Cynomolgus monkeys do not develop tolerance to opioids.

abstract：:Monkeys with conjoint bilateral lesions of the hippocampus and amygdala were impaired on four different tests of memory (delayed retention of object discriminations, concurrent discrimination, delayed response, and delayed nonmatching to sample). Because tests involving delays and distractions are known to be especial...

journal_title：Behavioral neuroscience

authors： Zola-Morgan S,Squire LR

更新日期：1985-02-01 00:00:00

abstract：:Four rhesus monkeys (Macaca mulatta) were trained to learn novel sets of visuomotor associations in 50 trials or less, within single test sessions. After bilateral ablation of the orbital and ventral prefrontal cortex, the monkeys lost the ability to learn these associations within a session, although they could learn...

journal_title：Behavioral neuroscience

authors： Bussey TJ,Wise SP,Murray EA

更新日期：2001-10-01 00:00:00

abstract：:Previous findings are discordant regarding the effects of perinatal lesions of Cortical Areas 17 and 18 on visual discrimination learning in cats. Three potential determinants of such sparing were investigated: age at lesion (4 or 181 days), age at testing (3 or 9 months), and stimulus complexity. Age at testing was n...

journal_title：Behavioral neuroscience

authors： Cornwell P,Herbein S,Corso C,Eskew R,Warren JM,Payne B

更新日期：1989-12-01 00:00:00

abstract：:Studies have shown that noxious cutaneous stimulation engages physiologically different antinociceptive systems to inhibit a spinal reflex, tail withdrawal from radiant heat. Two experiments are reported that examine the relationship between the inhibition of the tail-flick response and brain-mediated responses to noc...

journal_title：Behavioral neuroscience

authors： Crown ED,Grau JW,Meagher MW

更新日期：2004-12-01 00:00:00

abstract：:Previous electrophysiological studies and computational modeling suggest the hypothesis that cholinergic neuromodulation may reduce olfactory associative interference during learning (M. E. Hasselmo, B. P. Anderson, & J. M. Bower, 1992; M. E. Hasselmo & J. M. Bower, 1993). These results provide behavioral evidence sup...

journal_title：Behavioral neuroscience

authors： De Rosa E,Hasselmo ME

更新日期：2000-02-01 00:00:00

abstract：:The shy-bold continuum is a fundamental behavioral trait conserved across human and nonhuman animals. Individual differences along the shy-bold continuum are presumed to arise from, and are maintained by, differences in the excitability of forebrain limbic areas involved in the evaluation of stimulus saliency. To test...

journal_title：Behavioral neuroscience

authors： Beaton EA,Schmidt LA,Schulkin J,Antony MM,Swinson RP,Hall GB

更新日期：2008-06-01 00:00:00

abstract：:Substantial evidence suggests that pharmacological manipulations of neural serotonin pathways influence ingestive behaviors. Despite the known role of the nucleus accumbens in directing appetitive and consummatory behavior, there has been little examination of the influences that serotonin receptors may play in modula...

journal_title：Behavioral neuroscience

authors： Pratt WE,Blackstone K,Connolly ME,Skelly MJ

更新日期：2009-10-01 00:00:00

abstract：:Six females rats were trained to lever press under a free operant shock-postponement schedule. Each subject had a yoked control which received shock whenever the subject did. The shock-postponement interval (R-S) was varied from 5, 10, 20, 40, to 80 s over blocks of sessions. Corticosteroid levels were taken prior to ...

journal_title：Behavioral neuroscience

authors： Herrmann TF,Hurwitz HM,Levine S

更新日期：1984-12-01 00:00:00

abstract：:Among young adults, 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") is a popular drug of abuse, and anecdotal evidence indicates that repeated use of MDMA may result in impairments in sexual function and decreased sex drive in human users. There has been little investigation of the effects of MDMA on sexual functi...

journal_title：Behavioral neuroscience

authors： Straiko MM,Gudelsky GA,Coolen LM

更新日期：2007-06-01 00:00:00

abstract：:Transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) from olfactory sensory neurons to the olfactory bulb as well as odor detection and discrimination were examined in rats in which each nasal epithelium had been irrigated with 0.1-0.5 ml 5% zinc sulfate. After treatment, rats showed few or no deficits ...

