Cortico-basal ganglia and cortico-cerebellar circuits in Parkinson's disease: pathophysiology or compensation?

abstract：:The acoustic startle reflex (ASR) in rats is attenuated by a light paired with food or, in humans, by "pleasant" pictures. Rats were trained to barpress for lateral hypothalamus (LH) stimulation. ASR amplitudes were then measured at 4 intensities, with or without a light. Control rats that did not receive brain-stimul...

journal_title：Behavioral neuroscience

authors： Steidl S,Li L,Yeomans JS

更新日期：2001-06-01 00:00:00

abstract：:Previous research conducted in monkeys and rats has established that the perirhinal cortex is critically involved in object- or stimulus-recognition memory, whereas other research suggests this region may contribute to memory for object discriminations. These findings do not rule out the possibility that the perirhina...

journal_title：Behavioral neuroscience

authors： Wiig KA,Burwell RD

更新日期：1998-08-01 00:00:00

abstract：:Rats with bilateral, electrolytic lesions of perirhinal cortex (PRC), lateral entorhinal cortex (LEC), or combined lesions (PRLE) were impaired relative to controls (sham) during initial acquisition in the Morris water maze, although all groups were eventually able to learn to locate the platform. A further deficit in...

journal_title：Behavioral neuroscience

authors： Liu P,Bilkey DK

更新日期：1998-04-01 00:00:00

abstract：:Dopaminergic blocking agents have been known to suppress intracranial self-stimulation, but whether the suppression results from a reduction in the rewarding value of stimulation or from motor deficits has remained controversial. We have resolved this controversy by developing an operant technique minimally dependent ...

journal_title：Behavioral neuroscience

authors： Fantie BD,Nakajima S

更新日期：1987-10-01 00:00:00

abstract：:Estrogens have been shown to rapidly promote male copulatory behaviors with a time-course that suggests rapid signaling events are involved. The present study tested the hypothesis that estrogen acts through a novel Gq protein-coupled membrane estrogen receptor (ER). Thus, either estradiol (E2), STX (a diphenylacrylam...

journal_title：Behavioral neuroscience

authors： Kaufman KR,Kelly MJ,Roselli CE

更新日期：2013-08-01 00:00:00

abstract：:Caffeine is a psychostimulant frequently consumed by adults and children, often in combination with high levels of sugar. Chronic pretreatment with either substance can amplify both amphetamine and cocaine-induced hyperactivity in rodents. The present study sought to elucidate whether age at the time of exposure to su...

journal_title：Behavioral neuroscience

authors： Franklin JL,Wearne TA,Homewood J,Cornish JL

更新日期：2017-08-01 00:00:00

abstract：:This study determined the effects of estrogen loss and replacement therapy on learning and memory function in monkeys (Macaca fascicularis). The ability to learn, remember, and perform reversals of object discriminations and the accuracy on a spatial delayed response task were found to be comparable in young adult sur...

journal_title：Behavioral neuroscience

authors： Voytko ML

更新日期：2000-12-01 00:00:00

abstract：:Substantial evidence suggests that pharmacological manipulations of neural serotonin pathways influence ingestive behaviors. Despite the known role of the nucleus accumbens in directing appetitive and consummatory behavior, there has been little examination of the influences that serotonin receptors may play in modula...

journal_title：Behavioral neuroscience

authors： Pratt WE,Blackstone K,Connolly ME,Skelly MJ

更新日期：2009-10-01 00:00:00

abstract：:Female songbirds use male songs as an important criterion for mate selection. Several studies have reported that female songbirds prefer complex songs to other song types. In a recent study, the authors found that song responsiveness in female zebra finches (Taeniopygia guttata) is strongly modulated by circulating es...

journal_title：Behavioral neuroscience

authors： Vyas A,Harding C,McGowan J,Snare R,Bogdan D

更新日期：2008-10-01 00:00:00

abstract：:A modified learned food aversion paradigm simulated the prolonged food and illness exposure likely to characterize nutrient deficiencies or tumor growth. In this paradigm, a continuously available food was associated with a slow, continuous infusion of LiCl provided by osmotic minipump. Significant aversions were acqu...

