Abstract:
:The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout training. The experiments in the present study tested the hypothesis that disruption of cingulothalamic stimulus processing produced by lesions of the MD would impair 2 types of associative learning that involve decremental changes in attention. In Experiment 1, MD lesions severely impaired blocking. In Experiment 2, MD lesions severely impaired LI. The results indicate that lesions of the MD impair incremental, decremental, or both types of changes in stimulus processing during learning.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Nicholson DA,Freeman JH Jrdoi
10.1037//0735-7044.116.2.276subject
Has Abstractpub_date
2002-04-01 00:00:00pages
276-85issue
2eissn
0735-7044issn
1939-0084journal_volume
116pub_type
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