Effects of D-cycloserine on extinction of conditioned freezing.

abstract：:The authors examined the relationship between hippocampal theta activity and trace eyeblink conditioning. Hippocampal electrophysiological local field potentials were recorded before, during, and after conditioning or explicitly unpaired training sessions in adult male New Zealand White rabbits. As expected, a high re...

journal_title：Behavioral neuroscience

authors： Nokia MS,Penttonen M,Korhonen T,Wikgren J

更新日期：2009-06-01 00:00:00

abstract：:Reactivation of an already consolidated memory makes it labile for a period of several hrs, which are required for its reconsolidation. Evidence suggests that the return of conditioned fear through spontaneous recovery, reinstatement, or renewal can be prevented by blockading this reconsolidation process using pharmac...

journal_title：Behavioral neuroscience

authors： Meir Drexler S,Merz CJ,Hamacher-Dang TC,Marquardt V,Fritsch N,Otto T,Wolf OT

更新日期：2014-08-01 00:00:00

abstract：:The ontogeny of associative learning in delay (750-ms conditional stimulus [CS], 650-ms interstimulus interval [ISI]), long-delay (1,350-ms CS, 1,250-ms ISI), and trace (750-ms CS, 500-ms trace interval, 1,250-ms ISI) eyeblink conditioning was examined in 5-month-old human infants and adults. Infants and adults showed...

journal_title：Behavioral neuroscience

authors： Herbert JS,Eckerman CO,Stanton ME

更新日期：2003-12-01 00:00:00

abstract：:The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout traini...

journal_title：Behavioral neuroscience

authors： Nicholson DA,Freeman JH Jr

更新日期：2002-04-01 00:00:00

abstract：:The antinociceptive effects of signaled shock and its physiological underpinnings were examined in two experiments. In Experiment 1, rats were exposed to one of three shock conditions: no shock, unsignaled shock, and signaled (by a 10-s, 1000-Hz tone) shock. In each condition the rats were tested hourly in the absence...

journal_title：Behavioral neuroscience

authors： Guile MN,McCutcheon NB

更新日期：1984-08-01 00:00:00

abstract：:A microstructural analysis of the licking behavior of the rat was used to investigate the effects of total abdominal vagotomy on ingestive behavior. Vagotomy decreased the meal size of milk and 3 concentrations of sucrose. The decrease was due to an increase in the decline in the rate of licking during the meal, sugge...

journal_title：Behavioral neuroscience

authors： Davis JD,Smith GP,Kung TM

更新日期：1994-08-01 00:00:00

abstract：:Adult rats have been phenotyped as high (HRs) or low (LRs) responders to novelty, the former associated with high-risk behaviors. Data indicating that adolescent rodents exhibit increased novelty-seeking relative to adults are equivocal, and phenotypic variations in adolescent novel stimulus reactivity are unknown. To...

journal_title：Behavioral neuroscience

authors： Philpot RM,Wecker L

更新日期：2008-08-01 00:00:00

abstract：:The estradiol (E2), estrogen receptor-α (ERα), testosterone (T), and androgen receptor (AR) can contribute to anxiety, but whether they are associated with the reversion of prenatal adverse outcomes remains unclear. Here, we tested the interactive effects of prenatal maternal restraint stress and early postnatal short...

journal_title：Behavioral neuroscience

authors： He FQ,Fang G,Wang B,Guo XJ,Guo CL

更新日期：2015-12-01 00:00:00

abstract：:The neurexins are a family of presynaptic cell adhesion molecules. Human genetic studies have found heterozygous deletions affecting NRXN1 and NRXN2, encoding α-neurexin I (Nrxn1α) and α-neurexin II (Nrxn2α), in individuals with autism spectrum disorders and schizophrenia. However, the link between α-neurexin deficien...

journal_title：Behavioral neuroscience

authors： Dachtler J,Ivorra JL,Rowland TE,Lever C,Rodgers RJ,Clapcote SJ

更新日期：2015-12-01 00:00:00

abstract：:The possibility that female-paced coital behavior induces a reward state of sufficient intensity and duration to induce conditioning was evaluated by the conditioned-place-preference paradigm. Ovariectomized female rats, treated with estradiol benzoate and progesterone, regulated (paced) their coital interactions with...

