Novel objects in a holeboard probe the role of the locus coeruleus in curiosity: support for two modes of attention in the rat.

abstract：:The cAMP-responsive element binding protein (CREB) is a transcription factor that regulates synaptic plasticity and memory formation. Studies that have used conditioned fear models have established that CREB is important for the acquisition and consolidation of fear learning. The authors demonstrate that overexpressio...

journal_title：Behavioral neuroscience

authors： Jasnow AM,Shi C,Israel JE,Davis M,Huhman KL

更新日期：2005-08-01 00:00:00

abstract：:The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout traini...

journal_title：Behavioral neuroscience

authors： Nicholson DA,Freeman JH Jr

更新日期：2002-04-01 00:00:00

abstract：:Six females rats were trained to lever press under a free operant shock-postponement schedule. Each subject had a yoked control which received shock whenever the subject did. The shock-postponement interval (R-S) was varied from 5, 10, 20, 40, to 80 s over blocks of sessions. Corticosteroid levels were taken prior to ...

journal_title：Behavioral neuroscience

authors： Herrmann TF,Hurwitz HM,Levine S

更新日期：1984-12-01 00:00:00

abstract：:Previous studies have demonstrated that corticopetal cholinergic lesions applied to the nucleus basalis magnocellularis and substantia innominata (NBM/SI) attenuate operant suppression induced by aversive events. However, these lesions have no effect on open-arm behavior in the elevated plus-maze or changes in startle...

journal_title：Behavioral neuroscience

authors： Knox D,Brothers H,Norman GJ,Berntson GG

更新日期：2008-06-01 00:00:00

abstract：:This study uses an operant, behavioral model to assess the daily changes in the decay rate of short-term memory, motivation, and motor ability in rats exposed to chronic restraint. Restraint decreased reward-related motivation by 50% without altering memory decay rate or motor ability. Moreover, chronic restraint impa...

journal_title：Behavioral neuroscience

authors： Kleen JK,Sitomer MT,Killeen PR,Conrad CD

更新日期：2006-08-01 00:00:00

abstract：:A microstructural analysis of the licking behavior of the rat was used to investigate the effects of total abdominal vagotomy on ingestive behavior. Vagotomy decreased the meal size of milk and 3 concentrations of sucrose. The decrease was due to an increase in the decline in the rate of licking during the meal, sugge...

journal_title：Behavioral neuroscience

authors： Davis JD,Smith GP,Kung TM

更新日期：1994-08-01 00:00:00

abstract：:The purpose of this experiment was to evaluate the extent to which continued drug discrimination training during chronic drug treatment affects the development of tolerance. Rats were trained to discriminate distilled water from 0.75 mg/kg amphetamine in a two-lever drug discrimination task. Two groups were then given...

journal_title：Behavioral neuroscience

authors： Caul WF,Burgin KL,Barrett RJ

更新日期：1989-04-01 00:00:00

abstract：:Feeding-related gustatory, olfactory, and visual activation of the orbitofrontal cortex (OFC) decreases following satiety. Previous neurophysiological studies have concentrated on the caudolateral OFC (clOFC). We describe satiety-induced modulation of 23 gustatory, 5 water, and 15 control neurons in the medial OFC (mO...

journal_title：Behavioral neuroscience

authors： Pritchard TC,Nedderman EN,Edwards EM,Petticoffer AC,Schwartz GJ,Scott TR

更新日期：2008-02-01 00:00:00

abstract：:The spontaneously hypertensive rat (SHR) has been suggested as a possible animal model of attention-deficit/hyperactivity disorder (ADHD). Reductions in the volume of the cerebellum and impairments in cerebellar-dependent eyeblink conditioning have been observed in ADHD, prompting investigation into whether SHRs also ...

journal_title：Behavioral neuroscience

authors： Chess AC,Green JT

更新日期：2008-02-01 00:00:00

abstract：:Monkeys with conjoint bilateral lesions of the hippocampus and amygdala were impaired on four different tests of memory (delayed retention of object discriminations, concurrent discrimination, delayed response, and delayed nonmatching to sample). Because tests involving delays and distractions are known to be especial...

journal_title：Behavioral neuroscience

authors： Zola-Morgan S,Squire LR

更新日期：1985-02-01 00:00:00

abstract：:Lesion studies have shown that the avian hippocampus plays a crucial role in homing pigeon (Columba livia) navigation. Using the expression of the immediate early gene protein ZENK in intact pigeons, the authors found regional variation in hippocampal activation as a consequence of homing and, necessarily, the behavio...

