Abstract:
:The aim of this study was to investigate the effects of postnatal choline supplementation on neurochemical and behavioral parameters in preweanling BALB/cByJ mice. Mouse pups were injected daily subcutaneously with choline chloride (0.85 mM/g body weight) from Postnatal Day (PND) 1 to PND 16. Pups performed a passive avoidance (PA) learning task on PND 17-18 and a 30-min locomotor activity test on PND 19. The choline treatment affected retention of the PA task on PND 18. The treatment also increased locomotor activity in females, but not in males, on PND 19. Choline acetyltransferase (ChAT) enzymatic activity was measured on PND 20 and revealed that choline administration in the first 2 weeks of postnatal life selectively affects male pups. Choline's effect, as seen in previous rat experiments, was to decrease ChAT activity in the hippocampal region.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Ricceri L,Berger-Sweeney Jsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
1387-92issue
6eissn
0735-7044issn
1939-0084journal_volume
112pub_type
杂志文章abstract::Ovariectomized female rats treated with estradiol benzoate (EB) and progesterone (P) were infused intracerebroventricularly with a low (200 ng) or high (1 microgram) dose of oxytocin (OT). The low dose of OT facilitated lordosis behavior only during the dark phase of the light-dark cycle in females that were pretreate...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.3.487
更新日期:1991-06-01 00:00:00
abstract::Previous results from our laboratory have demonstrated that 3-day-old rats given dopamine (DA)-depleting brain lesions are spared the severe behavioral dysfunctions seen after comparable brain damage in adults. This behavioral sparing is accompanied by a sprouting of serotonin (5-HT)-containing neurons in the striatum...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.6.806
更新日期:1987-12-01 00:00:00
abstract::Endogenous opioids mediate some reward processes involving both natural (food, sweet taste) and artificial (morphine, heroin) rewards. In contrast, sexual behavior (which is also reinforcing) is generally inhibited by opioids. To establish the role of endogenous opioids for a newly described natural reinforcer, namely...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.122.2.416
更新日期:2008-04-01 00:00:00
abstract::The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.119.4.1125
更新日期:2005-08-01 00:00:00
abstract::Previous research shows that prenatal binge ethanol exposure during gestation days (GD) 17 to 20 of the rat, increases postnatal ethanol intake and enhances ethanol's palatability, both effects being mediated by the opioid system. The amniotic fluid of the last period of gestation (GD 20) of the rat has been found to ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0019482
更新日期:2010-06-01 00:00:00
abstract::Personality is known to influence cognitive and affective functioning as well as the risk of psychiatric disorders. Exploration of the neurobiological correlates of personality traits has the potential to enhance understanding of their significance in development of related psychopathological states. The authors exami...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.121.4.643
更新日期:2007-08-01 00:00:00
abstract::Contradictory results are found in the literature concerning the role of vision in the perception of space or in spatial navigation, in part because of the lack of murine models of total blindness used so far. The authors evaluated the spatial abilities of anophthalmic transgenic mice. These mice did not differ qualit...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::Previous studies on drug abuse have shown that response to drug-associated cues exist during prolonged abstinence. In succession to previous investigations in our laboratory on morphine dependence and our research on acquisition and expression phases of morphine-conditioned place preference (CPP), in this study we att...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000336
更新日期:2019-12-01 00:00:00
abstract::Recent work from our laboratory demonstrates that both young and adult rats show a preference for directional responding over place navigation in the Morris water task. Based on these findings, previous studies on the postnatal development of spatial learning have most likely assessed the ontogeny of directional respo...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0014594
更新日期:2009-04-01 00:00:00
abstract::The influence of 4-hydroxyamphetamine (4-OHAM) on food and water intake and in vivo brown adipose thermogenesis was examined in two experiments. In Experiment 1, female rats were treated with 0.00, 0.25, 0.50, 1.00, or 2.00 mg/kg 4-OHAM (ip) prior to assessment of interscapular brown adipose tissue (IBAT) thermogenesi...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.98.6.1060
更新日期:1984-12-01 00:00:00
abstract::Mild traumatic brain injuries are known to cause a host of symptoms, including headaches, nausea, and depression, that when persistent, are known as postconcussive syndrome. In addition to these overt symptomologies, individuals may experience changes in day-to-day behavior or temperament, which although not meeting c...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000413
更新日期:2020-10-01 00:00:00
abstract::In different experiments, pairings of a drug (pentobarbital or morphine) or place as the conditioned stimulus (CS) with lithium-induced sickness as the unconditioned stimulus (US) were given to rats to produce Pavlovian conditioning. Control rats received unpaired exposures. In the test, each rat was exposed to the CS...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.106.1.106
更新日期:1992-02-01 00:00:00
abstract::Rats treated chronically with the dopamine agonist quinpirole (0.5 mg/kg, twice weekly x 10) met 5 criteria for performance of compulsive checking. Specifically, in a large open-field with single small objects in 4 of 25 locales, quinpirole rats revisited two places/objects excessively often and rapidly, compared with...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.112.6.1475
更新日期:1998-12-01 00:00:00
abstract::Only the function relating the required pulse frequency to the interburst interval discriminates between the priming effect and the rewarding effect: Separating two short bursts of pulses has no effect on their combined rewarding effect, but it enhances their priming effect. There are significant nonscalar differences...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.105.6.884
更新日期:1991-12-01 00:00:00
