Abstract：
:Amiloride-sensitive sodium channels in taste buds appear to play a key role in the response to NaCl stimulation, at least in adult rats. The researchers examined whether neonatal rats, which display an exaggerated preference for hypertonic NaCl solutions, lack functional amiloride-sensitive sodium channels. NaCl intake was significantly reduced by amiloride pretreatment, but water and ammonium chloride, NH4Cl, were unaffected. The researchers assessed whether the early appearance of amiloride sensitivity was mediated by effects on chorda tympani (CT) activity by sectioning the CT before testing. CT transection reduced intake of NaCl solutions and eliminated evidence of amiloride sensitivity. Amiloride sensitivity was also assessed by recording of whole-nerve CT activity at 8-11 days of age; the response to NaCl stimulation was significantly suppressed by amiloride. These data indicate that amiloride-sensitive sodium channels develop earlier than previously believed.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Sollars SI,Bernstein ILdoi
10.1037//0735-7044.108.5.981subject
Has Abstractpub_date
1994-10-01 00:00:00pages
981-7issue
5eissn
0735-7044issn
1939-0084journal_volume
108pub_type
杂志文章abstract：:Previous research emphasized the impact of traumatic brain injury on cholinergic systems and associated cognitive functions. Here we addressed the converse question: Because of the available evidence indicating cognitive and neuronal vulnerabilities in humans expressing low-capacity cholinergic systems or with declini...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/bne0000310
更新日期：2019-08-01 00:00:00
abstract：:The acoustic startle reflex (ASR) in rats is attenuated by a light paired with food or, in humans, by "pleasant" pictures. Rats were trained to barpress for lateral hypothalamus (LH) stimulation. ASR amplitudes were then measured at 4 intensities, with or without a light. Control rats that did not receive brain-stimul...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
abstract：:The role of the hippocampus in associative learning was investigated in 3 experiments with rats as subjects. Hippocampal rats were impaired in the acquisition of conditioned responding both when food was signaled by the insertion of a lever (Experiment 1) and when the presentation of auditory or visual events served a...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.105.4.499
更新日期：1991-08-01 00:00:00
abstract：:The present study was designed to evaluate the impact of neonatal injury on adult spinal plasticity in rats. Subjects were randomly assigned to 1 of 4 experimental conditions: (a) hind-paw injury at Postnatal Day (PD) 2, (b) hind-paw injury at PD 5, (c) anesthesia exposure only on PD 2, or (d) anesthesia exposure only...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/0735-7044.121.5.1095
更新日期：2007-10-01 00:00:00
abstract：:The patterns of intake of liquid diet and water were recorded in diet-deprived rats with septal lesions and neurologically intact controls during the first hour of diet access. The occurrences of grooming, resting/sleeping, and exploring were also recorded. Both groups of rats consumed similar amounts of diet in one m...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.100.3.416
更新日期：1986-06-01 00:00:00
abstract：:This study assessed the activity of head direction (HD) cells during performance of a spatial reference memory task on a radial arm maze. Rats were trained to select a maze arm located in a constant position in relation to a salient extramaze visual landmark. HD cell discharge properties remained relatively stable acr...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.111.1.3
更新日期：1997-02-01 00:00:00
abstract：:This study examines the effects of positive and negative feedback on performance during choice reaction time tasks to assess whether they differentially affect phasic arousal and tonic activation. Participants (N = 96) received either no feedback or signals of reward, punishment, or both during a semantic and a visuos...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.116.3.397
更新日期：2002-06-01 00:00:00
abstract：:Rats with unilateral dopamine (DA) depletion (hemiParkinson analogue rats) are impaired in using the contralateral (bad) limbs for skilled movements and for postural adjustments and compensate by using their good limbs in novel ways. The present study consisted of a reaching task in which compensatory adjustments usin...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.110.1.117
更新日期：1996-02-01 00:00:00
abstract：:The catechol-O-methyltransferase (COMT) val158met polymorphism has received attention in schizophrenia due to its role in prefrontal dopamine catabolism. Given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/a0026466
更新日期：2012-02-01 00:00:00
abstract：:Rats had repeated treatments with cocaine associated with a specific context (paired group). Evidence for classical conditioning of cocaine's motor-activity effects and context-specific behavioral sensitization to cocaine was obtained, relative to vehicle-treated (control) and pseudoconditioned (unpaired) groups. Only...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.110.6.1388
更新日期：1996-12-01 00:00:00
abstract：:The advent of the selective cholinergic toxin, 192 IgG-saporin, dramatically shaped subsequent research on the role of the basal forebrain in learning and memory. In particular, several articles (including the authors' 1995 Behavioral Neuroscience paper; M. G. Baxter, D. J. Bucci, L. K., Gorman, R. G. Wiley, & M. Gall...
