Postnatal choline supplementation in preweanling mice: sexually dimorphic behavioral and neurochemical effects.

Abstract:

:The aim of this study was to investigate the effects of postnatal choline supplementation on neurochemical and behavioral parameters in preweanling BALB/cByJ mice. Mouse pups were injected daily subcutaneously with choline chloride (0.85 mM/g body weight) from Postnatal Day (PND) 1 to PND 16. Pups performed a passive avoidance (PA) learning task on PND 17-18 and a 30-min locomotor activity test on PND 19. The choline treatment affected retention of the PA task on PND 18. The treatment also increased locomotor activity in females, but not in males, on PND 19. Choline acetyltransferase (ChAT) enzymatic activity was measured on PND 20 and revealed that choline administration in the first 2 weeks of postnatal life selectively affects male pups. Choline's effect, as seen in previous rat experiments, was to decrease ChAT activity in the hippocampal region.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Ricceri L,Berger-Sweeney J

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

1387-92

issue

6

eissn

0735-7044

issn

1939-0084

journal_volume

112

pub_type

杂志文章
  • Prenatal development of intrafetal and maternal-fetal synchrony.

    abstract::Fetal and maternal data were monitored serially at 6 gestational ages from 20 to 38 weeks in 195 Peruvian fetuses. Digitized data included fetal heart rate and motor activity, as well as maternal heart rate and electrodermal conductance. Time series analysis evaluated the development of synchrony in 2 streams of fetal...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.120.3.687

    authors: DiPietro JA,Caulfield LE,Irizarry RA,Chen P,Merialdi M,Zavaleta N

    更新日期:2006-06-01 00:00:00

  • Naloxone, preshock, and defensive burying.

    abstract::Rats were injected with naloxone hydrochloride (3 mg/kg) or saline and subjected to preshock or no preshock prior to receiving a test shock that elicited defensive burying. Preshock was administered in a context different from, or the same as, that in which the test shock was delivered. The combination of naloxone and...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.99.3.436

    authors: Whiteside DA,Devenport LD

    更新日期:1985-06-01 00:00:00

  • DREADDS: Use and application in behavioral neuroscience.

    abstract::Technological advances over the last decade are changing the face of behavioral neuroscience research. Here we review recent work on the use of one such transformative tool in behavioral neuroscience research, chemogenetics (or Designer Receptors Exclusively Activated by Designer Drugs, DREADDS). As transformative tec...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/bne0000135

    authors: Smith KS,Bucci DJ,Luikart BW,Mahler SV

    更新日期:2016-04-01 00:00:00

  • Instrumental learning within the rat spinal cord: localization of the essential neural circuit.

    abstract::Following spinal transection of the upper thoracic spinal cord, male Sprague-Dawley rats given legshock whenever a hindlimb is extended learn to maintain the leg in a flexed position. The region of the cord that mediates this instrumental learning was isolated using neuroanatomical tracing, localized infusion of lidoc...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.119.2.538

    authors: Liu GT,Ferguson AR,Crown ED,Bopp AC,Miranda RC,Grau JW

    更新日期:2005-04-01 00:00:00

  • Effects of naltrexone and signaling inescapable electric shock on nociception and gastric lesions in rats.

    abstract::The antinociceptive effects of signaled shock and its physiological underpinnings were examined in two experiments. In Experiment 1, rats were exposed to one of three shock conditions: no shock, unsignaled shock, and signaled (by a 10-s, 1000-Hz tone) shock. In each condition the rats were tested hourly in the absence...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.98.4.695

    authors: Guile MN,McCutcheon NB

    更新日期:1984-08-01 00:00:00

  • Olfactory associative learning in Caenorhabditis elegans is impaired in lrn-1 and lrn-2 mutants.

    abstract::The C. elegans mutants, lrn-1 and lrn-2, are impaired in associative learning using conditioned taste cues. Both mutants are defective in associative learning about appetitive and aversive events, indicating that lrn-1 and lrn-2 exert effects across motivational boundaries. In a new olfactory associative learning para...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.113.2.358

    authors: Morrison GE,Wen JY,Runciman S,van der Kooy D

    更新日期:1999-04-01 00:00:00

  • Cross-modal savings in the contralateral eyelid conditioned response.

