Modification of the acoustic startle response in hearing-impaired C57BL/6J mice: prepulse augmentation and prolongation of prepulse inhibition.

abstract：:Estrogens have been shown to rapidly promote male copulatory behaviors with a time-course that suggests rapid signaling events are involved. The present study tested the hypothesis that estrogen acts through a novel Gq protein-coupled membrane estrogen receptor (ER). Thus, either estradiol (E2), STX (a diphenylacrylam...

journal_title：Behavioral neuroscience

authors： Kaufman KR,Kelly MJ,Roselli CE

更新日期：2013-08-01 00:00:00

abstract：:Among young adults, 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") is a popular drug of abuse, and anecdotal evidence indicates that repeated use of MDMA may result in impairments in sexual function and decreased sex drive in human users. There has been little investigation of the effects of MDMA on sexual functi...

journal_title：Behavioral neuroscience

authors： Straiko MM,Gudelsky GA,Coolen LM

更新日期：2007-06-01 00:00:00

abstract：:It is widely believed that male mammals have better spatial ability than females. A large number of evolutionary hypotheses have been proposed to explain these differences, but few species have been tested. The authors critically review the proposed evolutionary explanations for sex differences in spatial cognition an...

journal_title：Behavioral neuroscience

authors： Jones CM,Braithwaite VA,Healy SD

更新日期：2003-06-01 00:00:00

abstract：:The context preexposure facilitation effect (CPFE) is a variant of contextual fear conditioning in which context learning, context-shock association, and expression of context conditioning occur in 3 separate phases-preexposure, training, and testing. During the preexposure phase, the CPFE is disrupted by hippocampal ...

journal_title：Behavioral neuroscience

authors： Robinson-Drummer PA,Dokovna LB,Heroux NA,Stanton ME

更新日期：2016-04-01 00:00:00

abstract：:The acoustic startle response (ASR) of male rats was measured during several sessions over a 24-hr period in both a light-dark cycle and a constant-dark condition. Each session consisted of 10 trials each at 80, 90, 100, 110, and 120 dB white noise. The results indicate robust daily and circadian modulation of ASR amp...

journal_title：Behavioral neuroscience

authors： Chabot CC,Taylor DH

更新日期：1992-10-01 00:00:00

abstract：:Lateralization of the Morris water maze task was examined by injecting 5 ng of tetrodotoxin (TTX) into one dorsal hippocampus (HPC) of chronically cannulated rats (n = 20). The task, acquired (A) during unilateral HPC block, was retrieved (R) during TTX blockade of the ipsi- (I) or contralateral (C) HPC. Escape latenc...

journal_title：Behavioral neuroscience

authors： Fenton AA,Bures J

更新日期：1993-08-01 00:00:00

abstract：:Past work has demonstrated robust brain changes in cholecystokinin (CCK-8) following social defeat. Here the authors analyzed brain regional, CCK-8, substance P, corticotropin releasing factor (CRF), and neuropeptide Y levels in adult male Long-Evans rats defeated in a resident-intruder social aggression paradigm, as ...

journal_title：Behavioral neuroscience

authors： Panksepp J,Burgdorf J,Beinfeld MC,Kroes RA,Moskal JR

更新日期：2007-12-01 00:00:00

abstract：:Dopamine in the medial preoptic area (MPOA) facilitates copulation in male rats, and nitric oxide (NO) regulates basal and female-stimulated MPOA dopamine release. Microinjection of L-nitro-arginine methyl ester (L-NAME, an NO synthesis inhibitor) into the MPOA blocked copulation in naive rats and impaired copulation ...

journal_title：Behavioral neuroscience

authors： Lagoda G,Muschamp JW,Vigdorchik A,Hull EM

更新日期：2004-12-01 00:00:00

abstract：:In Pavlovian overshadowing, a stimulus that predicts a biologically important event reduces conditioning to another, equally predictive stimulus. We tested the effects of an opioid antagonist and dopamine agonist on the ability of a salient white noise to overshadow a less salient light. Rats were conditioned to fear ...

journal_title：Behavioral neuroscience

authors： Zelikowsky M,Fanselow MS

更新日期：2010-08-01 00:00:00

abstract：:To determine whether dopamine signaling in the dorsal striatum is sufficient for performance of goal-directed behaviors, local dopamine production was restored in the dorsal striatum of dopamine-deficient (DD) mice through viral-mediated gene therapy. Virally rescued DD (vrDD) mice were tested for learning of an appet...

