Abstract:
:Anterograde amnesia (AA), forgetting of events that occur following a traumatic episode, has recently been demonstrated by using a mild decrease in temperature (hypothermia) as the amnestic agent. However, no data currently exist to indicate if an increase in body temperature (hyperthermia) might affect memory processing in a similar manner. Experiments 1 and 2 demonstrated that increasing the colonic body temperature of the rat to 3-4 degrees C or more above normal during avoidance training produced a significant retention loss when the test occurred 24 hr after training. Slight hyperthermia to 1-2 degrees C above normal did not impair retention. In Experiment 3, AA resulting from an elevation in temperature was reversed by reheating "amnestic" subjects just prior to the 24-hr test. By rapidly reversing hyperthermia immediately after the training trial with a cooling procedure, Experiment 4 demonstrated that hyperthermia-induced AA was not the result of retrograde influences of the heating treatment. Implications of these results are discussed in terms of possible retention deficits which could conceivably follow environmental heat stress or fever hyperthermia resulting from bacterial infection.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Ahlers ST,Riccio DCdoi
10.1037//0735-7044.101.3.333subject
Has Abstractpub_date
1987-06-01 00:00:00pages
333-40issue
3eissn
0735-7044issn
1939-0084journal_volume
101pub_type
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2001-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2004-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2016-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.3.586
更新日期:2007-06-01 00:00:00
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更新日期:2005-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2006-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2008-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1985-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2001-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 临床试验,杂志文章
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更新日期:2003-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1999-06-01 00:00:00
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pub_type: 杂志文章
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