Abstract:
:Idazoxan, an alpha 2 adrenoceptor antagonist (2 mg/kg), enhanced novel object investigation in a holeboard in rats as previously reported (V. Devauges & S. J. Sara, 1990). Two weeks of 10 min/day in 37 degrees C water increased dopamine-beta-hydroxylase staining density in the locus coeruleus but did not enhance novel object investigation. In contrast to idazoxan, however, the warm water treatment increased rearing, center entries, and activity, a pattern previously described during tonic infusion of norepinephrine into the hippocampus. Correlations among dopamine-beta-hydroxylase measures and behavior reinforced these tonic norepinephrine/behavior associations. The behavioral effects across the idazoxan and warm water experiments support G. Aston-Jones et al.'s (1999) 2 modes of attention hypothesis for locus coeruleus function: Phasic locus coeruleus activity promotes focused attention; tonic locus coeruleus activity promotes scanning attention.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Mansour AA,Babstock DM,Penney JH,Martin GM,McLean JH,Harley CWdoi
10.1037/0735-7044.117.3.621subject
Has Abstractpub_date
2003-06-01 00:00:00pages
621-31issue
3eissn
0735-7044issn
1939-0084journal_volume
117pub_type
杂志文章abstract::This series of experiments investigated the role of a prefrontal cortical-dorsal striatal circuit in attention, using a continuous performance task of sustained and spatially divided visual attention. A unilateral excitotoxic lesion of the medial prefrontal cortex and a contralateral lesion of the medial caudate-putam...
journal_title:Behavioral neuroscience
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doi:10.1037//0735-7044.115.4.812
更新日期:2001-08-01 00:00:00
abstract::Chorda tympani nerve (CT) transection (CTX) raises sodium chloride (NaCl) taste detection threshold, but the effect of CT regeneration on NaCl threshold is unknown. This experiment examined whether CT regeneration supports normal NaCl threshold in the rat. Thresholds were measured with a 2-lever operant procedure. Thr...
journal_title:Behavioral neuroscience
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更新日期:2001-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0024404
更新日期:2011-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1037/bne0000332
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.115.3.614
更新日期:2001-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.107.5.812
更新日期:1993-10-01 00:00:00
abstract::The effects of lesions of the medial dorsal thalamic nucleus (MD) on blocking and latent inhibition (LI) of the rat eyeblink response were examined in the present study. Previous work has demonstrated that the cingulate cortex and related thalamic areas are involved in processing conditioning stimuli throughout traini...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
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更新日期:2008-02-01 00:00:00
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更新日期:2005-02-01 00:00:00
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2011-04-01 00:00:00
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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