Abstract:
:A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain regions analyzed. In contrast, pairing of cocaine with generalized contextual cues (whole room) produced conditioned locomotion and Fos activation in the prelimbic portion of prefrontal cortex and the nucleus accumbens core. These results suggest that the pattern of neuronal activation during cocaine-conditioned activity differs depending on whether a discrete or contextual stimulus is used as a conditioned stimulus. The possibility that expectancy and frustrative nonreward contribute to Fos expression in rats conditioned to contextual cues is discussed.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Hotsenpiller G,Horak BT,Wolf MEsubject
Has Abstractpub_date
2002-08-01 00:00:00pages
634-45issue
4eissn
0735-7044issn
1939-0084journal_volume
116pub_type
杂志文章abstract::The defensive withdrawal reflex of the mantle organs (gill, siphon, and mantle shelf) of the marine mollusc Aplysia californica has been the subject of numerous studies investigating the cellular and molecular mechanisms of learning. In behavioral experiments, the reflex has been monitored by means of two different re...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.2.292
更新日期:1987-04-01 00:00:00
abstract::The present study examined the effects of lesions of the central nucleus of the amygdala (CeA) on the acquisition of a new response with conditioned reinforcement (CR) and its potentiation by intra-accumbens infusions of d-amphetamine (1, 3, 10, and 20 microg/microl). Rats were trained to associate a light-plus-noise ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.5.981
更新日期:1996-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0017128
更新日期:2009-10-01 00:00:00
abstract::The experiments addressed the question of whether certain modalities of stimulation are more effective in eliciting immobility-related, atropine-sensitive neocortical low-voltage fast activity and hippocampal rhythmical slow activity from the rabbit. More pronounced activation and less pronounced habituation followed ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.98.2.333
更新日期:1984-04-01 00:00:00
abstract::The hippocampal formation (comprising the hippocampus proper, the dentate gyrus, and the subiculum) has been repeatedly implicated in information storage models of the mammalian brain. The precise nature of the hippocampal role in the storage of information has, however, remained elusive. Here it is proposed that the ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.100.2.147
更新日期:1986-04-01 00:00:00
abstract::Transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) from olfactory sensory neurons to the olfactory bulb as well as odor detection and discrimination were examined in rats in which each nasal epithelium had been irrigated with 0.1-0.5 ml 5% zinc sulfate. After treatment, rats showed few or no deficits ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::The influence of water deprivation on hippocampal long-term potentiation (LTP), theta rhythm, and contextual fear conditioning in rats was examined. In Experiment 1, hippocampal EEG activity and perforant path LTP were assessed in pentobarbital-anesthetized rats. Water deprivation did not affect baseline cell excitabi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.1.44
更新日期:1994-02-01 00:00:00
abstract::The role of the basolateral amygdala (BLA) in the consolidation of an association between an olfactory stimulus and footshock was investigated with a reversible lesion technique of post-training intra-BLA infusions of tetrodotoxin. Rats receiving tetrodotoxin infusions following paired odor-shock presentations spent m...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.117.1.184
更新日期:2003-02-01 00:00:00
abstract::Methylphenidate (MPD) is widely prescribed for attention-deficit/hyperactivity disorder in the United States. Patients, mostly school-age children, are taking the drug orally. To simulate the human condition, the authors used a cracker to administer methylphenidate orally (without the stress of handling) from Postnata...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.6.1272
更新日期:2007-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.5.873
更新日期:1997-10-01 00:00:00
abstract::Previous studies have identified a population of cells recorded in the postsubiculum and the anterior thalamic nucleus (ATN) that discharge as a function of an animal's head direction (HD) in the horizontal plane. The present experiments monitored HD cell activity when rats were confronted with a situation in which di...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.109.1.49
更新日期:1995-02-01 00:00:00
abstract::The female steroid hormone 17beta-estradiol enhances synaptic transmission and the magnitude of longterm potentiation (LTP) in adult rodent hippocampal slices. Long-term depression (LTD), another form of synaptic plasticity, occurs more prominently in hippocampal slices from aged rodents. A decrease in LTP has been re...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.122.2.301
更新日期:2008-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.115.1.165
更新日期:2001-02-01 00:00:00
abstract::This study investigated the effect of postnatal tactile stimulation (TS) on juvenile behavior, adult amphetamine (AMPH) sensitization, and the interaction of TS and AMPH on prefrontal cortical (PFC) thickness and striatum size. Pups received TS by stroking daily with a feather duster from birth till weaning and were t...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0022628
