Amphetamine-induced behavioral phenotype in a hypoxanthine-guanine phosphoribosyltransferase-deficient mouse model of Lesch-Nyhan syndrome.

abstract：:Classical conditioning of the rabbit eyeblink response was used to study the effects of cerebellar lesions on performance in animals trained with low-intensity unconditioned stimuli (US). Animals were trained with 1 of 2 low-intensity corneal-airpuff USs paired with a tone-conditioned stimulus. This study confirms ear...

journal_title：Behavioral neuroscience

authors： Ivkovich D,Lockard JM,Thompson RF

更新日期：1993-06-01 00:00:00

abstract：:Previous literature suggests that the hippocampus subserves processes associated with the encoding of novel information. To investigate the role of different subregions of the hippocampus, the authors made neurotoxic lesions in different subregions of the dorsal hippocampus (i.e., CA1, dentate gyrus [DG], or CA3) of r...

journal_title：Behavioral neuroscience

authors： Lee I,Hunsaker MR,Kesner RP

更新日期：2005-02-01 00:00:00

abstract：:It has been proposed that the cognitive dysfunction observed in patients with schizophrenia reflects a failure in cognitive control, in particular an inability to use task-relevant information to guide behavior. Using a prefrontal-dependent task designed to reflect aspects of cue and response conflict seen in human co...

journal_title：Behavioral neuroscience

authors： Haddon JE,Killcross S

更新日期：2011-06-01 00:00:00

abstract：:Guinea pig pups that were separated from their mothers and placed into a novel environment for 90 min showed an increase in dopamine (DA) turnover (ratio of metabolites to DA) in the septum compared with undisturbed baseline controls. Pups placed into the novel environment with their mothers exhibited an intermediate ...

journal_title：Behavioral neuroscience

authors： Tamborski A,Lucot JB,Hennessy MB

更新日期：1990-08-01 00:00:00

abstract：:Biological markers for acquisition and extinction of fear conditioning were studied in 40 individuals selected for displaying either good or poor acquisition of fear conditioning. as estimated by the skin conductance response. Participants with a short serotonin transporter (5-HTT) promoter allele or low monoamine oxi...

journal_title：Behavioral neuroscience

authors： Garpenstrand H,Annas P,Ekblom J,Oreland L,Fredrikson M

更新日期：2001-04-01 00:00:00

abstract：:The role of thyroid hormones in vertebrate development has been well documented for several decades. As hypothyroidism during critical periods of development can cause defects to the development of every major organ system, including brain, eye, and general morphology, we hypothesized that hypothyroidism would affect ...

journal_title：Behavioral neuroscience

authors： Reider M,Connaughton VP

更新日期：2015-10-01 00:00:00

abstract：:The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a conditioned stimulus (CS) in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Experiment 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexp...

journal_title：Behavioral neuroscience

authors： Holland PC,Gallagher M

更新日期：1993-04-01 00:00:00

abstract：:The effects of dl-cathinone on milk intake and motor activity were investigated in bottle- and cannula-fed rats. Acute injections of cathinone produced dose-dependent increases in activity in both groups but only produced decreased intake in bottle-fed rats. With chronic injections, tolerance to the suppression of int...

journal_title：Behavioral neuroscience

authors： Wolgin DL,Munoz JR

更新日期：2006-04-01 00:00:00

abstract：:Lesions of the medial preoptic area and/or the ventromedial hypothalamus resulted in an abrupt and immediate decline in courtship behavior in adult male Canadian red-sided garter snakes (Thamnophis sirtalis parietalis). Lesions of the more anterior portions of the preoptic area resulted in a more gradual, delayed decl...

journal_title：Behavioral neuroscience

authors： Friedman D,Crews D

更新日期：1985-10-01 00:00:00

abstract：:In infant rats, administration of the alpha2 adrenoceptor agonist clonidine simultaneously evokes ultrasound production and bradycardia. In this study the authors examined in 8-day-old rats whether these 2 responses to clonidine are causally related. In Experiment 1 pups were pretreated with saline or prenalterol (0.1...