journal_title：Behavioral neuroscience
pub_type： 评论,杂志文章
doi：10.1037/a0033781
更新日期：2013-10-01 00:00:00
abstract：:Dopamine in the medial preoptic area (MPOA) facilitates copulation in male rats, and nitric oxide (NO) regulates basal and female-stimulated MPOA dopamine release. Microinjection of L-nitro-arginine methyl ester (L-NAME, an NO synthesis inhibitor) into the MPOA blocked copulation in naive rats and impaired copulation ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/0735-7044.118.6.1317
更新日期：2004-12-01 00:00:00
abstract：:This study was conducted to investigate the effects of instruction types on hemispheric activation and accurate selection of spatial stimuli that had been previously presented at a subliminal level. Right-handed females randomly received either an "analytic" or a "holistic" instruction. Both groups first saw a series ...
journal_title：Behavioral neuroscience
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1037//0735-7044.100.3.343
更新日期：1986-06-01 00:00:00
abstract：:Finicky feeding refers to an animal's tendency to become more particular in accepting and choosing food as satiation is approached. We tested the hypothesis that finickiness in the blowfly is related to the balance between internal inhibition, generated by a full crop, and external sensory information, generated by or...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.97.4.541
更新日期：1983-08-01 00:00:00
abstract：:Galanin is a 29-amino-acid neuropeptide that is overexpressed in Alzheimer's disease (AD) and impairs performance on rodent learning and memory tasks. M40, a peptidergic galanin receptor ligand, blocks galanin-induced impairments on delayed non-matching-to-position (DNMTP). The present experiments used the 192IgG-sapo...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.111.3.552
更新日期：1997-06-01 00:00:00
abstract：:In humans, congenital deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a disorder known as the Lesch-Nyhan syndrome. Patients with this disorder exhibit a prominent neurobehavioral phenotype that results in part from dysfunction of catecholaminergic systems in the striatum. HPR...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.105.6.1004
更新日期：1991-12-01 00:00:00
abstract：:Acetylcholine (ACh) and noradrenaline (NA) release in the olfactory bulb (OB) of ewes was monitored using microdialysis. Both ACh and NA release increased at parturition in multiparous but not in primiparous ewes. However, vaginocervical stimulation performed 6 hr postpartum induced an increase of ACh and NA release i...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.107.4.662
更新日期：1993-08-01 00:00:00
abstract：:New Zealand male rabbits (Oryctolagus cuniculus) were trained on a trace eyeblink conditioning paradigm using a 250-ms tone conditioned stimulus, a 100-ms airpuff unconditioned stimulus, and a 500-ms trace interval. Rabbits received bilateral hippocampal aspirations either 1 day or 1 month after learning. Controls con...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.109.2.195
更新日期：1995-04-01 00:00:00
abstract：:Guinea pig pups that were separated from their mothers and placed into a novel environment for 90 min showed an increase in dopamine (DA) turnover (ratio of metabolites to DA) in the septum compared with undisturbed baseline controls. Pups placed into the novel environment with their mothers exhibited an intermediate ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.104.4.607
更新日期：1990-08-01 00:00:00
abstract：:The estradiol (E2), estrogen receptor-α (ERα), testosterone (T), and androgen receptor (AR) can contribute to anxiety, but whether they are associated with the reversion of prenatal adverse outcomes remains unclear. Here, we tested the interactive effects of prenatal maternal restraint stress and early postnatal short...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/bne0000094
更新日期：2015-12-01 00:00:00
