Postnatal choline supplementation in preweanling mice: sexually dimorphic behavioral and neurochemical effects.

Abstract:

:The aim of this study was to investigate the effects of postnatal choline supplementation on neurochemical and behavioral parameters in preweanling BALB/cByJ mice. Mouse pups were injected daily subcutaneously with choline chloride (0.85 mM/g body weight) from Postnatal Day (PND) 1 to PND 16. Pups performed a passive avoidance (PA) learning task on PND 17-18 and a 30-min locomotor activity test on PND 19. The choline treatment affected retention of the PA task on PND 18. The treatment also increased locomotor activity in females, but not in males, on PND 19. Choline acetyltransferase (ChAT) enzymatic activity was measured on PND 20 and revealed that choline administration in the first 2 weeks of postnatal life selectively affects male pups. Choline's effect, as seen in previous rat experiments, was to decrease ChAT activity in the hippocampal region.

journal_name

Behav Neurosci

journal_title

Behavioral neuroscience

authors

Ricceri L,Berger-Sweeney J

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

1387-92

issue

6

eissn

0735-7044

issn

1939-0084

journal_volume

112

pub_type

杂志文章
  • Cardiac startle and orienting responses in the great apes.

    abstract::Cardiac patterns of startle and orienting in response to auditory and vibrotactile stimuli were investigated in the infant chimpanzee and gorilla. Results revealed a notable cardiac acceleration in response to the initial presentations of stimuli of either modality. This acceleratory response appeared to reflect the c...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.98.5.914

    authors: Berntson GG,Boysen ST

    更新日期:1984-10-01 00:00:00

  • Species differences in the vasopressin-immunoreactive pathways in the bed nucleus of the stria terminalis and medial amygdaloid nucleus in prairie voles (Microtus ochrogaster) and meadow voles (Microtus pennsylvanicus).

    abstract::Vasopressin-immunoreactive (AVP-ir) cells in the bed nucleus of the stria terminalis (BST) and medial amygdaloid nucleus (MA) and their AVP-ir projections to the lateral septum were studied in monogamous prairie voles (Microtus ochrogaster) and promiscuous meadow voles (M. pennsylvanicus). A sexually dimorphic AVP-ir ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.109.2.305

    authors: Wang Z

    更新日期:1995-04-01 00:00:00

  • Working memory across nostrils.

    abstract::Whether olfactory working memory involves verbal representations or neural images of odor per se remains unclear. This study investigated whether verbal representation influences performance in an olfactory delayed-match-to-sample task and used monorhinal presentation to generate hypotheses as to the underlying anatom...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0012806

    authors: Yeshurun Y,Dudai Y,Sobel N

    更新日期:2008-10-01 00:00:00

  • Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose-response study in humans.

    abstract::The effects of various doses (40 microg/kg/hr, 300 microg/kg/hr, 600 microg/kg/hr or placebo) of hydrocortisone on tasks assessing working and declarative memory function were measured in 4 groups of 10 young men. During the infusion, participants were given an item-recognition working memory task, a paired-associate ...

    journal_title:Behavioral neuroscience

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1037//0735-7044.113.3.420

    authors: Lupien SJ,Gillin CJ,Hauger RL

    更新日期:1999-06-01 00:00:00

  • Regulation of circadian rhythms in mammals by behavioral arousal.

    abstract::Circadian rhythms in most mammals are synchronized to local time by phase and period resetting actions of daily light-dark cycles on a retino-recipient, light-entrainable circadian pacemaker, the suprachiasmatic nucleus (SCN). The SCN receives input from other brain regions, some of which mediate the phase and period ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章,评审

    doi:10.1037/a0035885

    authors: Webb IC,Antle MC,Mistlberger RE

    更新日期:2014-06-01 00:00:00

  • HemiParkinson analogue rats display active support in good limbs versus passive support in bad limbs on a skilled reaching task of variable height.

    abstract::Rats with unilateral dopamine (DA) depletion (hemiParkinson analogue rats) are impaired in using the contralateral (bad) limbs for skilled movements and for postural adjustments and compensate by using their good limbs in novel ways. The present study consisted of a reaching task in which compensatory adjustments usin...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.1.117

    authors: Miklyaeva EI,Whishaw IQ

    更新日期:1996-02-01 00:00:00

  • Cynomolgus monkeys do not develop tolerance to opioids.