更新日期:2011-04-01 00:00:00
abstract::Chronic exposure to light at night (LAN) is a circadian disruptor and may be linked to various health risks, including mood disorders. We recently demonstrated that chronic exposure to dim (5 lux) LAN provokes depressive-like behaviors and reduced hippocampal CA1 dendritic spine density in female hamsters. Whether thi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0029699
更新日期:2012-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.2.331
更新日期:1996-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000142
更新日期:2016-06-01 00:00:00
abstract::Previous literature suggests that the hippocampus subserves processes associated with the encoding of novel information. To investigate the role of different subregions of the hippocampus, the authors made neurotoxic lesions in different subregions of the dorsal hippocampus (i.e., CA1, dentate gyrus [DG], or CA3) of r...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.119.1.145
更新日期:2005-02-01 00:00:00
abstract::Stages of formation of memory and the roles of different forebrain structures in memory formation were investigated by injecting various agents into the brains of chicks close to the time of peck-avoidance training. With L-glutamate injected bilaterally into the hyperstriatum 5 min pretraining, retention was good 1 mi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.100.6.856
更新日期:1986-12-01 00:00:00
abstract::The catechol-O-methyltransferase (COMT) val158met polymorphism has received attention in schizophrenia due to its role in prefrontal dopamine catabolism. Given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0026466
更新日期:2012-02-01 00:00:00
abstract::This experiment was conducted to determine whether the amount of preoperative training influences the effects, on retention, of amygdala lesions induced 30 days after escape training. Rats received 1 or 10 footshock-motivated escape training trials; 30 days later, sham or neurotoxic amygdala lesions were induced. Resu...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.6.1080
更新日期:1994-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.6.1067
更新日期:1993-12-01 00:00:00
abstract::Two experiments used an associative blocking design to study the role of dopamine receptors in the nucleus accumbens shell (AcbSh) and core (AcbC) in fear prediction error. Rats in the experimental groups were trained to a visual fear-conditioned stimulus (conditional stimulus [CS]) A in Stage I, whereas rats in the c...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000071
更新日期:2015-08-01 00:00:00
abstract::The behavior of fetal rats was examined on Day 19 of gestation with procedures that enabled chemical stimulation and direct observation of fetuses. Rat fetuses are sensitive to both tactile stroking and intraoral infusion of chemical solutions, but the pattern and amount of activity depend upon the modality of stimula...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.102.1.24
更新日期:1988-02-01 00:00:00
abstract::This review focuses on research on both the neural substrate of maternal responsiveness and on the physiological, behavioral, and motivational adaptations to the maternal state. The female's response to her young is presented as a model motivational system and the mechanisms and neural circuitry through which the medi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章,评审
doi:10.1037/a0021548
更新日期:2010-12-01 00:00:00
abstract::The authors demonstrated the efficacy of enriched housing conditions in promoting the behavioral recovery and neuronal survival following subicular lesion in rats. Chemical lesioning of the ventral subiculum impaired the spatial learning performances in rats. The lesion also induced a significant degree of neurodegene...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.3.491
更新日期:2007-06-01 00:00:00
abstract::Acetylcholine (ACh) and noradrenaline (NA) release in the olfactory bulb (OB) of ewes was monitored using microdialysis. Both ACh and NA release increased at parturition in multiparous but not in primiparous ewes. However, vaginocervical stimulation performed 6 hr postpartum induced an increase of ACh and NA release i...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.4.662
更新日期:1993-08-01 00:00:00
abstract::In Experiment 1, Long-Evans rat pups received fimbria-fornix transections or sham surgery on Postnatal Day 10 (PND10) and were then trained on PND23 to perform either a discrete-trials delayed alternation (DA) or a simple position discrimination (PD) task in a T maze. Rat pups in both surgical conditions learned the P...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.3.386
更新日期:1991-06-01 00:00:00
abstract::Food reinforcement, or the motivation to eat, has been associated with increased energy intake, greater body weight, and prospective weight gain. Much of the previous research on the reinforcing value of food has focused on the role of dopamine, but it may be worthwhile to examine genetic polymorphisms in the serotoni...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0032026
更新日期:2013-06-01 00:00:00
abstract::Many studies have pointed to vulnerability to stress and stress-related pathologies at different timepoints during an individual's life span. These sensitive windows are usually during periods of neural development, such as embryogenesis, infancy, and adolescence. It is critical to understand how neural circuitry may ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0033602
更新日期:2013-10-01 00:00:00