Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD).

abstract：:Idazoxan, an alpha 2 adrenoceptor antagonist (2 mg/kg), enhanced novel object investigation in a holeboard in rats as previously reported (V. Devauges & S. J. Sara, 1990). Two weeks of 10 min/day in 37 degrees C water increased dopamine-beta-hydroxylase staining density in the locus coeruleus but did not enhance novel...

journal_title：Behavioral neuroscience

authors： Mansour AA,Babstock DM,Penney JH,Martin GM,McLean JH,Harley CW

更新日期：2003-06-01 00:00:00

abstract：:p-Chlorophenylalanine (pCPA) caused an increase in looping and locomotion speed in planaria (Dugesia dorotocephala). These effects dissipated quickly after treatment, except in animals that regenerated from worms surgically sectioned after treatment. Planaria that regenerated from head sections showed more looping 6 a...

journal_title：Behavioral neuroscience

authors： Kimmel HD,Carlyon WD

更新日期：1990-02-01 00:00:00

abstract：:The advent of the selective cholinergic toxin, 192 IgG-saporin, dramatically shaped subsequent research on the role of the basal forebrain in learning and memory. In particular, several articles (including the authors' 1995 Behavioral Neuroscience paper; M. G. Baxter, D. J. Bucci, L. K., Gorman, R. G. Wiley, & M. Gall...

journal_title：Behavioral neuroscience

authors： Baxter MG,Bucci DJ

更新日期：2013-10-01 00:00:00

abstract：:Although mnemonic interpretations of hippocampal function in people have been readily accepted for many years, similar interpretations of hippocampal function in animals have received a number of challenges. This article reviews two of these challenges, shows how they were resolved in favor of some kind of mnemonic in...

journal_title：Behavioral neuroscience

authors： Olton DS,Wible CG,Shapiro ML

更新日期：1986-12-01 00:00:00

abstract：:Behavioral changes induced by inescapable shock were examined in six strains of mice. Exposure to shock provoked time-dependent disturbances of shuttle escape performance. In some strains the shock treatment did not affect escape performance, whereas in others profound performance deficits were evident. The inescapabl...

journal_title：Behavioral neuroscience

authors： Shanks N,Anisman H

更新日期：1988-12-01 00:00:00

abstract：:The context preexposure facilitation effect (CPFE) is a variant of contextual fear conditioning in which context learning, context-shock association, and expression of context conditioning occur in 3 separate phases-preexposure, training, and testing. During the preexposure phase, the CPFE is disrupted by hippocampal ...

journal_title：Behavioral neuroscience

authors： Robinson-Drummer PA,Dokovna LB,Heroux NA,Stanton ME

更新日期：2016-04-01 00:00:00

abstract：:Preadolescent mice have been shown to be differentially susceptible to the effects of both acute and chronic nicotine exposure on contextual fear learning relative to adults. For this study, we tested the effects of chronic nicotine exposure in preadolescence on adulthood extinction and spontaneous recovery of fear me...

journal_title：Behavioral neuroscience

authors： Zeid D,Gould TJ

更新日期：2018-08-01 00:00:00

abstract：:Two experiments examined the effects of infusing an N-methyl-D-aspartate (NMDA) receptor antagonist, d-2-amino-5-phosphonovalerate(d-APV), on taste-potentiated odor conditioning: a form of learning that is dependent on information processing in 2 sensory modalities. In Experiment 1, rats infused with d-APV were impair...

journal_title：Behavioral neuroscience

authors： Hatfield T,Gallagher M

更新日期：1995-08-01 00:00:00

abstract：:Rats with bilateral, electrolytic lesions of perirhinal cortex (PRC), lateral entorhinal cortex (LEC), or combined lesions (PRLE) were impaired relative to controls (sham) during initial acquisition in the Morris water maze, although all groups were eventually able to learn to locate the platform. A further deficit in...

journal_title：Behavioral neuroscience

authors： Liu P,Bilkey DK

更新日期：1998-04-01 00:00:00

abstract：:Working memory depends on communication between the hippocampus and the prefrontal cortex (PFC); however, the neural circuitry that mediates interactions between these brain areas has not been well characterized. Two candidate structures are the thalamic reuniens (RE) and rhomboid (Rh) nuclei, which are reciprocally c...

