Selective immunotoxic lesions of basal forebrain cholinergic neurons: twenty years of research and new directions.

abstract：:Rats emit aversive taste reactivity (TR) behavior (i.e., gapes) following intraoral delivery of a cocaine-paired taste cue and greater conditioned aversive TR at the end of training predicts greater drug-seeking and taking. Here, we examined the development of this conditioned aversive TR behavior on a trial-by-trial ...

journal_title：Behavioral neuroscience

authors： Colechio EM,Imperio CG,Grigson PS

更新日期：2014-04-01 00:00:00

abstract：:In previous studies the cerebellar interpositus (IP) nucleus, but not the hippocampus, was shown to be necessary both for initial learning and retention and for long-term retention of the standard delay eyeblink conditioned response (CR). However, in the trace eyeblink CR procedure, the hippocampus is also necessary f...

journal_title：Behavioral neuroscience

authors： Pakaprot N,Kim S,Thompson RF

更新日期：2009-02-01 00:00:00

abstract：:The basal ganglia and the cerebellum are anatomically and functionally linked to the cerebral cortex through a series of well-established circuits. The disruption of dopaminergic projections in Parkinson's disease (PD) leads to an imbalance within these circuits, leading to motor and cognitive symptoms. The cortico-ce...

journal_title：Behavioral neuroscience

authors： Martinu K,Monchi O

更新日期：2013-04-01 00:00:00

abstract：:The spontaneously hypertensive rat (SHR) has been suggested as a possible animal model of attention-deficit/hyperactivity disorder (ADHD). Reductions in the volume of the cerebellum and impairments in cerebellar-dependent eyeblink conditioning have been observed in ADHD, prompting investigation into whether SHRs also ...

journal_title：Behavioral neuroscience

authors： Chess AC,Green JT

更新日期：2008-02-01 00:00:00

abstract：:The acoustic startle reflex (ASR) in rats is attenuated by a light paired with food or, in humans, by "pleasant" pictures. Rats were trained to barpress for lateral hypothalamus (LH) stimulation. ASR amplitudes were then measured at 4 intensities, with or without a light. Control rats that did not receive brain-stimul...

journal_title：Behavioral neuroscience

authors： Steidl S,Li L,Yeomans JS

更新日期：2001-06-01 00:00:00

abstract：:Repeated exposure to female-related stimuli causes functional alterations in the neural circuitry mediating male rat sexual behavior. In a study published in the current issue of this journal, G. M. Lagoda, J. W. Muschamp, A. Vigdorchik, and E. M. Hull (2004) provide interesting new evidence as to the mechanisms respo...

journal_title：Behavioral neuroscience

authors： Coolen LM

更新日期：2004-12-01 00:00:00

abstract：:Classical conditioning is known to induce frequency-specific receptive field (RF) plasticity in the auditory cortex (ACx). This study determined the effects of discrimination training on RFs at two levels of task difficulty. Single unit and cluster discharges were recorded in the ACx of adult guinea pigs trained in a ...

journal_title：Behavioral neuroscience

authors： Edeline JM,Weinberger NM

更新日期：1993-02-01 00:00:00

abstract：:Recent evidence suggests that underlying patterns of cortical activation may partially account for individual differences in susceptibility to the effects of sleep deprivation. Here, functional magnetic resonance imaging (fMRI) was used to examine the activation of military pilots whose sleep-deprivation vulnerability...

journal_title：Behavioral neuroscience

authors： Caldwell JA,Mu Q,Smith JK,Mishory A,Caldwell JL,Peters G,Brown DL,George MS

更新日期：2005-06-01 00:00:00

abstract：:The effects of exogenous and endogenous steroids on components of female sexual behavior of neonatal male and female rats were investigated. In Experiment 1, 4-day-old rats were treated with 0, 0.1, 1.0, 10, or 100 micrograms/10 g body weight estradiol benzoate (EB) and were tested 44 hr later. In Experiment 2, male r...

journal_title：Behavioral neuroscience

authors： Williams CL

更新日期：1987-10-01 00:00:00

abstract：:Whether olfactory working memory involves verbal representations or neural images of odor per se remains unclear. This study investigated whether verbal representation influences performance in an olfactory delayed-match-to-sample task and used monorhinal presentation to generate hypotheses as to the underlying anatom...

