Abstract:
:The effects of various doses (40 microg/kg/hr, 300 microg/kg/hr, 600 microg/kg/hr or placebo) of hydrocortisone on tasks assessing working and declarative memory function were measured in 4 groups of 10 young men. During the infusion, participants were given an item-recognition working memory task, a paired-associate declarative memory task, and a continuous performance task used to control possible concomitant effects of corticosteroids on vigilance. The results revealed significant acute effects of the highest dose of hydrocortisone on working memory function, without any significant effect on declarative memory function or arousal-vigilance performance. These results suggest that working memory is more sensitive than declarative memory to the acute elevations of corticosteroids, which could explain the detrimental effects of corticosteroids on acquisition and consolidation of information, as reported in the literature.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Lupien SJ,Gillin CJ,Hauger RLdoi
10.1037//0735-7044.113.3.420subject
Has Abstractpub_date
1999-06-01 00:00:00pages
420-30issue
3eissn
0735-7044issn
1939-0084journal_volume
113pub_type
临床试验,杂志文章,随机对照试验abstract::Recent evidence suggests that underlying patterns of cortical activation may partially account for individual differences in susceptibility to the effects of sleep deprivation. Here, functional magnetic resonance imaging (fMRI) was used to examine the activation of military pilots whose sleep-deprivation vulnerability...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.119.3.694
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.3.451
更新日期:1996-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.115.1.165
更新日期:2001-02-01 00:00:00
abstract::The aim of this study was to investigate the effects of postnatal choline supplementation on neurochemical and behavioral parameters in preweanling BALB/cByJ mice. Mouse pups were injected daily subcutaneously with choline chloride (0.85 mM/g body weight) from Postnatal Day (PND) 1 to PND 16. Pups performed a passive ...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::The patterns of intake of liquid diet and water were recorded in diet-deprived rats with septal lesions and neurologically intact controls during the first hour of diet access. The occurrences of grooming, resting/sleeping, and exploring were also recorded. Both groups of rats consumed similar amounts of diet in one m...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.100.3.416
更新日期:1986-06-01 00:00:00
abstract::Exercise can reduce symptoms of depression and anxiety in humans, but therapeutic effects of exercise in an animal model of stress-related mood disorders have yet to be demonstrated. In the current study, the authors investigated the ability of wheel running to reverse a long-lasting interference with shuttle box esca...
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pub_type: 杂志文章
doi:10.1037/0735-7044.121.5.992
更新日期:2007-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.120.2.477
更新日期:2006-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.5.935
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pub_type: 评论,杂志文章
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更新日期:2005-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0023250
更新日期:2011-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.6.1179
更新日期:1994-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.118.1.138
更新日期:2004-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.119.4.926
更新日期:2005-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/0735-7044.117.5.1006
更新日期:2003-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1037//0735-7044.116.6.1014
更新日期:2002-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0030249
更新日期:2012-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.6.1176
更新日期:1989-12-01 00:00:00
abstract::Amiloride-sensitive sodium channels in taste buds appear to play a key role in the response to NaCl stimulation, at least in adult rats. The researchers examined whether neonatal rats, which display an exaggerated preference for hypertonic NaCl solutions, lack functional amiloride-sensitive sodium channels. NaCl intak...
journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.108.5.981
更新日期:1994-10-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2007-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.106.2.315
更新日期:1992-04-01 00:00:00
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journal_title:Behavioral neuroscience
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00