Abstract:
:Behavioral changes induced by inescapable shock were examined in six strains of mice. Exposure to shock provoked time-dependent disturbances of shuttle escape performance. In some strains the shock treatment did not affect escape performance, whereas in others profound performance deficits were evident. The inescapable shock treatment likewise induced strain-dependent alterations of performance in a forced-swim task. In most instances the shock treatment initially provoked invigorated responding, but in other strains the shock had no effect or depressed active responding. Finally, Y-maze spontaneous alteration performance was not affected by the shock treatment, although a strain-dependent increase of perseverative responses was evident. The occurrence of a stressor-induced deficit in one task in a particular strain of mouse was not predictive of behavioral alterations in a second task. These data are discussed with respect to animal models of depression and genetic differences associated with the response to stressors.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Shanks N,Anisman Hdoi
10.1037//0735-7044.102.6.894subject
Has Abstractpub_date
1988-12-01 00:00:00pages
894-905issue
6eissn
0735-7044issn
1939-0084journal_volume
102pub_type
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更新日期:2001-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1037/0735-7044.117.6.1423
更新日期:2003-12-01 00:00:00
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更新日期:2014-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:1984-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.3.552
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doi:10.1037//0735-7044.117.1.184
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0034653
更新日期:2013-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1037/0735-7044.118.4.730
更新日期:2004-08-01 00:00:00
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journal_title:Behavioral neuroscience
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更新日期:2016-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.6.1313
更新日期:1997-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:1997-04-01 00:00:00
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journal_title:Behavioral neuroscience
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更新日期:2013-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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