journal_title：Behavioral neuroscience

authors： Yeshurun Y,Dudai Y,Sobel N

更新日期：2008-10-01 00:00:00

abstract：:The influence of water deprivation on hippocampal long-term potentiation (LTP), theta rhythm, and contextual fear conditioning in rats was examined. In Experiment 1, hippocampal EEG activity and perforant path LTP were assessed in pentobarbital-anesthetized rats. Water deprivation did not affect baseline cell excitabi...

journal_title：Behavioral neuroscience

authors： Maren S,DeCola JP,Swain RA,Fanselow MS,Thompson RF

更新日期：1994-02-01 00:00:00

abstract：:It has been proposed that the cognitive dysfunction observed in patients with schizophrenia reflects a failure in cognitive control, in particular an inability to use task-relevant information to guide behavior. Using a prefrontal-dependent task designed to reflect aspects of cue and response conflict seen in human co...

journal_title：Behavioral neuroscience

authors： Haddon JE,Killcross S

更新日期：2011-06-01 00:00:00

abstract：:This review focuses on research on both the neural substrate of maternal responsiveness and on the physiological, behavioral, and motivational adaptations to the maternal state. The female's response to her young is presented as a model motivational system and the mechanisms and neural circuitry through which the medi...

journal_title：Behavioral neuroscience

authors： Numan M,Woodside B

更新日期：2010-12-01 00:00:00

abstract：:Gerbils aged 3 months and 24+ months were subjected to 5 min of global forebrain ischemia and tested in a radial arm maze (1 trial/day, 50 days). Compared with age-matched, sham-operated controls, ischemic animals were impaired on measures of both working and reference memory. Aged animals were impaired on working mem...

journal_title：Behavioral neuroscience

authors： Schwartz C,Wishart TB,Ijaz S,Shuaib A

更新日期：1998-08-01 00:00:00

abstract：:Lurcher mutant (+/Lc) mice exhibit a massive loss of neurons in the cerebellar cortex and in the inferior olivary nucleus while deep cerebellar nuclei are essentially intact. To discriminate the respective participation of the cerebellar cortex and deep structures in learning and memory, the authors subjected 3- to 6-...

journal_title：Behavioral neuroscience

authors： Caston J,Vasseur F,Delhaye-Bouchaud N,Mariani J

更新日期：1997-02-01 00:00:00

abstract：:Six females rats were trained to lever press under a free operant shock-postponement schedule. Each subject had a yoked control which received shock whenever the subject did. The shock-postponement interval (R-S) was varied from 5, 10, 20, 40, to 80 s over blocks of sessions. Corticosteroid levels were taken prior to ...

journal_title：Behavioral neuroscience

authors： Herrmann TF,Hurwitz HM,Levine S

更新日期：1984-12-01 00:00:00

abstract：:Attention-deficit hyperactivity disorder (ADHD) may be caused by genetic or environmental factors. Among environmental factors, perinatal complications are related, such as neonatal hypoxia-ischemia (HI). Thus, the aim of this study was to investigate whether HI contributes to the development of characteristics relate...

journal_title：Behavioral neuroscience

authors： Miguel PM,Schuch CP,Rojas JJ,Carletti JV,Deckmann I,Martinato LH,Pires AV,Bizarro L,Pereira LO

更新日期：2015-06-01 00:00:00

abstract：:Covert shifts of visual attention in space have been quantified by measuring the effects of visual cues on the detection of visual targets in humans and monkeys maintaining visual fixation. These observations of "covert orienting" have provided important information regarding the neurobiology of visual attention in pr...

journal_title：Behavioral neuroscience

authors： Bushnell PJ

更新日期：1995-12-01 00:00:00

abstract：:Many studies have pointed to vulnerability to stress and stress-related pathologies at different timepoints during an individual's life span. These sensitive windows are usually during periods of neural development, such as embryogenesis, infancy, and adolescence. It is critical to understand how neural circuitry may ...

journal_title：Behavioral neuroscience

authors： Argue KJ,Neckameyer WS

更新日期：2013-10-01 00:00:00

abstract：:The striatum is implicated in response selection and performance, the dorsal striatum in sensorimotor control and habit learning, and the ventral striatum in motivation and rewarded behaviors. Ventral striatal lesions produce performance changes on food-reinforced, progressive-ratio (PR) schedules, but the effects of ...

journal_title：Behavioral neuroscience

authors： Eagle DM,Humby T,Dunnett SB,Robbins TW

更新日期：1999-08-01 00:00:00

abstract：:Lesion studies have shown that the avian hippocampus plays a crucial role in homing pigeon (Columba livia) navigation. Using the expression of the immediate early gene protein ZENK in intact pigeons, the authors found regional variation in hippocampal activation as a consequence of homing and, necessarily, the behavio...