    abstract::The present experiment monitored bilateral eyelid responses during eyeblink conditioning in rats trained with a unilateral unconditioned stimulus (US). Three groups of rats were used to determine if cross-modal savings occurs when the location of the US is switched from one eye to the other. Rats in each group first r...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000105

    authors: Campolattaro MM,Buss EW,Freeman JH

    更新日期:2015-12-01 00:00:00

  • Intracerebral oxytocin is important for the onset of maternal behavior in inexperienced ewes delivered under peridural anesthesia.

    abstract::Measurement of cerebrospinal concentrations of oxytocin (OT) in intact and peridural-anesthetized ewes showed that central release of OT during parturition is inhibited by this anesthesia. Also, observations of maternal behavior and attraction to amniotic fluid (AF) in inexperienced peridural-anesthetized parturient e...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.106.2.427

    authors: Lévy F,Kendrick KM,Keverne EB,Piketty V,Poindron P

    更新日期:1992-04-01 00:00:00

  • Exploration, anxiety, and spatial memory in transgenic anophthalmic mice.

    abstract::Contradictory results are found in the literature concerning the role of vision in the perception of space or in spatial navigation, in part because of the lack of murine models of total blindness used so far. The authors evaluated the spatial abilities of anophthalmic transgenic mice. These mice did not differ qualit...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Buhot MC,Dubayle D,Malleret G,Javerzat S,Segu L

    更新日期:2001-04-01 00:00:00

  • Regulation of circadian rhythms in mammals by behavioral arousal.

    abstract::Circadian rhythms in most mammals are synchronized to local time by phase and period resetting actions of daily light-dark cycles on a retino-recipient, light-entrainable circadian pacemaker, the suprachiasmatic nucleus (SCN). The SCN receives input from other brain regions, some of which mediate the phase and period ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/a0035885

    authors: Webb IC,Antle MC,Mistlberger RE

    更新日期:2014-06-01 00:00:00

  • Dopamine modulates novelty seeking behavior during decision making.

    abstract::Novelty seeking refers to the tendency of humans and animals to explore novel and unfamiliar stimuli and environments. The idea that dopamine modulates novelty seeking is supported by evidence that novel stimuli excite dopamine neurons and activate brain regions receiving dopaminergic input. In addition, dopamine is s...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0037128

    authors: Costa VD,Tran VL,Turchi J,Averbeck BB

    更新日期:2014-10-01 00:00:00

  • Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals.

    abstract::Regulation of energy intake depends in part on both memory for prior food intake and internal signals of hunger and satiety. These functions are both mediated by the hippocampus, a brain structure that animal studies have shown to be impaired after maintenance on high fat and refined sugar (HFS) diets. Study 1, using ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0025998

    authors: Francis HM,Stevenson RJ

    更新日期:2011-12-01 00:00:00

  • Loudness scaling and masking in rats.

    abstract::Two groups of rats were trained on operant discriminations in which the discriminanda were two different sound pressure levels of a 4-kHz tone. The discriminanda were chosen so that the loudness difference between stimuli was equivalent for each group when calculated from a power function with an exponent of .35. Half...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.97.3.392

    authors: Raslear TG,Pierrel-Sorrentino R,Rudnick F

    更新日期:1983-06-01 00:00:00

  • Behavioral effects of methylazoxymethanol-induced micrencephaly.

    abstract::This study was prompted by reports of functionally normal humans with micrencephaly or cortical hypoplasia. Methylazoxymethanol acetate (MAM) treatment, which induces micrencephaly in rats, was administered by injection (20 mg/kg) on gestational day 14. Prior to weaning and into adulthood, offspring were assessed on m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.107.6.1067

    authors: Ferguson SA,Racey FD,Paule MG,Holson RR

    更新日期:1993-12-01 00:00:00

  • Association of an odor with activation of olfactory bulb noradrenergic beta-receptors or locus coeruleus stimulation is sufficient to produce learned approach responses to that odor in neonatal rats.

