Abstract:
:The influence of 4-hydroxyamphetamine (4-OHAM) on food and water intake and in vivo brown adipose thermogenesis was examined in two experiments. In Experiment 1, female rats were treated with 0.00, 0.25, 0.50, 1.00, or 2.00 mg/kg 4-OHAM (ip) prior to assessment of interscapular brown adipose tissue (IBAT) thermogenesis. The 4-OHAM treatment induced dose-dependent activation of IBAT thermogenesis consistent with the enhanced serum levels of norepinephrine and epinephrine observed in 4-OHAM-treated rats immediately after temperature measurement. In Experiment 2, the influence of 4-OHAM on food and water intake was assessed during 120-min test intervals in female rats fed food and water ad lib. Although there was a trend for 4-OHAM to increase water intake, there was no significant effect of 4-OHAM (0.40, 0.80, 1.00, 2.00, and 4.00 mg/kg) on either food or water intake. These data suggest that brown adipose thermogenesis does not play a role in the anorexia induced by amphetamine or in the regulation of feeding.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Wellman PJ,Watkins-Freeman PAdoi
10.1037//0735-7044.98.6.1060subject
Has Abstractpub_date
1984-12-01 00:00:00pages
1060-4issue
6eissn
0735-7044issn
1939-0084journal_volume
98pub_type
杂志文章abstract::The present study was designed to evaluate the impact of neonatal injury on adult spinal plasticity in rats. Subjects were randomly assigned to 1 of 4 experimental conditions: (a) hind-paw injury at Postnatal Day (PD) 2, (b) hind-paw injury at PD 5, (c) anesthesia exposure only on PD 2, or (d) anesthesia exposure only...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.5.1095
更新日期:2007-10-01 00:00:00
abstract::Social signals play a primary role in regulating social relationships among male mice. The present series of experiments investigated the neural mechanisms underlying an induction of amicable cues that facilitate social approach in male mice of the C57BL/6 (B6) and BALB/c (BALB) strains. Male mice exhibit approach beh...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000191
更新日期:2017-04-01 00:00:00
abstract::In sighted humans, light intensity, timing, exposure duration, and spectral composition of light are important to entrain the endogenous circadian pacemaker to the 24-h day-night cycle. We tested the impact of two realistic office lighting conditions during the afternoon on subjective sleepiness, hormonal secretion, a...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0026702
更新日期:2012-02-01 00:00:00
abstract::Male prairie voles (Microtus ochrogaster) form a pair bond with a female partner after mating, and this behavior is regulated by the neuropeptide vasopressin (AVP). The authors report that AVP in the lateral septum is important for pair bond formation. Administration of an AVP V1a receptor antagonist in the lateral se...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.115.4.910
更新日期:2001-08-01 00:00:00
abstract::Two experiments examined the effects of the competitive N-methyl-D-aspartate (NMDA) antagonist D-APV (D-2-amino-5-phosphonovalerate) on rats' ability to acquire potentiated aversions to the odor element of a taste-odor compound. In Experiment 1, pretreatment with D-APV (2.5 micrograms/side icv) caused stereospecific d...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.106.2.315
更新日期:1992-04-01 00:00:00
abstract::Sniffing, a behavior that enhances detection and localization of odorants, is typically assumed to require behavioral arousal. In an effort to determine whether sniffing and arousal are dissociable, dimethyl disulfide (DMDS) was presented to 8-day-old rats while respiration and behavioral state were monitored. Pups sn...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.2.267
更新日期:2004-04-01 00:00:00
abstract::This study examined the effects of intense emotional learning on the sleep-wake state-specific electroencephalographic (EEG) activities of the basolateral (BLA) and central (CeA) nuclei of the amygdala. Rats were trained on a passive-avoidance learning (PAL) protocol that was followed by 6 hr of undisturbed polygraphi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.117.4.751
更新日期:2003-08-01 00:00:00
abstract::Neuropsin (kallikrein-related peptidase 8) is concentrated in the hippocampus, amygdala, olfactory bulb, and prefrontal cortex. Earlier studies showed that protease deficiency causes a significant impairment of early-phase long-term potentiation in the Schaffer collateral pathway and hippocampus-dependent memory in th...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.122.3.498
更新日期:2008-06-01 00:00:00
abstract::Dopamine in the medial preoptic area (MPOA) facilitates copulation in male rats, and nitric oxide (NO) regulates basal and female-stimulated MPOA dopamine release. Microinjection of L-nitro-arginine methyl ester (L-NAME, an NO synthesis inhibitor) into the MPOA blocked copulation in naive rats and impaired copulation ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.6.1317
更新日期:2004-12-01 00:00:00
abstract::Stages of formation of memory and the roles of different forebrain structures in memory formation were investigated by injecting various agents into the brains of chicks close to the time of peck-avoidance training. With L-glutamate injected bilaterally into the hyperstriatum 5 min pretraining, retention was good 1 mi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.100.6.856
更新日期:1986-12-01 00:00:00
abstract::The use of food products designed to mimic the sensory properties of sweet and fat while providing fewer calories has been promoted as a method for reducing food intake and body weight. However, such products may interfere with a learned relationship between the sensory properties of food and the caloric consequences ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0024404
更新日期:2011-08-01 00:00:00
abstract::The effects of exogenous and endogenous steroids on components of female sexual behavior of neonatal male and female rats were investigated. In Experiment 1, 4-day-old rats were treated with 0, 0.1, 1.0, 10, or 100 micrograms/10 g body weight estradiol benzoate (EB) and were tested 44 hr later. In Experiment 2, male r...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.5.718
更新日期:1987-10-01 00:00:00
abstract::The present series of three experiments was concerned with the effects of morphine and the morphine antagonist naloxone on the development of a classical aversive heart rate (HR) conditioned response (CR) to a tone conditioned stimulus (CS) paired with an electric shock unconditioned stimulus (US). In the first study,...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.102.2.244
更新日期:1988-04-01 00:00:00