journal_title：Behavioral neuroscience

authors： Bernstein IL,Goehler LE

更新日期：1983-04-01 00:00:00

abstract：:A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...

journal_title：Behavioral neuroscience

authors： Hotsenpiller G,Horak BT,Wolf ME

更新日期：2002-08-01 00:00:00

abstract：:Anterograde amnesia (AA), forgetting of events that occur following a traumatic episode, has recently been demonstrated by using a mild decrease in temperature (hypothermia) as the amnestic agent. However, no data currently exist to indicate if an increase in body temperature (hyperthermia) might affect memory process...

journal_title：Behavioral neuroscience

authors： Ahlers ST,Riccio DC

更新日期：1987-06-01 00:00:00

abstract：:In previous studies using moveable electrodes to map the substrate for brain stimulation reward, reward effectiveness was estimated by varying either the current or the number of pulses per train. The resulting relationship between reward effectiveness and stimulation site is independent of the fixed parameter only if...

journal_title：Behavioral neuroscience

authors： Forgie ML,Shizgal P

更新日期：1993-06-01 00:00:00

abstract：:Appetitive behaviors of rats were monitored in a runway situation following central infusions of neuroactive substances into brain areas implicated in electrical self-stimulation. Microinjections of the dopamine antagonist cis-flupentixol or the cholinergic antagonist atropine into the nucleus accumbens (Acb) severely...

journal_title：Behavioral neuroscience

authors： Ikemoto S,Panksepp J

更新日期：1996-04-01 00:00:00

abstract：:The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent m...

journal_title：Behavioral neuroscience

authors： Kilpatrick L,Cahill L

更新日期：2003-02-01 00:00:00

abstract：:The context preexposure facilitation effect (CPFE) is a variant of contextual fear conditioning in which context learning, context-shock association, and expression of context conditioning occur in 3 separate phases-preexposure, training, and testing. During the preexposure phase, the CPFE is disrupted by hippocampal ...

journal_title：Behavioral neuroscience

authors： Robinson-Drummer PA,Dokovna LB,Heroux NA,Stanton ME

更新日期：2016-04-01 00:00:00

abstract：:Active sleep (AS), as measured by the occurrence of myoclonic twitching (MT), is the most prevalent behavioral state in newborn rats. Historically, AS has been considered a developmental precursor of REM sleep, but recently this idea has been questioned. In the present study, the authors assess, in 2-, 5-, and 8-day-o...

journal_title：Behavioral neuroscience

authors： Karlsson KA,Blumberg MS

更新日期：2002-10-01 00:00:00

abstract：:Previous research (Grau, 1987a, 1987b) suggests that forebrain systems play an essential role in the hypoalgesia observed after brief shock but not long shock. Additional research has shown that pentobarbital anesthesia and decerebration block the hypoalgesia observed after 3 brief (0.75-s) shocks but not the hypoalge...

journal_title：Behavioral neuroscience

authors： Meagher MW,Grau JW,King RA

更新日期：1989-12-01 00:00:00

abstract：:To test whether habituation is specific to the stimulus modality, the authors analyzed cross-habituation between the tactile startle response' (TSR) and the acoustic startle response (ASR). The acoustic artifacts of airpuffs used to elicit the TSR were reduced by using a silencer and were effectively masked by backgro...

journal_title：Behavioral neuroscience

authors： Pilz PK,Carl TD,Plappert CF

更新日期：2004-10-01 00:00:00

abstract：:Male prairie voles (Microtus ochrogaster) form a pair bond with a female partner after mating, and this behavior is regulated by the neuropeptide vasopressin (AVP). The authors report that AVP in the lateral septum is important for pair bond formation. Administration of an AVP V1a receptor antagonist in the lateral se...

journal_title：Behavioral neuroscience

authors： Liu Y,Curtis JT,Wang Z

更新日期：2001-08-01 00:00:00

abstract：:Two experiments used an associative blocking design to study the role of dopamine receptors in the nucleus accumbens shell (AcbSh) and core (AcbC) in fear prediction error. Rats in the experimental groups were trained to a visual fear-conditioned stimulus (conditional stimulus [CS]) A in Stage I, whereas rats in the c...