journal_title：Behavioral neuroscience

authors： Blumberg MS,Kreber LA,Sokoloff G,Kent KJ

更新日期：2000-06-01 00:00:00

abstract：:Fetal and maternal data were monitored serially at 6 gestational ages from 20 to 38 weeks in 195 Peruvian fetuses. Digitized data included fetal heart rate and motor activity, as well as maternal heart rate and electrodermal conductance. Time series analysis evaluated the development of synchrony in 2 streams of fetal...

journal_title：Behavioral neuroscience

authors： DiPietro JA,Caulfield LE,Irizarry RA,Chen P,Merialdi M,Zavaleta N

更新日期：2006-06-01 00:00:00

abstract：:This study examined the hypothesis that defensive responsiveness induced by threatening stimuli of biological origin is mediated by the action of endogenous corticotropin-releasing factor (CRF). Rats were exposed for 15 min to a large open field containing a small chamber. Twenty-four hours later, rats received intrac...

journal_title：Behavioral neuroscience

authors： Takahashi LK,Kalin NH,Baker EW

更新日期：1990-04-01 00:00:00

abstract：:Ovariectomized female rats treated with estradiol benzoate (EB) and progesterone (P) were infused intracerebroventricularly with a low (200 ng) or high (1 microgram) dose of oxytocin (OT). The low dose of OT facilitated lordosis behavior only during the dark phase of the light-dark cycle in females that were pretreate...

journal_title：Behavioral neuroscience

authors： Schumacher M,Coirini H,Pfaff DW,McEwen BS

更新日期：1991-06-01 00:00:00

abstract：:The possible modulatory role of motor cortex in classical conditioning of the eyeblink response was examined by ablating anterior neocortex in rabbits and training them with an auditory conditioned stimulus (CS) and an airpuff unconditioned stimulus (US) in either a delay (Experiment 1) or a trace (Experiment 2) condi...

journal_title：Behavioral neuroscience

authors： Ivkovich D,Thompson RF

更新日期：1997-08-01 00:00:00

abstract：:Fear reactions of rats given bilateral lesions to the septum, hippocampus, or amygdala were compared with those of rats given sham lesions, in 2 animal models of anxiety: the shock-probe burying test and the elevated plus-maze test. Septal lesions produced anxiolytic effects in both tests (i.e., an increase in open-ar...

journal_title：Behavioral neuroscience

authors： Treit D,Menard J

更新日期：1997-06-01 00:00:00

abstract：:Mice with genetically associated variations in the number and density of granule cells in the dentate gyrus were tested for open-field activity, spatial maze learning, and two-way avoidance conditioning. The number of granule cells was not associated with any behavior measured. Only avoidance conditioning was related ...

journal_title：Behavioral neuroscience

authors： Wimer C,Wimer RE,Wimer JS

更新日期：1983-12-01 00:00:00

abstract：:The purpose of this experiment was to evaluate the extent to which continued drug discrimination training during chronic drug treatment affects the development of tolerance. Rats were trained to discriminate distilled water from 0.75 mg/kg amphetamine in a two-lever drug discrimination task. Two groups were then given...

journal_title：Behavioral neuroscience

authors： Caul WF,Burgin KL,Barrett RJ

更新日期：1989-04-01 00:00:00

abstract：:An acoustic stimulus previously paired with footshock elicits stereotyped increases in arterial pressure and heart rate and induces freezing behavior in freely behaving rats. Although the arterial pressure and freezing responses differ between groups given paired and random presentations of the tone and shock, the inc...

journal_title：Behavioral neuroscience

authors： Iwata J,LeDoux JE

更新日期：1988-02-01 00:00:00

abstract：:Previous research shows that prenatal binge ethanol exposure during gestation days (GD) 17 to 20 of the rat, increases postnatal ethanol intake and enhances ethanol's palatability, both effects being mediated by the opioid system. The amniotic fluid of the last period of gestation (GD 20) of the rat has been found to ...

journal_title：Behavioral neuroscience

authors： Díaz-Cenzano E,Chotro MG

更新日期：2010-06-01 00:00:00

abstract：:Previous research conducted in monkeys and rats has established that the perirhinal cortex is critically involved in object- or stimulus-recognition memory, whereas other research suggests this region may contribute to memory for object discriminations. These findings do not rule out the possibility that the perirhina...