    abstract::In order to examine the development of tolerance to opioids, eight cynomolgus and two rhesus monkeys were trained to press a lever for food reinforcement and then were catheterized so that drugs could be infused. Three doses of hydromorphone and six different interdose intervals were studied. Hydromorphone infusions i...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.97.2.327

    authors: Ternes JW,Ehrman R,O'Brien CP

    更新日期:1983-04-01 00:00:00

  • The relation of feeding and activity following septal lesions in rats.

    abstract::The patterns of intake of liquid diet and water were recorded in diet-deprived rats with septal lesions and neurologically intact controls during the first hour of diet access. The occurrences of grooming, resting/sleeping, and exploring were also recorded. Both groups of rats consumed similar amounts of diet in one m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.100.3.416

    authors: Flynn FW,Evey LA,Steele TL,Mitchell JC

    更新日期:1986-06-01 00:00:00

  • Parallel augmentation of hippocampal long-term potentiation, theta rhythm, and contextual fear conditioning in water-deprived rats.

    abstract::The influence of water deprivation on hippocampal long-term potentiation (LTP), theta rhythm, and contextual fear conditioning in rats was examined. In Experiment 1, hippocampal EEG activity and perforant path LTP were assessed in pentobarbital-anesthetized rats. Water deprivation did not affect baseline cell excitabi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.108.1.44

    authors: Maren S,DeCola JP,Swain RA,Fanselow MS,Thompson RF

    更新日期:1994-02-01 00:00:00

  • Anterior rhinal cortex and amygdala: dissociation of their contributions to memory and food preference in rhesus monkeys.

    abstract::Rhesus monkeys were trained on 2 versions of delayed nonmatching-to-sample, one with multiple pairs of objects and the other with a single pair, to evaluate their ability to remember objects. They then received either bilateral aspiration lesions of the anterior rhinal cortex or bilateral excitotoxic lesions of the am...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:

    authors: Murray EA,Gaffan EA,Flint RW Jr

    更新日期:1996-02-01 00:00:00

  • Fixation of spinal reflex alterations in spinal rats by sensory nerve stimulation.

    abstract::Two preparations in which sensory nerve stimulation was used to obtain peripherally induced spinal fixation in spinal rats are described. In the first preparation, proportionally greater amounts of persisting poststimulation flexor muscle contraction, as measured by a force displacement transducer, were produced as st...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/h0092460

    authors: Steinmetz JE,Patterson MM

    更新日期:1985-02-01 00:00:00

  • Delayed development of place navigation compared to directional responding in young rats.

    abstract::Recent work from our laboratory demonstrates that both young and adult rats show a preference for directional responding over place navigation in the Morris water task. Based on these findings, previous studies on the postnatal development of spatial learning have most likely assessed the ontogeny of directional respo...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0014594

    authors: Akers KG,Candelaria-Cook FT,Rice JP,Johnson TE,Hamilton DA

    更新日期:2009-04-01 00:00:00

  • Conditioned place preference for mating is preserved in rats with pelvic nerve transection.

    abstract::Female rats exhibit a conditioned place preference (CPP) for a context paired with mating. The present experiment tested the hypothesis that the activation of the pelvic nerve mediates the reinforcing effects of mating for female rats. Rats underwent bilateral pelvic nerve or sham transection and then received paced m...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0015267

    authors: Meerts SH,Clark AS

    更新日期:2009-06-01 00:00:00

  • Anteromedial temporal lobe damage blocks startle modulation by fear and disgust.

    abstract::The acoustic startle reflex (ASR) is potentiated during negative emotion, but attenuated during positive emotional experience. The modulation of the ASR by fear depends critically on the amygdala. The authors investigated ASR modulation to fearful, disgusting, pleasant, and neutral stimuli in 12 patients with unilater...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.118.2.429

    authors: Buchanan TW,Tranel D,Adolphs R

    更新日期:2004-04-01 00:00:00

  • Amygdala central nucleus lesions attenuate acoustic startle stimulus-evoked heart rate changes in rats.