    abstract::These experiments examined the sufficiency of pairing an odor with either intrabulbar activation of noradrenergic beta-receptors or pharmacological stimulation of the locus coeruleus to support learned odor preferences in Postnatal Day 6-7 rat pups. The results showed that pups exposed to odor paired with beta-recepto...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.114.5.957

    authors: Sullivan RM,Stackenwalt G,Nasr F,Lemon C,Wilson DA

    更新日期:2000-10-01 00:00:00

  • Aggression upon adolescent cocaine exposure linked to serotonin anomalies: theoretical comment on Ricci et al. (2004).

    abstract::Aggressive tendencies may be linked to the psychopharmacology of cocaine, yet few experimental approaches have been brought to bear on understanding the neurobiological implications of cocaine exposure during the developmentally sensitive period of adolescence. In this issue, Melloni and coauthors (L. A. Ricci, J. M. ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/0735-7044.118.5.1143

    authors: Cunningham KA

    更新日期:2004-10-01 00:00:00

  • 17beta-estradiol modifies stress-induced and age-related changes in hippocampal synaptic plasticity.

    abstract::The female steroid hormone 17beta-estradiol enhances synaptic transmission and the magnitude of longterm potentiation (LTP) in adult rodent hippocampal slices. Long-term depression (LTD), another form of synaptic plasticity, occurs more prominently in hippocampal slices from aged rodents. A decrease in LTP has been re...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.122.2.301

    authors: Foy MR,Baudry M,Foy JG,Thompson RF

    更新日期:2008-04-01 00:00:00

  • Identification of quantitative trait loci involved in contextual and auditory-cued fear conditioning in BXD recombinant inbred strains.

    abstract::Fear conditioning shows associations formed between contextual or auditory stimuli with an unconditioned stimulus. Inbred mouse strains differ in their ability to demonstrate fear conditioning, suggesting at least a partial genetic influence. The present study identified the possible chromosomal loci regulating fear c...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.2.292

    authors: Owen EH,Christensen SC,Paylor R,Wehner JM

    更新日期:1997-04-01 00:00:00

  • Neuronal correlates of conditioned inhibition of the eyeblink response in the anterior interpositus nucleus.

    abstract::Conditioned inhibition (CI) of the rat eyeblink response and the neuronal correlates of CI in the cerebellar interpositus nucleus were examined in the present study. In Experiment 1, CI was established with a novel, 3-group design. In Experiment 2, neuronal activity in the anterior interpositus nucleus was recorded du...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Nicholson DA,Freeman JH Jr

    更新日期:2002-02-01 00:00:00

  • Long-term replacement of estrogen in combination with medroxyprogesterone acetate improves acquisition of an alternation task in middle-aged female rats.

    abstract::Studies have shown that ovarian hormones protect against some of the cognitive deficits associated with aging. Although much of the literature in rodents has focused on hippocampal dependent tasks, studies suggest that tasks dependent on the prefrontal cortex are also influenced by ovarian hormones. The present study ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0026461

    authors: Chisholm NC,Juraska JM

    更新日期:2012-02-01 00:00:00

  • Dissociation of conditioned locomotion and Fos induction in response to stimuli formerly paired with cocaine.

    abstract::A discrete stimulus (flashing light) was paired with cocaine (20 mg/kg) to induce conditioned locomotion. To identify brain regions activated during this response, Fos was measured with immunohistochemistry. Although paired subjects displayed robust conditioned locomotion, Fos was not increased in any limbic brain reg...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Hotsenpiller G,Horak BT,Wolf ME

    更新日期:2002-08-01 00:00:00

  • Effects of ethanol and caffeine on behavior in C57BL/6 mice in the plus-maze discriminative avoidance task.

    abstract:INTRODUCTION:Caffeine is frequently consumed concurrent to or immediately following ethanol consumption. Identifying how caffeine and ethanol interact to modulate behavior is essential to understanding the co-use of these drugs. The plus-maze discriminative avoidance task (PMDAT) allows within-subject measurement of le...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0017610

    authors: Gulick D,Gould TJ

    更新日期:2009-12-01 00:00:00

  • Analysis of galanin and the galanin antagonist M40 on delayed non-matching-to-position performance in rats lesioned with the cholinergic immunotoxin 192 IgG-saporin.