journal_title：Behavioral neuroscience

authors： Robinson S,Sotak BN,During MJ,Palmiter RD

更新日期：2006-02-01 00:00:00

abstract：:The purpose of this study was to evaluate the sensorimotor skills of a spontaneous mouse mutant, Purkinje cell degeneration (PCD), marked by selective cerebellar cortical atrophy on a treadmill activated at 1 of 2 speeds and at 1 of 3 slopes, requiring forward movements to avoid footshocks. There was no difference in ...

journal_title：Behavioral neuroscience

authors： Le Marec N,Lalonde R

更新日期：1998-02-01 00:00:00

abstract：:Bilateral peripeduncular (PPN) lesions made on the seventh postpartum day (L7) with either radiofrequency (RF) current or N-methyl-d,l-aspartic acid (NMDA)/phosphate buffered saline (PBS) reduced maternal aggression (MA) and partially inhibited lactation without producing significant deficits in other items of materna...

journal_title：Behavioral neuroscience

authors： Factor EM,Mayer AD,Rosenblatt JS

更新日期：1993-02-01 00:00:00

abstract：:Prader-Willi syndrome (PWS) is caused by lack of paternally derived gene expression from the imprinted gene cluster on human chromosome 15q11-q13. PWS is characterized by severe hypotonia, a failure to thrive in infancy and, on emerging from infancy, evidence of learning disabilities and overeating behavior due to an ...

journal_title：Behavioral neuroscience

authors： Relkovic D,Humby T,Hagan JJ,Wilkinson LS,Isles AR

更新日期：2012-06-01 00:00:00

abstract：:Young and aged animals were tested on a spatial alternation task that consisted of two interleaved components: (1) an "outbound" or alternation component (working memory) and (2) an "inbound" component, requiring the animal to remember to return to a central location in space (spatial memory). In the present study, ag...

journal_title：Behavioral neuroscience

authors： Kapellusch AJ,Lester AW,Schwartz BA,Smith AC,Barnes CA

更新日期：2018-12-01 00:00:00

abstract：:Previous research conducted in monkeys and rats has established that the perirhinal cortex is critically involved in object- or stimulus-recognition memory, whereas other research suggests this region may contribute to memory for object discriminations. These findings do not rule out the possibility that the perirhina...

journal_title：Behavioral neuroscience

authors： Wiig KA,Burwell RD

更新日期：1998-08-01 00:00:00

abstract：:Previous studies have found that in mature animals habituation is context-specific in some species but not in others. Given the mixed evidence present in the literature, we decided to explore whether habituation is context-specific in newborn chicks. The results showed that 3 days after hatching, chicks were capable o...

journal_title：Behavioral neuroscience

authors： Chiandetti C,Turatto M

更新日期：2017-10-01 00:00:00

abstract：:Neonatal handling induces long-lasting effects on behaviors and stress responses. The objective of the present study was to analyze the effects of neonatal handling (from the 1st to the 10th day after delivery) on the number of cells and volume of locus coeruleus (LC) nucleus in male and female rats at 4 different age...

journal_title：Behavioral neuroscience

authors： Lucion AB,Pereira FM,Winkelman EC,Sanvitto GL,Anselmo-Franci JA

更新日期：2003-10-01 00:00:00

abstract：:A long-held view has been that interest of male mice in female body odors reflects an activation of reward circuits in the male brain following their detection by the vomeronasal organ (VNO) and processing via the accessory olfactory system. We found that adult, sexually naive male mice acquired a conditioned place pr...

journal_title：Behavioral neuroscience

authors： Korzan WJ,Freamat M,Johnson AG,Cherry JA,Baum MJ

更新日期：2013-10-01 00:00:00

abstract：:Hindlimb flexion induced by direct stimulation of the hindlimb has been observed subsequent to spinal section if an appropriate time interval was allowed to elapse between onset of flexion and spinal cord section. The present series of experiments was conducted to test the possibility that asymmetry persistence is a p...

journal_title：Behavioral neuroscience

authors： Steinmetz JE,Beggs AL,Lupica CR,Patterson MM

更新日期：1983-12-01 00:00:00

abstract：:The ability of the rat brain to acquire or to retain specific learning tasks was tested under conditions of multiple lesions and widely different amounts of practice. Lesion targets were (a) the medial prefrontal and cingulate cortex, (b) the anterior and mediodorsal thalamus, and (c) the dorsal and ventral hippocampu...