journal_title：Behavioral neuroscience

authors： Hallock HL,Wang A,Shaw CL,Griffin AL

更新日期：2013-12-01 00:00:00

abstract：:The rewarding properties of centrally administered ethanol (EtOH) were examined using a conditioned place preference (CPP) test. Male rats subjected to bilateral intracerebroventricular (icv) infusions of EtOH (0-240 nmol) produced a dose-dependent preference for the drug-paired environment that was potentiated by con...

journal_title：Behavioral neuroscience

authors： Walker BM,Ettenberg A

更新日期：2007-04-01 00:00:00

abstract：:This experiment investigated the development of caching behavior and the hippocampus (HF) in postfledging mountain chickadees (Poecile gambeli). From Days 35 to 53, the number of seeds stored increased but the proportion recovered did not. Birds that stored and recovered during 3 or more trials had significantly enlar...

journal_title：Behavioral neuroscience

authors： Clayton NS

更新日期：2001-06-01 00:00:00

abstract：:Rats received kindling stimulations to the perirhinal cortex (PRh), ventral hippocampus (VH), or dorsal hippocampus (DH) in 1 environment and an equivalent number of sham stimulations in a 2nd environment. The PRh-kindled rats displayed rapid kindling and a swift emergence of conditioned interictal defensiveness. In c...

journal_title：Behavioral neuroscience

authors： Barnes SJ,Hua JM,Pinel JP,Takahashi A,Wig GS

更新日期：2005-12-01 00:00:00

abstract：:Acetylcholine (ACh) and noradrenaline (NA) release in the olfactory bulb (OB) of ewes was monitored using microdialysis. Both ACh and NA release increased at parturition in multiparous but not in primiparous ewes. However, vaginocervical stimulation performed 6 hr postpartum induced an increase of ACh and NA release i...

journal_title：Behavioral neuroscience

authors： Lévy F,Guevara-Guzman R,Hinton MR,Kendrick KM,Keverne EB

更新日期：1993-08-01 00:00:00

abstract：:Trace eyeblink classical conditioning was assessed in patients with bilateral medial-temporal amnesia and matched control participants who had previously shown equivalent delay eyeblink conditioning (J. D. E. Gabrieli et al., 1995). The silent trace interval varied for durations of 500, 750, or 1,000 ms in successive ...

journal_title：Behavioral neuroscience

authors： McGlinchey-Berroth R,Carrillo MC,Gabrieli JD,Brawn CM,Disterhoft JF

更新日期：1997-10-01 00:00:00

abstract：:This review focuses on research on both the neural substrate of maternal responsiveness and on the physiological, behavioral, and motivational adaptations to the maternal state. The female's response to her young is presented as a model motivational system and the mechanisms and neural circuitry through which the medi...

journal_title：Behavioral neuroscience

authors： Numan M,Woodside B

更新日期：2010-12-01 00:00:00

abstract：:Rats emit aversive taste reactivity (TR) behavior (i.e., gapes) following intraoral delivery of a cocaine-paired taste cue and greater conditioned aversive TR at the end of training predicts greater drug-seeking and taking. Here, we examined the development of this conditioned aversive TR behavior on a trial-by-trial ...

journal_title：Behavioral neuroscience

authors： Colechio EM,Imperio CG,Grigson PS

更新日期：2014-04-01 00:00:00

abstract：:Infusing conscious unrestrained rats with either 0.5 M NaCl-CSF or 0.7 M sucrose-CSF into the lateral cerebral ventricle (IVT) at 38 microliters/hr for 4 hr induced drinking. Although the infusates were nearly equiosmotic, water drinking during the 0.5 M NaCl-CSF was greater than during 0.7 M sucrose-CSF. However, IVT...

journal_title：Behavioral neuroscience

authors： Osborne PG,Denton DA,Weisinger RS

更新日期：1987-06-01 00:00:00

abstract：:The medial preoptic area (mPOA) is a key site for the dopaminergic enhancement of male sexual behavior. Dopamine release increases in the rat mPOA with mating, supporting the critical stimulatory role played by preoptic dopamine on male sexual behavior. However, it has been questioned whether dopamine is specifically ...

journal_title：Behavioral neuroscience

authors： Kleitz-Nelson HK,Dominguez JM,Cornil CA,Ball GF

更新日期：2010-04-01 00:00:00

abstract：:Alert wakefulness (W) and rapid eye movement sleep (REM) are remarkably similar on several measures of brain activity, but 2 differences in REM are reduced sensory responsiveness and atonia in postural muscles. Pontine tegmental lesions create REM without atonia (REM-A), releasing motor behavior. In 9 cats, we studied...

