Pedunculopontine tegmental nucleus lesions impair stimulus--reward learning in autoshaping and conditioned reinforcement paradigms.

abstract：:In four experiments we reexamined the recent report by Labbe, Firl, Mufson, and Stein (1983) that fetal cortical tissue transplanted to an aspirative prefrontal cortical cavity in rats can ameliorate the learning impairments induced by the aspirative lesions. Healthy surviving grafts from young (E16) embryonic donors ...

journal_title：Behavioral neuroscience

authors： Dunnett SB,Ryan CN,Levin PD,Reynolds M,Bunch ST

更新日期：1987-08-01 00:00:00

abstract：:Available evidence indicates that common genes influence alcohol and tobacco abuse in humans. The studies reported here used mouse models to evaluate the hypothesis that genetically determined variability in the alpha4beta2* nicotinic receptor modulates genetically determined variability in the intake of both nicotine...

journal_title：Behavioral neuroscience

authors： Butt CM,King NM,Hutton SR,Collins AC,Stitzel JA

更新日期：2005-02-01 00:00:00

abstract：:Methylphenidate (MPD) is widely prescribed for attention-deficit/hyperactivity disorder in the United States. Patients, mostly school-age children, are taking the drug orally. To simulate the human condition, the authors used a cracker to administer methylphenidate orally (without the stress of handling) from Postnata...

journal_title：Behavioral neuroscience

authors： Zhu N,Weedon J,Dow-Edwards DL

更新日期：2007-12-01 00:00:00

abstract：:While under deep barbiturate anesthesia, rats received a series of 10 classical conditioning trials in which white noise was paired with intramuscular shock. The anesthetized animals received either saline or epinephrine injections prior to the training trials. Independent sets of animals were tested for retention per...

journal_title：Behavioral neuroscience

authors： Gold PE,Weinberger NM,Sternberg DB

更新日期：1985-10-01 00:00:00

abstract：:The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...

journal_title：Behavioral neuroscience

authors： Jasnow AM,Shi C,Israel JE,Davis M,Huhman KL

更新日期：2005-08-01 00:00:00

abstract：:The effects of dl-cathinone on milk intake and motor activity were investigated in bottle- and cannula-fed rats. Acute injections of cathinone produced dose-dependent increases in activity in both groups but only produced decreased intake in bottle-fed rats. With chronic injections, tolerance to the suppression of int...

journal_title：Behavioral neuroscience

authors： Wolgin DL,Munoz JR

更新日期：2006-04-01 00:00:00

abstract：:The shy-bold continuum is a fundamental behavioral trait conserved across human and nonhuman animals. Individual differences along the shy-bold continuum are presumed to arise from, and are maintained by, differences in the excitability of forebrain limbic areas involved in the evaluation of stimulus saliency. To test...

journal_title：Behavioral neuroscience

authors： Beaton EA,Schmidt LA,Schulkin J,Antony MM,Swinson RP,Hall GB

更新日期：2008-06-01 00:00:00

abstract：:Previous work has demonstrated an important role for adrenergic receptors in memory processes in fear and drug conditioning paradigms. Recent studies have also demonstrated alterations in extinction in these paradigms using drug treatments targeting beta- and alpha2-adrenergic receptors, but little is known about the ...

journal_title：Behavioral neuroscience

authors： Bernardi RE,Lattal KM

更新日期：2010-04-01 00:00:00

abstract：:Although decorticated rats are able to engage in play, their play is abnormal in three ways. First, decorticates do not display the normal, age-related shifts in defensive strategies during development. Second, decorticates do not modify their defensive tactics in response to the social identity of their partners. Thi...

journal_title：Behavioral neuroscience

authors： Bell HC,McCaffrey DR,Forgie ML,Kolb B,Pellis SM

更新日期：2009-12-01 00:00:00

abstract：:Repeated exposure to female-related stimuli causes functional alterations in the neural circuitry mediating male rat sexual behavior. In a study published in the current issue of this journal, G. M. Lagoda, J. W. Muschamp, A. Vigdorchik, and E. M. Hull (2004) provide interesting new evidence as to the mechanisms respo...

journal_title：Behavioral neuroscience

authors： Coolen LM

更新日期：2004-12-01 00:00:00

abstract：:Female ovariectomized (OVX) and sham-OVX rats were trained in a task designed to assess sustained attention. After achieving asymptotic performance, OVX rats did not exhibit the impairment in performance over blocks of trials (i.e., the vigilance decrement) observed in sham-OVX rats. Furthermore, OVX rats' performance...