abstract：:Ovariectomized female rats treated with estradiol benzoate (EB) and progesterone (P) were infused intracerebroventricularly with a low (200 ng) or high (1 microgram) dose of oxytocin (OT). The low dose of OT facilitated lordosis behavior only during the dark phase of the light-dark cycle in females that were pretreate...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.105.3.487
更新日期：1991-06-01 00:00:00
abstract：:Chorda tympani nerve (CT) transection in rats severely impairs NaCl taste detection. These rats can detect higher concentrations of NaCl, however, suggesting that remaining oral nerves maintain some salt sensibility. Rats were tested in a gustometer with a 2-response operant taste-detection task before and after sham ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/0735-7044.120.3.580
更新日期：2006-06-01 00:00:00
abstract：:Dopamine (DA)-containing neurons in the ventral tegmental area (VTA) are thought to play an important role in fear motivation. The primary objective of the present study was to determine the connection between DA D2, gamma aminobutyric acid (GABA)A, and benzodiazepine receptors in the VTA and footshock-associated emot...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：:Most of the studies focusing on the effect of stress on false memories by using psychosocial and physiological stressors yielded diverse results. In the present study, we systematically tested the effect of exogenous hydrocortisone using a false memory paradigm. In this placebo-controlled study, 37 healthy men and 38 ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/bne0000170
更新日期：2016-12-01 00:00:00
abstract：:Studies have shown that ovarian hormones protect against some of the cognitive deficits associated with aging. Although much of the literature in rodents has focused on hippocampal dependent tasks, studies suggest that tasks dependent on the prefrontal cortex are also influenced by ovarian hormones. The present study ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/a0026461
更新日期：2012-02-01 00:00:00
abstract：:The gustatory rejection response of the cabbage looper, Trichoplusia ni (Lepidoptera: Noctuidae), habituates to antifeedant compounds, allowing for the consumption of deterrent yet nontoxic plant materials. In the present study, we demonstrate that habituation to an antifeedant compound (quinine) persists through the ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/a0020741
更新日期：2010-10-01 00:00:00
abstract：:To determine whether dopamine signaling in the dorsal striatum is sufficient for performance of goal-directed behaviors, local dopamine production was restored in the dorsal striatum of dopamine-deficient (DD) mice through viral-mediated gene therapy. Virally rescued DD (vrDD) mice were tested for learning of an appet...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037/0735-7044.120.1.000
更新日期：2006-02-01 00:00:00
abstract：:Donoghue and Wise (1982) identified an area AGm in the rat that they take to be a nonprimary motor area. In the present experiments, therefore, this area was removed bilaterally in rats. The animals were poor at relearning a visual conditional motor task but were able to learn spatial delayed alternation as rapidly as...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.102.1.101
更新日期：1988-02-01 00:00:00
abstract：:The hippocampal formation (comprising the hippocampus proper, the dentate gyrus, and the subiculum) has been repeatedly implicated in information storage models of the mammalian brain. The precise nature of the hippocampal role in the storage of information has, however, remained elusive. Here it is proposed that the ...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.100.2.147
更新日期：1986-04-01 00:00:00
abstract：:Two different strains of mice, C57BL/6J and BALB/c, with hippocampal, cortical, or sham lesions, underwent contextual fear conditioning. In both strains, contextual fear, as measured by the freezing response, was significantly impaired in hippocampus-lesioned animals compared with sham control animals. Fear conditioni...
journal_title：Behavioral neuroscience
pub_type： 杂志文章
doi：10.1037//0735-7044.110.5.1177
更新日期：1996-10-01 00:00:00
