Modulation of memory consolidation for olfactory learning by reversible inactivation of the basolateral amygdala.

Abstract:

:The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent more time near the odor, and reacted differently on contact with the odor when tested 24 hr after training, than did rats receiving paired presentations and saline infusions, but they did not differ from rats receiving unpaired presentations and saline infusions. The results indicate that the BLA plays a similar role in influencing consolidation of olfactory-based memory as it does for memory based on other modalities. Thus, these findings strengthen the view that the BLA plays a general role in modulation of memory storage for emotionally arousing events.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Kilpatrick L,Cahill L

doi

10.1037//0735-7044.117.1.184

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

184-8

issue

1

eissn

0735-7044

issn

1939-0084

journal_volume

117

pub_type

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