Analysis of learning deficits in aged rats on the W-track continuous spatial alternation task.

abstract：:Previous studies in Long-Evans rats demonstrated a significant relationship between variation in pup licking/grooming and arched-back nursing (LG-ABN) and offspring development. However, maternal care is dynamic and exhibits significant temporal variation. In the current study, we assessed temporal variation in LG and...

journal_title：Behavioral neuroscience

authors： Jensen Peña C,Champagne FA

更新日期：2013-02-01 00:00:00

abstract：:The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout traini...

journal_title：Behavioral neuroscience

authors： Nicholson DA,Freeman JH Jr

更新日期：2002-04-01 00:00:00

abstract：:Whether olfactory working memory involves verbal representations or neural images of odor per se remains unclear. This study investigated whether verbal representation influences performance in an olfactory delayed-match-to-sample task and used monorhinal presentation to generate hypotheses as to the underlying anatom...

journal_title：Behavioral neuroscience

authors： Yeshurun Y,Dudai Y,Sobel N

更新日期：2008-10-01 00:00:00

abstract：:The authors demonstrated the efficacy of enriched housing conditions in promoting the behavioral recovery and neuronal survival following subicular lesion in rats. Chemical lesioning of the ventral subiculum impaired the spatial learning performances in rats. The lesion also induced a significant degree of neurodegene...

journal_title：Behavioral neuroscience

authors： Dhanushkodi A,Bindu B,Raju TR,Kutty BM

更新日期：2007-06-01 00:00:00

abstract：:The basal ganglia and the cerebellum are anatomically and functionally linked to the cerebral cortex through a series of well-established circuits. The disruption of dopaminergic projections in Parkinson's disease (PD) leads to an imbalance within these circuits, leading to motor and cognitive symptoms. The cortico-ce...

journal_title：Behavioral neuroscience

authors： Martinu K,Monchi O

更新日期：2013-04-01 00:00:00

abstract：:Social signals play a primary role in regulating social relationships among male mice. The present series of experiments investigated the neural mechanisms underlying an induction of amicable cues that facilitate social approach in male mice of the C57BL/6 (B6) and BALB/c (BALB) strains. Male mice exhibit approach beh...

journal_title：Behavioral neuroscience

authors： Arakawa H

更新日期：2017-04-01 00:00:00

abstract：:Adult rats that were isolated from the mother and nest for 1 hr per day from Postnatal Day 2 to 9 were studied. Controls consisted of handled littermates as well as separate litters that were never handled. As adults, animals were given either a pharmacological challenge (1.0 or 2.0 mg/kg amphetamine) or an environmen...

journal_title：Behavioral neuroscience

authors： Kehoe P,Shoemaker WJ,Triano L,Callahan M,Rappolt G

更新日期：1998-02-01 00:00:00

abstract：:Fluoxetine is the only selective serotonin reuptake inhibitor registered for the treatment of major depressive disorder in pediatric populations, despite reports that it is disproportionately associated with an array of adverse side effects that include agitation, hostility, and overt acts of pathological aggression a...

journal_title：Behavioral neuroscience

authors： Ricci LA,Melloni RH Jr

更新日期：2012-10-01 00:00:00

abstract：:Chorda tympani nerve (CT) transection in rats severely impairs NaCl taste detection. These rats can detect higher concentrations of NaCl, however, suggesting that remaining oral nerves maintain some salt sensibility. Rats were tested in a gustometer with a 2-response operant taste-detection task before and after sham ...

journal_title：Behavioral neuroscience

authors： Blonde GD,Garcea M,Spector AC

更新日期：2006-06-01 00:00:00

abstract：:Six females rats were trained to lever press under a free operant shock-postponement schedule. Each subject had a yoked control which received shock whenever the subject did. The shock-postponement interval (R-S) was varied from 5, 10, 20, 40, to 80 s over blocks of sessions. Corticosteroid levels were taken prior to ...

journal_title：Behavioral neuroscience

authors： Herrmann TF,Hurwitz HM,Levine S

更新日期：1984-12-01 00:00:00

abstract：:Fifty-eight 4-day-old male rats were studied. Peripheral desensitization was induced in 36 rats by sc administration of capsaicin in increasing doses (350, 700, 1,400, 2,100, and 2,800 micrograms) on 5 consecutive days. When adult, 9 treated and 5 control rats were chronically implanted with a lateral intracerebrovent...

