Selective effects of the delta-opioid receptor agonist DPDPE on consummatory successive negative contrast.

Abstract:

:Two experiments explored the role of the opioid system in a situation involving a surprising reduction in reward magnitude: consummatory successive negative contrast. Rats received access to 32% sucrose solution (preshift Trials 1-10) followed by 4% solution (postshift Trials 11-15). Independent groups received an injection of either the vehicle or the delta-receptor agonist [D-Ala2-,N-Me-Phe4,Gly-ol] enkephalin (DPDPE; 24 microg/kg). DPDPE attenuated the contrast effect when injected before Trial 11 but not when injected before Trial 12. An additional experiment showed that the attenuating effect of partial reinforcement on the recovery from contrast was reduced by DPDPE injections administered before nonreinforced preshift trials.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Wood M,Daniel AM,Papini MR

doi

10.1037/0735-7044.119.2.446

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

446-54

issue

2

eissn

0735-7044

issn

1939-0084

pii

2005-03585-008

journal_volume

119

pub_type

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