journal_title：Behavioral neuroscience

authors： Shimizu T,Bowers AN,Budzynski CA,Kahn MC,Bingman VP

更新日期：2004-08-01 00:00:00

abstract：:The female steroid hormone 17beta-estradiol enhances synaptic transmission and the magnitude of longterm potentiation (LTP) in adult rodent hippocampal slices. Long-term depression (LTD), another form of synaptic plasticity, occurs more prominently in hippocampal slices from aged rodents. A decrease in LTP has been re...

journal_title：Behavioral neuroscience

authors： Foy MR,Baudry M,Foy JG,Thompson RF

更新日期：2008-04-01 00:00:00

abstract：:Rabbits received ibotenic acid lesions of the mediodorsal nucleus of the thalamus (MD) or sham lesions. These animals were compared on 4 sessions of Pavlovian eyeblink and heart rate conditioning, in which a tone was the conditioned stimulus and a paraorbital electrical shock was the unconditioned stimulus. Lesions of...

journal_title：Behavioral neuroscience

authors： Buchanan SL,Thompson RH

更新日期：1990-12-01 00:00:00

abstract：:Whether olfactory working memory involves verbal representations or neural images of odor per se remains unclear. This study investigated whether verbal representation influences performance in an olfactory delayed-match-to-sample task and used monorhinal presentation to generate hypotheses as to the underlying anatom...

journal_title：Behavioral neuroscience

authors： Yeshurun Y,Dudai Y,Sobel N

更新日期：2008-10-01 00:00:00

abstract：:Three experiments are reported whose purpose was to examine the effect of the cholinergic antagonist atropine on the acquisition of different learning tasks known to be sensitive or insensitive to impairment by hippocampal lesions; on the retention of performance acquired in the absence of the drug; and on memory cons...

journal_title：Behavioral neuroscience

authors： Hagan JJ,Tweedie F,Morris RG

更新日期：1986-08-01 00:00:00

abstract：:Bilateral ibotenic acid lesions of the lateral, but not the medial, parabrachial nucleus (PBN) blocked conditioned taste aversion (CTA) induced by morphine but not conditioned place preference induced by morphine. The same lateral PBN lesions also blocked conditioned place aversion produced by low intraperitoneal dose...

journal_title：Behavioral neuroscience

authors： Bechara A,Martin GM,Pridgar A,van der Kooy D

更新日期：1993-02-01 00:00:00

abstract：:The role of cholecystokinin (CCK) in food intake was investigated in rats by using BIM-18216, a novel CCK receptor antagonist. In rats fed 6 hr/day, BIM-18216 antagonized the reduction of food intake induced by exogenous CCK octapeptide (CCK-8; 4 micrograms/kg) in a dose-dependent manner and had a maximum effect at 1 ...

journal_title：Behavioral neuroscience

authors： Laferrere B,Nguyen M,Bonhomme G,Legall A,Basdevant A,Guy-Grand B

更新日期：1991-10-01 00:00:00

abstract：:Transecting the corpus callosum of postnatal day (P)1-6 rats disinhibits the production of spindle bursts (SBs) within primary somatosensory cortex (S1), most notably during periods of sleep-related myoclonic twitching. Here we investigated developmental changes in this callosally mediated disinhibition and its associ...

journal_title：Behavioral neuroscience

authors： Marcano-Reik AJ,Prasad T,Weiner JA,Blumberg MS

更新日期：2010-10-01 00:00:00

abstract：:Rats with perirhinal cortex lesions were sequentially trained in a rectangular water tank on a series of 3 visual discriminations, each between mirror-imaged stimuli. When these same discriminations were tested concurrently, the rats were forced to use a configural strategy to solve the problems effectively. There was...

journal_title：Behavioral neuroscience

authors： Aggleton JP,Albasser MM,Aggleton DJ,Poirier GL,Pearce JM

更新日期：2010-02-01 00:00:00

abstract：:Lesions of the medial preoptic area and/or the ventromedial hypothalamus resulted in an abrupt and immediate decline in courtship behavior in adult male Canadian red-sided garter snakes (Thamnophis sirtalis parietalis). Lesions of the more anterior portions of the preoptic area resulted in a more gradual, delayed decl...