journal_title：Behavioral neuroscience

authors： Markowitsch HJ,Kessler J,Streicher M

更新日期：1985-04-01 00:00:00

abstract：:Chronic exposure to light at night (LAN) is a circadian disruptor and may be linked to various health risks, including mood disorders. We recently demonstrated that chronic exposure to dim (5 lux) LAN provokes depressive-like behaviors and reduced hippocampal CA1 dendritic spine density in female hamsters. Whether thi...

journal_title：Behavioral neuroscience

authors： Bedrosian TA,Weil ZM,Nelson RJ

更新日期：2012-10-01 00:00:00

abstract：:Access to a running wheel combined with restricted feeding produced body weight loss at an equivalent rate in male and female litter-mate rats (Experiment 1). Thus, despite weighing less and running more, females were not more vulnerable to this procedure. When factors influencing weight loss were varied, no sex diffe...

journal_title：Behavioral neuroscience

authors： Boakes RA,Mills KJ,Single JP

更新日期：1999-10-01 00:00:00

abstract：:Two experiments explored the role of the opioid system in a situation involving a surprising reduction in reward magnitude: consummatory successive negative contrast. Rats received access to 32% sucrose solution (preshift Trials 1-10) followed by 4% solution (postshift Trials 11-15). Independent groups received an inj...

journal_title：Behavioral neuroscience

authors： Wood M,Daniel AM,Papini MR

更新日期：2005-04-01 00:00:00

abstract：:Withdrawal from an escalating-dose, bingelike regimen of cocaine administration in rats produced significantly depressed levels of locomotor activity during the nocturnal portion of the day-night cycle. This effect was observed during the first 48 hr of testing. Extracellular single-unit recordings of ventral tegmenta...

journal_title：Behavioral neuroscience

authors： Koeltzow TE,White FJ

更新日期：2003-08-01 00:00:00

abstract：:The hippocampus is important for the acquisition of new memories. It is also one of the few regions in the adult mammalian brain that can generate new nerve cells. The authors tested the hypothesis that voluntary exercise increases neurogenesis and enhances spatial learning in mice selectively bred for high levels of ...

journal_title：Behavioral neuroscience

authors： Rhodes JS,van Praag H,Jeffrey S,Girard I,Mitchell GS,Garland T Jr,Gage FH

更新日期：2003-10-01 00:00:00

abstract：:The purpose of this experiment was to evaluate the extent to which continued drug discrimination training during chronic drug treatment affects the development of tolerance. Rats were trained to discriminate distilled water from 0.75 mg/kg amphetamine in a two-lever drug discrimination task. Two groups were then given...

journal_title：Behavioral neuroscience

authors： Caul WF,Burgin KL,Barrett RJ

更新日期：1989-04-01 00:00:00

abstract：:In Pavlovian eyeblink conditioning, the conditioned response (CR) is highly lateralized to the eye to which the unconditioned stimulus (US) has been directed. However, the initial conditioning of one eye can facilitate subsequent conditioning of the other eye, a phenomenon known as the intereye transfer (IET) effect. ...

journal_title：Behavioral neuroscience

authors： Lee T,Kim JJ,Wagner AR

更新日期：2008-12-01 00:00:00

abstract：:The effects of estrogenic stimulation on diet selection were examined in intact, estrous cycling rats, ovariectomized (OVX) rats, and OVX rats given estradiol benzoate (EB) hormone replacement therapy. In Experiment 1, OVX was associated with the nearly exclusive choice of the more calorically dense diet of a pair of ...

journal_title：Behavioral neuroscience

authors： Bartness TJ,Waldbillig RJ

更新日期：1984-02-01 00:00:00

abstract：:The amygdala is an integrator of affective processing, and a key component of a network regulating social behavior. While decades of lesion studies in nonhuman primates have shown alterations in social interactions after amygdala damage, acute manipulations of the amygdala in primates have been underexplored. We recen...

journal_title：Behavioral neuroscience

authors： Forcelli PA,Wellman LL,Malkova L

更新日期：2017-04-01 00:00:00

abstract：:Infant humans were trained on 2 cognitive tests that have previously revealed, in infant monkeys, a double dissociation that was reversible by perinatal manipulations of androgens and ablations of specific brain sites. Children showed the same sex-linked behavior found with infant monkeys: young boys were superior on ...

journal_title：Behavioral neuroscience

authors： Overman WH,Bachevalier J,Schuhmann E,Ryan P

更新日期：1996-08-01 00:00:00