abstract::A very high correlation was found in rats between latency to escape on the first trial of an active avoidance task and the rate at which [leu]enkephalin is hydrolyzed in plasma. In addition, the rate of [leu]enkephalin hydrolysis is significantly altered following the first training trial. The results suggest that a r...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.102.3.404
更新日期:1988-06-01 00:00:00
abstract::Anterograde amnesia (AA), forgetting of events that occur following a traumatic episode, has recently been demonstrated by using a mild decrease in temperature (hypothermia) as the amnestic agent. However, no data currently exist to indicate if an increase in body temperature (hyperthermia) might affect memory process...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.3.333
更新日期:1987-06-01 00:00:00
abstract::The estradiol (E2), estrogen receptor-α (ERα), testosterone (T), and androgen receptor (AR) can contribute to anxiety, but whether they are associated with the reversion of prenatal adverse outcomes remains unclear. Here, we tested the interactive effects of prenatal maternal restraint stress and early postnatal short...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000094
更新日期:2015-12-01 00:00:00
abstract::Female songbirds use male songs as an important criterion for mate selection. Several studies have reported that female songbirds prefer complex songs to other song types. In a recent study, the authors found that song responsiveness in female zebra finches (Taeniopygia guttata) is strongly modulated by circulating es...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.122.5.1148
更新日期:2008-10-01 00:00:00
abstract::The current study examined possible interactions between genetic factors and prolonged drug access by testing the Fischer (F344), Lewis (LEW), and Wistar rat strains in a prolonged access cocaine self-administration (SA) procedure. Before prolonged access, the strains did not differ in breakpoints for food or cocaine ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0013727
更新日期:2009-02-01 00:00:00
abstract::Adult Japanese quail display left-eye/right-hemisphere dominance in visually guided sexual tracking. In 2 experiments, the authors set out to answer if this functional cerebral asymmetry is modifiable by posthatch monocular deprivation. In Experiment 1, the left or the right eye of 2-day old quail were closed for 70 d...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0016406
更新日期:2009-08-01 00:00:00
abstract::The addition of extra light-alone or rotation-alone presentations to sequences of light-rotation pairings reduced the associative suppression of phototaxic behavior for the nudibranch Hermissenda. Training-induced changes in Type B photoreceptor light responses were found to parallel the training-induced behavioral ch...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.1.13
更新日期:1987-02-01 00:00:00
abstract::An acoustic stimulus previously paired with footshock elicits stereotyped increases in arterial pressure and heart rate and induces freezing behavior in freely behaving rats. Although the arterial pressure and freezing responses differ between groups given paired and random presentations of the tone and shock, the inc...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.102.1.66
更新日期:1988-02-01 00:00:00
abstract::Previous work has demonstrated an important role for adrenergic receptors in memory processes in fear and drug conditioning paradigms. Recent studies have also demonstrated alterations in extinction in these paradigms using drug treatments targeting beta- and alpha2-adrenergic receptors, but little is known about the ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0018909
更新日期:2010-04-01 00:00:00
abstract::Cost-benefit decision making is essential for organisms to adapt to their ever-changing environment. Most studies of cost-benefit decision making involve choice conditions in which effort and value are varied simultaneously. This prevents identification of the aspects of cost-benefit decision making that are affected ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000361
更新日期:2020-04-01 00:00:00
abstract::This study assessed the activity of head direction (HD) cells during performance of a spatial reference memory task on a radial arm maze. Rats were trained to select a maze arm located in a constant position in relation to a salient extramaze visual landmark. HD cell discharge properties remained relatively stable acr...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.1.3
更新日期:1997-02-01 00:00:00
abstract::Four experiments studied the opioid receptor subtype and signal transduction mechanisms mediating fear extinction in the ventrolateral quadrant of the midbrain periaqueductal gray (vlPAG). Microinjection of a mu- but not a delta- or kappa-opioid receptor antagonist into the vlPAG retarded extinction. Extinction was al...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.119.4.1023
更新日期:2005-08-01 00:00:00
abstract::Although mnemonic interpretations of hippocampal function in people have been readily accepted for many years, similar interpretations of hippocampal function in animals have received a number of challenges. This article reviews two of these challenges, shows how they were resolved in favor of some kind of mnemonic in...
journal_title:Behavioral neuroscience
pub_type: 杂志文章,评审
doi:10.1037//0735-7044.100.6.852
更新日期:1986-12-01 00:00:00
abstract::Previous electrophysiological studies and computational modeling suggest the hypothesis that cholinergic neuromodulation may reduce olfactory associative interference during learning (M. E. Hasselmo, B. P. Anderson, & J. M. Bower, 1992; M. E. Hasselmo & J. M. Bower, 1993). These results provide behavioral evidence sup...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract::The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent m...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.117.1.184
更新日期:2003-02-01 00:00:00
abstract::This experiment investigated the development of caching behavior and the hippocampus (HF) in postfledging mountain chickadees (Poecile gambeli). From Days 35 to 53, the number of seeds stored increased but the proportion recovered did not. Birds that stored and recovered during 3 or more trials had significantly enlar...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.115.3.614
更新日期:2001-06-01 00:00:00
abstract::Recent studies of delay eyeblink conditioning (EBC) in young rats have demonstrated different effects of various conditioned and unconditioned stimulus (CS-US) preexposure conditions on learning at different ages. The present study extends this research to trace EBC. Subjects experienced 1 of 3 preexposure conditions ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.120.2.257
更新日期:2006-04-01 00:00:00