Abstract:
:The aim of this study was to investigate the effects of postnatal choline supplementation on neurochemical and behavioral parameters in preweanling BALB/cByJ mice. Mouse pups were injected daily subcutaneously with choline chloride (0.85 mM/g body weight) from Postnatal Day (PND) 1 to PND 16. Pups performed a passive avoidance (PA) learning task on PND 17-18 and a 30-min locomotor activity test on PND 19. The choline treatment affected retention of the PA task on PND 18. The treatment also increased locomotor activity in females, but not in males, on PND 19. Choline acetyltransferase (ChAT) enzymatic activity was measured on PND 20 and revealed that choline administration in the first 2 weeks of postnatal life selectively affects male pups. Choline's effect, as seen in previous rat experiments, was to decrease ChAT activity in the hippocampal region.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Ricceri L,Berger-Sweeney Jsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
1387-92issue
6eissn
0735-7044issn
1939-0084journal_volume
112pub_type
杂志文章abstract::Fetal and maternal data were monitored serially at 6 gestational ages from 20 to 38 weeks in 195 Peruvian fetuses. Digitized data included fetal heart rate and motor activity, as well as maternal heart rate and electrodermal conductance. Time series analysis evaluated the development of synchrony in 2 streams of fetal...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.120.3.687
更新日期:2006-06-01 00:00:00
abstract::Rats were injected with naloxone hydrochloride (3 mg/kg) or saline and subjected to preshock or no preshock prior to receiving a test shock that elicited defensive burying. Preshock was administered in a context different from, or the same as, that in which the test shock was delivered. The combination of naloxone and...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.99.3.436
更新日期:1985-06-01 00:00:00
abstract::Technological advances over the last decade are changing the face of behavioral neuroscience research. Here we review recent work on the use of one such transformative tool in behavioral neuroscience research, chemogenetics (or Designer Receptors Exclusively Activated by Designer Drugs, DREADDS). As transformative tec...
journal_title:Behavioral neuroscience
pub_type: 杂志文章,评审
doi:10.1037/bne0000135
更新日期:2016-04-01 00:00:00
abstract::Following spinal transection of the upper thoracic spinal cord, male Sprague-Dawley rats given legshock whenever a hindlimb is extended learn to maintain the leg in a flexed position. The region of the cord that mediates this instrumental learning was isolated using neuroanatomical tracing, localized infusion of lidoc...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.119.2.538
更新日期:2005-04-01 00:00:00
abstract::The antinociceptive effects of signaled shock and its physiological underpinnings were examined in two experiments. In Experiment 1, rats were exposed to one of three shock conditions: no shock, unsignaled shock, and signaled (by a 10-s, 1000-Hz tone) shock. In each condition the rats were tested hourly in the absence...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.98.4.695
更新日期:1984-08-01 00:00:00
abstract::The C. elegans mutants, lrn-1 and lrn-2, are impaired in associative learning using conditioned taste cues. Both mutants are defective in associative learning about appetitive and aversive events, indicating that lrn-1 and lrn-2 exert effects across motivational boundaries. In a new olfactory associative learning para...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.113.2.358
更新日期:1999-04-01 00:00:00
abstract::The present experiment monitored bilateral eyelid responses during eyeblink conditioning in rats trained with a unilateral unconditioned stimulus (US). Three groups of rats were used to determine if cross-modal savings occurs when the location of the US is switched from one eye to the other. Rats in each group first r...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000105
更新日期:2015-12-01 00:00:00
abstract::Measurement of cerebrospinal concentrations of oxytocin (OT) in intact and peridural-anesthetized ewes showed that central release of OT during parturition is inhibited by this anesthesia. Also, observations of maternal behavior and attraction to amniotic fluid (AF) in inexperienced peridural-anesthetized parturient e...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.106.2.427
更新日期:1992-04-01 00:00:00
abstract::Contradictory results are found in the literature concerning the role of vision in the perception of space or in spatial navigation, in part because of the lack of murine models of total blindness used so far. The authors evaluated the spatial abilities of anophthalmic transgenic mice. These mice did not differ qualit...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::Circadian rhythms in most mammals are synchronized to local time by phase and period resetting actions of daily light-dark cycles on a retino-recipient, light-entrainable circadian pacemaker, the suprachiasmatic nucleus (SCN). The SCN receives input from other brain regions, some of which mediate the phase and period ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章,评审
doi:10.1037/a0035885
更新日期:2014-06-01 00:00:00
abstract::Novelty seeking refers to the tendency of humans and animals to explore novel and unfamiliar stimuli and environments. The idea that dopamine modulates novelty seeking is supported by evidence that novel stimuli excite dopamine neurons and activate brain regions receiving dopaminergic input. In addition, dopamine is s...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0037128
更新日期:2014-10-01 00:00:00
abstract::Regulation of energy intake depends in part on both memory for prior food intake and internal signals of hunger and satiety. These functions are both mediated by the hippocampus, a brain structure that animal studies have shown to be impaired after maintenance on high fat and refined sugar (HFS) diets. Study 1, using ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0025998
更新日期:2011-12-01 00:00:00
abstract::Two groups of rats were trained on operant discriminations in which the discriminanda were two different sound pressure levels of a 4-kHz tone. The discriminanda were chosen so that the loudness difference between stimuli was equivalent for each group when calculated from a power function with an exponent of .35. Half...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.97.3.392
