within the range of young subjects...

journal_title：Behavioral neuroscience

authors： Haberman RP,Monasterio A,Branch A,Gallagher M

更新日期：2019-10-01 00:00:00

abstract：:In humans, congenital deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a disorder known as the Lesch-Nyhan syndrome. Patients with this disorder exhibit a prominent neurobehavioral phenotype that results in part from dysfunction of catecholaminergic systems in the striatum. HPR...

journal_title：Behavioral neuroscience

authors： Jinnah HA,Gage FH,Friedmann T

更新日期：1991-12-01 00:00:00

abstract：:An influential view in the field of spatial cognition is that an obligatory geometric module constrains spatial learning and memory. In this issue, P. M. Jones, J. M. Pearce, V. J. Davies, M. A. Good, and A. McGregor (2007) showed that learning based on the geometry, or shape, of the environment requires the hippocamp...

journal_title：Behavioral neuroscience

authors： Dudchenko PA

更新日期：2007-12-01 00:00:00

abstract：:The acoustic startle reflex (ASR) is potentiated during negative emotion, but attenuated during positive emotional experience. The modulation of the ASR by fear depends critically on the amygdala. The authors investigated ASR modulation to fearful, disgusting, pleasant, and neutral stimuli in 12 patients with unilater...

journal_title：Behavioral neuroscience

authors： Buchanan TW,Tranel D,Adolphs R

更新日期：2004-04-01 00:00:00

abstract：:The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...

journal_title：Behavioral neuroscience

authors： Jasnow AM,Shi C,Israel JE,Davis M,Huhman KL

更新日期：2005-08-01 00:00:00

abstract：:One-month-old rats were fed 1 of 4 high-fat diets (20% fat) or chow (4.5% fat) for 3 months. Dietary saturated (SFA), monounsaturated (MUFA), or polyunsaturated (PUFA) fatty acids varied such that their independent effects on cognitive performance could be tested. Rats were tested on a variable-interval delayed-altern...

journal_title：Behavioral neuroscience

authors： Greenwood CE,Winocur G

更新日期：1996-06-01 00:00:00

abstract：:Experimental data and computational models suggest that blockade of muscarinic cholinergic receptors impairs paired-associate learning and increases proactive interference (E. DeRosa & M. E. Hasselmo, 2000; M. E. Hasselmo & J. M. Bower, 1993). The results presented here provide evidence in humans supporting these hypo...

journal_title：Behavioral neuroscience

authors： Atri A,Sherman S,Norman KA,Kirchhoff BA,Nicolas MM,Greicius MD,Cramer SC,Breiter HC,Hasselmo ME,Stern CE

更新日期：2004-02-01 00:00:00

abstract：:Classical conditioning of the rabbit eyeblink response was used to study the effects of cerebellar lesions on performance in animals trained with low-intensity unconditioned stimuli (US). Animals were trained with 1 of 2 low-intensity corneal-airpuff USs paired with a tone-conditioned stimulus. This study confirms ear...

journal_title：Behavioral neuroscience

authors： Ivkovich D,Lockard JM,Thompson RF

更新日期：1993-06-01 00:00:00

abstract：:The authors report an effort to advance animal models that mimic the cognitive decline of Alzheimer's disease. Rats were trained and repeatedly tested in a spatial delayed matching-to-position paradigm in the water maze, with the location of the submerged platform changing between, but not within, days. After Trial 1 ...

journal_title：Behavioral neuroscience

authors： von Linstow Roloff E,Platt B,Riedel G

更新日期：2002-04-01 00:00:00

abstract：:The antinociceptive effects of signaled shock and its physiological underpinnings were examined in two experiments. In Experiment 1, rats were exposed to one of three shock conditions: no shock, unsignaled shock, and signaled (by a 10-s, 1000-Hz tone) shock. In each condition the rats were tested hourly in the absence...

journal_title：Behavioral neuroscience

authors： Guile MN,McCutcheon NB

更新日期：1984-08-01 00:00:00

abstract：:PDAPP transgenic mice have been shown to develop age dependently much of the cerebral histopathology associated with Alzheimer's disease. PDAPP mice (3-10 months old) were tested in a battery of memory tasks to determine whether they develop memory-behavioral deficits and whether these deficits occur before or after a...

journal_title：Behavioral neuroscience

authors： Dodart JC,Meziane H,Mathis C,Bales KR,Paul SM,Ungerer A

更新日期：1999-10-01 00:00:00

abstract：:Reactivation of an already consolidated memory makes it labile for a period of several hrs, which are required for its reconsolidation. Evidence suggests that the return of conditioned fear through spontaneous recovery, reinstatement, or renewal can be prevented by blockading this reconsolidation process using pharmac...

journal_title：Behavioral neuroscience

authors： Meir Drexler S,Merz CJ,Hamacher-Dang TC,Marquardt V,Fritsch N,Otto T,Wolf OT

更新日期：2014-08-01 00:00:00

abstract：:The acoustic startle reflex can be facilitated by the presentation of a train of footshocks presented in rapid succession (footshock sensitization). Acoustic startle is a short-latency reflex mediated by a neural circuit consisting of the ventral cochlear nucleus (VCN), ventral nucleus of the lateral lemniscus (VLL), ...

journal_title：Behavioral neuroscience

authors： Boulis NM,Davis M

更新日期：1989-06-01 00:00:00