    abstract::Amygdala central nucleus (CNA) lesions were used to test the hypothesis that stimulus-evoked heart rate changes can reflect the development of fear during acoustic startle testing. A 120-dB white noise startle stimulus produced freezing as well as phasic heart rate accelerations and decelerations, and an abrupt decrea...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.110.2.228

    authors: Young BJ,Leaton RN

    更新日期:1996-04-01 00:00:00

  • Sexual reinforcement is blocked by infusion of naloxone into the medial preoptic area.

    abstract::The present experiment was designed to determine whether infusions of naloxone into specific brain sites can block sexual reinforcement as evaluated with the conditioned place preference procedure. Methylnaloxonium (5 micrograms/cannula) was infused bilaterally either into the medial preoptic area (MPOA) or into the n...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.107.5.812

    authors: Agmo A,Gómez M

    更新日期:1993-10-01 00:00:00

  • The role of the medial prefrontal cortex in the play fighting of rats.

    abstract::Although decorticated rats are able to engage in play, their play is abnormal in three ways. First, decorticates do not display the normal, age-related shifts in defensive strategies during development. Second, decorticates do not modify their defensive tactics in response to the social identity of their partners. Thi...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0017617

    authors: Bell HC,McCaffrey DR,Forgie ML,Kolb B,Pellis SM

    更新日期:2009-12-01 00:00:00

  • Facilitation of fear extinction by midbrain periaqueductal gray infusions of RB101(S), an inhibitor of enkephalin-degrading enzymes.

    abstract::Mu-opioid receptors in the ventrolateral quadrant midbrain periaqueductal gray (vIPAG) contribute to extinction of conditioned fear. The present experiment studied whether fear extinction could be facilitated by infusions of a peptidase inhibitor that reduces catabolism of vIPAG enkephalins. Rats were trained to fear ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.119.6.1672

    authors: McNally GP

    更新日期:2005-12-01 00:00:00

  • Amygdalo-striatal interaction in the enhancement of stimulus salience in associative learning.

    abstract::Function of the central nucleus of the amygdala (CeA) is critical to 2 aspects of attention in associative learning: the conditioning of orienting responses (ORs) to cues paired with food, and the enhancement of cue salience by the surprising omission of expected events. Such salience enhancements have been found to d...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000041

    authors: Esber GR,Torres-Tristani K,Holland PC

    更新日期:2015-04-01 00:00:00

  • Thyroxine treatment reduces the anorectic effect of estradiol in rats.

    abstract::In order to examine a possible interaction between thyroxine and estradiol in the control of feeding, 14 ovariectomized adult female rats were given daily injections of 9.8 micrograms/100 g of body weight of 1-thyroxine (T). Another 14 rats received 0.15 ml of saline (S) subcutaneously each day, and food intake was me...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.100.2.284

    authors: Young JK

    更新日期:1986-04-01 00:00:00

  • Stimulation of 5-HT2A receptors recovers sensory responsiveness in acute spinal neonatal rats.

    abstract::Quipazine is a 5-HT2A-receptor agonist that has been used to induce motor activity and promote recovery of function after spinal cord injury in neonatal and adult rodents. Sensory stimulation also activates sensory and motor circuits and promotes recovery after spinal cord injury. In rats, tail pinching is an effectiv...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000176

    authors: Swann HE,Kauer SD,Allmond JT,Brumley MR

    更新日期:2017-02-01 00:00:00

  • Effects of hydrocortisone on false memory recognition in healthy men and women.

    abstract::Most of the studies focusing on the effect of stress on false memories by using psychosocial and physiological stressors yielded diverse results. In the present study, we systematically tested the effect of exogenous hydrocortisone using a false memory paradigm. In this placebo-controlled study, 37 healthy men and 38 ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000170

    authors: Duesenberg M,Weber J,Schaeuffele C,Fleischer J,Hellmann-Regen J,Roepke S,Moritz S,Otte C,Wingenfeld K

    更新日期:2016-12-01 00:00:00

  • Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.