journal_title：Behavioral neuroscience

authors： Dib B

更新日期：1983-10-01 00:00:00

abstract：:New Zealand male rabbits (Oryctolagus cuniculus) were trained on a trace eyeblink conditioning paradigm using a 250-ms tone conditioned stimulus, a 100-ms airpuff unconditioned stimulus, and a 500-ms trace interval. Rabbits received bilateral hippocampal aspirations either 1 day or 1 month after learning. Controls con...

journal_title：Behavioral neuroscience

authors： Kim JJ,Clark RE,Thompson RF

更新日期：1995-04-01 00:00:00

abstract：:Studies have shown that noxious cutaneous stimulation engages physiologically different antinociceptive systems to inhibit a spinal reflex, tail withdrawal from radiant heat. Two experiments are reported that examine the relationship between the inhibition of the tail-flick response and brain-mediated responses to noc...

journal_title：Behavioral neuroscience

authors： Crown ED,Grau JW,Meagher MW

更新日期：2004-12-01 00:00:00

abstract：:In previous studies the cerebellar interpositus (IP) nucleus, but not the hippocampus, was shown to be necessary both for initial learning and retention and for long-term retention of the standard delay eyeblink conditioned response (CR). However, in the trace eyeblink CR procedure, the hippocampus is also necessary f...

journal_title：Behavioral neuroscience

authors： Pakaprot N,Kim S,Thompson RF

更新日期：2009-02-01 00:00:00

abstract：:Parametric manipulations of the task demand were used to examine the role of the hippocampus and amygdala in nonspatial and spatial working memory in rats. Hippocampal lesions produced an immediate and long-lasting impairment of nonspatial working memory in an operant task. The memory deficits increased as the delay i...

journal_title：Behavioral neuroscience

authors： Wan RQ,Pang K,Olton DS

更新日期：1994-10-01 00:00:00

abstract：:Idazoxan, an alpha 2 adrenoceptor antagonist (2 mg/kg), enhanced novel object investigation in a holeboard in rats as previously reported (V. Devauges & S. J. Sara, 1990). Two weeks of 10 min/day in 37 degrees C water increased dopamine-beta-hydroxylase staining density in the locus coeruleus but did not enhance novel...

journal_title：Behavioral neuroscience

authors： Mansour AA,Babstock DM,Penney JH,Martin GM,McLean JH,Harley CW

更新日期：2003-06-01 00:00:00

abstract：:The present study tested the prediction that D-cycloserine (DCS), a partial N-methyl-D-aspartate agonist, would facilitate extinction of conditioned freezing in male Sprague-Dawley rats. Rats received 5 light-shock pairings (conditioning). The following day, rats received 6 light-alone presentations (extinction traini...

journal_title：Behavioral neuroscience

authors： Ledgerwood L,Richardson R,Cranney J

更新日期：2003-04-01 00:00:00

abstract：:Previous research (Grau, 1987a, 1987b) suggests that forebrain systems play an essential role in the hypoalgesia observed after brief shock but not long shock. Additional research has shown that pentobarbital anesthesia and decerebration block the hypoalgesia observed after 3 brief (0.75-s) shocks but not the hypoalge...

journal_title：Behavioral neuroscience

authors： Meagher MW,Grau JW,King RA

更新日期：1989-12-01 00:00:00

abstract：:Activation of memory retrieval after weak learning (WL), during either the short- or intermediate-term stages of memory in day-old chickens, resulted in the strengthening of the memory to levels normally associated with strong learning. Administration of the calcium channel antagonist lanthanum chloride, the glutamate...

journal_title：Behavioral neuroscience

authors： Summers MJ,Crowe SF,Ng KT

更新日期：2000-08-01 00:00:00

abstract：:The present experiment monitored bilateral eyelid responses during eyeblink conditioning in rats trained with a unilateral unconditioned stimulus (US). Three groups of rats were used to determine if cross-modal savings occurs when the location of the US is switched from one eye to the other. Rats in each group first r...