journal_title：Behavioral neuroscience

authors： Slotnick B,Glover P,Bodyak N

更新日期：2000-08-01 00:00:00

abstract：:The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...

journal_title：Behavioral neuroscience

authors： Jasnow AM,Shi C,Israel JE,Davis M,Huhman KL

更新日期：2005-08-01 00:00:00

abstract：:The authors have recently shown that attenuation of an external response feedback leads to excessive lever-pressing that is not associated with attempts to collect reward, and they have suggested that this may be an analogue to "unreasonable" excessive behavior characteristic of obsessive-compulsive disorder. The pres...

journal_title：Behavioral neuroscience

authors： Joel D,Avisar A,Doljansky J

更新日期：2001-12-01 00:00:00

abstract：:Modification of acoustic startle amplitude by a 10-ms tone prepulse (S1) was evaluated as a function of the interstimulus interval (ISI) between the onset of S1 and the onset of the startle-evoking stimulus (S2). Subjects were normal-hearing 1-month-old C57BL/6J (C57) mice and CBA/CaJ mice and 5-month-old C57 mice wit...

journal_title：Behavioral neuroscience

authors： Willott JF,Carlson S

更新日期：1995-06-01 00:00:00

abstract：:The rewarding properties of centrally administered ethanol (EtOH) were examined using a conditioned place preference (CPP) test. Male rats subjected to bilateral intracerebroventricular (icv) infusions of EtOH (0-240 nmol) produced a dose-dependent preference for the drug-paired environment that was potentiated by con...

journal_title：Behavioral neuroscience

authors： Walker BM,Ettenberg A

更新日期：2007-04-01 00:00:00

abstract：:The sensitivity of several inbred strains of mice was assessed for ethanol's effects on activity, body temperature, ataxia, balance, and the righting reflex. Genotypic correlations among the mean responses for the strains were estimated as indexes of pleiotropic influences of genes on drug responses. Three major group...

journal_title：Behavioral neuroscience

authors： Crabbe JC

更新日期：1983-04-01 00:00:00

abstract：:The acoustic startle response (ASR) of male rats was measured during several sessions over a 24-hr period in both a light-dark cycle and a constant-dark condition. Each session consisted of 10 trials each at 80, 90, 100, 110, and 120 dB white noise. The results indicate robust daily and circadian modulation of ASR amp...

journal_title：Behavioral neuroscience

authors： Chabot CC,Taylor DH

更新日期：1992-10-01 00:00:00

abstract：:Neuropeptide Y (NPY) is a potent endogenous stimulator of food intake. In addition to stimulating increased food intake, when paired with a novel-flavored solution, NPY produces an aversion to that flavor. Hence, exogenous NPY elicits 2 seemingly opposing behaviors, increased feeding and the formation of a conditioned...

journal_title：Behavioral neuroscience

authors： Madden LJ,Seeley RJ,Woods SC

更新日期：1999-08-01 00:00:00

abstract：:Two experiments were conducted to determine the effectiveness of strychnine sulfate in attenuating the amnesia induced in mice by small doses of cycloheximide (CYC). Previously, reversal of CYC-induced amnesia catecholamine agonists has been taken as evidence that protein synthesis inhibitors induce amnesia via an inh...

journal_title：Behavioral neuroscience

authors： Leccese AP,Quinton EE

更新日期：1983-04-01 00:00:00

abstract：:The present study examined the effects of lesions of the central nucleus of the amygdala (CeA) on the acquisition of a new response with conditioned reinforcement (CR) and its potentiation by intra-accumbens infusions of d-amphetamine (1, 3, 10, and 20 microg/microl). Rats were trained to associate a light-plus-noise ...

journal_title：Behavioral neuroscience

authors： Robledo P,Robbins TW,Everitt BJ

更新日期：1996-10-01 00:00:00

abstract：:The spontaneously hypertensive rat (SHR) has been suggested as a possible animal model of attention-deficit/hyperactivity disorder (ADHD). Reductions in the volume of the cerebellum and impairments in cerebellar-dependent eyeblink conditioning have been observed in ADHD, prompting investigation into whether SHRs also ...