journal_title：Behavioral neuroscience

authors： Morrison AR,Sanford LD,Ball WA,Mann GL,Ross RJ

更新日期：1995-10-01 00:00:00

abstract：:In Pavlovian overshadowing, a stimulus that predicts a biologically important event reduces conditioning to another, equally predictive stimulus. We tested the effects of an opioid antagonist and dopamine agonist on the ability of a salient white noise to overshadow a less salient light. Rats were conditioned to fear ...

journal_title：Behavioral neuroscience

authors： Zelikowsky M,Fanselow MS

更新日期：2010-08-01 00:00:00

abstract：:Finicky feeding refers to an animal's tendency to become more particular in accepting and choosing food as satiation is approached. We tested the hypothesis that finickiness in the blowfly is related to the balance between internal inhibition, generated by a full crop, and external sensory information, generated by or...

journal_title：Behavioral neuroscience

authors： Moss CF,Dethier VG

更新日期：1983-08-01 00:00:00

abstract：:In humans, congenital deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a disorder known as the Lesch-Nyhan syndrome. Patients with this disorder exhibit a prominent neurobehavioral phenotype that results in part from dysfunction of catecholaminergic systems in the striatum. HPR...

journal_title：Behavioral neuroscience

authors： Jinnah HA,Gage FH,Friedmann T

更新日期：1991-12-01 00:00:00

abstract：:Neuropsin (kallikrein-related peptidase 8) is concentrated in the hippocampus, amygdala, olfactory bulb, and prefrontal cortex. Earlier studies showed that protease deficiency causes a significant impairment of early-phase long-term potentiation in the Schaffer collateral pathway and hippocampus-dependent memory in th...

journal_title：Behavioral neuroscience

authors： Horii Y,Yamasaki N,Miyakawa T,Shiosaka S

更新日期：2008-06-01 00:00:00

abstract：:The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...

journal_title：Behavioral neuroscience

authors： Epstein LH,Temple JL,Neaderhiser BJ,Salis RJ,Erbe RW,Leddy JJ

更新日期：2007-10-01 00:00:00

abstract：:Down-regulation of negative emotions has been shown to reliably inhibit the emotion-modulated startle reflex, but it remains unclear whether the timing of the startle probe influences the quantification of emotion regulation with this measure. Moreover, it is not known whether the degree of startle inhibition correspo...

journal_title：Behavioral neuroscience

authors： Zaehringer J,Schmahl C,Ende G,Paret C

更新日期：2018-12-01 00:00:00

abstract：:Previous research emphasized the impact of traumatic brain injury on cholinergic systems and associated cognitive functions. Here we addressed the converse question: Because of the available evidence indicating cognitive and neuronal vulnerabilities in humans expressing low-capacity cholinergic systems or with declini...

journal_title：Behavioral neuroscience

authors： Koshy Cherian A,Tronson NC,Parikh V,Kucinski A,Blakely RD,Sarter M

更新日期：2019-08-01 00:00:00

abstract：:Previous research (Grau, 1987a, 1987b) suggests that forebrain systems play an essential role in the hypoalgesia observed after brief shock but not long shock. Additional research has shown that pentobarbital anesthesia and decerebration block the hypoalgesia observed after 3 brief (0.75-s) shocks but not the hypoalge...

journal_title：Behavioral neuroscience

authors： Meagher MW,Grau JW,King RA

更新日期：1989-12-01 00:00:00

abstract：:In these experiments we tested the hypothesis that the respiratory events underlying rat pup ultrasonic vocalization (USV) facilitate brown adipose tissue (BAT) thermogenesis, as proposed by Blumberg and Alberts (1990). Laryngeal denervation or tracheostomy were used to reduce or eliminate laryngeal braking and preven...

journal_title：Behavioral neuroscience

authors： Hofer MA,Shair HN

更新日期：1993-04-01 00:00:00

abstract：:Chronic exposure to light at night (LAN) is a circadian disruptor and may be linked to various health risks, including mood disorders. We recently demonstrated that chronic exposure to dim (5 lux) LAN provokes depressive-like behaviors and reduced hippocampal CA1 dendritic spine density in female hamsters. Whether thi...

journal_title：Behavioral neuroscience

authors： Bedrosian TA,Weil ZM,Nelson RJ

更新日期：2012-10-01 00:00:00