Abstract:
:New Zealand male rabbits (Oryctolagus cuniculus) were trained on a trace eyeblink conditioning paradigm using a 250-ms tone conditioned stimulus, a 100-ms airpuff unconditioned stimulus, and a 500-ms trace interval. Rabbits received bilateral hippocampal aspirations either 1 day or 1 month after learning. Controls consisted of time-matched sham-operated and neocortical aspirated rabbits. When retested on the trace paradigm, rabbits with hippocampal aspirations 1 day after learning were significantly and substantially impaired in the retention of trace conditioned responses. In contrast, rabbits that received hippocampal aspirations 1 month after training retained trace conditioned responses at a level comparable to that of the controls. Moreover, hippocampectomy had no effect on the retention of delay eyeblink conditioning. Thus, the hippocampus appears to be necessary for the retention of recently acquired, but not remotely acquired, trace conditioned responses.
journal_name
Behav Neuroscijournal_title
Behavioral neuroscienceauthors
Kim JJ,Clark RE,Thompson RFdoi
10.1037//0735-7044.109.2.195subject
Has Abstractpub_date
1995-04-01 00:00:00pages
195-203issue
2eissn
0735-7044issn
1939-0084journal_volume
109pub_type
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037/a0013727
更新日期:2009-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-02-01 00:00:00
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更新日期:2016-04-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.110.1.117
更新日期:1996-02-01 00:00:00
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更新日期:2004-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2001-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1037/0735-7044.121.4.751
更新日期:2007-08-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1986-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1990-08-01 00:00:00
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更新日期:2010-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1037//0735-7044.103.2.373
更新日期:1989-04-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.103.1.170
更新日期:1989-02-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:10.1037//0735-7044.116.5.912
更新日期:2002-10-01 00:00:00
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更新日期:1994-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1985-12-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
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journal_title:Behavioral neuroscience
pub_type: 杂志文章
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更新日期:1983-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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