journal_title：Behavioral neuroscience

authors： Chess AC,Green JT

更新日期：2008-02-01 00:00:00

abstract：:Rats received kindling stimulations to the perirhinal cortex (PRh), ventral hippocampus (VH), or dorsal hippocampus (DH) in 1 environment and an equivalent number of sham stimulations in a 2nd environment. The PRh-kindled rats displayed rapid kindling and a swift emergence of conditioned interictal defensiveness. In c...

journal_title：Behavioral neuroscience

authors： Barnes SJ,Hua JM,Pinel JP,Takahashi A,Wig GS

更新日期：2005-12-01 00:00:00

abstract：:The nature of anticipatory responding in rats with unilateral subthalamic nucleus lesions was examined. Rats were trained to respond toward visual targets that were preceded by 1 of 4 different cues. For normal rats, a cue invokes an involuntary attentional orienting that enhances processing of the target at the locat...

journal_title：Behavioral neuroscience

authors： Phillips JM,Brown VJ

更新日期：2000-02-01 00:00:00

abstract：:Whether olfactory working memory involves verbal representations or neural images of odor per se remains unclear. This study investigated whether verbal representation influences performance in an olfactory delayed-match-to-sample task and used monorhinal presentation to generate hypotheses as to the underlying anatom...

journal_title：Behavioral neuroscience

authors： Yeshurun Y,Dudai Y,Sobel N

更新日期：2008-10-01 00:00:00

abstract：:Sustained potential shifts (SPS) were recorded for 10 s from the surface of the optic tectum of toads presented with live prey and moving artificial prey stimuli. On the anterior tectal surface, a negative SPS was followed by a positive wave; the converse was true for the posterior tectum. Some animals were immobilize...

journal_title：Behavioral neuroscience

authors： Laming PR,Ocherashvili IV,Nicol AU,Roughan JV,Laming BA

更新日期：1995-02-01 00:00:00

abstract：:Animals with sham operations, hippocampal formation, or small and large parietal cortex lesions were trained in a task that required memory for short or long lists of items (spatial locations). More specifically, on any one trial, a rat is presented with 2, 4, 6, 8, or 10 items (spatial locations) on a 12-arm radial m...

journal_title：Behavioral neuroscience

authors： Kametani H,Kesner RP

更新日期：1989-02-01 00:00:00

abstract：:In male rats with food and water freely available, the specific dopamine D2 antagonist YM-09151-2 had little effect on total food or water intake across a 24-hr period. However, it produced a substantial dose-related decrease in feeding rate during meals and an enhancement of both meal size and duration. The equivalen...

journal_title：Behavioral neuroscience

authors： Clifton PG,Rusk IN,Cooper SJ

更新日期：1991-04-01 00:00:00

abstract：:Neuropsin (kallikrein-related peptidase 8) is concentrated in the hippocampus, amygdala, olfactory bulb, and prefrontal cortex. Earlier studies showed that protease deficiency causes a significant impairment of early-phase long-term potentiation in the Schaffer collateral pathway and hippocampus-dependent memory in th...

journal_title：Behavioral neuroscience

authors： Horii Y,Yamasaki N,Miyakawa T,Shiosaka S

更新日期：2008-06-01 00:00:00

abstract：:A long-held view has been that interest of male mice in female body odors reflects an activation of reward circuits in the male brain following their detection by the vomeronasal organ (VNO) and processing via the accessory olfactory system. We found that adult, sexually naive male mice acquired a conditioned place pr...

journal_title：Behavioral neuroscience

authors： Korzan WJ,Freamat M,Johnson AG,Cherry JA,Baum MJ

更新日期：2013-10-01 00:00:00

abstract：:The present study examined the effect of lesions of the caudate nucleus or fimbria-fornix on the acquisition of two water maze tasks. In both tasks, two rubber balls with different visual patterns were used as platforms (i.e., cues). The "correct" cue was attached to a submerged rectangular platform and could be mount...

journal_title：Behavioral neuroscience

authors： Packard MG,McGaugh JL

更新日期：1992-06-01 00:00:00

abstract：:To test whether habituation is specific to the stimulus modality, the authors analyzed cross-habituation between the tactile startle response' (TSR) and the acoustic startle response (ASR). The acoustic artifacts of airpuffs used to elicit the TSR were reduced by using a silencer and were effectively masked by backgro...

journal_title：Behavioral neuroscience

authors： Pilz PK,Carl TD,Plappert CF

更新日期：2004-10-01 00:00:00