journal_title：Behavioral neuroscience

authors： Paredes RG,Alonso A

更新日期：1997-02-01 00:00:00

abstract：:There is evidence that the nitric oxide (NO)/soluble guanylyl cyclase (sGC)/cGMP-dependent protein kinase (PKG) signaling pathway in the basal lateral amygdala and hippocampus plays a key role in memory processing, but it is not known if this NO signaling pathway in the nucleus accumbens (Gomes et al., 2006), a known ...

journal_title：Behavioral neuroscience

authors： Shen F,Wang N,Qi C,Li YJ,Cui CL

更新日期：2014-08-01 00:00:00

abstract：:The present experiment monitored bilateral eyelid responses during eyeblink conditioning in rats trained with a unilateral unconditioned stimulus (US). Three groups of rats were used to determine if cross-modal savings occurs when the location of the US is switched from one eye to the other. Rats in each group first r...

journal_title：Behavioral neuroscience

authors： Campolattaro MM,Buss EW,Freeman JH

更新日期：2015-12-01 00:00:00

abstract：:The defensive withdrawal reflex of the mantle organs (gill, siphon, and mantle shelf) of the marine mollusc Aplysia californica has been the subject of numerous studies investigating the cellular and molecular mechanisms of learning. In behavioral experiments, the reflex has been monitored by means of two different re...

journal_title：Behavioral neuroscience

authors： Stopfer M,Carew TJ

更新日期：1987-04-01 00:00:00

abstract：:Experimental data and computational models suggest that blockade of muscarinic cholinergic receptors impairs paired-associate learning and increases proactive interference (E. DeRosa & M. E. Hasselmo, 2000; M. E. Hasselmo & J. M. Bower, 1993). The results presented here provide evidence in humans supporting these hypo...

journal_title：Behavioral neuroscience

authors： Atri A,Sherman S,Norman KA,Kirchhoff BA,Nicolas MM,Greicius MD,Cramer SC,Breiter HC,Hasselmo ME,Stern CE

更新日期：2004-02-01 00:00:00

abstract：:Lesions of either the dorsomedial thalamus (DMT) or the parafascicular region of the thalamus (PFA) reduced rough-and-tumble social play in juvenile rats, as measured by frequency of pinning. Pinning was reduced by 33% in pups with DMT lesions and by 73% in pups with PFA lesions. Although PFA lesions had minimal effec...

journal_title：Behavioral neuroscience

authors： Siviy SM,Panksepp J

更新日期：1985-12-01 00:00:00

abstract：:This study reexamined Grigson's reward comparison hypothesis (1997), which claimed to have resolved the paradox of addictive, rewarding drugs manifesting an aversive effect in the conditioned taste aversion (CTA) paradigm. Here, the authors compared the conditioned suppression effects of lithium chloride (LiCl) and am...

journal_title：Behavioral neuroscience

authors： Huang AC,Hsiao S

更新日期：2008-12-01 00:00:00

abstract：:Effects of posttraining epinephrine (EPI) on retention of a massed (1 session, 30 trials) 2-way active avoidance task in rats were studied. The rats received an injection (ip) of 0.05 mg/kg EPI, 0.01 mg/kg EPI, or distilled water immediately after the training session. EPI did not improve retention 24 hr after the tra...

journal_title：Behavioral neuroscience

authors： Costa-Miserachs D,Portell-Cortés I,Aldavert-Vera L,Torras-García M,Morgado-Bernal I

更新日期：1994-06-01 00:00:00

abstract：:The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...

journal_title：Behavioral neuroscience

authors： Jasnow AM,Shi C,Israel JE,Davis M,Huhman KL

更新日期：2005-08-01 00:00:00

abstract：:The ability to attend to appropriate stimuli, to plan actions and then alter those actions when environmental conditions change, is essential for an organism to thrive. There is increasing evidence that these executive control processes are mediated in part by N-methyl-D-aspartate receptors (NMDAR). NMDAR subunits con...

journal_title：Behavioral neuroscience

authors： Thompson SM,Josey M,Holmes A,Brigman JL

更新日期：2015-04-01 00:00:00

abstract：:Animals with sham operations, hippocampal formation, or small and large parietal cortex lesions were trained in a task that required memory for short or long lists of items (spatial locations). More specifically, on any one trial, a rat is presented with 2, 4, 6, 8, or 10 items (spatial locations) on a 12-arm radial m...