journal_title：Behavioral neuroscience

authors： McGaughy J,Sarter M

更新日期：1999-12-01 00:00:00

abstract：:Rats implanted with cannula tips placed above the nucleus of the solitary tract (NTS) were trained to obtain food pellets placed in 2 arms of a Y maze and then given a footshock in 1 arm of the maze. The rats then received bilateral injections of lidocaine or buffer into the NTS and peripheral injections of saline or ...

journal_title：Behavioral neuroscience

authors： Williams CL,McGaugh JL

更新日期：1993-12-01 00:00:00

abstract：:Rabbits received ibotenic acid lesions of the mediodorsal nucleus of the thalamus (MD) or sham lesions. These animals were compared on 4 sessions of Pavlovian eyeblink and heart rate conditioning, in which a tone was the conditioned stimulus and a paraorbital electrical shock was the unconditioned stimulus. Lesions of...

journal_title：Behavioral neuroscience

authors： Buchanan SL,Thompson RH

更新日期：1990-12-01 00:00:00

abstract：:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexp...

journal_title：Behavioral neuroscience

authors： Holland PC,Gallagher M

更新日期：1993-04-01 00:00:00

abstract：:Based on work done in animal models showing that autism-like symptoms are ameliorated following exposure to an enriched sensorimotor environment, we attempted to develop a comparable therapy for children with autism. In an initial randomized controlled trial, children with autism who received sensorimotor enrichment a...

journal_title：Behavioral neuroscience

authors： Woo CC,Donnelly JH,Steinberg-Epstein R,Leon M

更新日期：2015-08-01 00:00:00

abstract：:The rat's willingness to ingest glucose after an initial intraoral intake test was probed by beginning a 2nd intraoral intake test at variable durations (1-120 min). In Experiment 1, after an initial meal of 12.5% glucose solution averaging 26.9 +/- 1.7 ml (SEM, n = 10), the size of the 2nd (probe) meal of the same st...

journal_title：Behavioral neuroscience

authors： Kaplan JM,Seeley RJ,Grill HJ

更新日期：1994-04-01 00:00:00

abstract：:Young and aged animals were tested on a spatial alternation task that consisted of two interleaved components: (1) an "outbound" or alternation component (working memory) and (2) an "inbound" component, requiring the animal to remember to return to a central location in space (spatial memory). In the present study, ag...

journal_title：Behavioral neuroscience

authors： Kapellusch AJ,Lester AW,Schwartz BA,Smith AC,Barnes CA

更新日期：2018-12-01 00:00:00

abstract：:Lurcher mutant (+/Lc) mice exhibit a massive loss of neurons in the cerebellar cortex and in the inferior olivary nucleus while deep cerebellar nuclei are essentially intact. To discriminate the respective participation of the cerebellar cortex and deep structures in learning and memory, the authors subjected 3- to 6-...

journal_title：Behavioral neuroscience

authors： Caston J,Vasseur F,Delhaye-Bouchaud N,Mariani J

更新日期：1997-02-01 00:00:00

abstract：:Mice unable to synthesize dopamine (DA) in dopaminergic neurons were generated by gene-targeting techniques (Q.-Y. Zhou & R. D. Palmiter, 1995). These dopamine-deficient (DA-/-) mice required daily administration of 3,4-dihydroxyphenylalanine (L-DOPA) for survival beyond 2 to 3 weeks of age. This treatment stimulated ...

journal_title：Behavioral neuroscience

authors： Szczypka MS,Zhou QY,Palmiter RD

更新日期：1998-10-01 00:00:00

abstract：:The purpose of this study was to evaluate the sensorimotor skills of a spontaneous mouse mutant, Purkinje cell degeneration (PCD), marked by selective cerebellar cortical atrophy on a treadmill activated at 1 of 2 speeds and at 1 of 3 slopes, requiring forward movements to avoid footshocks. There was no difference in ...

journal_title：Behavioral neuroscience

authors： Le Marec N,Lalonde R

更新日期：1998-02-01 00:00:00

abstract：:Trace eyeblink classical conditioning was assessed in patients with bilateral medial-temporal amnesia and matched control participants who had previously shown equivalent delay eyeblink conditioning (J. D. E. Gabrieli et al., 1995). The silent trace interval varied for durations of 500, 750, or 1,000 ms in successive ...