journal_title：Behavioral neuroscience

authors： Shimizu T,Bowers AN,Budzynski CA,Kahn MC,Bingman VP

更新日期：2004-08-01 00:00:00

abstract：:Previous results from our laboratory have demonstrated that 3-day-old rats given dopamine (DA)-depleting brain lesions are spared the severe behavioral dysfunctions seen after comparable brain damage in adults. This behavioral sparing is accompanied by a sprouting of serotonin (5-HT)-containing neurons in the striatum...

journal_title：Behavioral neuroscience

authors： Bruno JP,Jackson D,Zigmond MJ,Stricker EM

更新日期：1987-12-01 00:00:00

abstract：:Young and aged animals were tested on a spatial alternation task that consisted of two interleaved components: (1) an "outbound" or alternation component (working memory) and (2) an "inbound" component, requiring the animal to remember to return to a central location in space (spatial memory). In the present study, ag...

journal_title：Behavioral neuroscience

authors： Kapellusch AJ,Lester AW,Schwartz BA,Smith AC,Barnes CA

更新日期：2018-12-01 00:00:00

abstract：:Mice unable to synthesize dopamine (DA) in dopaminergic neurons were generated by gene-targeting techniques (Q.-Y. Zhou & R. D. Palmiter, 1995). These dopamine-deficient (DA-/-) mice required daily administration of 3,4-dihydroxyphenylalanine (L-DOPA) for survival beyond 2 to 3 weeks of age. This treatment stimulated ...

journal_title：Behavioral neuroscience

authors： Szczypka MS,Zhou QY,Palmiter RD

更新日期：1998-10-01 00:00:00

abstract：:Gerbils show a postischemic increase in locomotor activity that correlates to the extent of neuron loss in the hippocampal CA1 subfield. It has been suggested that this hyperactivity is predictive of neuron loss in the CA1. In this study the correlation between postischemic hyperactivity and neuron loss in several hip...

journal_title：Behavioral neuroscience

authors： Andersen MB,Zimmer J,Sams-Dodd F

更新日期：1997-12-01 00:00:00

abstract：:Quipazine is a 5-HT2A-receptor agonist that has been used to induce motor activity and promote recovery of function after spinal cord injury in neonatal and adult rodents. Sensory stimulation also activates sensory and motor circuits and promotes recovery after spinal cord injury. In rats, tail pinching is an effectiv...

journal_title：Behavioral neuroscience

authors： Swann HE,Kauer SD,Allmond JT,Brumley MR

更新日期：2017-02-01 00:00:00

abstract：:Finicky feeding refers to an animal's tendency to become more particular in accepting and choosing food as satiation is approached. We tested the hypothesis that finickiness in the blowfly is related to the balance between internal inhibition, generated by a full crop, and external sensory information, generated by or...

journal_title：Behavioral neuroscience

authors： Moss CF,Dethier VG

更新日期：1983-08-01 00:00:00

abstract：:The kinematic parameters of air-stepping induced by 2 methods known to elicit locomotion (olfactory stimulation vs. L-dopa injection) were compared in 3-day-old rats. In the 1st stage, suspended pups were induced to step with an olfactory stimulus of soiled shavings from the nest. In the 2nd stage, they received a sub...

journal_title：Behavioral neuroscience

authors： Jamon M,Maloum I,Riviere G,Bruguerolle B

更新日期：2002-12-01 00:00:00

abstract：:The medial division of the medial geniculate body (MGm) projects to the lateral amygdala and the upper layer of auditory cortex and develops physiological plasticity rapidly during classical conditioning. The effects of learning on frequency receptive fields (RFs) in the MGm of the guinea pig have been determined. Cla...

journal_title：Behavioral neuroscience

authors： Edeline JM,Weinberger NM

更新日期：1992-02-01 00:00:00

abstract：:In the cognitive mapping theory of hippocampal function, currently active place cells represent a rat's spatial location (J. O'Keefe & L. Nadel, 1978). A systematic shift of firing field locations should therefore produce a similar shift in a rat's judgment of its location. A. A. Fenton, G. Csizmadia, and R. U. Muller...

journal_title：Behavioral neuroscience

authors： Kubie JL,Fenton A,Novikov N,Touretzky D,Muller RU

更新日期：2007-08-01 00:00:00