journal_title：Behavioral neuroscience

authors： Kametani H,Kesner RP

更新日期：1989-02-01 00:00:00

abstract：:Idazoxan, an alpha 2 adrenoceptor antagonist (2 mg/kg), enhanced novel object investigation in a holeboard in rats as previously reported (V. Devauges & S. J. Sara, 1990). Two weeks of 10 min/day in 37 degrees C water increased dopamine-beta-hydroxylase staining density in the locus coeruleus but did not enhance novel...

journal_title：Behavioral neuroscience

authors： Mansour AA,Babstock DM,Penney JH,Martin GM,McLean JH,Harley CW

更新日期：2003-06-01 00:00:00

abstract：:Available evidence indicates that common genes influence alcohol and tobacco abuse in humans. The studies reported here used mouse models to evaluate the hypothesis that genetically determined variability in the alpha4beta2* nicotinic receptor modulates genetically determined variability in the intake of both nicotine...

journal_title：Behavioral neuroscience

authors： Butt CM,King NM,Hutton SR,Collins AC,Stitzel JA

更新日期：2005-02-01 00:00:00

abstract：:Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway...

journal_title：Behavioral neuroscience

authors： Reeves TM,Smith DC

更新日期：1987-04-01 00:00:00

abstract：:Chorda tympani nerve (CT) transection in rats severely impairs NaCl taste detection. These rats can detect higher concentrations of NaCl, however, suggesting that remaining oral nerves maintain some salt sensibility. Rats were tested in a gustometer with a 2-response operant taste-detection task before and after sham ...

journal_title：Behavioral neuroscience

authors： Blonde GD,Garcea M,Spector AC

更新日期：2006-06-01 00:00:00

abstract：:In infant rats, administration of the alpha2 adrenoceptor agonist clonidine simultaneously evokes ultrasound production and bradycardia. In this study the authors examined in 8-day-old rats whether these 2 responses to clonidine are causally related. In Experiment 1 pups were pretreated with saline or prenalterol (0.1...

journal_title：Behavioral neuroscience

authors： Blumberg MS,Kreber LA,Sokoloff G,Kent KJ

更新日期：2000-06-01 00:00:00

abstract：:Bilateral peripeduncular (PPN) lesions made on the seventh postpartum day (L7) with either radiofrequency (RF) current or N-methyl-d,l-aspartic acid (NMDA)/phosphate buffered saline (PBS) reduced maternal aggression (MA) and partially inhibited lactation without producing significant deficits in other items of materna...

journal_title：Behavioral neuroscience

authors： Factor EM,Mayer AD,Rosenblatt JS

更新日期：1993-02-01 00:00:00

abstract：:Male prairie voles (Microtus ochrogaster) form a pair bond with a female partner after mating, and this behavior is regulated by the neuropeptide vasopressin (AVP). The authors report that AVP in the lateral septum is important for pair bond formation. Administration of an AVP V1a receptor antagonist in the lateral se...

journal_title：Behavioral neuroscience

authors： Liu Y,Curtis JT,Wang Z

更新日期：2001-08-01 00:00:00

abstract：:In order to examine the development of tolerance to opioids, eight cynomolgus and two rhesus monkeys were trained to press a lever for food reinforcement and then were catheterized so that drugs could be infused. Three doses of hydromorphone and six different interdose intervals were studied. Hydromorphone infusions i...

journal_title：Behavioral neuroscience

authors： Ternes JW,Ehrman R,O'Brien CP

更新日期：1983-04-01 00:00:00

abstract：:In the separated arms conditioned cue preference (CCP) task rats are trained by confining them in one arm of an eight-arm radial maze with food and in another arm on the opposite side of the maze with no food on alternate days. After two such trials, rats prefer the food-paired arm when allowed to move freely between ...

journal_title：Behavioral neuroscience

authors： Naeem M,White NM

更新日期：2011-02-01 00:00:00

abstract：:Previous studies have identified a population of cells recorded in the postsubiculum and the anterior thalamic nucleus (ATN) that discharge as a function of an animal's head direction (HD) in the horizontal plane. The present experiments monitored HD cell activity when rats were confronted with a situation in which di...

journal_title：Behavioral neuroscience

authors： Goodridge JP,Taube JS

更新日期：1995-02-01 00:00:00