journal_title：Behavioral neuroscience

authors： Wiig KA,Burwell RD

更新日期：1998-08-01 00:00:00

abstract：:Female songbirds use male songs as an important criterion for mate selection. Several studies have reported that female songbirds prefer complex songs to other song types. In a recent study, the authors found that song responsiveness in female zebra finches (Taeniopygia guttata) is strongly modulated by circulating es...

journal_title：Behavioral neuroscience

authors： Vyas A,Harding C,McGowan J,Snare R,Bogdan D

更新日期：2008-10-01 00:00:00

abstract：:Two causes of forgetting have been promulgated: memory trace decay and retroactive interference. The authors show that forgetting is an active process requiring both new learning and memory. In the present (1)Lymnaea model system, prevention of new learning of a conflicting association, inhibition of memory consolidat...

journal_title：Behavioral neuroscience

authors： Sangha S,Scheibenstock A,Martens K,Varshney N,Cooke R,Lukowiak K

更新日期：2005-06-01 00:00:00

abstract：:In 3 experiments, the authors examined the role of adenosine regulation in escape deficits produced by earlier exposure to inescapable shock in rats (learned helplessness). Adenosine analogs injected before escape testing mimicked the effect of earlier inescapable shock, with the magnitude of the deficit varying with ...

journal_title：Behavioral neuroscience

authors： Minor TR,Winslow JL,Chang WC

更新日期：1994-04-01 00:00:00

abstract：:To explore the role of the cerebellum in sustained attention, the authors tested lurcher, wildtype, and lurcher chimeric mice with zero, normal, and variable numbers of Purkinje cells, respectively, in a previously validated task of sustained attention. Results indicate that lurcher mice had a deficit in performance l...

journal_title：Behavioral neuroscience

authors： Martin LA,Goldowitz D,Mittleman G

更新日期：2006-04-01 00:00:00

abstract：:The acquisition and performance of a self-paced test of spatial divided attention linked with frontal cortex function were assessed in postpubertal (> 60 days) normal or gonadectomized male and female rats. Males were more accurate at detecting relatively brief visual stimuli than females, but this difference was elim...

journal_title：Behavioral neuroscience

authors： Jentsch JD,Taylor JR

更新日期：2003-02-01 00:00:00

abstract：:In 2 experiments, the development of adjuvant arthritis (an experimental autoimmune disease) was inhibited by exposing rats to a flavored solution that had previously been paired with injections of cyclosporine (an immunodepressive drug) compared with rats with the same history but exposed to a flavored solution that ...

journal_title：Behavioral neuroscience

authors： Klosterhalfen S,Klosterhalfen W

更新日期：1990-10-01 00:00:00

abstract：:Regulation of energy intake depends in part on both memory for prior food intake and internal signals of hunger and satiety. These functions are both mediated by the hippocampus, a brain structure that animal studies have shown to be impaired after maintenance on high fat and refined sugar (HFS) diets. Study 1, using ...

journal_title：Behavioral neuroscience

authors： Francis HM,Stevenson RJ

更新日期：2011-12-01 00:00:00

abstract：:Auditory streaming describes a percept in which a sequential series of sounds either is segregated into different streams or is integrated into one stream based on differences in their spectral or temporal characteristics. This phenomenon has been analyzed in human subjects (psychophysics) and European starlings (neur...

journal_title：Behavioral neuroscience

authors： Dolležal LV,Itatani N,Günther S,Klump GM

更新日期：2012-12-01 00:00:00

abstract：:Neuropsin (kallikrein-related peptidase 8) is concentrated in the hippocampus, amygdala, olfactory bulb, and prefrontal cortex. Earlier studies showed that protease deficiency causes a significant impairment of early-phase long-term potentiation in the Schaffer collateral pathway and hippocampus-dependent memory in th...

journal_title：Behavioral neuroscience

authors： Horii Y,Yamasaki N,Miyakawa T,Shiosaka S

更新日期：2008-06-01 00:00:00

abstract：:Quipazine is a 5-HT2A-receptor agonist that has been used to induce motor activity and promote recovery of function after spinal cord injury in neonatal and adult rodents. Sensory stimulation also activates sensory and motor circuits and promotes recovery after spinal cord injury. In rats, tail pinching is an effectiv...

journal_title：Behavioral neuroscience

authors： Swann HE,Kauer SD,Allmond JT,Brumley MR

更新日期：2017-02-01 00:00:00