更新日期:1983-06-01 00:00:00
abstract::This study was prompted by reports of functionally normal humans with micrencephaly or cortical hypoplasia. Methylazoxymethanol acetate (MAM) treatment, which induces micrencephaly in rats, was administered by injection (20 mg/kg) on gestational day 14. Prior to weaning and into adulthood, offspring were assessed on m...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.6.1067
更新日期:1993-12-01 00:00:00
abstract::These experiments examined the sufficiency of pairing an odor with either intrabulbar activation of noradrenergic beta-receptors or pharmacological stimulation of the locus coeruleus to support learned odor preferences in Postnatal Day 6-7 rat pups. The results showed that pups exposed to odor paired with beta-recepto...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.114.5.957
更新日期:2000-10-01 00:00:00
abstract::Aggressive tendencies may be linked to the psychopharmacology of cocaine, yet few experimental approaches have been brought to bear on understanding the neurobiological implications of cocaine exposure during the developmentally sensitive period of adolescence. In this issue, Melloni and coauthors (L. A. Ricci, J. M. ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章,评审
doi:10.1037/0735-7044.118.5.1143
更新日期:2004-10-01 00:00:00
abstract::The female steroid hormone 17beta-estradiol enhances synaptic transmission and the magnitude of longterm potentiation (LTP) in adult rodent hippocampal slices. Long-term depression (LTD), another form of synaptic plasticity, occurs more prominently in hippocampal slices from aged rodents. A decrease in LTP has been re...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.122.2.301
更新日期:2008-04-01 00:00:00
abstract::Fear conditioning shows associations formed between contextual or auditory stimuli with an unconditioned stimulus. Inbred mouse strains differ in their ability to demonstrate fear conditioning, suggesting at least a partial genetic influence. The present study identified the possible chromosomal loci regulating fear c...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.2.292
更新日期:1997-04-01 00:00:00
abstract::Conditioned inhibition (CI) of the rat eyeblink response and the neuronal correlates of CI in the cerebellar interpositus nucleus were examined in the present study. In Experiment 1, CI was established with a novel, 3-group design. In Experiment 2, neuronal activity in the anterior interpositus nucleus was recorded du...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract::Studies have shown that ovarian hormones protect against some of the cognitive deficits associated with aging. Although much of the literature in rodents has focused on hippocampal dependent tasks, studies suggest that tasks dependent on the prefrontal cortex are also influenced by ovarian hormones. The present study ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0026461
更新日期:2012-02-01 00:00:00
abstract::A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract:INTRODUCTION:Caffeine is frequently consumed concurrent to or immediately following ethanol consumption. Identifying how caffeine and ethanol interact to modulate behavior is essential to understanding the co-use of these drugs. The plus-maze discriminative avoidance task (PMDAT) allows within-subject measurement of le...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0017610
更新日期:2009-12-01 00:00:00
abstract::Galanin is a 29-amino-acid neuropeptide that is overexpressed in Alzheimer's disease (AD) and impairs performance on rodent learning and memory tasks. M40, a peptidergic galanin receptor ligand, blocks galanin-induced impairments on delayed non-matching-to-position (DNMTP). The present experiments used the 192IgG-sapo...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.3.552
更新日期:1997-06-01 00:00:00
abstract::The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.5.877
更新日期:2007-10-01 00:00:00
abstract::Two experiments were conducted to determine the effectiveness of strychnine sulfate in attenuating the amnesia induced in mice by small doses of cycloheximide (CYC). Previously, reversal of CYC-induced amnesia catecholamine agonists has been taken as evidence that protein synthesis inhibitors induce amnesia via an inh...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.97.2.323
更新日期:1983-04-01 00:00:00
abstract::Studies have shown that noxious cutaneous stimulation engages physiologically different antinociceptive systems to inhibit a spinal reflex, tail withdrawal from radiant heat. Two experiments are reported that examine the relationship between the inhibition of the tail-flick response and brain-mediated responses to noc...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.6.1418
更新日期:2004-12-01 00:00:00
abstract::To examine the role of the medial zona incerta (mZI) in female sexual behavior, ovariectomized estrogen- and progesterone-treated female rats were tested for sexual receptivity after bilateral injections of the selective neurotoxin ibotenic acid (3 micrograms/0.3 microliter) directly into the mZI. These injections pro...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.1.210
更新日期:1991-02-01 00:00:00
abstract::The hippocampus is important for the acquisition of new memories. It is also one of the few regions in the adult mammalian brain that can generate new nerve cells. The authors tested the hypothesis that voluntary exercise increases neurogenesis and enhances spatial learning in mice selectively bred for high levels of ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.117.5.1006
更新日期:2003-10-01 00:00:00
abstract::Rats with unilateral dopamine (DA) depletion (hemiParkinson analogue rats) are impaired in using the contralateral (bad) limbs for skilled movements and for postural adjustments and compensate by using their good limbs in novel ways. The present study consisted of a reaching task in which compensatory adjustments usin...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.1.117
更新日期:1996-02-01 00:00:00
abstract::Fifty-eight 4-day-old male rats were studied. Peripheral desensitization was induced in 36 rats by sc administration of capsaicin in increasing doses (350, 700, 1,400, 2,100, and 2,800 micrograms) on 5 consecutive days. When adult, 9 treated and 5 control rats were chronically implanted with a lateral intracerebrovent...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.97.5.822
更新日期:1983-10-01 00:00:00