journal_title：Behavioral neuroscience

authors： Friedman D,Crews D

更新日期：1985-10-01 00:00:00

abstract：:Function of the central nucleus of the amygdala (CeA) is critical to 2 aspects of attention in associative learning: the conditioning of orienting responses (ORs) to cues paired with food, and the enhancement of cue salience by the surprising omission of expected events. Such salience enhancements have been found to d...

journal_title：Behavioral neuroscience

authors： Esber GR,Torres-Tristani K,Holland PC

更新日期：2015-04-01 00:00:00

abstract：:Biological markers for acquisition and extinction of fear conditioning were studied in 40 individuals selected for displaying either good or poor acquisition of fear conditioning. as estimated by the skin conductance response. Participants with a short serotonin transporter (5-HTT) promoter allele or low monoamine oxi...

journal_title：Behavioral neuroscience

authors： Garpenstrand H,Annas P,Ekblom J,Oreland L,Fredrikson M

更新日期：2001-04-01 00:00:00

abstract：:In four experiments we reexamined the recent report by Labbe, Firl, Mufson, and Stein (1983) that fetal cortical tissue transplanted to an aspirative prefrontal cortical cavity in rats can ameliorate the learning impairments induced by the aspirative lesions. Healthy surviving grafts from young (E16) embryonic donors ...

journal_title：Behavioral neuroscience

authors： Dunnett SB,Ryan CN,Levin PD,Reynolds M,Bunch ST

更新日期：1987-08-01 00:00:00

abstract：:Cognitive functions, such as working memory, are disrupted in most psychiatric disorders. Many of these processes are believed to depend on the medial prefrontal cortex (mPFC). Traditionally, maze-based behavioral tasks, which have a strong exploratory component, have been used to study the role of the mPFC in working...

journal_title：Behavioral neuroscience

authors： Benoit LJ,Holt ES,Teboul E,Taliaferro JP,Kellendonk C,Canetta S

更新日期：2020-06-01 00:00:00

abstract：:Studies have shown that ovarian hormones protect against some of the cognitive deficits associated with aging. Although much of the literature in rodents has focused on hippocampal dependent tasks, studies suggest that tasks dependent on the prefrontal cortex are also influenced by ovarian hormones. The present study ...

journal_title：Behavioral neuroscience

authors： Chisholm NC,Juraska JM

更新日期：2012-02-01 00:00:00

abstract：:The authors measured food reinforcement, polymorphisms of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with th...

journal_title：Behavioral neuroscience

authors： Epstein LH,Temple JL,Neaderhiser BJ,Salis RJ,Erbe RW,Leddy JJ

更新日期：2007-10-01 00:00:00

abstract：:PDAPP transgenic mice have been shown to develop age dependently much of the cerebral histopathology associated with Alzheimer's disease. PDAPP mice (3-10 months old) were tested in a battery of memory tasks to determine whether they develop memory-behavioral deficits and whether these deficits occur before or after a...

journal_title：Behavioral neuroscience

authors： Dodart JC,Meziane H,Mathis C,Bales KR,Paul SM,Ungerer A

更新日期：1999-10-01 00:00:00

abstract：:Lesions of either the dorsomedial thalamus (DMT) or the parafascicular region of the thalamus (PFA) reduced rough-and-tumble social play in juvenile rats, as measured by frequency of pinning. Pinning was reduced by 33% in pups with DMT lesions and by 73% in pups with PFA lesions. Although PFA lesions had minimal effec...

journal_title：Behavioral neuroscience

authors： Siviy SM,Panksepp J

更新日期：1985-12-01 00:00:00

abstract：:The experiments addressed the question of whether certain modalities of stimulation are more effective in eliciting immobility-related, atropine-sensitive neocortical low-voltage fast activity and hippocampal rhythmical slow activity from the rabbit. More pronounced activation and less pronounced habituation followed ...

journal_title：Behavioral neuroscience

authors： Whishaw IQ,Dyck R

更新日期：1984-04-01 00:00:00

abstract：:When a passing shadow is presented to the crab (Chasmagnathus granulatus), an escape response is elicited that habituates after repeated stimulation. Results of previous papers suggest that this habituation might be mediated by endogenous opiates, entailing the postulate that opiates may inhibit the response to a dang...

journal_title：Behavioral neuroscience

authors： Maldonado H,Romano A,Lozada M

更新日期：1989-10-01 00:00:00