journal_title：Behavioral neuroscience

authors： Campolattaro MM,Buss EW,Freeman JH

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:Caffeine is frequently consumed concurrent to or immediately following ethanol consumption. Identifying how caffeine and ethanol interact to modulate behavior is essential to understanding the co-use of these drugs. The plus-maze discriminative avoidance task (PMDAT) allows within-subject measurement of le...

journal_title：Behavioral neuroscience

authors： Gulick D,Gould TJ

更新日期：2009-12-01 00:00:00

abstract：:In contrast to humans, sodium-replete rats prefer dilute saline to water and do not prefer salted food to plain food. Sodium depletion is known to enhance the intake of and preference for salt provided in water. Here, we examined whether the context of the delivery vehicle for salt could influence salt intake and pref...

journal_title：Behavioral neuroscience

authors： Bertino M,Tordoff MG

更新日期：1988-08-01 00:00:00

abstract：:Electrolytic microlesions aimed at the dorsomedial portion of the ventromedial nucleus (VMN) of the hypothalamus were generated, and effects on copulation, 50-kHz vocalizations, scent marking, and sexual motivation were measured. Male rats were tested before and after lesions, after castration, and after testosterone ...

journal_title：Behavioral neuroscience

authors： Harding SM,McGinnis MY

更新日期：2005-10-01 00:00:00

abstract：:Reward uncertainty is a common characteristic of gambling and may powerfully enhance attraction to gambling-related cues, thus promoting maladaptive gambling behaviors in susceptible individuals. The co-occurrence of gambling disorder with tobacco use disorder (60.4%) suggests a common mechanism for their pathology, a...

journal_title：Behavioral neuroscience

authors： Russell TI,Robinson MJF

更新日期：2019-08-01 00:00:00

abstract：:The role of the thalamus in memory is potentially very complex. However, most studies on the memory impairments of thalamic lesions have focused on retrospective memory, rarely on prospective memory. To explore the effect of thalamic lesions on event-based prospective memory (EBPM) and time-based prospective memory (T...

journal_title：Behavioral neuroscience

authors： Cheng H,Tian Y,Hu P,Wang J,Wang K

更新日期：2010-02-01 00:00:00

abstract：:Rats received kindling stimulations to the perirhinal cortex (PRh), ventral hippocampus (VH), or dorsal hippocampus (DH) in 1 environment and an equivalent number of sham stimulations in a 2nd environment. The PRh-kindled rats displayed rapid kindling and a swift emergence of conditioned interictal defensiveness. In c...

journal_title：Behavioral neuroscience

authors： Barnes SJ,Hua JM,Pinel JP,Takahashi A,Wig GS

更新日期：2005-12-01 00:00:00

abstract：:Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway...

journal_title：Behavioral neuroscience

authors： Reeves TM,Smith DC

更新日期：1987-04-01 00:00:00

abstract：:The amygdala is an integrator of affective processing, and a key component of a network regulating social behavior. While decades of lesion studies in nonhuman primates have shown alterations in social interactions after amygdala damage, acute manipulations of the amygdala in primates have been underexplored. We recen...

journal_title：Behavioral neuroscience

authors： Forcelli PA,Wellman LL,Malkova L

更新日期：2017-04-01 00:00:00

abstract：:Norway rat pups were either handled (H) or undisturbed (nonhandled, NH) in the period between birth and weaning on Day 21. Following weaning, half of the animals in each group were housed socially (Soc), and half were housed in isolation (Isol). At 120-150 days of age, all animals were sacrificed, and the following re...

journal_title：Behavioral neuroscience

authors： Meaney MJ,Aitken DH,Bodnoff SR,Iny LJ,Tatarewicz JE,Sapolsky RM

更新日期：1985-08-01 00:00:00

abstract：:Transecting the corpus callosum of postnatal day (P)1-6 rats disinhibits the production of spindle bursts (SBs) within primary somatosensory cortex (S1), most notably during periods of sleep-related myoclonic twitching. Here we investigated developmental changes in this callosally mediated disinhibition and its associ...

journal_title：Behavioral neuroscience

authors： Marcano-Reik AJ,Prasad T,Weiner JA,Blumberg MS

更新日期：2010-10-01 00:00:00