Abstract:
:The acoustic startle reflex (ASR) is potentiated during negative emotion, but attenuated during positive emotional experience. The modulation of the ASR by fear depends critically on the amygdala. The authors investigated ASR modulation to fearful, disgusting, pleasant, and neutral stimuli in 12 patients with unilateral damage to the anteromedial temporal lobe including the amygdala (6 left, 6 right), 1 patient with bilateral temporal lobe damage including the amygdala, and 12 comparison participants. Both groups with unilateral damage, as well as the subject with bilateral damage, showed a complete lack of ASR potentiation to both fear and disgust stimuli. The findings suggest that potentiation of the ASR by disgust and fear depends on the integrity of the anteromedial temporal lobe.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Buchanan TW,Tranel D,Adolphs Rdoi
10.1037/0735-7044.118.2.429subject
Has Abstractpub_date
2004-04-01 00:00:00pages
429-37issue
2eissn
0735-7044issn
1939-0084pii
2004-12681-020journal_volume
118pub_type
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journal_title:Behavioral neuroscience
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pub_type: 杂志文章
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
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