journal_title：Behavioral neuroscience

authors： Li SS,McNally GP

更新日期：2015-08-01 00:00:00

abstract：:Gerbils aged 3 months and 24+ months were subjected to 5 min of global forebrain ischemia and tested in a radial arm maze (1 trial/day, 50 days). Compared with age-matched, sham-operated controls, ischemic animals were impaired on measures of both working and reference memory. Aged animals were impaired on working mem...

journal_title：Behavioral neuroscience

authors： Schwartz C,Wishart TB,Ijaz S,Shuaib A

更新日期：1998-08-01 00:00:00

abstract：:Experimental data and computational models suggest that blockade of muscarinic cholinergic receptors impairs paired-associate learning and increases proactive interference (E. DeRosa & M. E. Hasselmo, 2000; M. E. Hasselmo & J. M. Bower, 1993). The results presented here provide evidence in humans supporting these hypo...

journal_title：Behavioral neuroscience

authors： Atri A,Sherman S,Norman KA,Kirchhoff BA,Nicolas MM,Greicius MD,Cramer SC,Breiter HC,Hasselmo ME,Stern CE

更新日期：2004-02-01 00:00:00

abstract：:Fifty-eight 4-day-old male rats were studied. Peripheral desensitization was induced in 36 rats by sc administration of capsaicin in increasing doses (350, 700, 1,400, 2,100, and 2,800 micrograms) on 5 consecutive days. When adult, 9 treated and 5 control rats were chronically implanted with a lateral intracerebrovent...

journal_title：Behavioral neuroscience

authors： Dib B

更新日期：1983-10-01 00:00:00

abstract：:Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway...

journal_title：Behavioral neuroscience

authors： Reeves TM,Smith DC

更新日期：1987-04-01 00:00:00

abstract：:In male rats with food and water freely available, the specific dopamine D2 antagonist YM-09151-2 had little effect on total food or water intake across a 24-hr period. However, it produced a substantial dose-related decrease in feeding rate during meals and an enhancement of both meal size and duration. The equivalen...

journal_title：Behavioral neuroscience

authors： Clifton PG,Rusk IN,Cooper SJ

更新日期：1991-04-01 00:00:00

abstract：:Cognitive functions, such as working memory, are disrupted in most psychiatric disorders. Many of these processes are believed to depend on the medial prefrontal cortex (mPFC). Traditionally, maze-based behavioral tasks, which have a strong exploratory component, have been used to study the role of the mPFC in working...

journal_title：Behavioral neuroscience

authors： Benoit LJ,Holt ES,Teboul E,Taliaferro JP,Kellendonk C,Canetta S

更新日期：2020-06-01 00:00:00

abstract：:The estradiol (E2), estrogen receptor-α (ERα), testosterone (T), and androgen receptor (AR) can contribute to anxiety, but whether they are associated with the reversion of prenatal adverse outcomes remains unclear. Here, we tested the interactive effects of prenatal maternal restraint stress and early postnatal short...

journal_title：Behavioral neuroscience

authors： He FQ,Fang G,Wang B,Guo XJ,Guo CL

更新日期：2015-12-01 00:00:00

abstract：:Circadian rhythms in most mammals are synchronized to local time by phase and period resetting actions of daily light-dark cycles on a retino-recipient, light-entrainable circadian pacemaker, the suprachiasmatic nucleus (SCN). The SCN receives input from other brain regions, some of which mediate the phase and period ...

journal_title：Behavioral neuroscience

authors： Webb IC,Antle MC,Mistlberger RE

更新日期：2014-06-01 00:00:00

abstract：:Rats with perirhinal cortex lesions were sequentially trained in a rectangular water tank on a series of 3 visual discriminations, each between mirror-imaged stimuli. When these same discriminations were tested concurrently, the rats were forced to use a configural strategy to solve the problems effectively. There was...

journal_title：Behavioral neuroscience

authors： Aggleton JP,Albasser MM,Aggleton DJ,Poirier GL,Pearce JM

更新日期：2010-02-01 00:00:00