    abstract::Galanin is a 29-amino-acid neuropeptide that is overexpressed in Alzheimer's disease (AD) and impairs performance on rodent learning and memory tasks. M40, a peptidergic galanin receptor ligand, blocks galanin-induced impairments on delayed non-matching-to-position (DNMTP). The present experiments used the 192IgG-sapo...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.3.552

    authors: McDonald MP,Wenk GL,Crawley JN

    更新日期:1997-06-01 00:00:00

  • Food reinforcement, the dopamine D2 receptor genotype, and energy intake in obese and nonobese humans.

    abstract::The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.121.5.877

    authors: Epstein LH,Temple JL,Neaderhiser BJ,Salis RJ,Erbe RW,Leddy JJ

    更新日期:2007-10-01 00:00:00

  • Attenuation of cycloheximide-induced amnesia in mice with strychnine sulfate.

    abstract::Two experiments were conducted to determine the effectiveness of strychnine sulfate in attenuating the amnesia induced in mice by small doses of cycloheximide (CYC). Previously, reversal of CYC-induced amnesia catecholamine agonists has been taken as evidence that protein synthesis inhibitors induce amnesia via an inh...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.97.2.323

    authors: Leccese AP,Quinton EE

    更新日期:1983-04-01 00:00:00

  • Pain in a balance: noxious events engage opposing processes that concurrently modulate nociceptive reactivity.

    abstract::Studies have shown that noxious cutaneous stimulation engages physiologically different antinociceptive systems to inhibit a spinal reflex, tail withdrawal from radiant heat. Two experiments are reported that examine the relationship between the inhibition of the tail-flick response and brain-mediated responses to noc...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.118.6.1418

    authors: Crown ED,Grau JW,Meagher MW

    更新日期:2004-12-01 00:00:00

  • Ibotenic acid-induced lesions of the medial zona incerta decrease lordosis behavior in the female rat.

    abstract::To examine the role of the medial zona incerta (mZI) in female sexual behavior, ovariectomized estrogen- and progesterone-treated female rats were tested for sexual receptivity after bilateral injections of the selective neurotoxin ibotenic acid (3 micrograms/0.3 microliter) directly into the mZI. These injections pro...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.105.1.210

    authors: Dornan WA,Peterson M,Matuszewich L,Malen P

    更新日期:1991-02-01 00:00:00

  • Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running.

    abstract::The hippocampus is important for the acquisition of new memories. It is also one of the few regions in the adult mammalian brain that can generate new nerve cells. The authors tested the hypothesis that voluntary exercise increases neurogenesis and enhances spatial learning in mice selectively bred for high levels of ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.117.5.1006

    authors: Rhodes JS,van Praag H,Jeffrey S,Girard I,Mitchell GS,Garland T Jr,Gage FH

    更新日期:2003-10-01 00:00:00

  • HemiParkinson analogue rats display active support in good limbs versus passive support in bad limbs on a skilled reaching task of variable height.

    abstract::Rats with unilateral dopamine (DA) depletion (hemiParkinson analogue rats) are impaired in using the contralateral (bad) limbs for skilled movements and for postural adjustments and compensate by using their good limbs in novel ways. The present study consisted of a reaching task in which compensatory adjustments usin...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.1.117

    authors: Miklyaeva EI,Whishaw IQ

    更新日期:1996-02-01 00:00:00

  • Dissociation between peripheral and central heat loss mechanisms induced by neonatal capsaicin.

    abstract::Fifty-eight 4-day-old male rats were studied. Peripheral desensitization was induced in 36 rats by sc administration of capsaicin in increasing doses (350, 700, 1,400, 2,100, and 2,800 micrograms) on 5 consecutive days. When adult, 9 treated and 5 control rats were chronically implanted with a lateral intracerebrovent...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.97.5.822

    authors: Dib B

    更新日期:1983-10-01 00:00:00