    abstract::The neurexins are a family of presynaptic cell adhesion molecules. Human genetic studies have found heterozygous deletions affecting NRXN1 and NRXN2, encoding α-neurexin I (Nrxn1α) and α-neurexin II (Nrxn2α), in individuals with autism spectrum disorders and schizophrenia. However, the link between α-neurexin deficien...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000108

    authors: Dachtler J,Ivorra JL,Rowland TE,Lever C,Rodgers RJ,Clapcote SJ

    更新日期:2015-12-01 00:00:00

  • Reinnervation of the dentate gyrus and recovery of alternation behavior following entorhinal cortex lesions.

    abstract::Adult male rats were implanted with chronically indwelling recording electrodes in the dentate hilus of one hemisphere and bipolar stimulating electrodes in the contralateral entorhinal cortex (EC). Daily measurements were then made of the amplitude of responses, evoked through the crossed temporodentate (CTD) pathway...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.101.2.179

    authors: Reeves TM,Smith DC

    更新日期:1987-04-01 00:00:00

  • Milk-induced, opioid-mediated antinociception in rats at the time of cesarean delivery.

    abstract::Four experiments were conducted in rats within 2 hr of cesarean delivery to assess antinociception at birth and its possible opioid bases. Morphine antinociception was established in a dose-dependent fashion (0.0625-5.0 mg/kg bw). Analgesia was naloxone (1.0 mg/kg) reversible. In succeeding experiments, antinociceptio...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/0735-7044.105.5.667

    authors: Blass EM,Jackson AM,Smotherman WP

    更新日期:1991-10-01 00:00:00

  • An accessory sex gland aggression-promoting chemosignal in male mice.

    abstract::The present study investigated male murine accessory sex glands as potential sources of a urinary aggression-promoting chemosignal. Experiments 1-4 were designed to determine whether the removal of the following glands would eliminate voided urine chemosignal activity: vesicular and coagulating glands, Cowper's gland,...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.100.5.777

    authors: Ingersoll DW,Morley KT,Benvenga M,Hands C

    更新日期:1986-10-01 00:00:00

  • Effect of variation of the composition of CSF in the rat upon drinking of water and hypertonic NaCl solutions.

    abstract::Infusing conscious unrestrained rats with either 0.5 M NaCl-CSF or 0.7 M sucrose-CSF into the lateral cerebral ventricle (IVT) at 38 microliters/hr for 4 hr induced drinking. Although the infusates were nearly equiosmotic, water drinking during the 0.5 M NaCl-CSF was greater than during 0.7 M sucrose-CSF. However, IVT...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.101.3.371

    authors: Osborne PG,Denton DA,Weisinger RS

    更新日期:1987-06-01 00:00:00

  • The development of a conditioned place preference to morphine: effects of lesions of various CNS sites.

    abstract::This study examined the neural substrates underlying the development of a conditioned place preference (CPP) to morphine (2 mg/kg x 3 pairings) by testing whether lesions of 7 different neural sites block a morphine-induced CPP. Lesions of the pedunculopontine tegmental nucleus (PPTg), the periaqueductal gray (PAG), o...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037//0735-7044.111.6.1313

    authors: Olmstead MC,Franklin KB

    更新日期:1997-12-01 00:00:00

  • Parametric investigation of social place preference in adolescent mice.

    abstract::Social interaction promotes survival by helping animals to form stable and supportive groups. Additionally, maladaptive social behavior is a hallmark of disorders such as autism and schizophrenia. In many different animal species, including humans, social interaction can be inherently rewarding. Lately there has been ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/bne0000406

    authors: Cann C,Venniro M,Hope BT,Ramsey LA

    更新日期:2020-10-01 00:00:00

  • Effects of the val(158)met catechol-O-methyltransferase gene polymorphism on olfactory processing in schizophrenia.

    abstract::The catechol-O-methyltransferase (COMT) val158met polymorphism has received attention in schizophrenia due to its role in prefrontal dopamine catabolism. Given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influ...

    journal_title:Behavioral neuroscience

    pub_type: 杂志文章

    doi:10.1037/a0026466

    authors: Kamath V,Moberg PJ,Gur RE,Doty RL,Turetsky BI

    更新日期:2012-02-01 00:00:00