journal_title：Behavioral neuroscience

authors： McGlinchey-Berroth R,Carrillo MC,Gabrieli JD,Brawn CM,Disterhoft JF

更新日期：1997-10-01 00:00:00

abstract：:To test whether habituation is specific to the stimulus modality, the authors analyzed cross-habituation between the tactile startle response' (TSR) and the acoustic startle response (ASR). The acoustic artifacts of airpuffs used to elicit the TSR were reduced by using a silencer and were effectively masked by backgro...

journal_title：Behavioral neuroscience

authors： Pilz PK,Carl TD,Plappert CF

更新日期：2004-10-01 00:00:00

abstract：:The context preexposure facilitation effect (CPFE) is a variant of contextual fear conditioning in which context learning, context-shock association, and expression of context conditioning occur in 3 separate phases-preexposure, training, and testing. During the preexposure phase, the CPFE is disrupted by hippocampal ...

journal_title：Behavioral neuroscience

authors： Robinson-Drummer PA,Dokovna LB,Heroux NA,Stanton ME

更新日期：2016-04-01 00:00:00

abstract：:Six females rats were trained to lever press under a free operant shock-postponement schedule. Each subject had a yoked control which received shock whenever the subject did. The shock-postponement interval (R-S) was varied from 5, 10, 20, 40, to 80 s over blocks of sessions. Corticosteroid levels were taken prior to ...

journal_title：Behavioral neuroscience

authors： Herrmann TF,Hurwitz HM,Levine S

更新日期：1984-12-01 00:00:00

abstract：:Biological markers for acquisition and extinction of fear conditioning were studied in 40 individuals selected for displaying either good or poor acquisition of fear conditioning. as estimated by the skin conductance response. Participants with a short serotonin transporter (5-HTT) promoter allele or low monoamine oxi...

journal_title：Behavioral neuroscience

authors： Garpenstrand H,Annas P,Ekblom J,Oreland L,Fredrikson M

更新日期：2001-04-01 00:00:00

abstract：:The present study tested the prediction that D-cycloserine (DCS), a partial N-methyl-D-aspartate agonist, would facilitate extinction of conditioned freezing in male Sprague-Dawley rats. Rats received 5 light-shock pairings (conditioning). The following day, rats received 6 light-alone presentations (extinction traini...

journal_title：Behavioral neuroscience

authors： Ledgerwood L,Richardson R,Cranney J

更新日期：2003-04-01 00:00:00

abstract：:In order to measure tinnitus induced by sodium salicylate injections, 84 pigmented rats, distributed among 14 groups in five experiments, were used in a conditioned suppression paradigm. In Experiment 1, all groups were trained with a conditioned stimulus (CS) consisting of the offset of a continuous background noise....

journal_title：Behavioral neuroscience

authors： Jastreboff PJ,Brennan JF,Coleman JK,Sasaki CT

更新日期：1988-12-01 00:00:00

abstract：:Female rats drink more 3% NaCl solution than do males, both when they need sodium (need-induced sodium intake or sodium appetite) and when they do not (need-free sodium intake). The sexual dimorphism of sodium intake is a secondary sexual characteristic because after castration at 1 day of age male rats drank 3% NaCl ...

journal_title：Behavioral neuroscience

authors： Chow SY,Sakai RR,Witcher JA,Adler NT,Epstein AN

更新日期：1992-02-01 00:00:00

abstract：:These experiments examined the sufficiency of pairing an odor with either intrabulbar activation of noradrenergic beta-receptors or pharmacological stimulation of the locus coeruleus to support learned odor preferences in Postnatal Day 6-7 rat pups. The results showed that pups exposed to odor paired with beta-recepto...

journal_title：Behavioral neuroscience

authors： Sullivan RM,Stackenwalt G,Nasr F,Lemon C,Wilson DA

更新日期：2000-10-01 00:00:00

abstract：:Previous results from our laboratory have demonstrated that 3-day-old rats given dopamine (DA)-depleting brain lesions are spared the severe behavioral dysfunctions seen after comparable brain damage in adults. This behavioral sparing is accompanied by a sprouting of serotonin (5-HT)-containing neurons in the striatum...

journal_title：Behavioral neuroscience

authors： Bruno JP,Jackson D,Zigmond MJ,Stricker EM

更新日期：1987-12-01 00:00:00