abstract::Lurcher mutant (+/Lc) mice exhibit a massive loss of neurons in the cerebellar cortex and in the inferior olivary nucleus while deep cerebellar nuclei are essentially intact. To discriminate the respective participation of the cerebellar cortex and deep structures in learning and memory, the authors subjected 3- to 6-...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.1.214
更新日期:1997-02-01 00:00:00
abstract::Plasma corticosterone levels were evaluated during operant conditioning in order to determine the effect of reinforced and nonreinforced responding (extinction) on adrenal activation. The influence of instrumental responding was assessed by comparing trained rats with yoked subjects that received a matched reward sche...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.97.4.654
更新日期:1983-08-01 00:00:00
abstract::Infusing conscious unrestrained rats with either 0.5 M NaCl-CSF or 0.7 M sucrose-CSF into the lateral cerebral ventricle (IVT) at 38 microliters/hr for 4 hr induced drinking. Although the infusates were nearly equiosmotic, water drinking during the 0.5 M NaCl-CSF was greater than during 0.7 M sucrose-CSF. However, IVT...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.101.3.371
更新日期:1987-06-01 00:00:00
abstract::Rats emit aversive taste reactivity (TR) behavior (i.e., gapes) following intraoral delivery of a cocaine-paired taste cue and greater conditioned aversive TR at the end of training predicts greater drug-seeking and taking. Here, we examined the development of this conditioned aversive TR behavior on a trial-by-trial ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0036264
更新日期:2014-04-01 00:00:00
abstract::Using Hermissenda as subjects, massed-trials training deficits were examined. Associative pairings of light and rotation induced a progressively greater conditioned foot contraction in response to light as the intertrial interval (ITI) was extended (up to 8 min). In contrast, a short ITI (30 s) produced no evidence of...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.113.1.103
更新日期:1999-02-01 00:00:00
abstract::Trace eyeblink classical conditioning was assessed in patients with bilateral medial-temporal amnesia and matched control participants who had previously shown equivalent delay eyeblink conditioning (J. D. E. Gabrieli et al., 1995). The silent trace interval varied for durations of 500, 750, or 1,000 ms in successive ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.111.5.873
更新日期:1997-10-01 00:00:00
abstract::Bilateral ibotenic acid lesions of the lateral, but not the medial, parabrachial nucleus (PBN) blocked conditioned taste aversion (CTA) induced by morphine but not conditioned place preference induced by morphine. The same lateral PBN lesions also blocked conditioned place aversion produced by low intraperitoneal dose...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.1.147
更新日期:1993-02-01 00:00:00
abstract::The relative influence of morphine microinjected into the periaqueductal gray, ventral medulla (nucleus raphé magnus or nucleus reticularis gigantocellularis), or spinal subarachnoid space on the thresholds of responses organized at spinal (spinal motor reflexes, SMRs), medullary (vocalizations elicited during shock, ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.109.3.502
更新日期:1995-06-01 00:00:00
abstract::Neural correlates of associative memory and "forgetting" were observed 1, 6, and 14 days after acquisition of a conditioned response (CR) in the marine snail Hermissenda. Behavioral expression of a light-rotation association, as indexed by contraction of the animal's foot in response to light, dissipated throughout th...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.106.6.954
更新日期:1992-12-01 00:00:00
abstract::Active sleep (AS), as measured by the occurrence of myoclonic twitching (MT), is the most prevalent behavioral state in newborn rats. Historically, AS has been considered a developmental precursor of REM sleep, but recently this idea has been questioned. In the present study, the authors assess, in 2-, 5-, and 8-day-o...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.116.5.912
更新日期:2002-10-01 00:00:00
abstract::Social interaction may elicit aggression, establish social rank, and be influenced by changes in central dopaminergic activity. In the lizard Anolis carolinensis, a sign stimulus (darkening of postorbital skin or eyespots) inhibits aggressive response from opponents, in part because it forms more rapidly in dominant m...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.120.1.93
更新日期:2006-02-01 00:00:00
abstract::The amygdala is an integrator of affective processing, and a key component of a network regulating social behavior. While decades of lesion studies in nonhuman primates have shown alterations in social interactions after amygdala damage, acute manipulations of the amygdala in primates have been underexplored. We recen...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000187
更新日期:2017-04-01 00:00:00
abstract::Previous research emphasized the impact of traumatic brain injury on cholinergic systems and associated cognitive functions. Here we addressed the converse question: Because of the available evidence indicating cognitive and neuronal vulnerabilities in humans expressing low-capacity cholinergic systems or with declini...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/bne0000310
更新日期:2019-08-01 00:00:00
abstract::The striatum is implicated in response selection and performance, the dorsal striatum in sensorimotor control and habit learning, and the ventral striatum in motivation and rewarded behaviors. Ventral striatal lesions produce performance changes on food-reinforced, progressive-ratio (PR) schedules, but the effects of ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.113.4.718
更新日期:1999-08-01 00:00:00
abstract::This study examines the effects of positive and negative feedback on performance during choice reaction time tasks to assess whether they differentially affect phasic arousal and tonic activation. Participants (N = 96) received either no feedback or signals of reward, punishment, or both during a semantic and a visuos...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.116.3.397
更新日期:2002-06-01 00:00:00
abstract::The present study examined the effects of lesions of the central nucleus of the amygdala (CeA) on the acquisition of a new response with conditioned reinforcement (CR) and its potentiation by intra-accumbens infusions of d-amphetamine (1, 3, 10, and 20 microg/microl). Rats were trained to associate a light-plus-noise ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.5.981
更新日期:1996-10-01 00:00:00